Details for gene set NUCLEAR

Table: GSEA Results Summary

Dataset	set04_transDMproB_versus_transDMpreB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	NUCLEAR_LUMEN
Enrichment Score (ES)	-0.5356465
Normalized Enrichment Score (NES)	-2.1094015
Nominal p-value	0.0
FDR q-value	4.7326204E-5
FWER p-Value	0.0010

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PPP1R9B	41	21.764	0.0180	No
2	HDAC7A	135	15.313	0.0271	No
3	GIT2	443	9.869	0.0195	No
4	ARNTL	459	9.736	0.0278	No
5	SMARCD2	502	9.325	0.0341	No
6	ISG20	507	9.256	0.0425	No
7	XRCC6	531	8.969	0.0496	No
8	MEN1	535	8.949	0.0577	No
9	PPARGC1A	584	8.495	0.0630	No
10	EPC1	657	7.949	0.0665	No
11	ERCC2	697	7.736	0.0715	No
12	WRN	1098	5.825	0.0551	No
13	SMAD4	1158	5.556	0.0571	No
14	SMARCA4	1203	5.422	0.0597	No
15	ATXN1	1217	5.372	0.0640	No
16	HDAC11	1331	5.017	0.0625	No
17	HCLS1	1375	4.905	0.0647	No
18	NAP1L3	1463	4.685	0.0643	No
19	ABL1	1628	4.243	0.0593	No
20	EZH2	1726	4.027	0.0577	No
21	PMF1	1794	3.870	0.0577	No
22	MYO6	1860	3.735	0.0576	No
23	ASF1A	2020	3.421	0.0521	No
24	PARP1	2106	3.254	0.0505	No
25	MDM2	2191	3.125	0.0488	No
26	INTS6	2210	3.096	0.0507	No
27	NFYB	2280	2.975	0.0497	No
28	RBPJ	2296	2.939	0.0516	No
29	SMARCD1	2302	2.929	0.0541	No
30	HIPK2	2305	2.926	0.0567	No
31	GTF3C5	2512	2.646	0.0479	No
32	HDAC1	2646	2.493	0.0430	No
33	NLRP5	2671	2.464	0.0440	No
34	NDUFA13	2679	2.452	0.0458	No
35	TOP2A	2867	2.266	0.0378	No
36	ELP4	2922	2.202	0.0369	No
37	NAP1L4	3595	1.689	0.0018	No
38	ATXN3	3644	1.660	0.0007	No
39	PAX8	3752	1.590	-0.0036	No
40	SAP30	3785	1.566	-0.0039	No
41	RBM39	3853	1.526	-0.0062	No
42	RPL11	3910	1.494	-0.0078	No
43	ZNF346	4047	1.417	-0.0139	No
44	RSF1	4056	1.411	-0.0130	No
45	RPS7	4096	1.385	-0.0139	No
46	HDAC5	4107	1.376	-0.0132	No
47	CCNT1	4108	1.376	-0.0119	No
48	NCOA6	4185	1.340	-0.0148	No
49	PITX2	4241	1.312	-0.0166	No
50	PTF1A	4259	1.305	-0.0163	No
51	SRP68	4612	1.140	-0.0344	No
52	NKX2-5	4641	1.126	-0.0349	No
53	SHFM1	4665	1.115	-0.0351	No
54	RELA	4669	1.113	-0.0342	No
55	SMAD2	4698	1.102	-0.0347	No
56	DDX11	4705	1.100	-0.0340	No
57	TAF7	4877	1.029	-0.0424	No
58	NAP1L2	4943	1.005	-0.0450	No
59	FOXE3	4949	1.003	-0.0444	No
60	CHMP1A	5013	0.976	-0.0469	No
61	MED12	5190	0.911	-0.0556	No
62	PHF12	5198	0.909	-0.0552	No
63	ZNF148	5406	0.827	-0.0657	No
64	FGF18	5489	0.797	-0.0694	No
65	TEP1	5641	0.733	-0.0770	No
66	POLA1	5762	0.693	-0.0829	No
67	HDAC3	5951	0.636	-0.0925	No
68	NOL4	5956	0.634	-0.0921	No
69	ZBTB16	6052	0.606	-0.0968	No
70	SPTBN4	6219	0.554	-0.1053	No
71	GLIS2	6289	0.534	-0.1086	No
72	RB1	6458	0.483	-0.1173	No
73	TAF13	7010	0.321	-0.1470	No
74	ING2	7020	0.319	-0.1472	No
75	NOL3	7142	0.283	-0.1535	No
76	GTF3C2	7650	0.132	-0.1810	No
77	RPL35	7675	0.126	-0.1822	No
78	DYRK1A	7838	0.077	-0.1910	No
79	HIF1A	7886	0.065	-0.1935	No
80	DEDD	8044	0.018	-0.2020	No
81	SMARCA5	8146	-0.008	-0.2075	No
82	HDAC6	8283	-0.050	-0.2149	No
83	ELF4	8385	-0.077	-0.2203	No
84	NFYA	8419	-0.085	-0.2221	No
85	GEMIN7	8619	-0.135	-0.2328	No
86	NCR1	8725	-0.162	-0.2384	No
87	EPAS1	8868	-0.195	-0.2459	No
88	EXOSC9	9190	-0.274	-0.2632	No
89	ELL2	9311	-0.306	-0.2694	No
90	XPO1	9351	-0.313	-0.2712	No
91	TOP1	9529	-0.354	-0.2806	No
92	CENPF	9613	-0.374	-0.2847	No
93	ZNF638	9721	-0.402	-0.2902	No
94	TOPBP1	9813	-0.426	-0.2948	No
95	SMARCB1	9881	-0.447	-0.2980	No
96	NUFIP1	10054	-0.493	-0.3069	No
97	DEDD2	10058	-0.494	-0.3066	No
98	NEK11	10101	-0.503	-0.3084	No
99	TFIP11	10197	-0.527	-0.3131	No
100	PHF21A	10391	-0.579	-0.3231	No
101	PHB	10585	-0.623	-0.3331	No
102	HDAC8	10616	-0.631	-0.3341	No
103	SAP18	10637	-0.636	-0.3346	No
104	FIGLA	10646	-0.638	-0.3345	No
105	HDAC9	10695	-0.647	-0.3365	No
106	OIP5	10865	-0.687	-0.3450	No
107	CPSF3	10994	-0.714	-0.3514	No
108	POLR2B	11131	-0.747	-0.3581	No
109	DNAJB9	11319	-0.792	-0.3675	No
110	TOP2B	11409	-0.816	-0.3716	No
111	RTCD1	11683	-0.887	-0.3857	No
112	GCM1	11831	-0.925	-0.3928	No
113	HMGA1	11904	-0.945	-0.3959	No
114	MORF4L2	12013	-0.973	-0.4009	No
115	TAF6L	12096	-0.997	-0.4044	No
116	ARID4A	12109	-1.000	-0.4041	No
117	SFRS2IP	12157	-1.014	-0.4058	No
118	POLR3K	12184	-1.020	-0.4062	No
119	NFYC	12241	-1.035	-0.4083	No
120	KIN	12253	-1.039	-0.4080	No
121	KLHL7	12325	-1.058	-0.4108	No
122	FMR1	12490	-1.106	-0.4188	No
123	PRM2	12524	-1.114	-0.4195	No
124	TP53	12667	-1.162	-0.4262	No
125	OGG1	12730	-1.180	-0.4285	No
126	NPM1	12806	-1.199	-0.4314	No
127	DDX56	12810	-1.201	-0.4305	No
128	HDAC2	12814	-1.204	-0.4295	No
129	RPA1	12898	-1.231	-0.4329	No
130	NF2	12930	-1.238	-0.4335	No
131	MPHOSPH10	12987	-1.259	-0.4353	No
132	APTX	13229	-1.332	-0.4472	No
133	THRAP3	13240	-1.335	-0.4465	No
134	EMG1	13304	-1.355	-0.4487	No
135	HTATIP	13378	-1.381	-0.4514	No
136	POLH	13560	-1.445	-0.4599	No
137	GTF3C1	13603	-1.460	-0.4609	No
138	IFI16	13616	-1.464	-0.4602	No
139	ILF2	13672	-1.480	-0.4618	No
140	CBX1	13791	-1.523	-0.4668	No
141	BNIP3	13848	-1.550	-0.4684	No
142	EXOSC10	14142	-1.657	-0.4829	No
143	EDF1	14151	-1.661	-0.4818	No
144	TAF9	14194	-1.675	-0.4825	No
145	TAF4	14215	-1.684	-0.4820	No
146	DDX24	14275	-1.707	-0.4836	No
147	RBBP5	14388	-1.758	-0.4881	No
148	MPHOSPH1	14392	-1.760	-0.4867	No
149	RPL3	14414	-1.768	-0.4862	No
150	NUP98	14448	-1.788	-0.4863	No
151	ARID1A	14510	-1.815	-0.4879	No
152	RPL36	14541	-1.830	-0.4879	No
153	NPAS2	14628	-1.866	-0.4908	No
154	ACTB	14646	-1.876	-0.4900	No
155	ACTL6A	14692	-1.896	-0.4907	No
156	POLR3C	14699	-1.900	-0.4893	No
157	CHAF1A	14749	-1.922	-0.4902	No
158	SMC3	14841	-1.964	-0.4933	No
159	DNMT3A	15077	-2.085	-0.5042	No
160	UBE2I	15145	-2.132	-0.5058	No
161	NUDT21	15254	-2.189	-0.5097	No
162	KPNA2	15374	-2.266	-0.5141	No
163	LRCH4	15409	-2.286	-0.5138	No
164	SP100	15446	-2.317	-0.5136	No
165	ERCC5	15513	-2.361	-0.5150	No
166	SMUG1	15526	-2.370	-0.5135	No
167	PTBP1	15547	-2.383	-0.5124	No
168	SMARCD3	15609	-2.423	-0.5134	No
169	RBM14	15645	-2.451	-0.5131	No
170	TAF6	15743	-2.531	-0.5160	No
171	TOPORS	15783	-2.568	-0.5157	No
172	TAF10	15882	-2.663	-0.5186	No
173	TCOF1	15923	-2.708	-0.5183	No
174	TDG	16099	-2.868	-0.5252	No
175	ASH2L	16172	-2.943	-0.5263	No
176	TAF11	16185	-2.954	-0.5243	No
177	PML	16395	-3.157	-0.5327	Yes
178	RPS19	16427	-3.203	-0.5314	Yes
179	TAF5	16440	-3.220	-0.5291	Yes
180	UBTF	16478	-3.280	-0.5281	Yes
181	MED6	16493	-3.299	-0.5258	Yes
182	MCM7	16549	-3.369	-0.5256	Yes
183	POLQ	16559	-3.379	-0.5230	Yes
184	RPP40	16636	-3.509	-0.5239	Yes
185	CDK9	16670	-3.556	-0.5224	Yes
186	ASNA1	16701	-3.604	-0.5207	Yes
187	DDX54	16703	-3.608	-0.5174	Yes
188	FOXF2	16743	-3.668	-0.5161	Yes
189	POLR2A	16745	-3.671	-0.5127	Yes
190	SNAPC4	16751	-3.672	-0.5096	Yes
191	HES6	16773	-3.725	-0.5073	Yes
192	CHAF1B	16800	-3.764	-0.5052	Yes
193	PRPF31	16804	-3.767	-0.5019	Yes
194	NR6A1	16824	-3.805	-0.4994	Yes
195	SLC29A2	16830	-3.812	-0.4961	Yes
196	ERCC3	16844	-3.832	-0.4933	Yes
197	POLI	16918	-3.949	-0.4936	Yes
198	MED4	16993	-4.084	-0.4938	Yes
199	SMARCC1	16998	-4.102	-0.4902	Yes
200	GTF2F1	17026	-4.152	-0.4878	Yes
201	ELP3	17059	-4.226	-0.4857	Yes
202	EED	17079	-4.262	-0.4827	Yes
203	MCRS1	17108	-4.328	-0.4803	Yes
204	HNRPK	17113	-4.353	-0.4764	Yes
205	TBP	17173	-4.481	-0.4755	Yes
206	NCL	17298	-4.766	-0.4778	Yes
207	CPSF1	17324	-4.825	-0.4747	Yes
208	MRE11A	17329	-4.842	-0.4704	Yes
209	POP7	17342	-4.876	-0.4666	Yes
210	CHEK2	17344	-4.882	-0.4621	Yes
211	TIMM50	17381	-4.986	-0.4594	Yes
212	CLOCK	17406	-5.039	-0.4560	Yes
213	GTF3C4	17454	-5.193	-0.4538	Yes
214	GTF2H1	17462	-5.217	-0.4493	Yes
215	RPP30	17466	-5.232	-0.4446	Yes
216	GTF3C3	17522	-5.387	-0.4426	Yes
217	WDR4	17546	-5.484	-0.4388	Yes
218	POP1	17568	-5.551	-0.4348	Yes
219	SURF6	17585	-5.588	-0.4305	Yes
220	NARG1	17598	-5.625	-0.4259	Yes
221	SFRS2	17611	-5.660	-0.4213	Yes
222	SMARCE1	17659	-5.826	-0.4184	Yes
223	GEMIN4	17708	-6.053	-0.4154	Yes
224	YEATS4	17716	-6.084	-0.4102	Yes
225	TRIM27	17724	-6.108	-0.4049	Yes
226	IVNS1ABP	17729	-6.121	-0.3994	Yes
227	LMO4	17762	-6.261	-0.3954	Yes
228	POLR2E	17780	-6.378	-0.3904	Yes
229	NOLA3	17789	-6.418	-0.3848	Yes
230	TAF12	17838	-6.593	-0.3813	Yes
231	POLR2J	17854	-6.637	-0.3760	Yes
232	NUP54	17873	-6.727	-0.3707	Yes
233	CIB1	17893	-6.840	-0.3654	Yes
234	COIL	17903	-6.900	-0.3595	Yes
235	PPARGC1B	17931	-7.029	-0.3544	Yes
236	KRR1	17935	-7.045	-0.3481	Yes
237	NAP1L1	17964	-7.211	-0.3429	Yes
238	NSUN2	17980	-7.272	-0.3370	Yes
239	RUVBL2	18004	-7.399	-0.3313	Yes
240	FUSIP1	18008	-7.442	-0.3246	Yes
241	CDK8	18025	-7.534	-0.3185	Yes
242	MPG	18063	-7.816	-0.3132	Yes
243	U2AF1	18107	-7.981	-0.3082	Yes
244	RUVBL1	18140	-8.166	-0.3023	Yes
245	GEMIN5	18157	-8.278	-0.2955	Yes
246	DDX47	18169	-8.347	-0.2884	Yes
247	EXOSC1	18195	-8.515	-0.2818	Yes
248	HDAC10	18249	-9.001	-0.2764	Yes
249	RPP38	18292	-9.374	-0.2699	Yes
250	NOLC1	18312	-9.599	-0.2621	Yes
251	ERCC8	18321	-9.658	-0.2535	Yes
252	GEMIN6	18351	-9.900	-0.2459	Yes
253	DDX21	18358	-9.939	-0.2370	Yes
254	GTF2H4	18376	-10.219	-0.2285	Yes
255	LYAR	18381	-10.278	-0.2191	Yes
256	POLR3H	18389	-10.361	-0.2099	Yes
257	NOL5A	18411	-10.638	-0.2012	Yes
258	MKI67IP	18417	-10.776	-0.1914	Yes
259	GNL3	18452	-11.263	-0.1828	Yes
260	XRN2	18470	-11.662	-0.1729	Yes
261	WDHD1	18476	-11.829	-0.1622	Yes
262	IKBKAP	18482	-12.034	-0.1513	Yes
263	SDAD1	18489	-12.180	-0.1404	Yes
264	MYBBP1A	18528	-13.465	-0.1299	Yes
265	CIRH1A	18544	-14.093	-0.1177	Yes
266	POLR1E	18551	-14.479	-0.1045	Yes
267	NOLA2	18553	-14.693	-0.0910	Yes
268	NOL6	18555	-14.865	-0.0772	Yes
269	RRP9	18558	-15.044	-0.0634	Yes
270	NOL1	18564	-15.630	-0.0491	Yes
271	CDKN2A	18616	-55.900	0.0000	Yes