Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS__AND_SUBSEQUENT_BINDING_TO_43S |
| Enrichment Score (ES) | -0.73522234 |
| Normalized Enrichment Score (NES) | -1.7453738 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.28138727 |
| FWER p-Value | 0.551 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | EIF2S2 | 1417712_at 1417713_at 1441023_at 1448819_at 1448820_a_at 1456617_a_at | 281 | 1.952 | 0.0842 | No | ||
| 2 | EIF4EBP1 | 1417562_at 1417563_at 1434976_x_at | 1638 | 0.571 | 0.0507 | No | ||
| 3 | RPS3A | 1422475_a_at | 2915 | 0.310 | 0.0079 | No | ||
| 4 | RPS3 | 1435151_a_at 1447563_at 1455600_at | 3632 | 0.238 | -0.0129 | No | ||
| 5 | EIF2S1 | 1440272_at 1452662_a_at | 4119 | 0.204 | -0.0250 | No | ||
| 6 | EIF4G1 | 1427036_a_at 1427037_at 1438686_at | 4282 | 0.193 | -0.0228 | No | ||
| 7 | RPS24 | 1436064_x_at 1436500_at 1453362_x_at 1455195_at 1456628_x_at | 5158 | 0.151 | -0.0552 | No | ||
| 8 | RPS21 | 1430288_x_at 1433549_x_at 1433721_x_at 1434358_x_at | 5877 | 0.125 | -0.0818 | No | ||
| 9 | RPS14 | 1436586_x_at | 6345 | 0.111 | -0.0976 | No | ||
| 10 | RPS23 | 1460175_at | 6930 | 0.094 | -0.1196 | No | ||
| 11 | RPS28 | 1451101_a_at | 8388 | 0.059 | -0.1832 | No | ||
| 12 | RPS11 | 1424000_a_at | 9553 | 0.033 | -0.2347 | No | ||
| 13 | RPS2 | 1431766_x_at | 10619 | 0.012 | -0.2827 | No | ||
| 14 | RPS25 | 1430978_at 1451068_s_at | 10979 | 0.004 | -0.2988 | No | ||
| 15 | EIF4A1 | 1427058_at 1430980_a_at 1434985_a_at | 11569 | -0.008 | -0.3253 | No | ||
| 16 | FAU | 1417452_a_at | 12027 | -0.018 | -0.3453 | No | ||
| 17 | RPSA | 1416196_at 1448245_at | 12918 | -0.037 | -0.3841 | No | ||
| 18 | RPS20 | 1456373_x_at 1456436_x_at | 13098 | -0.041 | -0.3902 | No | ||
| 19 | RPS5 | 1416054_at | 13721 | -0.055 | -0.4158 | No | ||
| 20 | RPS19 | 1449243_a_at 1460442_at | 14222 | -0.068 | -0.4353 | No | ||
| 21 | RPS4X | 1416276_a_at | 14898 | -0.086 | -0.4618 | No | ||
| 22 | RPS17 | 1437510_x_at 1438501_at 1438986_x_at 1455662_x_at 1457940_at 1459986_a_at | 15183 | -0.094 | -0.4701 | No | ||
| 23 | RPS15A | 1453467_s_at 1457726_at | 15280 | -0.097 | -0.4697 | No | ||
| 24 | RPS15 | 1416088_a_at 1416089_at | 16772 | -0.147 | -0.5304 | No | ||
| 25 | EIF4B | 1426378_at 1426379_at 1426380_at | 18572 | -0.262 | -0.5995 | No | ||
| 26 | EIF4E | 1450909_at 1457489_at 1459371_at | 19374 | -0.356 | -0.6184 | Yes | ||
| 27 | PABPC1 | 1418883_a_at 1419500_at 1453840_at | 21934 | -6.759 | -0.3992 | Yes | ||
| 28 | RPS16 | 1416404_s_at 1437196_x_at 1455835_at | 21936 | -8.031 | 0.0000 | Yes |
