Dataset | set04_transDMproB_versus_DMpreB |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_pos |
GeneSet | PROTEIN_KINASE_CASCADE |
Enrichment Score (ES) | 0.45997843 |
Normalized Enrichment Score (NES) | 1.7580036 |
Nominal p-value | 0.0 |
FDR q-value | 0.17255132 |
FWER p-Value | 0.879 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | STAT4 | 7 | 37.571 | 0.0424 | Yes | ||
2 | CD27 | 142 | 15.671 | 0.0529 | Yes | ||
3 | EDG5 | 146 | 15.468 | 0.0703 | Yes | ||
4 | CD81 | 172 | 14.492 | 0.0855 | Yes | ||
5 | TSPAN6 | 194 | 14.071 | 0.1003 | Yes | ||
6 | IFNAR2 | 256 | 12.952 | 0.1118 | Yes | ||
7 | MAPKAPK2 | 276 | 12.560 | 0.1250 | Yes | ||
8 | SQSTM1 | 358 | 11.554 | 0.1338 | Yes | ||
9 | STAT1 | 359 | 11.544 | 0.1469 | Yes | ||
10 | MAP3K11 | 373 | 11.326 | 0.1591 | Yes | ||
11 | DUSP6 | 429 | 10.680 | 0.1682 | Yes | ||
12 | SOCS2 | 459 | 10.367 | 0.1785 | Yes | ||
13 | TNFRSF1A | 483 | 10.110 | 0.1887 | Yes | ||
14 | MAP3K3 | 488 | 10.054 | 0.1999 | Yes | ||
15 | STAT3 | 490 | 10.026 | 0.2113 | Yes | ||
16 | TNFSF10 | 532 | 9.625 | 0.2200 | Yes | ||
17 | FYN | 553 | 9.371 | 0.2296 | Yes | ||
18 | MAPK9 | 558 | 9.321 | 0.2400 | Yes | ||
19 | LGALS9 | 579 | 9.195 | 0.2493 | Yes | ||
20 | MAP3K7IP2 | 630 | 8.758 | 0.2566 | Yes | ||
21 | PINK1 | 646 | 8.629 | 0.2656 | Yes | ||
22 | RPS6KA4 | 647 | 8.625 | 0.2754 | Yes | ||
23 | TNFAIP3 | 654 | 8.578 | 0.2848 | Yes | ||
24 | WNK1 | 664 | 8.522 | 0.2941 | Yes | ||
25 | MAP4K2 | 708 | 8.299 | 0.3012 | Yes | ||
26 | NOD1 | 741 | 8.108 | 0.3086 | Yes | ||
27 | LITAF | 745 | 8.089 | 0.3177 | Yes | ||
28 | IL12A | 753 | 8.069 | 0.3265 | Yes | ||
29 | MAPK14 | 754 | 8.054 | 0.3356 | Yes | ||
30 | STAT5A | 807 | 7.710 | 0.3416 | Yes | ||
31 | MAP3K5 | 939 | 7.023 | 0.3425 | Yes | ||
32 | CASP8 | 989 | 6.782 | 0.3475 | Yes | ||
33 | IKBKG | 992 | 6.767 | 0.3551 | Yes | ||
34 | MAP4K3 | 1137 | 6.199 | 0.3543 | Yes | ||
35 | RPS6KA2 | 1164 | 6.074 | 0.3598 | Yes | ||
36 | HCLS1 | 1234 | 5.791 | 0.3626 | Yes | ||
37 | TBK1 | 1237 | 5.784 | 0.3691 | Yes | ||
38 | RIPK1 | 1256 | 5.685 | 0.3746 | Yes | ||
39 | LGALS1 | 1261 | 5.666 | 0.3808 | Yes | ||
40 | STAT2 | 1309 | 5.493 | 0.3845 | Yes | ||
41 | MAP4K4 | 1318 | 5.470 | 0.3903 | Yes | ||
42 | RPS6KA5 | 1326 | 5.445 | 0.3961 | Yes | ||
43 | MKNK2 | 1428 | 5.146 | 0.3965 | Yes | ||
44 | MARK2 | 1438 | 5.109 | 0.4018 | Yes | ||
45 | CASP1 | 1599 | 4.688 | 0.3984 | Yes | ||
46 | TRAF6 | 1695 | 4.456 | 0.3983 | Yes | ||
47 | STK17B | 1699 | 4.452 | 0.4032 | Yes | ||
48 | PKN1 | 1738 | 4.357 | 0.4061 | Yes | ||
49 | BIRC2 | 1743 | 4.343 | 0.4108 | Yes | ||
50 | PTEN | 1750 | 4.330 | 0.4155 | Yes | ||
51 | PIAS1 | 1786 | 4.255 | 0.4184 | Yes | ||
52 | PAK1 | 1819 | 4.193 | 0.4214 | Yes | ||
53 | STAMBP | 1902 | 4.018 | 0.4215 | Yes | ||
54 | TEC | 1903 | 4.018 | 0.4261 | Yes | ||
55 | EGF | 1914 | 3.994 | 0.4301 | Yes | ||
56 | STK4 | 1996 | 3.829 | 0.4300 | Yes | ||
57 | MAP3K4 | 2000 | 3.822 | 0.4342 | Yes | ||
58 | SPRED2 | 2022 | 3.783 | 0.4374 | Yes | ||
59 | SH2D3C | 2058 | 3.709 | 0.4397 | Yes | ||
60 | DUSP2 | 2086 | 3.662 | 0.4424 | Yes | ||
61 | TICAM2 | 2169 | 3.522 | 0.4419 | Yes | ||
62 | HIPK2 | 2183 | 3.501 | 0.4452 | Yes | ||
63 | MAP3K7IP1 | 2247 | 3.408 | 0.4457 | Yes | ||
64 | MAST1 | 2301 | 3.301 | 0.4465 | Yes | ||
65 | IKBKE | 2365 | 3.191 | 0.4467 | Yes | ||
66 | SNF1LK2 | 2405 | 3.135 | 0.4482 | Yes | ||
67 | ICK | 2426 | 3.105 | 0.4506 | Yes | ||
68 | CLCF1 | 2437 | 3.094 | 0.4536 | Yes | ||
69 | MAP3K12 | 2516 | 2.987 | 0.4528 | Yes | ||
70 | SOCS3 | 2592 | 2.869 | 0.4519 | Yes | ||
71 | SCOTIN | 2695 | 2.742 | 0.4495 | Yes | ||
72 | GHRL | 2713 | 2.717 | 0.4517 | Yes | ||
73 | DUSP4 | 2783 | 2.646 | 0.4509 | Yes | ||
74 | FPR1 | 2808 | 2.618 | 0.4526 | Yes | ||
75 | CXCR4 | 2830 | 2.592 | 0.4544 | Yes | ||
76 | CRKL | 2883 | 2.519 | 0.4545 | Yes | ||
77 | GPS2 | 2898 | 2.502 | 0.4565 | Yes | ||
78 | BST2 | 2923 | 2.478 | 0.4581 | Yes | ||
79 | CCM2 | 2951 | 2.444 | 0.4594 | Yes | ||
80 | OTUD7B | 2991 | 2.407 | 0.4600 | Yes | ||
81 | RELA | 3122 | 2.279 | 0.4555 | No | ||
82 | NF1 | 3132 | 2.270 | 0.4576 | No | ||
83 | SLC20A1 | 3185 | 2.213 | 0.4573 | No | ||
84 | FGFR1 | 3267 | 2.130 | 0.4553 | No | ||
85 | TNFSF14 | 3289 | 2.113 | 0.4566 | No | ||
86 | MAPK8IP3 | 3326 | 2.079 | 0.4570 | No | ||
87 | NOD2 | 3328 | 2.078 | 0.4593 | No | ||
88 | SOD1 | 3392 | 2.020 | 0.4581 | No | ||
89 | TRAF2 | 3441 | 1.978 | 0.4578 | No | ||
90 | MADD | 3479 | 1.951 | 0.4580 | No | ||
91 | IFNAR1 | 3707 | 1.777 | 0.4476 | No | ||
92 | ECT2 | 3725 | 1.767 | 0.4487 | No | ||
93 | MAPK13 | 3729 | 1.763 | 0.4506 | No | ||
94 | MAP4K5 | 3731 | 1.762 | 0.4525 | No | ||
95 | RPL17 | 3757 | 1.741 | 0.4531 | No | ||
96 | ATP2C1 | 3794 | 1.714 | 0.4531 | No | ||
97 | TLR6 | 3837 | 1.686 | 0.4528 | No | ||
98 | NDFIP2 | 3919 | 1.627 | 0.4502 | No | ||
99 | ITGB1BP1 | 4027 | 1.565 | 0.4462 | No | ||
100 | CCL2 | 4155 | 1.500 | 0.4410 | No | ||
101 | IL20 | 4327 | 1.396 | 0.4332 | No | ||
102 | CAMKK2 | 4430 | 1.334 | 0.4292 | No | ||
103 | FGF13 | 4501 | 1.284 | 0.4269 | No | ||
104 | NDFIP1 | 4541 | 1.255 | 0.4262 | No | ||
105 | F2 | 4543 | 1.254 | 0.4275 | No | ||
106 | MAP3K6 | 4546 | 1.253 | 0.4288 | No | ||
107 | FYB | 4551 | 1.249 | 0.4301 | No | ||
108 | EDARADD | 4631 | 1.207 | 0.4271 | No | ||
109 | MAP3K7 | 4650 | 1.199 | 0.4275 | No | ||
110 | DUSP9 | 4687 | 1.184 | 0.4269 | No | ||
111 | NMI | 4723 | 1.170 | 0.4263 | No | ||
112 | PROK2 | 4782 | 1.139 | 0.4245 | No | ||
113 | GJA1 | 5076 | 1.003 | 0.4097 | No | ||
114 | FKBP1A | 5087 | 1.000 | 0.4102 | No | ||
115 | LTBR | 5191 | 0.951 | 0.4057 | No | ||
116 | DUSP16 | 5206 | 0.944 | 0.4060 | No | ||
117 | MBIP | 5436 | 0.842 | 0.3945 | No | ||
118 | RHOC | 5496 | 0.819 | 0.3922 | No | ||
119 | ECM1 | 5591 | 0.778 | 0.3880 | No | ||
120 | ERC1 | 5597 | 0.776 | 0.3886 | No | ||
121 | EDG2 | 5754 | 0.712 | 0.3809 | No | ||
122 | TDGF1 | 5880 | 0.672 | 0.3749 | No | ||
123 | ADRA1A | 6054 | 0.600 | 0.3662 | No | ||
124 | SOCS6 | 6174 | 0.553 | 0.3603 | No | ||
125 | HGS | 6212 | 0.538 | 0.3589 | No | ||
126 | ADRB3 | 6216 | 0.536 | 0.3594 | No | ||
127 | STK3 | 6237 | 0.529 | 0.3589 | No | ||
128 | STK38 | 6343 | 0.490 | 0.3537 | No | ||
129 | C5AR1 | 6349 | 0.487 | 0.3540 | No | ||
130 | EPGN | 6360 | 0.484 | 0.3540 | No | ||
131 | TRIP6 | 6397 | 0.472 | 0.3526 | No | ||
132 | NF2 | 6410 | 0.468 | 0.3525 | No | ||
133 | LYN | 6633 | 0.389 | 0.3408 | No | ||
134 | MINK1 | 6663 | 0.378 | 0.3397 | No | ||
135 | ADORA2B | 6691 | 0.370 | 0.3386 | No | ||
136 | MAP3K9 | 6971 | 0.277 | 0.3238 | No | ||
137 | TNFSF15 | 6989 | 0.270 | 0.3231 | No | ||
138 | DAPK1 | 7043 | 0.251 | 0.3205 | No | ||
139 | NLK | 7210 | 0.198 | 0.3117 | No | ||
140 | MAP3K2 | 7250 | 0.182 | 0.3098 | No | ||
141 | BCL10 | 7310 | 0.166 | 0.3068 | No | ||
142 | DAXX | 7334 | 0.157 | 0.3057 | No | ||
143 | EDA2R | 7380 | 0.148 | 0.3034 | No | ||
144 | GNG3 | 7415 | 0.137 | 0.3017 | No | ||
145 | PRDX4 | 7535 | 0.102 | 0.2954 | No | ||
146 | FASLG | 7706 | 0.045 | 0.2862 | No | ||
147 | TRIM13 | 7947 | -0.022 | 0.2731 | No | ||
148 | IRAK1BP1 | 8253 | -0.120 | 0.2567 | No | ||
149 | CANT1 | 8383 | -0.158 | 0.2498 | No | ||
150 | STAT5B | 8605 | -0.224 | 0.2380 | No | ||
151 | WNK4 | 8762 | -0.275 | 0.2299 | No | ||
152 | MDFI | 8881 | -0.309 | 0.2238 | No | ||
153 | IL31RA | 9040 | -0.353 | 0.2156 | No | ||
154 | CCR2 | 9217 | -0.402 | 0.2065 | No | ||
155 | DUSP10 | 9386 | -0.454 | 0.1978 | No | ||
156 | PLCE1 | 9542 | -0.499 | 0.1900 | No | ||
157 | WNK3 | 9732 | -0.553 | 0.1803 | No | ||
158 | TPD52L1 | 9799 | -0.572 | 0.1774 | No | ||
159 | CHRNA7 | 10024 | -0.636 | 0.1659 | No | ||
160 | FGFR3 | 10044 | -0.643 | 0.1656 | No | ||
161 | TGFA | 10058 | -0.645 | 0.1656 | No | ||
162 | SCG2 | 10107 | -0.660 | 0.1638 | No | ||
163 | SRPK2 | 10282 | -0.703 | 0.1551 | No | ||
164 | PPM1A | 10469 | -0.756 | 0.1458 | No | ||
165 | FGF2 | 10689 | -0.821 | 0.1348 | No | ||
166 | MAP3K10 | 10737 | -0.835 | 0.1332 | No | ||
167 | RHOA | 10740 | -0.836 | 0.1341 | No | ||
168 | TAOK2 | 10760 | -0.840 | 0.1340 | No | ||
169 | NEK6 | 10801 | -0.849 | 0.1328 | No | ||
170 | MAP2K7 | 11372 | -1.011 | 0.1029 | No | ||
171 | SGK2 | 11418 | -1.025 | 0.1016 | No | ||
172 | REL | 11573 | -1.065 | 0.0945 | No | ||
173 | CFLAR | 11581 | -1.067 | 0.0953 | No | ||
174 | IRAK2 | 11674 | -1.098 | 0.0915 | No | ||
175 | AKAP11 | 11701 | -1.105 | 0.0914 | No | ||
176 | LATS2 | 11733 | -1.118 | 0.0910 | No | ||
177 | MAPK8IP2 | 11852 | -1.156 | 0.0858 | No | ||
178 | PLK2 | 11853 | -1.157 | 0.0872 | No | ||
179 | ADRA1B | 11968 | -1.190 | 0.0823 | No | ||
180 | SRC | 12150 | -1.245 | 0.0739 | No | ||
181 | CARTPT | 12235 | -1.268 | 0.0707 | No | ||
182 | HTR2B | 12268 | -1.278 | 0.0705 | No | ||
183 | GSG2 | 12291 | -1.284 | 0.0707 | No | ||
184 | MAP2K4 | 12313 | -1.290 | 0.0710 | No | ||
185 | TRAF7 | 12588 | -1.371 | 0.0577 | No | ||
186 | ADRA2A | 12712 | -1.415 | 0.0526 | No | ||
187 | GADD45G | 12780 | -1.438 | 0.0506 | No | ||
188 | NRTN | 12863 | -1.464 | 0.0478 | No | ||
189 | SHC1 | 12913 | -1.483 | 0.0468 | No | ||
190 | ADRB2 | 13000 | -1.509 | 0.0439 | No | ||
191 | MKNK1 | 13042 | -1.520 | 0.0433 | No | ||
192 | MAPK11 | 13069 | -1.528 | 0.0437 | No | ||
193 | MAP3K13 | 13202 | -1.576 | 0.0383 | No | ||
194 | F2R | 13208 | -1.578 | 0.0398 | No | ||
195 | SNF1LK | 13289 | -1.610 | 0.0373 | No | ||
196 | NEK11 | 13495 | -1.690 | 0.0280 | No | ||
197 | FLNA | 13554 | -1.716 | 0.0268 | No | ||
198 | NUP62 | 13644 | -1.743 | 0.0240 | No | ||
199 | PRKAG3 | 13764 | -1.796 | 0.0195 | No | ||
200 | PPP5C | 13785 | -1.807 | 0.0205 | No | ||
201 | MYD88 | 13838 | -1.828 | 0.0198 | No | ||
202 | HMOX1 | 14154 | -1.968 | 0.0049 | No | ||
203 | MAPK10 | 14173 | -1.978 | 0.0061 | No | ||
204 | GRM4 | 14237 | -2.007 | 0.0050 | No | ||
205 | DUSP8 | 14240 | -2.010 | 0.0072 | No | ||
206 | IL22RA2 | 14331 | -2.055 | 0.0046 | No | ||
207 | CXXC5 | 14409 | -2.096 | 0.0028 | No | ||
208 | RHOH | 14419 | -2.100 | 0.0047 | No | ||
209 | CARD10 | 14476 | -2.132 | 0.0041 | No | ||
210 | TNFRSF10B | 14515 | -2.155 | 0.0044 | No | ||
211 | IRAK1 | 14586 | -2.187 | 0.0031 | No | ||
212 | MARK1 | 14610 | -2.200 | 0.0044 | No | ||
213 | ATP6AP2 | 15082 | -2.477 | -0.0184 | No | ||
214 | VAPA | 15108 | -2.498 | -0.0170 | No | ||
215 | GADD45B | 15153 | -2.533 | -0.0165 | No | ||
216 | DAPK3 | 15265 | -2.613 | -0.0195 | No | ||
217 | ADAM9 | 15294 | -2.638 | -0.0181 | No | ||
218 | SPRED1 | 15312 | -2.650 | -0.0160 | No | ||
219 | RGS4 | 15388 | -2.709 | -0.0170 | No | ||
220 | STK38L | 15443 | -2.749 | -0.0168 | No | ||
221 | UBE2V1 | 15570 | -2.851 | -0.0204 | No | ||
222 | SECTM1 | 15642 | -2.910 | -0.0210 | No | ||
223 | MAPK8 | 15721 | -2.984 | -0.0218 | No | ||
224 | CD40 | 15735 | -3.002 | -0.0191 | No | ||
225 | BCL3 | 15747 | -3.008 | -0.0163 | No | ||
226 | FAF1 | 15891 | -3.176 | -0.0204 | No | ||
227 | UBE2N | 15900 | -3.182 | -0.0173 | No | ||
228 | MALT1 | 16052 | -3.358 | -0.0217 | No | ||
229 | RGS3 | 16253 | -3.614 | -0.0284 | No | ||
230 | DBNL | 16363 | -3.776 | -0.0301 | No | ||
231 | RIPK2 | 16429 | -3.880 | -0.0292 | No | ||
232 | SOCS1 | 16831 | -4.638 | -0.0457 | No | ||
233 | CHUK | 16867 | -4.706 | -0.0423 | No | ||
234 | ZDHHC13 | 16945 | -4.837 | -0.0410 | No | ||
235 | DAPK2 | 16947 | -4.841 | -0.0355 | No | ||
236 | CD24 | 17062 | -5.087 | -0.0359 | No | ||
237 | GPS1 | 17359 | -5.895 | -0.0453 | No | ||
238 | DUSP22 | 17467 | -6.214 | -0.0441 | No | ||
239 | FADD | 17662 | -6.940 | -0.0468 | No | ||
240 | PIK3CB | 17904 | -7.974 | -0.0508 | No | ||
241 | EEF1D | 17959 | -8.291 | -0.0443 | No | ||
242 | ADRA2C | 18062 | -8.915 | -0.0397 | No | ||
243 | GPR89A | 18077 | -9.023 | -0.0302 | No | ||
244 | SRPK1 | 18148 | -9.613 | -0.0231 | No | ||
245 | TRAF5 | 18219 | -10.189 | -0.0153 | No | ||
246 | MAP4K1 | 18224 | -10.205 | -0.0039 | No | ||
247 | BLK | 18601 | -22.135 | 0.0008 | No |