Details for gene set HSA04620_TOLL_LIKE_RECEPTOR_SIGNALING

Table: GSEA Results Summary

Dataset	set04_transDMpreB_versus_WTpreB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	HSA04620_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.5579313
Normalized Enrichment Score (NES)	-1.6870089
Nominal p-value	0.020933978
FDR q-value	0.536762
FWER p-Value	0.998

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PIK3CB	882	6.246	-0.0295	No
2	TIRAP	928	6.071	-0.0144	No
3	MAP3K7	972	5.905	0.0004	No
4	MAPK11	1109	5.409	0.0087	No
5	CD86	1255	4.945	0.0151	No
6	MAPK12	1269	4.916	0.0287	No
7	PIK3R3	1472	4.347	0.0303	No
8	IRAK1	1556	4.142	0.0378	No
9	TICAM2	1771	3.735	0.0371	No
10	IKBKB	1959	3.365	0.0367	No
11	MAPK8	2179	3.027	0.0337	No
12	CHUK	2221	2.966	0.0400	No
13	TRAF3	2235	2.939	0.0478	No
14	MAP3K7IP1	2375	2.758	0.0483	No
15	NFKB2	2856	2.303	0.0291	No
16	AKT1	2974	2.198	0.0291	No
17	MYD88	3117	2.089	0.0275	No
18	IFNA7	3369	1.898	0.0194	No
19	MAP2K1	3408	1.872	0.0228	No
20	TLR7	3761	1.674	0.0086	No
21	CXCL9	4028	1.545	-0.0013	No
22	IFNA14	4331	1.417	-0.0135	No
23	IFNA1	5032	1.160	-0.0479	No
24	IL6	5329	1.073	-0.0608	No
25	MAP2K2	5396	1.043	-0.0613	No
26	CD14	5445	1.030	-0.0609	No
27	IFNA4	5556	0.996	-0.0640	No
28	IL1B	5762	0.937	-0.0724	No
29	TLR8	5844	0.911	-0.0741	No
30	PIK3R5	6715	0.682	-0.1191	No
31	IFNB1	6917	0.628	-0.1281	No
32	CCL4	7202	0.559	-0.1418	No
33	CCL5	7441	0.500	-0.1532	No
34	TBK1	7451	0.497	-0.1523	No
35	MAPK13	7624	0.451	-0.1603	No
36	PIK3R2	7997	0.358	-0.1793	No
37	TLR5	8401	0.256	-0.2003	No
38	CCL3	8496	0.235	-0.2047	No
39	LBP	8551	0.219	-0.2070	No
40	CXCL11	8643	0.198	-0.2113	No
41	IL12B	8737	0.175	-0.2159	No
42	FOS	9018	0.107	-0.2307	No
43	MAP3K8	9126	0.078	-0.2362	No
44	TLR3	10326	-0.226	-0.3003	No
45	IFNAR1	10371	-0.234	-0.3020	No
46	IFNA6	10510	-0.262	-0.3087	No
47	MAP2K7	10828	-0.340	-0.3248	No
48	IKBKE	10915	-0.364	-0.3284	No
49	TLR9	11539	-0.517	-0.3606	No
50	IFNA2	11632	-0.543	-0.3639	No
51	PIK3R1	11865	-0.608	-0.3747	No
52	LY96	12097	-0.675	-0.3852	No
53	TNF	12300	-0.734	-0.3940	No
54	IRF7	12392	-0.765	-0.3967	No
55	RIPK1	12399	-0.767	-0.3948	No
56	IFNA13	12517	-0.806	-0.3988	No
57	CD80	12540	-0.812	-0.3976	No
58	FADD	12551	-0.815	-0.3958	No
59	IRF5	12706	-0.862	-0.4016	No
60	CXCL10	13979	-1.314	-0.4665	No
61	MAP2K3	14531	-1.538	-0.4918	No
62	MAPK14	14537	-1.541	-0.4876	No
63	TLR4	14840	-1.707	-0.4990	No
64	RAC1	14926	-1.756	-0.4985	No
65	MAPK10	15352	-2.059	-0.5155	No
66	CASP8	15978	-2.634	-0.5416	No
67	MAP2K6	16017	-2.684	-0.5359	No
68	PIK3CA	16426	-3.246	-0.5485	Yes
69	IFNA5	16446	-3.285	-0.5401	Yes
70	IKBKG	16553	-3.477	-0.5357	Yes
71	PIK3CD	16600	-3.558	-0.5279	Yes
72	MAP2K4	17006	-4.402	-0.5370	Yes
73	IL12A	17038	-4.515	-0.5257	Yes
74	RELA	17065	-4.586	-0.5138	Yes
75	JUN	17135	-4.762	-0.5037	Yes
76	IRAK4	17160	-4.845	-0.4910	Yes
77	IRF3	17225	-5.005	-0.4800	Yes
78	MAP3K7IP2	17275	-5.161	-0.4677	Yes
79	MAPK3	17335	-5.344	-0.4554	Yes
80	NFKB1	17383	-5.487	-0.4421	Yes
81	MAPK9	17593	-6.221	-0.4354	Yes
82	NFKBIA	17625	-6.306	-0.4188	Yes
83	TOLLIP	17725	-6.647	-0.4049	Yes
84	MAPK1	17787	-6.868	-0.3883	Yes
85	CD40	17901	-7.482	-0.3728	Yes
86	AKT2	18046	-8.193	-0.3568	Yes
87	AKT3	18107	-8.687	-0.3350	Yes
88	PIK3CG	18147	-9.020	-0.3110	Yes
89	IFNAR2	18192	-9.427	-0.2861	Yes
90	TRAF6	18232	-9.851	-0.2597	Yes
91	STAT1	18246	-9.978	-0.2315	Yes
92	TLR2	18257	-10.040	-0.2030	Yes
93	TLR1	18465	-13.850	-0.1741	Yes
94	SPP1	18561	-24.511	-0.1083	Yes
95	TLR6	18585	-38.435	0.0017	Yes