Dataset | set04_DMproB_versus_LMproB |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_pos |
GeneSet | REACTOME_SIGNALING_IN_IMMUNE_SYSTEM |
Enrichment Score (ES) | 0.3522064 |
Normalized Enrichment Score (NES) | 1.5843759 |
Nominal p-value | 0.0 |
FDR q-value | 0.37119663 |
FWER p-Value | 1.0 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | CD86 | 35 | 5.307 | 0.0285 | Yes | ||
2 | ITGAL | 56 | 4.531 | 0.0534 | Yes | ||
3 | LBP | 98 | 4.049 | 0.0744 | Yes | ||
4 | TLR5 | 101 | 4.041 | 0.0974 | Yes | ||
5 | VCAM1 | 121 | 3.849 | 0.1185 | Yes | ||
6 | C3 | 216 | 3.318 | 0.1324 | Yes | ||
7 | LCP2 | 257 | 3.134 | 0.1482 | Yes | ||
8 | PAK1 | 273 | 3.072 | 0.1650 | Yes | ||
9 | FN1 | 371 | 2.825 | 0.1759 | Yes | ||
10 | RIPK2 | 386 | 2.807 | 0.1913 | Yes | ||
11 | CD14 | 390 | 2.801 | 0.2071 | Yes | ||
12 | FCER1G | 425 | 2.727 | 0.2209 | Yes | ||
13 | WAS | 438 | 2.700 | 0.2358 | Yes | ||
14 | LAT | 480 | 2.625 | 0.2486 | Yes | ||
15 | DOK2 | 523 | 2.555 | 0.2610 | Yes | ||
16 | SELL | 553 | 2.512 | 0.2738 | Yes | ||
17 | PTPN6 | 628 | 2.412 | 0.2836 | Yes | ||
18 | TYROBP | 827 | 2.160 | 0.2853 | Yes | ||
19 | ITGB2 | 1038 | 1.982 | 0.2853 | Yes | ||
20 | BCL10 | 1064 | 1.959 | 0.2951 | Yes | ||
21 | C1QB | 1146 | 1.900 | 0.3016 | Yes | ||
22 | PIK3CB | 1268 | 1.823 | 0.3055 | Yes | ||
23 | ATF2 | 1367 | 1.756 | 0.3103 | Yes | ||
24 | CD48 | 1534 | 1.658 | 0.3108 | Yes | ||
25 | PPIA | 1566 | 1.644 | 0.3186 | Yes | ||
26 | CSK | 1719 | 1.565 | 0.3193 | Yes | ||
27 | CD19 | 1745 | 1.554 | 0.3269 | Yes | ||
28 | MAP3K8 | 1750 | 1.552 | 0.3355 | Yes | ||
29 | TLR3 | 1755 | 1.549 | 0.3442 | Yes | ||
30 | TICAM2 | 1978 | 1.460 | 0.3406 | Yes | ||
31 | GRB14 | 2147 | 1.397 | 0.3395 | Yes | ||
32 | CD81 | 2191 | 1.378 | 0.3450 | Yes | ||
33 | JAM2 | 2317 | 1.329 | 0.3459 | Yes | ||
34 | C1QC | 2343 | 1.323 | 0.3521 | Yes | ||
35 | IFITM1 | 2478 | 1.280 | 0.3522 | Yes | ||
36 | FYB | 2640 | 1.227 | 0.3505 | No | ||
37 | TLR2 | 2914 | 1.148 | 0.3423 | No | ||
38 | PROC | 3059 | 1.107 | 0.3409 | No | ||
39 | CD40LG | 3108 | 1.097 | 0.3446 | No | ||
40 | IKBKB | 3468 | 0.998 | 0.3309 | No | ||
41 | THBD | 3477 | 0.996 | 0.3361 | No | ||
42 | C1R | 3506 | 0.989 | 0.3403 | No | ||
43 | B2M | 3515 | 0.987 | 0.3455 | No | ||
44 | ITGA5 | 3995 | 0.876 | 0.3246 | No | ||
45 | CHUK | 4007 | 0.874 | 0.3290 | No | ||
46 | OLR1 | 4037 | 0.865 | 0.3324 | No | ||
47 | C9 | 4056 | 0.861 | 0.3364 | No | ||
48 | CD3D | 4290 | 0.801 | 0.3284 | No | ||
49 | C6 | 4442 | 0.771 | 0.3246 | No | ||
50 | UBE2N | 4513 | 0.753 | 0.3251 | No | ||
51 | NFKB1 | 4547 | 0.748 | 0.3276 | No | ||
52 | TIRAP | 4811 | 0.694 | 0.3174 | No | ||
53 | SOS1 | 4827 | 0.690 | 0.3205 | No | ||
54 | CD47 | 4828 | 0.690 | 0.3245 | No | ||
55 | MAP3K7 | 4950 | 0.669 | 0.3218 | No | ||
56 | NFKBIA | 5386 | 0.585 | 0.3016 | No | ||
57 | ITGAM | 5569 | 0.552 | 0.2949 | No | ||
58 | C2 | 5838 | 0.500 | 0.2833 | No | ||
59 | GRAP2 | 6252 | 0.428 | 0.2634 | No | ||
60 | PIK3R1 | 6623 | 0.366 | 0.2455 | No | ||
61 | AKT1 | 7194 | 0.267 | 0.2161 | No | ||
62 | SLC16A3 | 7300 | 0.250 | 0.2119 | No | ||
63 | PIK3CA | 7419 | 0.232 | 0.2068 | No | ||
64 | MAP3K1 | 7470 | 0.224 | 0.2054 | No | ||
65 | CD3E | 7728 | 0.184 | 0.1926 | No | ||
66 | PDCD1 | 7730 | 0.184 | 0.1936 | No | ||
67 | ITGB3 | 7783 | 0.175 | 0.1918 | No | ||
68 | ITK | 7914 | 0.154 | 0.1856 | No | ||
69 | PTPRC | 8101 | 0.122 | 0.1762 | No | ||
70 | ITGAV | 8129 | 0.119 | 0.1755 | No | ||
71 | FCGR2B | 8183 | 0.112 | 0.1732 | No | ||
72 | CFD | 8394 | 0.081 | 0.1623 | No | ||
73 | CD160 | 8612 | 0.046 | 0.1509 | No | ||
74 | LYN | 8625 | 0.044 | 0.1505 | No | ||
75 | PTEN | 8691 | 0.035 | 0.1471 | No | ||
76 | APOB | 8878 | 0.002 | 0.1371 | No | ||
77 | TEK | 8932 | -0.006 | 0.1343 | No | ||
78 | TLR1 | 9068 | -0.027 | 0.1271 | No | ||
79 | CDH1 | 9082 | -0.029 | 0.1266 | No | ||
80 | NFKBIB | 9110 | -0.033 | 0.1253 | No | ||
81 | LCK | 9300 | -0.061 | 0.1154 | No | ||
82 | EEA1 | 9308 | -0.062 | 0.1154 | No | ||
83 | PLCG1 | 9400 | -0.078 | 0.1109 | No | ||
84 | CD2 | 9806 | -0.136 | 0.0898 | No | ||
85 | C8B | 9999 | -0.166 | 0.0804 | No | ||
86 | CD3G | 10693 | -0.275 | 0.0444 | No | ||
87 | PRKCQ | 11256 | -0.370 | 0.0161 | No | ||
88 | ENAH | 11757 | -0.449 | -0.0083 | No | ||
89 | RELA | 11802 | -0.455 | -0.0081 | No | ||
90 | C1QA | 12262 | -0.532 | -0.0299 | No | ||
91 | CD96 | 12296 | -0.537 | -0.0286 | No | ||
92 | ICOSLG | 12467 | -0.569 | -0.0345 | No | ||
93 | KIR3DL1 | 12996 | -0.667 | -0.0593 | No | ||
94 | MASP1 | 13012 | -0.670 | -0.0563 | No | ||
95 | MERTK | 13098 | -0.683 | -0.0570 | No | ||
96 | CRTAM | 13177 | -0.695 | -0.0572 | No | ||
97 | MAG | 13208 | -0.698 | -0.0548 | No | ||
98 | F2 | 13369 | -0.725 | -0.0593 | No | ||
99 | NCK1 | 13372 | -0.725 | -0.0553 | No | ||
100 | SPN | 13527 | -0.756 | -0.0593 | No | ||
101 | MBL2 | 13587 | -0.767 | -0.0581 | No | ||
102 | ITGAX | 13769 | -0.800 | -0.0633 | No | ||
103 | PPIL2 | 13935 | -0.829 | -0.0675 | No | ||
104 | CXADR | 13957 | -0.833 | -0.0638 | No | ||
105 | CD80 | 14126 | -0.867 | -0.0679 | No | ||
106 | CD226 | 14149 | -0.872 | -0.0641 | No | ||
107 | CAV1 | 14452 | -0.935 | -0.0751 | No | ||
108 | ITGA4 | 14550 | -0.957 | -0.0749 | No | ||
109 | ANGPT2 | 15063 | -1.073 | -0.0964 | No | ||
110 | SHC1 | 15121 | -1.088 | -0.0933 | No | ||
111 | ZAP70 | 15176 | -1.103 | -0.0899 | No | ||
112 | KRAS | 15643 | -1.222 | -0.1081 | No | ||
113 | PDPK1 | 15766 | -1.257 | -0.1075 | No | ||
114 | CD28 | 15825 | -1.274 | -0.1033 | No | ||
115 | IRF3 | 15966 | -1.316 | -0.1034 | No | ||
116 | BSG | 15986 | -1.322 | -0.0968 | No | ||
117 | MAP3K7IP1 | 16109 | -1.361 | -0.0956 | No | ||
118 | TLR4 | 16294 | -1.426 | -0.0974 | No | ||
119 | GRB7 | 16520 | -1.511 | -0.1009 | No | ||
120 | CTLA4 | 16536 | -1.516 | -0.0930 | No | ||
121 | CD4 | 16740 | -1.600 | -0.0948 | No | ||
122 | ITGB1 | 16759 | -1.607 | -0.0866 | No | ||
123 | CD200 | 16909 | -1.677 | -0.0851 | No | ||
124 | C1S | 16962 | -1.700 | -0.0781 | No | ||
125 | RIPK1 | 16985 | -1.715 | -0.0695 | No | ||
126 | LY86 | 17225 | -1.853 | -0.0718 | No | ||
127 | C8A | 17293 | -1.895 | -0.0646 | No | ||
128 | FYN | 17408 | -1.958 | -0.0595 | No | ||
129 | MAPK8 | 17416 | -1.961 | -0.0487 | No | ||
130 | ANGPT1 | 17808 | -2.275 | -0.0568 | No | ||
131 | PTPN11 | 17811 | -2.276 | -0.0439 | No | ||
132 | PIK3C3 | 17875 | -2.354 | -0.0338 | No | ||
133 | VAV1 | 17890 | -2.372 | -0.0209 | No | ||
134 | MAPK1 | 18210 | -2.885 | -0.0217 | No | ||
135 | JUN | 18337 | -3.236 | -0.0099 | No | ||
136 | GAS6 | 18510 | -4.358 | 0.0057 | No |