Details for gene set HSA04530_TIGHT

Table: GSEA Results Summary

Dataset	set04_DMproB_versus_LMproB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	HSA04530_TIGHT_JUNCTION
Enrichment Score (ES)	-0.4147397
Normalized Enrichment Score (NES)	-1.6959724
Nominal p-value	0.0
FDR q-value	0.25525165
FWER p-Value	0.912

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MYL9	77	4.222	0.0236	No
2	MYL2	222	3.278	0.0374	No
3	PRKCD	368	2.828	0.0482	No
4	CLDN15	439	2.698	0.0622	No
5	TJP3	442	2.693	0.0798	No
6	CLDN1	551	2.518	0.0905	No
7	ASH1L	763	2.224	0.0937	No
8	RRAS	770	2.216	0.1080	No
9	PRKCB1	1323	1.788	0.0900	No
10	CLDN5	1373	1.751	0.0988	No
11	MYH11	1554	1.650	0.1000	No
12	CLDN7	1633	1.611	0.1064	No
13	MYL7	1818	1.527	0.1065	No
14	MYLPF	1936	1.474	0.1099	No
15	JAM2	2317	1.329	0.0981	No
16	PRKCE	2978	1.130	0.0699	No
17	CLDN8	3467	0.999	0.0501	No
18	MYH9	3594	0.965	0.0497	No
19	CLDN11	4004	0.874	0.0333	No
20	CRB3	4033	0.866	0.0375	No
21	PPP2R4	4317	0.795	0.0275	No
22	CSNK2A1	4538	0.749	0.0205	No
23	ACTN4	5162	0.627	-0.0090	No
24	CASK	5415	0.581	-0.0188	No
25	CLDN23	5434	0.577	-0.0160	No
26	PRKCZ	5502	0.564	-0.0159	No
27	JAM3	5652	0.539	-0.0204	No
28	EXOC3	5952	0.483	-0.0333	No
29	CGN	5969	0.479	-0.0311	No
30	CLDN19	6138	0.449	-0.0372	No
31	CLDN9	6302	0.417	-0.0432	No
32	MRAS	6372	0.406	-0.0443	No
33	ACTG1	6729	0.351	-0.0612	No
34	AKT1	7194	0.267	-0.0845	No
35	VAPA	7587	0.206	-0.1043	No
36	CLDN2	7908	0.155	-0.1206	No
37	MYH3	7922	0.153	-0.1203	No
38	PTEN	8691	0.035	-0.1615	No
39	YES1	9079	-0.029	-0.1822	No
40	GNAI1	9326	-0.066	-0.1951	No
41	RAB13	9410	-0.079	-0.1990	No
42	PPP2R1A	9721	-0.123	-0.2150	No
43	NRAS	9973	-0.163	-0.2274	No
44	CSNK2B	10120	-0.184	-0.2341	No
45	PARD6G	10472	-0.236	-0.2515	No
46	PRKCI	10527	-0.246	-0.2528	No
47	CTTN	10612	-0.260	-0.2556	No
48	PPP2CB	11014	-0.328	-0.2751	No
49	PARD6B	11225	-0.365	-0.2841	No
50	PRKCQ	11256	-0.370	-0.2832	No
51	CLDN18	11569	-0.419	-0.2973	No
52	MYH4	11785	-0.453	-0.3060	No
53	PPP2CA	11880	-0.467	-0.3080	No
54	MPDZ	11938	-0.476	-0.3079	No
55	MYH6	12475	-0.571	-0.3331	No
56	MYH2	12489	-0.575	-0.3300	No
57	MYH7	13325	-0.717	-0.3704	No
58	CLDN4	13565	-0.762	-0.3783	No
59	ACTN3	13692	-0.784	-0.3799	No
60	PARD6A	13897	-0.822	-0.3855	No
61	PARD3	14104	-0.863	-0.3910	No
62	RAB3B	14121	-0.866	-0.3861	No
63	MYH14	14626	-0.974	-0.4069	Yes
64	TJP1	14653	-0.979	-0.4019	Yes
65	RHOA	14709	-0.991	-0.3984	Yes
66	CLDN17	14932	-1.043	-0.4035	Yes
67	SRC	14989	-1.055	-0.3996	Yes
68	HRAS	15010	-1.058	-0.3937	Yes
69	CLDN10	15043	-1.068	-0.3884	Yes
70	PPP2R2A	15090	-1.079	-0.3838	Yes
71	PPM1J	15576	-1.208	-0.4020	Yes
72	CLDN14	15627	-1.218	-0.3967	Yes
73	GNAI3	15629	-1.219	-0.3887	Yes
74	KRAS	15643	-1.222	-0.3814	Yes
75	MPP5	15735	-1.249	-0.3781	Yes
76	OCLN	16415	-1.472	-0.4051	Yes
77	HCLS1	16418	-1.473	-0.3955	Yes
78	F11R	16530	-1.515	-0.3915	Yes
79	AKT3	16533	-1.515	-0.3816	Yes
80	PRKCA	16539	-1.517	-0.3719	Yes
81	CLDN16	16616	-1.549	-0.3658	Yes
82	CLDN3	16650	-1.561	-0.3573	Yes
83	ACTN2	16842	-1.646	-0.3568	Yes
84	RRAS2	16898	-1.674	-0.3488	Yes
85	CSNK2A2	17557	-2.068	-0.3707	Yes
86	CDC42	17688	-2.168	-0.3634	Yes
87	CSDA	17738	-2.212	-0.3515	Yes
88	TJP2	18029	-2.555	-0.3504	Yes
89	ACTB	18073	-2.633	-0.3354	Yes
90	AKT2	18092	-2.672	-0.3188	Yes
91	CDK4	18355	-3.310	-0.3111	Yes
92	MAGI1	18422	-3.588	-0.2911	Yes
93	MYH10	18433	-3.640	-0.2677	Yes
94	INADL	18450	-3.746	-0.2439	Yes
95	EXOC4	18535	-4.671	-0.2177	Yes
96	PRKCH	18586	-6.190	-0.1797	Yes
97	MYLC2PL	18612	-11.925	-0.1025	Yes
98	AMOTL1	18616	-15.608	0.0000	Yes