Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY |
| Enrichment Score (ES) | -0.65699023 |
| Normalized Enrichment Score (NES) | -1.6906072 |
| Nominal p-value | 0.005905512 |
| FDR q-value | 0.17281201 |
| FWER p-Value | 0.949 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 525 | 1.916 | 0.0325 | No | ||
| 2 | PSCD3 | 1418758_a_at 1431707_a_at 1446268_at | 1498 | 0.966 | 0.0167 | No | ||
| 3 | YWHAB | 1420878_a_at 1420879_a_at 1420880_a_at 1436783_x_at 1438708_x_at 1455815_a_at | 1612 | 0.912 | 0.0384 | No | ||
| 4 | YWHAG | 1420816_at 1420817_at 1450012_x_at 1459693_x_at | 2251 | 0.668 | 0.0290 | No | ||
| 5 | CDKN2A | 1450140_a_at | 2909 | 0.506 | 0.0139 | No | ||
| 6 | RPS6KA1 | 1416896_at | 5001 | 0.282 | -0.0732 | No | ||
| 7 | BTK | 1422755_at | 5693 | 0.249 | -0.0974 | No | ||
| 8 | RPS6KB1 | 1428849_at 1446376_at 1454956_at 1457562_at 1459951_at 1460705_at | 6240 | 0.226 | -0.1157 | No | ||
| 9 | RPS6KA2 | 1417542_at 1417543_at 1441311_at | 7722 | 0.173 | -0.1782 | No | ||
| 10 | BAD | 1416582_a_at 1416583_at | 8347 | 0.154 | -0.2022 | No | ||
| 11 | PTEN | 1422553_at 1441593_at 1444325_at 1450655_at 1454722_at 1455728_at 1457493_at | 9442 | 0.123 | -0.2485 | No | ||
| 12 | YWHAZ | 1416102_at 1416103_at 1436971_x_at 1436981_a_at 1439005_x_at 1443893_at 1448218_s_at 1448219_a_at | 10068 | 0.106 | -0.2739 | No | ||
| 13 | YWHAQ | 1420828_s_at 1420829_a_at 1420830_x_at 1432842_s_at 1437608_x_at 1454378_at 1460590_s_at 1460621_x_at | 12435 | 0.048 | -0.3805 | No | ||
| 14 | SFN | 1448612_at | 14226 | -0.004 | -0.4621 | No | ||
| 15 | IGFBP1 | 1418918_at | 14760 | -0.023 | -0.4858 | No | ||
| 16 | IARS | 1426705_s_at 1452154_at | 15686 | -0.063 | -0.5261 | No | ||
| 17 | GSK3A | 1435638_at | 16002 | -0.081 | -0.5381 | No | ||
| 18 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 16083 | -0.086 | -0.5392 | No | ||
| 19 | SHC1 | 1422853_at 1422854_at | 16122 | -0.088 | -0.5383 | No | ||
| 20 | GRB2 | 1418508_a_at 1449111_a_at | 17171 | -0.170 | -0.5812 | No | ||
| 21 | AKT3 | 1422078_at 1435260_at 1435879_at 1443222_at 1460307_at | 17177 | -0.171 | -0.5764 | No | ||
| 22 | SOS2 | 1452281_at | 18613 | -0.379 | -0.6307 | No | ||
| 23 | DAPP1 | 1421936_at 1421937_at 1447337_at | 18854 | -0.431 | -0.6290 | No | ||
| 24 | SOS1 | 1421884_at 1421885_at 1421886_at | 18996 | -0.463 | -0.6217 | No | ||
| 25 | YWHAH | 1416004_at | 19192 | -0.509 | -0.6156 | No | ||
| 26 | RPS6KA3 | 1427299_at 1441360_at 1452383_at | 20099 | -0.804 | -0.6333 | Yes | ||
| 27 | INPP5D | 1418110_a_at 1424195_a_at | 20487 | -0.986 | -0.6219 | Yes | ||
| 28 | PDK1 | 1423747_a_at 1423748_at 1434974_at 1435836_at | 20815 | -1.229 | -0.6006 | Yes | ||
| 29 | PPP1R13B | 1434895_s_at 1442956_at 1459224_at | 21615 | -2.535 | -0.5623 | Yes | ||
| 30 | FOXO1A | 1416981_at 1416982_at 1416983_s_at 1459170_at | 21766 | -3.101 | -0.4777 | Yes | ||
| 31 | GSK3B | 1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at | 21811 | -3.432 | -0.3784 | Yes | ||
| 32 | AKT2 | 1421324_a_at 1424480_s_at 1455703_at | 21832 | -3.540 | -0.2749 | Yes | ||
| 33 | TEC | 1441524_at 1460204_at | 21881 | -4.130 | -0.1553 | Yes | ||
| 34 | YWHAE | 1426384_a_at 1426385_x_at 1435702_s_at 1438839_a_at 1440841_at 1457173_at | 21918 | -5.349 | 0.0008 | Yes |
