Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	set04_DMpreB_versus_WTpreB
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	0.617162
Normalized Enrichment Score (NES)	2.094684
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	POLR1B	14	28.191	0.0445	Yes
2	IMPDH2	58	18.288	0.0715	Yes
3	NME2	66	17.853	0.0997	Yes
4	ADK	79	16.597	0.1257	Yes
5	NME1	107	15.161	0.1485	Yes
6	PPAT	110	15.096	0.1727	Yes
7	POLD2	133	14.463	0.1947	Yes
8	GART	150	13.835	0.2160	Yes
9	AK2	153	13.651	0.2378	Yes
10	APRT	165	13.403	0.2587	Yes
11	ADSL	186	12.945	0.2784	Yes
12	POLR3H	187	12.912	0.2991	Yes
13	NME6	188	12.892	0.3197	Yes
14	ADA	218	12.375	0.3380	Yes
15	POLR1A	229	12.237	0.3571	Yes
16	NME4	274	11.661	0.3734	Yes
17	GMPS	291	11.420	0.3909	Yes
18	PKM2	293	11.356	0.4090	Yes
19	POLE3	316	11.119	0.4257	Yes
20	POLE	321	11.089	0.4433	Yes
21	NUDT5	337	10.876	0.4599	Yes
22	ATIC	370	10.520	0.4750	Yes
23	POLR2J	428	9.986	0.4880	Yes
24	POLR2H	482	9.582	0.5005	Yes
25	GUK1	500	9.459	0.5147	Yes
26	RFC5	570	8.951	0.5253	Yes
27	NUDT9	580	8.858	0.5391	Yes
28	ENTPD4	691	8.119	0.5461	Yes
29	PAICS	764	7.678	0.5546	Yes
30	AMPD2	789	7.536	0.5653	Yes
31	NUDT2	821	7.395	0.5755	Yes
32	NME7	991	6.502	0.5768	Yes
33	POLA2	997	6.482	0.5869	Yes
34	POLR2E	1117	5.985	0.5901	Yes
35	HPRT1	1215	5.665	0.5939	Yes
36	POLR2K	1286	5.454	0.5989	Yes
37	RRM1	1310	5.381	0.6063	Yes
38	PRPS1	1398	5.067	0.6097	Yes
39	POLR1D	1584	4.549	0.6070	Yes
40	POLR3A	1767	4.133	0.6038	Yes
41	POLR2A	1865	3.916	0.6048	Yes
42	PRIM1	1905	3.839	0.6089	Yes
43	POLD3	1927	3.807	0.6138	Yes
44	PDE8A	2020	3.635	0.6147	Yes
45	PNPT1	2111	3.476	0.6154	Yes
46	POLR2I	2179	3.359	0.6172	Yes
47	NT5E	2287	3.179	0.6165	No
48	AK3L1	2925	2.453	0.5860	No
49	ENTPD6	2988	2.398	0.5864	No
50	ECGF1	3175	2.229	0.5800	No
51	PRPS2	3314	2.133	0.5759	No
52	ADCY3	3667	1.902	0.5599	No
53	AK5	3947	1.764	0.5477	No
54	PDE10A	4002	1.738	0.5475	No
55	POLR3B	4006	1.736	0.5502	No
56	ENTPD1	4154	1.666	0.5449	No
57	PDE6G	4562	1.485	0.5252	No
58	NT5C3	5262	1.236	0.4894	No
59	NP	5532	1.149	0.4767	No
60	POLR2G	5592	1.130	0.4753	No
61	ENTPD8	6000	1.007	0.4549	No
62	GUCY2C	6424	0.875	0.4335	No
63	ADCY4	6491	0.857	0.4313	No
64	PDE8B	6560	0.835	0.4289	No
65	IMPDH1	6608	0.822	0.4277	No
66	AMPD3	6676	0.803	0.4254	No
67	ALLC	6730	0.792	0.4238	No
68	RRM2B	6818	0.770	0.4203	No
69	GUCY1A3	6903	0.750	0.4170	No
70	ENTPD3	7090	0.700	0.4080	No
71	GUCY2F	7328	0.635	0.3962	No
72	GUCY1A2	7796	0.514	0.3718	No
73	POLR3K	7847	0.497	0.3699	No
74	PDE5A	8051	0.447	0.3596	No
75	AK1	8345	0.376	0.3444	No
76	NPR1	9442	0.105	0.2853	No
77	XDH	9736	0.041	0.2695	No
78	POLA1	9763	0.033	0.2681	No
79	GDA	9794	0.025	0.2665	No
80	GUCY1B3	9806	0.023	0.2660	No
81	PDE9A	10135	-0.065	0.2483	No
82	ITPA	10186	-0.075	0.2458	No
83	ENPP1	10385	-0.125	0.2352	No
84	PDE3B	11038	-0.299	0.2005	No
85	ADCY8	11073	-0.313	0.1991	No
86	POLE2	11285	-0.370	0.1883	No
87	ADCY2	11292	-0.372	0.1886	No
88	PDE1A	11296	-0.373	0.1890	No
89	PDE2A	11481	-0.421	0.1797	No
90	AMPD1	11616	-0.461	0.1732	No
91	ENPP3	11818	-0.509	0.1632	No
92	PKLR	12376	-0.675	0.1341	No
93	PAPSS2	12432	-0.691	0.1323	No
94	PDE1C	12440	-0.694	0.1330	No
95	ADCY5	12461	-0.699	0.1330	No
96	PDE7B	13098	-0.911	0.1001	No
97	POLR2C	13132	-0.928	0.0998	No
98	ADCY6	13195	-0.946	0.0980	No
99	PDE4B	13854	-1.203	0.0643	No
100	POLR2B	13857	-1.203	0.0661	No
101	PDE6H	13866	-1.205	0.0676	No
102	ENTPD2	13926	-1.234	0.0664	No
103	FHIT	14059	-1.302	0.0614	No
104	CANT1	14089	-1.313	0.0619	No
105	NPR2	14283	-1.411	0.0537	No
106	NT5C1B	14636	-1.600	0.0372	No
107	PDE11A	14911	-1.752	0.0252	No
108	PDE4D	15754	-2.452	-0.0164	No
109	PAPSS1	15778	-2.478	-0.0136	No
110	NT5C	15902	-2.618	-0.0161	No
111	GMPR	15933	-2.663	-0.0135	No
112	POLE4	16044	-2.798	-0.0149	No
113	ZNRD1	16215	-3.030	-0.0193	No
114	GMPR2	16223	-3.045	-0.0147	No
115	PDE4C	16337	-3.245	-0.0157	No
116	ADCY9	16439	-3.439	-0.0156	No
117	PDE4A	16459	-3.468	-0.0111	No
118	NT5M	16618	-3.790	-0.0135	No
119	NT5C2	17007	-4.626	-0.0271	No
120	ENTPD5	17180	-5.116	-0.0282	No
121	RRM2	17403	-5.780	-0.0309	No
122	ADCY7	17418	-5.824	-0.0224	No
123	ADSSL1	17431	-5.873	-0.0136	No
124	POLD1	17475	-5.968	-0.0063	No
125	DCK	17594	-6.389	-0.0025	No
126	PDE7A	17899	-7.661	-0.0066	No
127	DGUOK	17948	-7.939	0.0035	No
128	PDE6D	18136	-9.289	0.0083	No
129	POLD4	18311	-10.982	0.0165	No