Details for gene set HSA05210_COLORECTAL

Table: GSEA Results Summary

Dataset	set04_DMproB_versus_LMproB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	HSA05210_COLORECTAL_CANCER
Enrichment Score (ES)	-0.42450887
Normalized Enrichment Score (NES)	-1.6546649
Nominal p-value	0.007005254
FDR q-value	0.22526672
FWER p-Value	0.968

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	TCF7L2	348	2.868	0.0080	No
2	RAF1	835	2.156	0.0019	No
3	RAC2	867	2.129	0.0201	No
4	AXIN2	1139	1.906	0.0233	No
5	APC	1149	1.899	0.0405	No
6	PIK3CB	1268	1.823	0.0512	No
7	GRB2	1573	1.641	0.0501	No
8	SMAD3	1635	1.611	0.0619	No
9	BIRC5	1706	1.575	0.0728	No
10	IGF1R	1948	1.469	0.0735	No
11	TGFBR1	2378	1.313	0.0626	No
12	RALGDS	2481	1.279	0.0691	No
13	SMAD2	3188	1.075	0.0410	No
14	BCL2	3260	1.054	0.0470	No
15	MYC	3332	1.038	0.0529	No
16	MAPK10	3350	1.032	0.0616	No
17	FZD5	3437	1.009	0.0664	No
18	PIK3R5	3860	0.902	0.0520	No
19	TCF7	3887	0.897	0.0590	No
20	SOS1	4827	0.690	0.0148	No
21	EGFR	4843	0.688	0.0204	No
22	PIK3CG	4959	0.667	0.0204	No
23	PDGFRB	5027	0.654	0.0229	No
24	DVL2	5185	0.623	0.0203	No
25	FZD8	5553	0.555	0.0056	No
26	BAD	5594	0.547	0.0086	No
27	FZD9	5810	0.507	0.0017	No
28	MSH3	6163	0.445	-0.0131	No
29	APC2	6435	0.395	-0.0240	No
30	GSK3B	6584	0.372	-0.0286	No
31	PIK3R1	6623	0.366	-0.0272	No
32	AKT1	7194	0.267	-0.0554	No
33	PIK3R2	7294	0.252	-0.0584	No
34	CCND1	7311	0.248	-0.0570	No
35	PIK3CA	7419	0.232	-0.0606	No
36	MET	7521	0.217	-0.0640	No
37	PDGFRA	7692	0.189	-0.0714	No
38	FZD1	8380	0.083	-0.1077	No
39	FZD4	9029	-0.021	-0.1425	No
40	TGFB2	9260	-0.055	-0.1543	No
41	RAC1	9785	-0.132	-0.1814	No
42	TGFB1	10324	-0.214	-0.2084	No
43	SOS2	10339	-0.215	-0.2072	No
44	PIK3R3	10441	-0.230	-0.2105	No
45	AXIN1	10731	-0.281	-0.2234	No
46	MAP2K1	10757	-0.285	-0.2221	No
47	MAPK3	11428	-0.397	-0.2545	No
48	FZD10	11444	-0.399	-0.2516	No
49	MLH1	11650	-0.432	-0.2587	No
50	FZD7	11771	-0.451	-0.2609	No
51	TGFBR2	13088	-0.682	-0.3255	No
52	FZD2	13647	-0.777	-0.3484	No
53	FZD3	13841	-0.811	-0.3512	No
54	RAC3	14030	-0.849	-0.3535	No
55	DVL3	14034	-0.849	-0.3457	No
56	MSH6	14063	-0.855	-0.3392	No
57	CYCS	14621	-0.973	-0.3602	No
58	DVL1	15154	-1.097	-0.3786	No
59	CASP9	15313	-1.138	-0.3765	No
60	TGFB3	15487	-1.185	-0.3748	No
61	KRAS	15643	-1.222	-0.3718	No
62	AKT3	16533	-1.515	-0.4056	No
63	FOS	16885	-1.668	-0.4089	Yes
64	SMAD4	16907	-1.677	-0.3944	Yes
65	ARAF	17122	-1.791	-0.3892	Yes
66	ACVR1C	17221	-1.849	-0.3773	Yes
67	MAPK8	17416	-1.961	-0.3694	Yes
68	MAPK9	17583	-2.095	-0.3588	Yes
69	MSH2	17672	-2.155	-0.3434	Yes
70	CASP3	17902	-2.386	-0.3335	Yes
71	FZD6	17916	-2.402	-0.3118	Yes
72	AKT2	18092	-2.672	-0.2963	Yes
73	LEF1	18162	-2.778	-0.2741	Yes
74	DCC	18176	-2.820	-0.2485	Yes
75	MAPK1	18210	-2.885	-0.2233	Yes
76	PIK3CD	18319	-3.174	-0.1995	Yes
77	JUN	18337	-3.236	-0.1702	Yes
78	ACVR1B	18550	-4.949	-0.1354	Yes
79	TP53	18597	-7.392	-0.0689	Yes
80	BAX	18598	-7.485	0.0010	Yes