Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	set04_transDMpreB_versus_WTpreB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	0.5843934
Normalized Enrichment Score (NES)	2.0713422
Nominal p-value	0.0
FDR q-value	3.7017427E-4
FWER p-Value	0.0030

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	POLR1B	13	25.660	0.0431	Yes
2	IMPDH2	40	17.301	0.0712	Yes
3	NME2	80	14.966	0.0946	Yes
4	NME1	84	14.861	0.1198	Yes
5	ADK	94	14.400	0.1439	Yes
6	PPAT	107	13.796	0.1668	Yes
7	POLR1A	117	13.455	0.1893	Yes
8	POLD2	156	12.471	0.2085	Yes
9	GART	162	12.281	0.2292	Yes
10	AK2	163	12.258	0.2501	Yes
11	POLE	169	12.131	0.2706	Yes
12	APRT	214	11.235	0.2874	Yes
13	ADSL	220	11.140	0.3061	Yes
14	POLE3	248	10.705	0.3229	Yes
15	ADA	282	10.360	0.3388	Yes
16	PKM2	328	9.829	0.3532	Yes
17	POLR3H	329	9.824	0.3699	Yes
18	AMPD2	382	9.297	0.3830	Yes
19	ATIC	400	9.179	0.3977	Yes
20	NME6	403	9.141	0.4132	Yes
21	NME4	458	8.678	0.4251	Yes
22	NUDT5	485	8.446	0.4381	Yes
23	GMPS	496	8.376	0.4519	Yes
24	NUDT9	499	8.341	0.4660	Yes
25	RFC5	526	8.111	0.4784	Yes
26	POLA2	532	8.055	0.4919	Yes
27	POLD3	550	7.954	0.5046	Yes
28	POLR2J	575	7.790	0.5166	Yes
29	GUK1	586	7.684	0.5291	Yes
30	PAICS	703	6.999	0.5348	Yes
31	ENTPD4	723	6.900	0.5455	Yes
32	POLR2H	779	6.679	0.5540	Yes
33	NT5E	917	6.120	0.5570	Yes
34	NME7	1116	5.394	0.5555	Yes
35	RRM1	1140	5.328	0.5633	Yes
36	POLR2E	1154	5.265	0.5716	Yes
37	NUDT2	1265	4.922	0.5741	Yes
38	HPRT1	1487	4.299	0.5695	Yes
39	PDE8A	1584	4.096	0.5713	Yes
40	POLR3A	1611	4.041	0.5767	Yes
41	PRIM1	1730	3.806	0.5769	Yes
42	POLR2A	1817	3.619	0.5784	Yes
43	PRPS1	1821	3.615	0.5844	Yes
44	POLR1D	2137	3.094	0.5726	No
45	ALLC	2367	2.769	0.5650	No
46	ENTPD6	2415	2.702	0.5670	No
47	ECGF1	2450	2.669	0.5698	No
48	PNPT1	2584	2.537	0.5669	No
49	PRPS2	2741	2.402	0.5626	No
50	ADCY4	3289	1.959	0.5363	No
51	POLR2K	3525	1.806	0.5267	No
52	AK5	3715	1.699	0.5194	No
53	PDE10A	3795	1.656	0.5179	No
54	POLR2I	4456	1.372	0.4846	No
55	AK3L1	4952	1.179	0.4598	No
56	ADCY3	4978	1.172	0.4604	No
57	GDA	5162	1.120	0.4525	No
58	PAPSS2	5321	1.076	0.4457	No
59	ITPA	5342	1.069	0.4465	No
60	ENTPD8	5421	1.037	0.4440	No
61	GUCY2F	5796	0.927	0.4254	No
62	RRM2B	5910	0.894	0.4208	No
63	ENTPD3	6511	0.737	0.3896	No
64	POLE2	6876	0.639	0.3710	No
65	ENTPD1	7391	0.516	0.3441	No
66	PDE6G	7393	0.516	0.3449	No
67	GUCY1A2	7573	0.468	0.3360	No
68	XDH	7579	0.466	0.3366	No
69	AMPD1	7645	0.446	0.3338	No
70	POLR2C	8238	0.292	0.3023	No
71	ADCY8	8284	0.281	0.3003	No
72	PDE5A	8918	0.133	0.2663	No
73	NPR1	8969	0.120	0.2638	No
74	PDE2A	8981	0.117	0.2634	No
75	POLR3B	9239	0.048	0.2496	No
76	POLA1	9723	-0.077	0.2236	No
77	NP	9843	-0.112	0.2174	No
78	CANT1	10095	-0.177	0.2041	No
79	NPR2	10879	-0.353	0.1623	No
80	PDE1A	10898	-0.358	0.1620	No
81	GUCY2C	10979	-0.381	0.1583	No
82	PKLR	10999	-0.383	0.1579	No
83	PDE3B	11336	-0.469	0.1406	No
84	GUCY1B3	11433	-0.492	0.1362	No
85	PDE6H	11832	-0.601	0.1157	No
86	ENTPD2	12153	-0.690	0.0996	No
87	PDE1C	12339	-0.747	0.0908	No
88	PDE8B	12542	-0.812	0.0813	No
89	AK1	12586	-0.827	0.0804	No
90	ENPP3	12590	-0.827	0.0816	No
91	POLR2G	12990	-0.941	0.0617	No
92	ADCY6	13085	-0.972	0.0582	No
93	ENPP1	13138	-0.993	0.0571	No
94	PDE7B	13607	-1.175	0.0338	No
95	ADCY5	13922	-1.293	0.0190	No
96	GUCY1A3	14050	-1.339	0.0144	No
97	PDE9A	14063	-1.345	0.0161	No
98	NT5C3	14103	-1.363	0.0163	No
99	NT5C1B	14120	-1.369	0.0178	No
100	POLR2B	14675	-1.616	-0.0094	No
101	PDE4D	14829	-1.703	-0.0148	No
102	NT5C	15011	-1.805	-0.0215	No
103	IMPDH1	15354	-2.060	-0.0365	No
104	PDE4B	15360	-2.065	-0.0332	No
105	ADCY2	15475	-2.150	-0.0357	No
106	POLR3K	15639	-2.284	-0.0407	No
107	PDE11A	15727	-2.364	-0.0413	No
108	PDE4A	15759	-2.395	-0.0389	No
109	AMPD3	15964	-2.611	-0.0455	No
110	GMPR	15976	-2.634	-0.0416	No
111	FHIT	16098	-2.775	-0.0434	No
112	PDE4C	16213	-2.922	-0.0446	No
113	POLE4	16376	-3.172	-0.0479	No
114	ADCY9	16377	-3.172	-0.0425	No
115	PAPSS1	16811	-3.942	-0.0592	No
116	POLD1	16812	-3.942	-0.0525	No
117	NT5M	16885	-4.101	-0.0494	No
118	GMPR2	16887	-4.103	-0.0424	No
119	ZNRD1	17008	-4.403	-0.0414	No
120	ADCY7	17389	-5.510	-0.0526	No
121	RRM2	17427	-5.575	-0.0450	No
122	ENTPD5	17504	-5.927	-0.0390	No
123	NT5C2	17807	-6.965	-0.0435	No
124	ADSSL1	17927	-7.609	-0.0369	No
125	DGUOK	17976	-7.781	-0.0263	No
126	DCK	17991	-7.855	-0.0136	No
127	PDE7A	18037	-8.127	-0.0022	No
128	POLD4	18204	-9.516	0.0051	No
129	PDE6D	18258	-10.042	0.0194	No