Datasetset04_transDMproB_versus_DMpreB
PhenotypeNoPhenotypeAvailable
Upregulated in classna_neg
GeneSetREACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS
Enrichment Score (ES)-0.76448226
Normalized Enrichment Score (NES)-2.0728552
Nominal p-value0.0
FDR q-value5.191176E-5
FWER p-Value0.0010
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CDC25C28622.542-0.1359No
2ORC4L10682-0.819-0.5507No
3RPA111919-1.172-0.6088No
4CDC712992-1.507-0.6558No
5MCM513849-1.833-0.6888No
6RAD115257-2.607-0.7460Yes
7MCM215360-2.690-0.7323Yes
8MCM615736-3.002-0.7312Yes
9MCM416312-3.695-0.7359Yes
10CDK216319-3.710-0.7099Yes
11MCM716403-3.842-0.6870Yes
12CDC25A16478-3.968-0.6628Yes
13RPA316771-4.515-0.6465Yes
14MCM316797-4.561-0.6154Yes
15MCM1016938-4.828-0.5886Yes
16HUS117006-4.961-0.5570Yes
17CHEK117258-5.616-0.5306Yes
18RAD9B17717-7.153-0.5045Yes
19CDC45L17767-7.357-0.4548Yes
20RFC517863-7.807-0.4045Yes
21ORC1L17922-8.076-0.3503Yes
22RPA217977-8.392-0.2936Yes
23RFC318061-8.903-0.2348Yes
24RFC418097-9.168-0.1716Yes
25ORC2L18387-12.097-0.1012Yes
26ORC5L18543-15.9720.0039Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS: Random ES distribution   
Gene set null distribution of ES for REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS