Details for gene set DNA_METABOLIC

Table: GSEA Results Summary

Dataset	set04_transDMproB_versus_LMproB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	DNA_METABOLIC_PROCESS
Enrichment Score (ES)	-0.3958903
Normalized Enrichment Score (NES)	-1.851916
Nominal p-value	0.0
FDR q-value	0.058564242
FWER p-Value	0.656

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MSH5	154	3.949	0.0027	No
2	LIG4	157	3.931	0.0137	No
3	ATF7IP	172	3.836	0.0238	No
4	XRCC4	183	3.781	0.0339	No
5	TFAM	205	3.716	0.0432	No
6	RAG1	266	3.461	0.0497	No
7	UBE2A	291	3.364	0.0578	No
8	SMARCAD1	599	2.728	0.0488	No
9	TERF2IP	615	2.705	0.0556	No
10	CDKN2A	661	2.646	0.0606	No
11	SUMO1	775	2.511	0.0616	No
12	KPNA1	873	2.402	0.0630	No
13	CDKN2D	886	2.387	0.0691	No
14	ORC5L	957	2.331	0.0719	No
15	RPA3	961	2.327	0.0783	No
16	CIB1	1035	2.268	0.0807	No
17	ERCC8	1068	2.247	0.0853	No
18	KPNA2	1136	2.200	0.0878	No
19	S100A11	1172	2.177	0.0921	No
20	UBE2N	1355	2.064	0.0880	No
21	PTGES3	1432	2.013	0.0895	No
22	TINF2	1452	1.995	0.0941	No
23	IGF1	1567	1.934	0.0933	No
24	CYCS	1680	1.874	0.0925	No
25	MSH6	1681	1.874	0.0978	No
26	DDB1	1819	1.814	0.0955	No
27	REPIN1	1908	1.767	0.0957	No
28	ASF1A	2000	1.725	0.0956	No
29	TIPIN	2131	1.671	0.0932	No
30	CIDEA	2325	1.604	0.0872	No
31	ERCC4	2329	1.602	0.0916	No
32	ATXN3	2565	1.526	0.0831	No
33	POLD4	2599	1.516	0.0856	No
34	RAD21	2736	1.470	0.0823	No
35	RAD51L1	2761	1.459	0.0851	No
36	PNKP	2959	1.394	0.0783	No
37	RAD17	3013	1.378	0.0793	No
38	HMGB2	3135	1.340	0.0765	No
39	XRN2	3203	1.316	0.0766	No
40	TBRG1	3355	1.273	0.0720	No
41	SMARCAL1	3437	1.246	0.0711	No
42	GMNN	3548	1.209	0.0685	No
43	ATM	3638	1.186	0.0670	No
44	GADD45G	3647	1.183	0.0699	No
45	ADRA1D	3725	1.162	0.0690	No
46	MNAT1	3798	1.143	0.0683	No
47	UBE2B	3808	1.138	0.0710	No
48	MSH3	3824	1.135	0.0734	No
49	DNMT3A	4030	1.088	0.0653	No
50	FANCC	4074	1.077	0.0660	No
51	IGFBP4	4146	1.059	0.0651	No
52	MYST2	4392	1.005	0.0546	No
53	XRCC5	4569	0.965	0.0478	No
54	MCM3AP	4637	0.950	0.0468	No
55	RFC4	4891	0.894	0.0356	No
56	MUTYH	4986	0.875	0.0329	No
57	SMUG1	5191	0.835	0.0242	No
58	TPD52L1	5206	0.832	0.0258	No
59	GADD45A	5285	0.815	0.0238	No
60	XRCC6	5288	0.814	0.0260	No
61	HMGB1	5302	0.811	0.0276	No
62	APTX	5422	0.784	0.0233	No
63	MCM3	5720	0.721	0.0092	No
64	KCTD13	5733	0.717	0.0106	No
65	BTG2	5861	0.692	0.0056	No
66	FEN1	5919	0.680	0.0044	No
67	POLB	6021	0.661	0.0008	No
68	BNIP3	6288	0.613	-0.0119	No
69	TREX2	6406	0.590	-0.0166	No
70	SOD1	6486	0.576	-0.0193	No
71	CHEK1	6785	0.522	-0.0340	No
72	ORC3L	7143	0.446	-0.0522	No
73	RAN	7264	0.422	-0.0575	No
74	XRCC2	7529	0.380	-0.0708	No
75	POLA1	7588	0.368	-0.0729	No
76	MPG	7665	0.353	-0.0760	No
77	RAD23B	7714	0.344	-0.0777	No
78	RUVBL2	7879	0.315	-0.0857	No
79	ALKBH1	7924	0.307	-0.0872	No
80	DNASE2	8031	0.284	-0.0922	No
81	POT1	8070	0.279	-0.0935	No
82	RAD1	8160	0.265	-0.0976	No
83	GLI2	8173	0.262	-0.0975	No
84	TERF2	8216	0.255	-0.0991	No
85	ORC4L	8236	0.251	-0.0994	No
86	FANCA	8327	0.235	-0.1036	No
87	HUS1	8335	0.234	-0.1033	No
88	RFC3	8392	0.226	-0.1057	No
89	PMS1	8867	0.140	-0.1311	No
90	PPARGC1A	9438	0.044	-0.1620	No
91	NF2	9447	0.043	-0.1623	No
92	PMS2	9581	0.014	-0.1695	No
93	TERT	9808	-0.031	-0.1817	No
94	ACHE	9912	-0.052	-0.1871	No
95	SETMAR	9963	-0.060	-0.1897	No
96	GTPBP4	10001	-0.067	-0.1915	No
97	CD40LG	10165	-0.096	-0.2001	No
98	HTATIP	10286	-0.118	-0.2063	No
99	IL4	10370	-0.134	-0.2104	No
100	TNP1	10389	-0.138	-0.2110	No
101	MCM7	10535	-0.166	-0.2184	No
102	ISG20	10622	-0.179	-0.2226	No
103	IGHMBP2	10770	-0.205	-0.2300	No
104	ATR	10794	-0.209	-0.2307	No
105	NUP98	10868	-0.224	-0.2340	No
106	MCM2	11019	-0.249	-0.2415	No
107	RNASEH2A	11053	-0.255	-0.2426	No
108	TLK2	11212	-0.291	-0.2503	No
109	XRCC3	11389	-0.323	-0.2590	No
110	POLH	11578	-0.358	-0.2682	No
111	PRIM1	11609	-0.365	-0.2688	No
112	XAB2	11617	-0.367	-0.2681	No
113	CECR2	11696	-0.386	-0.2713	No
114	REV3L	11777	-0.400	-0.2745	No
115	AIFM1	11842	-0.414	-0.2768	No
116	SYCP1	11925	-0.429	-0.2801	No
117	POLE2	11991	-0.438	-0.2824	No
118	TOP2A	12133	-0.467	-0.2887	No
119	REV1	12154	-0.471	-0.2885	No
120	ORC2L	12416	-0.522	-0.3012	No
121	SMG6	12507	-0.540	-0.3046	No
122	RAD51C	12872	-0.613	-0.3227	No
123	CDC6	12983	-0.636	-0.3268	No
124	EGF	13134	-0.666	-0.3331	No
125	POLG	13179	-0.677	-0.3336	No
126	TGFB1	13308	-0.704	-0.3386	No
127	GLI1	13401	-0.726	-0.3415	No
128	UBE2V2	13435	-0.732	-0.3413	No
129	EXO1	13747	-0.808	-0.3559	No
130	HELLS	13962	-0.857	-0.3651	No
131	TNFSF13	14078	-0.889	-0.3689	No
132	MSH2	14083	-0.890	-0.3666	No
133	RBMS1	14088	-0.891	-0.3643	No
134	SUPV3L1	14104	-0.893	-0.3626	No
135	ERCC3	14137	-0.903	-0.3618	No
136	TSN	14159	-0.909	-0.3604	No
137	ATRX	14216	-0.923	-0.3608	No
138	WRNIP1	14346	-0.959	-0.3651	No
139	MGMT	14355	-0.963	-0.3629	No
140	POLD2	14522	-1.009	-0.3690	No
141	SET	14538	-1.013	-0.3670	No
142	FOXL2	14558	-1.018	-0.3652	No
143	MSH4	14673	-1.045	-0.3684	No
144	ORC1L	14735	-1.063	-0.3687	No
145	GTF2H4	14739	-1.064	-0.3659	No
146	DMC1	14768	-1.072	-0.3644	No
147	RAD23A	14873	-1.100	-0.3670	No
148	RECQL	15123	-1.171	-0.3772	No
149	RAD51L3	15159	-1.181	-0.3758	No
150	FANCG	15268	-1.211	-0.3783	No
151	DFFB	15298	-1.219	-0.3764	No
152	POLL	15358	-1.239	-0.3761	No
153	DNMT3B	15431	-1.268	-0.3765	No
154	PURA	15510	-1.289	-0.3771	No
155	CDC45L	15791	-1.386	-0.3884	No
156	OGG1	15818	-1.398	-0.3859	No
157	BRCA1	15837	-1.405	-0.3829	No
158	RAD52	15985	-1.464	-0.3868	No
159	NTHL1	16154	-1.533	-0.3916	Yes
160	NAP1L1	16172	-1.539	-0.3882	Yes
161	CSNK1D	16188	-1.547	-0.3846	Yes
162	POLG2	16189	-1.547	-0.3803	Yes
163	UNG	16214	-1.554	-0.3772	Yes
164	CDK2	16312	-1.588	-0.3780	Yes
165	SMARCB1	16313	-1.589	-0.3735	Yes
166	BRCA2	16426	-1.645	-0.3750	Yes
167	POLQ	16523	-1.692	-0.3754	Yes
168	TDG	16589	-1.718	-0.3741	Yes
169	ERCC1	16754	-1.814	-0.3779	Yes
170	RAD51	16891	-1.889	-0.3800	Yes
171	DFFA	16914	-1.903	-0.3758	Yes
172	TEP1	16937	-1.917	-0.3716	Yes
173	KIN	17024	-1.968	-0.3708	Yes
174	POLE3	17042	-1.992	-0.3661	Yes
175	POLE	17055	-2.001	-0.3611	Yes
176	FOS	17081	-2.016	-0.3568	Yes
177	RPA1	17200	-2.124	-0.3572	Yes
178	BLM	17210	-2.133	-0.3517	Yes
179	MRE11A	17211	-2.133	-0.3457	Yes
180	EREG	17216	-2.137	-0.3399	Yes
181	RECQL5	17311	-2.213	-0.3388	Yes
182	NT5M	17365	-2.259	-0.3353	Yes
183	LIG1	17428	-2.306	-0.3322	Yes
184	NASP	17437	-2.319	-0.3261	Yes
185	RAD9A	17496	-2.372	-0.3225	Yes
186	UPF1	17640	-2.521	-0.3232	Yes
187	LIG3	17653	-2.540	-0.3167	Yes
188	ERCC2	17660	-2.555	-0.3099	Yes
189	DDB2	17719	-2.609	-0.3057	Yes
190	CDK2AP1	17730	-2.620	-0.2988	Yes
191	GTF2H1	17736	-2.627	-0.2917	Yes
192	APEX1	17738	-2.629	-0.2844	Yes
193	DNMT1	17892	-2.816	-0.2847	Yes
194	MCM5	17916	-2.853	-0.2780	Yes
195	RAD50	17930	-2.875	-0.2706	Yes
196	POLI	17938	-2.884	-0.2628	Yes
197	IL7R	17965	-2.931	-0.2560	Yes
198	TLK1	17972	-2.941	-0.2480	Yes
199	NBN	17973	-2.942	-0.2397	Yes
200	POLK	17979	-2.950	-0.2317	Yes
201	MLH1	17987	-2.959	-0.2238	Yes
202	CDT1	18056	-3.044	-0.2189	Yes
203	PPT1	18057	-3.044	-0.2103	Yes
204	SPO11	18067	-3.063	-0.2022	Yes
205	ABL1	18084	-3.088	-0.1943	Yes
206	NT5E	18123	-3.158	-0.1875	Yes
207	XPC	18146	-3.203	-0.1797	Yes
208	UBE2V1	18169	-3.244	-0.1717	Yes
209	DMAP1	18182	-3.268	-0.1632	Yes
210	ERCC5	18295	-3.572	-0.1592	Yes
211	RFC1	18319	-3.654	-0.1502	Yes
212	VCP	18328	-3.709	-0.1402	Yes
213	RECQL4	18340	-3.739	-0.1302	Yes
214	SMC1A	18351	-3.769	-0.1202	Yes
215	PICK1	18358	-3.793	-0.1098	Yes
216	PARP1	18383	-3.892	-0.1002	Yes
217	RAD54L	18448	-4.193	-0.0918	Yes
218	CSNK1E	18481	-4.377	-0.0812	Yes
219	NP	18491	-4.440	-0.0692	Yes
220	RPA2	18496	-4.505	-0.0568	Yes
221	BAX	18573	-5.849	-0.0444	Yes
222	POLD1	18575	-5.904	-0.0278	Yes
223	TP53	18610	-10.661	0.0003	Yes