Details for gene set DNA_METABOLIC

Table: GSEA Results Summary

Dataset	set04_transDMpreB_versus_WTpreB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	DNA_METABOLIC_PROCESS
Enrichment Score (ES)	0.5521765
Normalized Enrichment Score (NES)	2.1083567
Nominal p-value	0.0
FDR q-value	5.6090492E-5
FWER p-Value	0.0010

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CDKN2A	0	53.800	0.0583	Yes
2	NTHL1	150	12.612	0.0638	Yes
3	POLD2	156	12.471	0.0771	Yes
4	POLE	169	12.131	0.0895	Yes
5	APEX1	203	11.418	0.1001	Yes
6	RAD54L	232	10.938	0.1104	Yes
7	POLE3	248	10.705	0.1212	Yes
8	ATR	291	10.249	0.1300	Yes
9	GTF2H4	314	9.906	0.1396	Yes
10	MPG	363	9.439	0.1472	Yes
11	UNG	369	9.391	0.1571	Yes
12	XRN2	395	9.212	0.1657	Yes
13	SUPV3L1	422	8.971	0.1740	Yes
14	RUVBL2	469	8.535	0.1807	Yes
15	MLH1	474	8.505	0.1897	Yes
16	BLM	489	8.427	0.1981	Yes
17	ERCC8	506	8.311	0.2062	Yes
18	CDC6	519	8.180	0.2144	Yes
19	RAD51L1	530	8.090	0.2226	Yes
20	ORC1L	539	7.998	0.2309	Yes
21	RECQL4	560	7.876	0.2383	Yes
22	ATM	592	7.645	0.2449	Yes
23	LIG1	596	7.629	0.2530	Yes
24	RPA1	599	7.604	0.2611	Yes
25	BAX	601	7.598	0.2693	Yes
26	LIG3	612	7.530	0.2769	Yes
27	NASP	618	7.483	0.2847	Yes
28	GTF2H1	671	7.198	0.2897	Yes
29	GTPBP4	692	7.069	0.2963	Yes
30	MCM7	698	7.027	0.3036	Yes
31	MCM3	731	6.865	0.3093	Yes
32	NBN	733	6.858	0.3167	Yes
33	KCTD13	737	6.838	0.3239	Yes
34	PARP1	742	6.797	0.3311	Yes
35	RAD51	776	6.691	0.3365	Yes
36	ERCC1	799	6.622	0.3425	Yes
37	DNMT1	808	6.587	0.3492	Yes
38	RFC1	811	6.571	0.3562	Yes
39	RPA2	849	6.392	0.3611	Yes
40	MUTYH	858	6.356	0.3676	Yes
41	RFC4	865	6.344	0.3741	Yes
42	NT5E	917	6.120	0.3780	Yes
43	AIFM1	930	6.055	0.3839	Yes
44	POLI	937	6.030	0.3901	Yes
45	MCM5	946	5.989	0.3961	Yes
46	REV1	958	5.959	0.4020	Yes
47	MCM2	987	5.859	0.4068	Yes
48	MRE11A	1007	5.796	0.4120	Yes
49	PTGES3	1040	5.650	0.4164	Yes
50	TIPIN	1046	5.625	0.4222	Yes
51	CYCS	1054	5.594	0.4279	Yes
52	POLL	1065	5.547	0.4334	Yes
53	NAP1L1	1102	5.432	0.4373	Yes
54	FEN1	1108	5.410	0.4429	Yes
55	SMARCAD1	1149	5.287	0.4465	Yes
56	PMS2	1165	5.226	0.4513	Yes
57	GMNN	1187	5.154	0.4557	Yes
58	RECQL	1191	5.141	0.4611	Yes
59	BRCA2	1219	5.051	0.4651	Yes
60	MSH2	1227	5.033	0.4702	Yes
61	DNMT3B	1228	5.032	0.4757	Yes
62	POLG	1293	4.860	0.4774	Yes
63	HUS1	1296	4.845	0.4826	Yes
64	POLG2	1323	4.772	0.4863	Yes
65	CDK2	1330	4.747	0.4912	Yes
66	XRCC2	1342	4.712	0.4957	Yes
67	UPF1	1428	4.452	0.4959	Yes
68	CDC45L	1439	4.404	0.5001	Yes
69	RAD50	1454	4.376	0.5041	Yes
70	RNASEH2A	1507	4.265	0.5059	Yes
71	CDT1	1518	4.239	0.5099	Yes
72	XRCC3	1562	4.140	0.5120	Yes
73	EXO1	1593	4.077	0.5148	Yes
74	ORC5L	1613	4.030	0.5182	Yes
75	CDK2AP1	1666	3.924	0.5196	Yes
76	SMC1A	1682	3.894	0.5230	Yes
77	PRIM1	1730	3.806	0.5246	Yes
78	POLQ	1796	3.669	0.5250	Yes
79	CHEK1	1871	3.510	0.5248	Yes
80	UBE2N	1902	3.451	0.5269	Yes
81	DDB1	1909	3.446	0.5303	Yes
82	RPA3	1932	3.406	0.5328	Yes
83	HMGB1	2001	3.300	0.5327	Yes
84	TFAM	2008	3.288	0.5359	Yes
85	PICK1	2097	3.151	0.5345	Yes
86	RAN	2109	3.130	0.5373	Yes
87	RAD1	2116	3.125	0.5404	Yes
88	RECQL5	2133	3.097	0.5428	Yes
89	MSH6	2162	3.058	0.5446	Yes
90	MSH3	2257	2.909	0.5427	Yes
91	ORC2L	2314	2.841	0.5427	Yes
92	RAD23A	2315	2.840	0.5458	Yes
93	TOP2A	2322	2.831	0.5485	Yes
94	DFFA	2340	2.805	0.5506	Yes
95	KPNA2	2441	2.674	0.5481	Yes
96	BRCA1	2502	2.617	0.5477	Yes
97	MNAT1	2523	2.593	0.5494	Yes
98	CSNK1D	2549	2.571	0.5508	Yes
99	FANCA	2625	2.498	0.5494	Yes
100	S100A11	2655	2.475	0.5505	Yes
101	DDB2	2675	2.458	0.5522	Yes
102	RFC3	2794	2.354	0.5483	No
103	TSN	2864	2.290	0.5470	No
104	SOD1	2924	2.241	0.5463	No
105	SUMO1	2970	2.200	0.5462	No
106	BNIP3	3011	2.164	0.5464	No
107	IL4	3049	2.137	0.5467	No
108	UBE2V2	3140	2.074	0.5440	No
109	FOXL2	3221	2.015	0.5419	No
110	PMS1	3284	1.964	0.5406	No
111	FANCC	3405	1.873	0.5361	No
112	XRCC5	3611	1.754	0.5269	No
113	REV3L	3642	1.740	0.5271	No
114	TNP1	3696	1.710	0.5261	No
115	DMAP1	3804	1.651	0.5221	No
116	NF2	3819	1.643	0.5231	No
117	ATRX	4191	1.476	0.5045	No
118	TERF2	4244	1.454	0.5033	No
119	EGF	4448	1.375	0.4937	No
120	TDG	4455	1.373	0.4949	No
121	DNMT3A	5090	1.145	0.4616	No
122	GLI2	5585	0.989	0.4359	No
123	SET	5617	0.980	0.4352	No
124	POLK	5788	0.928	0.4270	No
125	TNFSF13	6362	0.773	0.3967	No
126	EREG	6381	0.769	0.3965	No
127	RBMS1	6386	0.768	0.3972	No
128	ERCC3	6652	0.699	0.3835	No
129	MYST2	6664	0.695	0.3837	No
130	MCM3AP	6722	0.681	0.3813	No
131	OGG1	6817	0.655	0.3769	No
132	POLE2	6876	0.639	0.3744	No
133	RAD21	6976	0.612	0.3697	No
134	IGFBP4	7295	0.538	0.3530	No
135	IGF1	7424	0.506	0.3466	No
136	ADRA1D	7456	0.496	0.3454	No
137	HMGB2	7503	0.482	0.3435	No
138	TERT	7582	0.465	0.3397	No
139	XPC	7606	0.457	0.3390	No
140	FANCG	7678	0.437	0.3356	No
141	CD40LG	7935	0.373	0.3221	No
142	POT1	8078	0.338	0.3147	No
143	MSH4	8087	0.336	0.3147	No
144	RAD23B	8139	0.322	0.3122	No
145	SMARCB1	8603	0.208	0.2873	No
146	UBE2B	8785	0.165	0.2776	No
147	KIN	8791	0.163	0.2775	No
148	TLK1	8806	0.160	0.2769	No
149	NUP98	8813	0.159	0.2768	No
150	FOS	9018	0.107	0.2658	No
151	VCP	9019	0.106	0.2659	No
152	DMC1	9027	0.105	0.2657	No
153	GLI1	9322	0.027	0.2497	No
154	UBE2V1	9490	-0.019	0.2406	No
155	ACHE	9716	-0.075	0.2285	No
156	POLA1	9723	-0.077	0.2283	No
157	TEP1	9743	-0.082	0.2273	No
158	NP	9843	-0.112	0.2220	No
159	POLH	9902	-0.129	0.2190	No
160	CIDEA	9909	-0.131	0.2189	No
161	SPO11	10160	-0.189	0.2055	No
162	TREX2	10290	-0.218	0.1987	No
163	ALKBH1	10491	-0.258	0.1881	No
164	PURA	10543	-0.271	0.1856	No
165	HTATIP	10913	-0.364	0.1659	No
166	ATXN3	11069	-0.401	0.1580	No
167	TERF2IP	11186	-0.431	0.1521	No
168	IGHMBP2	12539	-0.811	0.0795	No
169	XRCC6	12541	-0.812	0.0803	No
170	RAD17	12739	-0.871	0.0706	No
171	TBRG1	12867	-0.908	0.0646	No
172	KPNA1	12962	-0.933	0.0605	No
173	SMARCAL1	13050	-0.956	0.0568	No
174	ORC3L	13414	-1.092	0.0383	No
175	RAD51C	13755	-1.233	0.0211	No
176	DFFB	13855	-1.270	0.0171	No
177	MGMT	13919	-1.291	0.0151	No
178	XAB2	14038	-1.337	0.0101	No
179	HELLS	14153	-1.381	0.0054	No
180	RAD51L3	14401	-1.478	-0.0064	No
181	SYCP1	14422	-1.491	-0.0059	No
182	BTG2	14485	-1.514	-0.0076	No
183	TPD52L1	14533	-1.539	-0.0085	No
184	ISG20	14584	-1.557	-0.0095	No
185	SMG6	14694	-1.624	-0.0137	No
186	ORC4L	15008	-1.805	-0.0287	No
187	ABL1	15100	-1.861	-0.0317	No
188	CIB1	15143	-1.893	-0.0319	No
189	RAD52	15206	-1.941	-0.0332	No
190	PPARGC1A	15223	-1.951	-0.0319	No
191	WRNIP1	15437	-2.118	-0.0412	No
192	TINF2	15602	-2.253	-0.0477	No
193	XRCC4	15793	-2.429	-0.0554	No
194	TLK2	16170	-2.871	-0.0727	No
195	SETMAR	16412	-3.229	-0.0823	No
196	APTX	16505	-3.388	-0.0837	No
197	PPT1	16678	-3.700	-0.0890	No
198	RAD9A	16717	-3.761	-0.0870	No
199	POLD1	16812	-3.942	-0.0878	No
200	CECR2	16814	-3.948	-0.0836	No
201	NT5M	16885	-4.101	-0.0830	No
202	ERCC4	16893	-4.124	-0.0789	No
203	CSNK1E	16961	-4.282	-0.0779	No
204	REPIN1	17000	-4.388	-0.0752	No
205	ERCC5	17123	-4.746	-0.0767	No
206	PNKP	17140	-4.779	-0.0724	No
207	GADD45G	17181	-4.886	-0.0693	No
208	POLB	17210	-4.968	-0.0654	No
209	SMUG1	17441	-5.666	-0.0718	No
210	UBE2A	17557	-6.086	-0.0715	No
211	TGFB1	17710	-6.583	-0.0726	No
212	ASF1A	17797	-6.919	-0.0698	No
213	RAG1	17876	-7.322	-0.0661	No
214	ATF7IP	17898	-7.456	-0.0592	No
215	ERCC2	17992	-7.856	-0.0557	No
216	IL7R	18135	-8.992	-0.0537	No
217	LIG4	18180	-9.284	-0.0460	No
218	POLD4	18204	-9.516	-0.0370	No
219	TP53	18216	-9.624	-0.0272	No
220	DNASE2	18260	-10.054	-0.0186	No
221	MSH5	18267	-10.104	-0.0080	No
222	GADD45A	18296	-10.483	0.0018	No
223	CDKN2D	18478	-14.310	0.0075	No