Details for gene set REACTOME_REGULATION_OF_INSULIN

Table: GSEA Results Summary

Dataset	Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos
Phenotype	phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos
Upregulated in class	ATM_minus
GeneSet	REACTOME_REGULATION_OF_INSULIN_SECRETION
Enrichment Score (ES)	0.6454742
Normalized Enrichment Score (NES)	2.0092995
Nominal p-value	0.0
FDR q-value	3.5E-4
FWER p-Value	0.0010

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	COX7C	1448112_at 1459884_at 1459885_s_at	0	8.097	0.0849	Yes
2	COX8A	1416112_at 1436409_at 1448222_x_at	2	6.931	0.1575	Yes
3	COX5B	1416902_a_at 1435613_x_at 1436149_at 1448514_at 1454716_x_at 1456588_x_at	3	6.855	0.2293	Yes
4	ATP5C1	1416058_s_at 1438809_at	15	5.347	0.2849	Yes
5	NDUFB8	1448198_a_at 1458404_at	46	4.285	0.3284	Yes
6	CYCS	1422484_at 1445484_at	51	4.211	0.3723	Yes
7	IDH3A	1422500_at 1422501_s_at 1432016_a_at 1447701_x_at	149	3.166	0.4011	Yes
8	PDHA1	1418560_at 1446954_at 1449137_at	150	3.164	0.4342	Yes
9	ATP5G1	1416020_a_at 1444874_at	224	2.845	0.4607	Yes
10	NDUFS8	1423907_a_at 1423908_at 1434212_at 1434213_x_at 1434579_x_at 1455283_x_at	419	2.164	0.4745	Yes
11	TPI1	1415918_a_at 1435659_a_at 1452927_x_at	606	1.765	0.4845	Yes
12	ATP5F1	1426742_at 1433562_s_at	759	1.576	0.4940	Yes
13	ETFA	1423972_at	974	1.326	0.4981	Yes
14	CS	1422577_at 1422578_at 1450667_a_at	987	1.312	0.5113	Yes
15	DLD	1423159_at	1314	1.077	0.5077	Yes
16	PKM2	1417308_at	1548	0.945	0.5069	Yes
17	NDUFV1	1415966_a_at 1415967_at 1456015_x_at	1579	0.931	0.5153	Yes
18	CYC1	1416604_at	1610	0.912	0.5235	Yes
19	NDUFC1	1416285_at 1448284_a_at	1678	0.889	0.5298	Yes
20	SDHD	1428235_at 1437489_x_at	1820	0.822	0.5319	Yes
21	ATP5L	1448203_at	1892	0.789	0.5369	Yes
22	UQCRFS1	1450968_at	1931	0.774	0.5433	Yes
23	NDUFS1	1425143_a_at 1453354_at	1983	0.753	0.5489	Yes
24	NDUFV2	1428179_at 1438159_x_at 1452692_a_at	2007	0.743	0.5556	Yes
25	UQCR	1448292_at	2018	0.740	0.5629	Yes
26	COX5A	1415933_a_at 1439267_x_at 1448153_at	2132	0.703	0.5651	Yes
27	ATP5J	1416143_at	2147	0.699	0.5718	Yes
28	NDUFB2	1416834_x_at 1442658_at 1448483_a_at 1453806_at	2158	0.695	0.5786	Yes
29	SDHB	1418005_at	2180	0.690	0.5849	Yes
30	NDUFS7	1424313_a_at 1451312_at	2206	0.681	0.5909	Yes
31	NDUFB10	1428322_a_at	2233	0.673	0.5967	Yes
32	SUCLG1	1415891_at	2329	0.642	0.5991	Yes
33	ETFB	1428181_at	2348	0.636	0.6049	Yes
34	PDHX	1456090_at 1459434_at	2352	0.636	0.6115	Yes
35	NDUFA8	1423692_at	2386	0.627	0.6165	Yes
36	GLP1R	1422330_at	2399	0.623	0.6225	Yes
37	NDUFA7	1422976_x_at 1428360_x_at 1436567_a_at 1450818_a_at 1455749_x_at	2532	0.589	0.6226	Yes
38	ATP5E	1416567_s_at	2817	0.525	0.6151	Yes
39	NDUFB6	1434056_a_at 1434057_at	2820	0.523	0.6205	Yes
40	NDUFB5	1417102_a_at 1448589_at	2896	0.508	0.6224	Yes
41	UQCRC1	1428782_a_at	2915	0.503	0.6268	Yes
42	IDH3G	1416788_a_at 1416789_at	2923	0.501	0.6318	Yes
43	NDUFA6	1448427_at	2965	0.493	0.6351	Yes
44	NDUFA5	1417285_a_at 1417286_at	2983	0.491	0.6394	Yes
45	ATP5O	1416278_a_at	3021	0.484	0.6428	Yes
46	NDUFS6	1433603_at	3153	0.461	0.6416	Yes
47	COX6C	1415970_at 1434491_a_at	3175	0.457	0.6455	Yes
48	NDUFS3	1423737_at	3333	0.434	0.6428	No
49	NDUFA9	1416663_at	3425	0.420	0.6431	No
50	UQCRC2	1428631_a_at 1435757_a_at	3584	0.400	0.6400	No
51	ADRA2A	1423022_at 1433600_at 1433601_at	3869	0.368	0.6309	No
52	ATP5A1	1420037_at 1423111_at 1449710_s_at	4020	0.352	0.6277	No
53	MDH2	1416478_a_at 1433984_a_at	4518	0.311	0.6082	No
54	ATP5B	1416829_at	4523	0.310	0.6112	No
55	COX6B1	1416565_at 1436757_a_at	4913	0.287	0.5964	No
56	SYT5	1422531_at	5042	0.281	0.5935	No
57	CHRM3	1422258_at	5163	0.275	0.5909	No
58	ATP5J2	1416269_at 1435395_s_at	5346	0.266	0.5853	No
59	ATP5I	1422525_at 1434053_x_at 1450640_x_at	5377	0.264	0.5867	No
60	PRKAR2B	1430640_a_at 1438664_at 1456475_s_at	5402	0.263	0.5884	No
61	DLAT	1426264_at 1426265_x_at 1452005_at	5622	0.253	0.5810	No
62	ABCC8	1455765_a_at 1457066_at	6152	0.229	0.5592	No
63	GNAS	1421740_at 1427789_s_at 1443007_at 1443375_at 1444767_at 1450186_s_at 1453413_at	6342	0.222	0.5528	No
64	NDUFS2	1451096_at	6654	0.210	0.5408	No
65	NDUFA1	1422241_a_at	8118	0.161	0.4755	No
66	UQCRQ	1427880_at 1430326_s_at 1437134_at 1452613_at	8694	0.144	0.4506	No
67	IQGAP1	1417379_at 1417380_at 1431395_a_at 1431396_at 1434998_at 1445724_at 1458124_at	8776	0.141	0.4484	No
68	ATP5D	1423716_s_at 1456580_s_at	8787	0.141	0.4494	No
69	NDUFB3	1416547_at	8967	0.136	0.4427	No
70	ATP5H	1423676_at 1435112_a_at	9029	0.135	0.4413	No
71	NDUFS5	1416494_at 1416495_s_at	9379	0.125	0.4266	No
72	GCG	1425952_a_at	9380	0.125	0.4279	No
73	NDUFA11	1429708_at 1444154_at	9455	0.123	0.4258	No
74	NDUFB7	1416417_a_at 1448331_at	9696	0.117	0.4160	No
75	KCNJ11	1450515_at 1455417_at	9834	0.112	0.4109	No
76	NDUFC2	1431670_at	10578	0.094	0.3779	No
77	COX6A1	1417417_a_at	10769	0.090	0.3701	No
78	PFKFB1	1427213_at	10817	0.088	0.3689	No
79	NDUFA10	1418068_at 1448934_at	11014	0.083	0.3608	No
80	NDUFB4	1428075_at 1428076_s_at 1432427_at	11038	0.082	0.3606	No
81	PFKFB3	1416432_at 1419882_at 1456676_a_at	11081	0.081	0.3595	No
82	AKAP5	1447301_at	11156	0.079	0.3570	No
83	COX4I1	1448322_a_at	11216	0.078	0.3551	No
84	NDUFA4	1424085_at	11719	0.065	0.3328	No
85	SDHA	1426688_at 1426689_s_at 1445317_at	12388	0.049	0.3027	No
86	PFKFB2	1422090_a_at 1422091_at 1422092_at 1429486_at 1431901_a_at	12946	0.034	0.2775	No
87	RAP1A	1424139_at	13497	0.019	0.2525	No
88	UQCRH	1452133_at 1453229_s_at	13504	0.019	0.2525	No
89	IDH3B	1418885_a_at 1418886_s_at 1441271_at	15101	-0.037	0.1797	No
90	NDUFA2	1417368_s_at	15514	-0.055	0.1614	No
91	PRKCA	1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at	15821	-0.071	0.1482	No
92	NDUFS4	1418117_at 1438166_x_at 1444464_at 1448959_at 1459760_at	15987	-0.080	0.1415	No
93	SLC2A2	1449067_at	16061	-0.085	0.1390	No
94	PDHB	1416090_at 1448214_at	17392	-0.196	0.0801	No
95	MARCKS	1415971_at 1415972_at 1430311_at 1437034_x_at 1456028_x_at	17459	-0.205	0.0793	No
96	PFKFB4	1456888_at	17655	-0.232	0.0728	No
97	ETFDH	1451084_at 1458152_at	17810	-0.253	0.0684	No
98	NDUFAB1	1428159_s_at 1428160_at 1435934_at 1447919_x_at 1453565_at 1458678_at	18725	-0.400	0.0307	No
99	COX7A2L	1421772_a_at 1432263_a_at 1432264_x_at	19458	-0.579	0.0032	No
100	NDUFA3	1428464_at 1430149_at 1452790_x_at	20225	-0.856	-0.0229	No
101	DLST	1423710_at 1430161_at 1431011_at 1437775_at	20847	-1.251	-0.0382	No
102	VAMP2	1420833_at 1420834_at	20961	-1.367	-0.0291	No
103	UQCRB	1416337_at 1455997_a_at	21131	-1.594	-0.0201	No
104	PRKACB	1420610_at 1420611_at 1457197_at	21429	-2.057	-0.0121	No
105	OGDH	1445632_at 1451274_at	21795	-3.369	0.0065	No