Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | CELLMAP_ALPHA6BETA4INTEGRIN |
| Enrichment Score (ES) | -0.58667785 |
| Normalized Enrichment Score (NES) | -1.5505977 |
| Nominal p-value | 0.021825397 |
| FDR q-value | 0.85207266 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | YWHAB | 1420878_a_at 1420879_a_at 1420880_a_at 1436783_x_at 1438708_x_at 1455815_a_at | 1221 | 0.733 | -0.0279 | No | ||
| 2 | SMAD2 | 1420634_a_at 1458304_at | 1601 | 0.582 | -0.0231 | No | ||
| 3 | EIF4EBP1 | 1417562_at 1417563_at 1434976_x_at | 1638 | 0.571 | -0.0030 | No | ||
| 4 | RAC1 | 1423734_at 1437674_at 1451086_s_at | 2072 | 0.450 | -0.0056 | No | ||
| 5 | MST1R | 1420461_at | 2416 | 0.382 | -0.0068 | No | ||
| 6 | YWHAQ | 1420828_s_at 1420829_a_at 1420830_x_at 1432842_s_at 1437608_x_at 1454378_at 1460590_s_at 1460621_x_at | 2563 | 0.359 | 0.0002 | No | ||
| 7 | AR | 1422982_at 1437064_at 1446340_at 1455647_at | 2796 | 0.324 | 0.0020 | No | ||
| 8 | DSP | 1427610_at 1435493_at 1435494_s_at | 3088 | 0.289 | -0.0004 | No | ||
| 9 | VIM | 1438118_x_at 1450641_at 1456292_a_at | 3705 | 0.233 | -0.0196 | No | ||
| 10 | GRB2 | 1418508_a_at 1449111_a_at | 3849 | 0.223 | -0.0177 | No | ||
| 11 | SFN | 1448612_at | 4662 | 0.174 | -0.0482 | No | ||
| 12 | YWHAZ | 1416102_at 1416103_at 1436971_x_at 1436981_a_at 1439005_x_at 1443893_at 1448218_s_at 1448219_a_at | 4911 | 0.162 | -0.0533 | No | ||
| 13 | ABL1 | 1423999_at 1441291_at 1444134_at 1445153_at | 4990 | 0.158 | -0.0509 | No | ||
| 14 | PIK3R2 | 1418463_at | 5301 | 0.146 | -0.0595 | No | ||
| 15 | FYN | 1417558_at 1441647_at 1448765_at | 5640 | 0.133 | -0.0699 | No | ||
| 16 | RHOA | 1437628_s_at | 5643 | 0.133 | -0.0649 | No | ||
| 17 | MMP7 | 1449478_at | 6332 | 0.111 | -0.0921 | No | ||
| 18 | CLCA2 | 1419463_at | 7783 | 0.072 | -0.1556 | No | ||
| 19 | SRC | 1423240_at 1450918_s_at | 7866 | 0.070 | -0.1567 | No | ||
| 20 | YES1 | 1418470_at 1449090_a_at 1456843_at 1458878_at | 8419 | 0.058 | -0.1797 | No | ||
| 21 | PRKCA | 1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at | 10127 | 0.021 | -0.2569 | No | ||
| 22 | ITGB4 | 1427387_a_at | 10337 | 0.017 | -0.2658 | No | ||
| 23 | RPSA | 1416196_at 1448245_at | 12918 | -0.037 | -0.3822 | No | ||
| 24 | CLCA1 | 1417852_x_at 1417853_at | 13560 | -0.051 | -0.4096 | No | ||
| 25 | COL17A1 | 1418799_a_at | 13884 | -0.059 | -0.4221 | No | ||
| 26 | MET | 1422990_at | 15294 | -0.097 | -0.4827 | No | ||
| 27 | ERBB2 | 1424919_at | 15362 | -0.099 | -0.4820 | No | ||
| 28 | BAD | 1416582_a_at 1416583_at | 15444 | -0.101 | -0.4819 | No | ||
| 29 | YWHAH | 1416004_at | 15732 | -0.110 | -0.4908 | No | ||
| 30 | PIK3CG | 1422707_at 1422708_at | 17650 | -0.192 | -0.5711 | No | ||
| 31 | PLEC1 | 1419835_s_at 1434610_at 1437554_at | 17773 | -0.199 | -0.5691 | No | ||
| 32 | DST | 1421117_at 1421276_a_at 1423626_at 1442395_at 1446943_at 1450119_at 1458075_at 1459098_at 1459356_at | 17924 | -0.210 | -0.5680 | No | ||
| 33 | PIK3R3 | 1445097_at 1447068_at 1456482_at | 17965 | -0.212 | -0.5617 | No | ||
| 34 | EGFR | 1424932_at 1432647_at 1435888_at 1451530_at 1454313_at 1457563_at 1460420_a_at | 18510 | -0.256 | -0.5768 | Yes | ||
| 35 | CD151 | 1420921_at 1424093_x_at 1427525_at 1437670_x_at 1440507_at 1451232_at 1456085_x_at | 18727 | -0.277 | -0.5761 | Yes | ||
| 36 | CASP3 | 1426165_a_at 1430192_at 1449839_at | 18928 | -0.295 | -0.5740 | Yes | ||
| 37 | FRAP1 | 1417592_at 1436267_a_at 1446185_at 1459625_at | 19154 | -0.324 | -0.5720 | Yes | ||
| 38 | PIK3CB | 1445731_at 1453069_at | 19191 | -0.330 | -0.5611 | Yes | ||
| 39 | EIF4E | 1450909_at 1457489_at 1459371_at | 19374 | -0.356 | -0.5559 | Yes | ||
| 40 | SMAD3 | 1450471_at 1450472_s_at 1454960_at | 20043 | -0.481 | -0.5681 | Yes | ||
| 41 | SHC1 | 1422853_at 1422854_at | 20174 | -0.514 | -0.5545 | Yes | ||
| 42 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 20260 | -0.543 | -0.5377 | Yes | ||
| 43 | PAK1 | 1420979_at 1420980_at 1450070_s_at 1459029_at | 20671 | -0.684 | -0.5304 | Yes | ||
| 44 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 21137 | -1.017 | -0.5130 | Yes | ||
| 45 | ITGA6 | 1422444_at 1422445_at | 21588 | -1.745 | -0.4671 | Yes | ||
| 46 | PTK2 | 1423059_at 1430827_a_at 1439198_at 1440082_at 1441475_at 1443384_at 1445137_at | 21633 | -1.852 | -0.3987 | Yes | ||
| 47 | PRKCD | 1422847_a_at 1442256_at | 21729 | -2.225 | -0.3183 | Yes | ||
| 48 | MBP | 1419646_a_at 1425263_a_at 1425264_s_at 1433532_a_at 1436201_x_at 1451961_a_at 1454651_x_at 1456228_x_at | 21867 | -3.444 | -0.1936 | Yes | ||
| 49 | YWHAE | 1426384_a_at 1426385_x_at 1435702_s_at 1438839_a_at 1440841_at 1457173_at | 21922 | -5.169 | 0.0006 | Yes |
