Details for gene set HSA04530_TIGHT

Table: GSEA Results Summary

Dataset	set04_transDMproB_versus_LMproB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	HSA04530_TIGHT_JUNCTION
Enrichment Score (ES)	-0.4210759
Normalized Enrichment Score (NES)	-1.760086
Nominal p-value	0.0
FDR q-value	0.33104956
FWER p-Value	0.722

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MYL2	425	3.024	-0.0038	No
2	RRAS	451	2.973	0.0137	No
3	CDC42	507	2.885	0.0291	No
4	MYLPF	672	2.637	0.0369	No
5	MYL9	679	2.624	0.0532	No
6	JAM2	1795	1.825	0.0046	No
7	PPP2R4	1846	1.802	0.0133	No
8	CLDN4	1854	1.799	0.0243	No
9	PTEN	1917	1.762	0.0322	No
10	MYH11	1956	1.745	0.0412	No
11	VAPA	2441	1.565	0.0250	No
12	ACTG1	2500	1.546	0.0316	No
13	EXOC3	2600	1.516	0.0359	No
14	PARD6A	3149	1.333	0.0148	No
15	CLDN1	3343	1.280	0.0124	No
16	AKT3	3346	1.278	0.0204	No
17	RAB13	4047	1.083	-0.0105	No
18	MYL7	4160	1.056	-0.0098	No
19	MYH2	4197	1.048	-0.0051	No
20	CSNK2A1	4357	1.014	-0.0073	No
21	CRB3	4630	0.952	-0.0159	No
22	PRKCZ	4634	0.951	-0.0101	No
23	CLDN9	4742	0.926	-0.0100	No
24	CLDN23	5092	0.855	-0.0234	No
25	CLDN19	5199	0.833	-0.0239	No
26	RHOA	5246	0.824	-0.0211	No
27	PARD6B	5531	0.762	-0.0316	No
28	PPP2CB	5920	0.679	-0.0483	No
29	F11R	6097	0.647	-0.0537	No
30	JAM3	6595	0.557	-0.0770	No
31	PPP2R2A	6596	0.557	-0.0734	No
32	PARD6G	6787	0.521	-0.0804	No
33	PRKCI	7099	0.456	-0.0943	No
34	CLDN5	7136	0.448	-0.0934	No
35	MPDZ	7186	0.438	-0.0933	No
36	PRKCQ	7521	0.381	-0.1089	No
37	CLDN11	7537	0.378	-0.1073	No
38	MRAS	7722	0.343	-0.1151	No
39	PPP2R1A	7811	0.328	-0.1177	No
40	SRC	8170	0.263	-0.1354	No
41	HRAS	8277	0.244	-0.1396	No
42	CLDN8	8743	0.162	-0.1637	No
43	PRKCE	8821	0.148	-0.1669	No
44	MYH3	8978	0.121	-0.1745	No
45	MYH6	9651	-0.000	-0.2108	No
46	NRAS	9797	-0.029	-0.2185	No
47	CSNK2B	10022	-0.070	-0.2301	No
48	GNAI1	10182	-0.098	-0.2381	No
49	AKT1	10228	-0.108	-0.2398	No
50	PPP2CA	11227	-0.293	-0.2918	No
51	RAB3B	12039	-0.449	-0.3328	No
52	KRAS	12215	-0.484	-0.3392	No
53	CLDN16	12312	-0.503	-0.3412	No
54	ASH1L	12333	-0.507	-0.3390	No
55	MYH4	12401	-0.518	-0.3394	No
56	CLDN2	12534	-0.546	-0.3430	No
57	GNAI3	13072	-0.655	-0.3679	No
58	PRKCB1	13209	-0.683	-0.3709	No
59	CASK	13474	-0.741	-0.3804	No
60	ACTB	13575	-0.764	-0.3810	No
61	CLDN14	13582	-0.766	-0.3765	No
62	RRAS2	13667	-0.786	-0.3760	No
63	CLDN17	13834	-0.827	-0.3797	No
64	CLDN18	14187	-0.917	-0.3929	No
65	CLDN7	14327	-0.953	-0.3944	No
66	MYH14	14743	-1.065	-0.4101	No
67	CLDN15	14871	-1.100	-0.4099	No
68	OCLN	14990	-1.132	-0.4091	No
69	PARD3	15024	-1.142	-0.4037	No
70	YES1	15065	-1.152	-0.3985	No
71	CGN	15265	-1.209	-0.4016	No
72	CTTN	15525	-1.293	-0.4074	No
73	TJP1	15639	-1.335	-0.4050	No
74	AKT2	15689	-1.350	-0.3991	No
75	ACTN2	15894	-1.429	-0.4011	No
76	CDK4	16191	-1.548	-0.4073	No
77	CLDN10	16448	-1.657	-0.4106	Yes
78	MYH7	16454	-1.658	-0.4003	Yes
79	PRKCA	16510	-1.682	-0.3926	Yes
80	ACTN3	16938	-1.917	-0.4035	Yes
81	CLDN3	16951	-1.928	-0.3920	Yes
82	PRKCD	16955	-1.929	-0.3799	Yes
83	CSDA	17360	-2.253	-0.3874	Yes
84	MPP5	17603	-2.490	-0.3847	Yes
85	MYH9	17671	-2.566	-0.3720	Yes
86	PRKCH	17677	-2.572	-0.3560	Yes
87	PPM1J	17684	-2.577	-0.3400	Yes
88	ACTN4	17813	-2.730	-0.3296	Yes
89	MAGI1	17814	-2.731	-0.3123	Yes
90	TJP2	18156	-3.212	-0.3103	Yes
91	TJP3	18202	-3.319	-0.2917	Yes
92	INADL	18311	-3.624	-0.2746	Yes
93	HCLS1	18326	-3.704	-0.2518	Yes
94	CSNK2A2	18390	-3.916	-0.2304	Yes
95	EXOC4	18563	-5.605	-0.2042	Yes
96	MYH10	18593	-7.046	-0.1611	Yes
97	MYLC2PL	18611	-10.977	-0.0924	Yes
98	AMOTL1	18615	-14.604	0.0001	Yes