Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | ENDOSOME |
| Enrichment Score (ES) | -0.56536764 |
| Normalized Enrichment Score (NES) | -1.6096048 |
| Nominal p-value | 0.001996008 |
| FDR q-value | 0.71078444 |
| FWER p-Value | 0.997 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | FYN | 1417558_at 1441647_at 1448765_at | 384 | 2.271 | 0.0429 | No | ||
| 2 | TFRC | 1422966_a_at 1422967_a_at 1452661_at AFFX-TransRecMur/X57349_3_at AFFX-TransRecMur/X57349_5_at AFFX-TransRecMur/X57349_M_at | 611 | 1.759 | 0.0794 | No | ||
| 3 | CCR5 | 1422259_a_at 1422260_x_at 1424727_at | 3012 | 0.486 | -0.0174 | No | ||
| 4 | CD79A | 1418830_at | 3670 | 0.389 | -0.0370 | No | ||
| 5 | SLC30A3 | 1460654_at | 4062 | 0.348 | -0.0456 | No | ||
| 6 | M6PRBP1 | 1416424_at | 4187 | 0.338 | -0.0423 | No | ||
| 7 | RAB5B | 1422119_at 1437446_at | 4257 | 0.333 | -0.0366 | No | ||
| 8 | CLN3 | 1417551_at 1457789_at | 5898 | 0.240 | -0.1052 | No | ||
| 9 | LDLRAP1 | 1424378_at 1457162_at | 6408 | 0.219 | -0.1226 | No | ||
| 10 | VAMP8 | 1420624_a_at | 6629 | 0.211 | -0.1270 | No | ||
| 11 | NF2 | 1421820_a_at 1427708_a_at 1450382_at 1451829_a_at | 6675 | 0.209 | -0.1235 | No | ||
| 12 | FPR1 | 1450808_at | 6798 | 0.204 | -0.1237 | No | ||
| 13 | CTSE | 1418989_at | 6836 | 0.202 | -0.1200 | No | ||
| 14 | MAL | 1417275_at 1432558_a_at | 6952 | 0.198 | -0.1200 | No | ||
| 15 | ANKRD27 | 1425112_at 1454717_at | 7373 | 0.183 | -0.1343 | No | ||
| 16 | RABEPK | 1433041_at 1448046_at 1451487_at 1454449_at | 7665 | 0.174 | -0.1430 | No | ||
| 17 | LHCGR | 1450192_at | 7725 | 0.173 | -0.1411 | No | ||
| 18 | IL15 | 1418219_at | 8300 | 0.156 | -0.1631 | No | ||
| 19 | AVPR1B | 1422204_at | 8706 | 0.143 | -0.1778 | No | ||
| 20 | TOM1L1 | 1439337_at 1451117_a_at | 8907 | 0.138 | -0.1833 | No | ||
| 21 | PAMCI | 1427942_at | 9162 | 0.131 | -0.1914 | No | ||
| 22 | SYT3 | 1417708_at | 9470 | 0.122 | -0.2022 | No | ||
| 23 | RNF32 | 1431365_at 1432156_a_at 1453666_at | 9886 | 0.111 | -0.2182 | No | ||
| 24 | ATP7B | 1421563_at 1446004_at 1450283_at | 10522 | 0.095 | -0.2447 | No | ||
| 25 | VPS4B | 1417007_a_at 1457067_at 1460104_at | 11361 | 0.074 | -0.2810 | No | ||
| 26 | TPT1 | 1416642_a_at 1416643_at | 11451 | 0.072 | -0.2832 | No | ||
| 27 | TM9SF2 | 1423295_at 1455875_x_at 1456742_x_at 1460331_at | 12714 | 0.041 | -0.3398 | No | ||
| 28 | BACE1 | 1421824_at 1421825_at 1436956_at 1450384_at 1455826_a_at | 12912 | 0.035 | -0.3479 | No | ||
| 29 | AVPR1A | 1418603_at 1418604_at | 13238 | 0.026 | -0.3620 | No | ||
| 30 | WDFY1 | 1424749_at 1435588_at 1437358_at 1447543_at 1453426_a_at | 14464 | -0.012 | -0.4177 | No | ||
| 31 | AVPR2 | 1450277_at | 15474 | -0.053 | -0.4624 | No | ||
| 32 | VPS29 | 1417659_at 1417660_s_at 1440641_at 1455302_at | 15506 | -0.054 | -0.4624 | No | ||
| 33 | STS | 1421500_at | 16132 | -0.089 | -0.4886 | No | ||
| 34 | DNER | 1423671_at 1456379_x_at | 16152 | -0.090 | -0.4871 | No | ||
| 35 | CTNS | 1416274_at 1456450_at | 16186 | -0.092 | -0.4861 | No | ||
| 36 | ALS2 | 1417783_at 1417784_at 1431608_at 1446183_at | 16495 | -0.112 | -0.4972 | No | ||
| 37 | VPS28 | 1448447_at | 16641 | -0.123 | -0.5006 | No | ||
| 38 | LAMP2 | 1416343_a_at 1416344_at 1428094_at 1434503_s_at | 16989 | -0.153 | -0.5124 | No | ||
| 39 | YKT6 | 1448464_at 1460191_at | 17236 | -0.178 | -0.5189 | No | ||
| 40 | RABEP1 | 1421305_x_at 1426023_a_at 1427448_at 1443856_at 1444930_at 1459494_at | 17265 | -0.181 | -0.5153 | No | ||
| 41 | EGFR | 1424932_at 1432647_at 1435888_at 1451530_at 1454313_at 1457563_at 1460420_a_at | 17646 | -0.231 | -0.5265 | No | ||
| 42 | VPS35 | 1415783_at 1415784_at | 18135 | -0.300 | -0.5408 | No | ||
| 43 | ADRB2 | 1437302_at | 18181 | -0.306 | -0.5348 | No | ||
| 44 | LYST | 1421384_at 1425973_at 1434674_at | 18202 | -0.309 | -0.5274 | No | ||
| 45 | TSG101 | 1417004_at | 18785 | -0.415 | -0.5430 | No | ||
| 46 | VAMP4 | 1422895_at 1422896_at 1434796_at | 18860 | -0.432 | -0.5349 | No | ||
| 47 | SNX17 | 1455955_s_at | 19528 | -0.598 | -0.5494 | Yes | ||
| 48 | RAB14 | 1415686_at 1419243_at 1419244_a_at 1419245_at 1419246_s_at 1439687_at 1441992_at | 19555 | -0.609 | -0.5344 | Yes | ||
| 49 | STX6 | 1423038_at 1431646_a_at 1440585_at 1441133_at 1450844_at 1458920_at 1460004_x_at | 19590 | -0.619 | -0.5195 | Yes | ||
| 50 | ARF6 | 1418822_a_at 1418823_at 1418824_at | 20186 | -0.844 | -0.5242 | Yes | ||
| 51 | ATP7A | 1418774_a_at 1436921_at | 20310 | -0.898 | -0.5059 | Yes | ||
| 52 | BET1L | 1422980_a_at 1426372_a_at 1430549_at 1453570_x_at | 21040 | -1.467 | -0.5002 | Yes | ||
| 53 | RAB21 | 1437741_at 1437742_at 1447497_at | 21223 | -1.740 | -0.4622 | Yes | ||
| 54 | RAB22A | 1424503_at 1424504_at 1451379_at 1454988_s_at | 21228 | -1.749 | -0.4158 | Yes | ||
| 55 | ANKFY1 | 1417685_at 1443654_at | 21551 | -2.298 | -0.3694 | Yes | ||
| 56 | ADRA2C | 1422335_at 1435296_at 1439762_x_at 1457328_at | 21712 | -2.864 | -0.3004 | Yes | ||
| 57 | IGF2R | 1424111_at 1424112_at 1440979_at 1445966_at 1457356_at | 21727 | -2.906 | -0.2237 | Yes | ||
| 58 | STEAP2 | 1428636_at 1438773_at 1442359_at 1444290_at 1446071_at | 21749 | -3.015 | -0.1444 | Yes | ||
| 59 | LAMP1 | 1415880_a_at 1460096_at | 21924 | -5.743 | 0.0005 | Yes |
