Details for gene set HSA04620_TOLL_LIKE_RECEPTOR_SIGNALING

Table: GSEA Results Summary

Dataset	set04_DMpreB_versus_WTpreB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	HSA04620_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.6065689
Normalized Enrichment Score (NES)	-1.822464
Nominal p-value	0.014842301
FDR q-value	0.35300595
FWER p-Value	0.932

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PIK3CB	780	7.582	-0.0203	No
2	MAPK12	1388	5.094	-0.0384	No
3	PIK3R3	1649	4.388	-0.0398	No
4	MAPK8	1673	4.351	-0.0285	No
5	MAP3K7	1717	4.246	-0.0185	No
6	MAPK11	1722	4.235	-0.0066	No
7	TICAM2	1726	4.224	0.0054	No
8	CD86	1882	3.880	0.0083	No
9	MYD88	2356	3.069	-0.0084	No
10	CXCL9	2926	2.453	-0.0321	No
11	AKT1	2954	2.432	-0.0265	No
12	TIRAP	3007	2.381	-0.0225	No
13	IFNA1	3323	2.127	-0.0334	No
14	CHUK	3524	1.992	-0.0384	No
15	IFNA7	4188	1.647	-0.0695	No
16	IRAK1	4314	1.586	-0.0717	No
17	TLR3	4876	1.365	-0.0980	No
18	IKBKB	5479	1.167	-0.1272	No
19	IFNA2	5761	1.074	-0.1392	No
20	CD14	6488	0.857	-0.1760	No
21	CCL4	6567	0.833	-0.1778	No
22	PIK3R2	7604	0.563	-0.2321	No
23	IFNB1	7668	0.547	-0.2339	No
24	IFNA6	8566	0.320	-0.2814	No
25	TRAF3	8599	0.313	-0.2822	No
26	TLR5	8633	0.305	-0.2831	No
27	MAP2K7	8699	0.290	-0.2858	No
28	IFNA14	8836	0.256	-0.2924	No
29	PIK3R5	8866	0.250	-0.2933	No
30	IL1B	9018	0.212	-0.3008	No
31	MAPK13	9080	0.198	-0.3035	No
32	TLR7	9146	0.184	-0.3065	No
33	CXCL10	9329	0.138	-0.3159	No
34	CCL3	9544	0.084	-0.3272	No
35	CCL5	9577	0.075	-0.3288	No
36	LBP	9762	0.033	-0.3386	No
37	NFKB2	9984	-0.028	-0.3505	No
38	IKBKE	10076	-0.051	-0.3552	No
39	CXCL11	10204	-0.079	-0.3618	No
40	TLR8	10360	-0.119	-0.3699	No
41	FOS	10490	-0.151	-0.3764	No
42	IL6	10537	-0.164	-0.3784	No
43	IL12B	10559	-0.169	-0.3791	No
44	CD80	10879	-0.257	-0.3955	No
45	IFNA13	12022	-0.564	-0.4556	No
46	MAP2K2	12431	-0.690	-0.4756	No
47	MAP2K1	12474	-0.704	-0.4759	No
48	IFNA4	12517	-0.717	-0.4761	No
49	IFNAR1	12692	-0.777	-0.4832	No
50	PIK3R1	12882	-0.833	-0.4910	No
51	MAPK10	13249	-0.964	-0.5080	No
52	IRF7	13372	-1.008	-0.5117	No
53	RIPK1	13643	-1.118	-0.5230	No
54	RAC1	13719	-1.142	-0.5238	No
55	TNF	13737	-1.150	-0.5214	No
56	MAP3K8	13974	-1.256	-0.5305	No
57	TLR4	14638	-1.600	-0.5617	No
58	FADD	14667	-1.621	-0.5585	No
59	LY96	14777	-1.674	-0.5596	No
60	TLR9	14809	-1.692	-0.5564	No
61	IFNA5	14974	-1.794	-0.5601	No
62	TBK1	15179	-1.931	-0.5655	No
63	MAP3K7IP1	15267	-1.988	-0.5645	No
64	PIK3CA	15572	-2.276	-0.5744	No
65	IRF5	15854	-2.562	-0.5822	No
66	MAP2K3	15856	-2.564	-0.5748	No
67	MAP2K4	16445	-3.446	-0.5966	Yes
68	IKBKG	16460	-3.469	-0.5874	Yes
69	CASP8	16569	-3.698	-0.5826	Yes
70	PIK3CD	16811	-4.218	-0.5834	Yes
71	JUN	16845	-4.286	-0.5729	Yes
72	MAPK14	16874	-4.333	-0.5619	Yes
73	MAP2K6	16991	-4.589	-0.5549	Yes
74	MAPK1	17264	-5.380	-0.5541	Yes
75	IRAK4	17330	-5.552	-0.5416	Yes
76	NFKB1	17383	-5.733	-0.5279	Yes
77	IL12A	17415	-5.813	-0.5128	Yes
78	RELA	17416	-5.813	-0.4961	Yes
79	AKT3	17454	-5.931	-0.4810	Yes
80	MAPK3	17495	-6.022	-0.4658	Yes
81	MAPK9	17613	-6.461	-0.4535	Yes
82	TOLLIP	17688	-6.703	-0.4382	Yes
83	IRF3	17778	-7.066	-0.4226	Yes
84	AKT2	17832	-7.269	-0.4046	Yes
85	NFKBIA	17884	-7.579	-0.3855	Yes
86	CD40	17926	-7.796	-0.3652	Yes
87	MAP3K7IP2	18062	-8.635	-0.3476	Yes
88	TRAF6	18077	-8.765	-0.3231	Yes
89	TLR2	18156	-9.445	-0.3001	Yes
90	IFNAR2	18260	-10.414	-0.2757	Yes
91	STAT1	18276	-10.570	-0.2461	Yes
92	PIK3CG	18341	-11.438	-0.2166	Yes
93	TLR1	18467	-14.848	-0.1805	Yes
94	SPP1	18561	-25.847	-0.1111	Yes
95	TLR6	18585	-39.562	0.0017	Yes