Datasetset04_transDMproB_versus_transDMpreB
PhenotypeNoPhenotypeAvailable
Upregulated in classna_neg
GeneSetREACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS
Enrichment Score (ES)-0.7759383
Normalized Enrichment Score (NES)-2.1220987
Nominal p-value0.0
FDR q-value1.8095606E-4
FWER p-Value0.0030
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CDC25C20823.290-0.0839No
2RPA112898-1.231-0.6552No
3RAD114121-1.648-0.7068No
4MCM614599-1.854-0.7167No
5MCM515314-2.227-0.7361No
6CHEK116056-2.832-0.7518Yes
7CDC716081-2.853-0.7287Yes
8MCM216404-3.166-0.7190Yes
9ORC4L16414-3.183-0.6924Yes
10RFC316431-3.206-0.6659Yes
11MCM716549-3.369-0.6434Yes
12RPA316606-3.458-0.6170Yes
13MCM416623-3.480-0.5881Yes
14CDK216879-3.891-0.5687Yes
15MCM316907-3.932-0.5366Yes
16CDC25A17396-5.014-0.5200Yes
17HUS117418-5.066-0.4779Yes
18RPA217511-5.355-0.4372Yes
19CDC45L17635-5.759-0.3947Yes
20RAD9B17704-6.020-0.3470Yes
21ORC2L17822-6.535-0.2975Yes
22MCM1017841-6.601-0.2422Yes
23ORC1L17868-6.700-0.1864Yes
24RFC517910-6.942-0.1294Yes
25RFC418000-7.383-0.0712Yes
26ORC5L18491-12.2270.0067Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS: Random ES distribution   
Gene set null distribution of ES for REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS