| GS follow link to MSigDB | GS DETAILS | SIZE | ES | NES | NOM p-val | FDR q-val | FWER p-val | RANK AT MAX | LEADING EDGE | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCI_BCR SIGNALING PATHWAY | Details ... | 64 | -0.72 | -2.09 | 0.000 | 0.499 | 0.386 | 2467 | tags=59%, list=13%, signal=68% |
| 2 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS III | Details ... | 30 | -0.76 | -1.94 | 0.004 | 0.970 | 0.848 | 1570 | tags=57%, list=8%, signal=62% |
| 3 | NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY | Details ... | 31 | -0.77 | -1.93 | 0.008 | 0.706 | 0.873 | 2762 | tags=58%, list=15%, signal=68% |
| 4 | NCI_OSTEOPONTIN-MEDIATED EVENTS | Details ... | 29 | -0.75 | -1.93 | 0.012 | 0.530 | 0.874 | 2353 | tags=55%, list=13%, signal=63% |
| 5 | BIOCARTA_BCR SIGNALING PATHWAY | Details ... | 29 | -0.75 | -1.93 | 0.010 | 0.432 | 0.877 | 2385 | tags=59%, list=13%, signal=67% |
| 6 | BIOCARTA_RAS-INDEPENDENT PATHWAY IN NK CELL-MEDIATED CYTOTOXICITY | Details ... | 19 | -0.81 | -1.90 | 0.008 | 0.455 | 0.931 | 1123 | tags=26%, list=6%, signal=28% |
| 7 | NCI_IL12 SIGNALING MEDIATED BY STAT4 | Details ... | 28 | -0.76 | -1.90 | 0.010 | 0.393 | 0.934 | 1773 | tags=36%, list=10%, signal=39% |
| 8 | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) | Details ... | 48 | -0.68 | -1.89 | 0.006 | 0.367 | 0.938 | 2467 | tags=44%, list=13%, signal=50% |
| 9 | NCI_IL12-MEDIATED SIGNALING EVENTS | Details ... | 104 | -0.62 | -1.89 | 0.002 | 0.327 | 0.938 | 2256 | tags=36%, list=12%, signal=40% |
| 10 | NCI_TCR SIGNALING IN NAÔVE CD8+ T CELLS | Details ... | 108 | -0.61 | -1.87 | 0.003 | 0.353 | 0.962 | 2625 | tags=37%, list=14%, signal=43% |
| 11 | BIOCARTA_FMLP INDUCED CHEMOKINE GENE EXPRESSION IN HMC-1 CELLS | Details ... | 28 | -0.73 | -1.85 | 0.019 | 0.364 | 0.979 | 2762 | tags=46%, list=15%, signal=54% |
| 12 | BIOCARTA_EICOSANOID METABOLISM | Details ... | 19 | -0.80 | -1.82 | 0.012 | 0.396 | 0.991 | 11 | tags=5%, list=0%, signal=5% |
| 13 | CELLMAP_KITRECEPTOR | Details ... | 49 | -0.67 | -1.81 | 0.018 | 0.381 | 0.992 | 2010 | tags=37%, list=11%, signal=41% |
| 14 | NCI_TCR SIGNALING IN NAÔVE CD4+ T CELLS | Details ... | 118 | -0.58 | -1.81 | 0.007 | 0.362 | 0.995 | 2625 | tags=38%, list=14%, signal=44% |
| 15 | INOH_NOTCH SECRETORY PATHWAY (MAMMAL) | Details ... | 22 | -0.75 | -1.80 | 0.016 | 0.350 | 0.996 | 2265 | tags=55%, list=12%, signal=62% |
| 16 | INOH_B CELL RECEPTOR SIGNALING PATHWAY | Details ... | 68 | -0.62 | -1.80 | 0.009 | 0.334 | 0.996 | 2385 | tags=35%, list=13%, signal=40% |
| 17 | INOH_MAMMALIAN NOTCH SIGNALING PATHWAY | Details ... | 22 | -0.75 | -1.80 | 0.021 | 0.315 | 0.996 | 2265 | tags=55%, list=12%, signal=62% |
| 18 | NCI_IL27-MEDIATED SIGNALING EVENTS | Details ... | 26 | -0.72 | -1.80 | 0.025 | 0.299 | 0.996 | 2187 | tags=35%, list=12%, signal=39% |
| 19 | BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY | Details ... | 45 | -0.66 | -1.79 | 0.014 | 0.294 | 0.996 | 3742 | tags=56%, list=20%, signal=69% |
| 20 | INOH_CANONICAL NOTCH SIGNALING PATHWAY | Details ... | 26 | -0.69 | -1.79 | 0.016 | 0.287 | 0.996 | 2937 | tags=50%, list=16%, signal=59% |
| 21 | NETPATH_IL2 | 61 | -0.62 | -1.79 | 0.020 | 0.275 | 0.996 | 2385 | tags=39%, list=13%, signal=45% | |
| 22 | NCI_IL1-MEDIATED SIGNALING EVENTS | 187 | -0.54 | -1.79 | 0.002 | 0.262 | 0.996 | 2762 | tags=38%, list=15%, signal=44% | |
| 23 | NETPATH_IL-7 | 16 | -0.79 | -1.78 | 0.012 | 0.260 | 0.996 | 604 | tags=25%, list=3%, signal=26% | |
| 24 | NETPATH_THROMBOPOIETIN | 40 | -0.69 | -1.78 | 0.021 | 0.252 | 0.996 | 2385 | tags=43%, list=13%, signal=49% | |
| 25 | BIOCARTA_P38 MAPK SIGNALING PATHWAY | 28 | -0.71 | -1.78 | 0.013 | 0.246 | 0.996 | 2307 | tags=57%, list=12%, signal=65% | |
| 26 | NCI_DOWNSTREAM SIGNALING IN NAÔVE CD8+ T CELLS | 48 | -0.64 | -1.78 | 0.006 | 0.239 | 0.997 | 2544 | tags=33%, list=14%, signal=39% | |
| 27 | NETPATH_BCR | 115 | -0.57 | -1.76 | 0.007 | 0.246 | 1.000 | 2504 | tags=52%, list=13%, signal=60% | |
| 28 | NCI_EPO SIGNALING PATHWAY | 32 | -0.68 | -1.76 | 0.024 | 0.240 | 1.000 | 1960 | tags=41%, list=11%, signal=45% | |
| 29 | NCI_IL6-MEDIATED SIGNALING EVENTS | 44 | -0.66 | -1.75 | 0.024 | 0.246 | 1.000 | 3046 | tags=48%, list=16%, signal=57% | |
| 30 | NCI_IL4-MEDIATED SIGNALING EVENTS | 58 | -0.61 | -1.75 | 0.032 | 0.243 | 1.000 | 1988 | tags=29%, list=11%, signal=33% | |
| 31 | NETPATH_IFN-ALPHA | 43 | -0.64 | -1.74 | 0.025 | 0.247 | 1.000 | 2256 | tags=47%, list=12%, signal=53% | |
| 32 | NETPATH_CD40 | 30 | -0.67 | -1.73 | 0.024 | 0.250 | 1.000 | 2955 | tags=40%, list=16%, signal=47% | |
| 33 | NETPATH_IL6 | 57 | -0.62 | -1.72 | 0.026 | 0.250 | 1.000 | 2237 | tags=46%, list=12%, signal=52% | |
| 34 | BIOCARTA_ANGIOTENSIN II MEDIATED ACTIVATION OF JNK PATHWAY VIA PYK2 DEPENDENT SIGNALING | 31 | -0.68 | -1.72 | 0.020 | 0.243 | 1.000 | 3069 | tags=52%, list=16%, signal=62% | |
| 35 | NCI_REGULATION OF P38-ALPHA AND P38-BETA | 142 | -0.54 | -1.72 | 0.005 | 0.241 | 1.000 | 2762 | tags=38%, list=15%, signal=44% | |
| 36 | NETPATH_IL5 | 31 | -0.68 | -1.71 | 0.036 | 0.242 | 1.000 | 2385 | tags=55%, list=13%, signal=63% | |
| 37 | INOH_NOTCH SECRETORY PATHWAY | 26 | -0.69 | -1.71 | 0.020 | 0.241 | 1.000 | 2937 | tags=50%, list=16%, signal=59% | |
| 38 | NCI_FGF SIGNALING PATHWAY | 43 | -0.63 | -1.71 | 0.020 | 0.239 | 1.000 | 1804 | tags=23%, list=10%, signal=26% | |
| 39 | BIOCARTA_EFFECTS OF CALCINEURIN IN KERATINOCYTE DIFFERENTIATION | 12 | -0.80 | -1.70 | 0.025 | 0.235 | 1.000 | 2289 | tags=58%, list=12%, signal=66% | |
| 40 | NCI_IL2-MEDIATED SIGNALING EVENTS | 112 | -0.54 | -1.69 | 0.018 | 0.251 | 1.000 | 2625 | tags=36%, list=14%, signal=41% | |
| 41 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | 12 | -0.79 | -1.69 | 0.028 | 0.246 | 1.000 | 2820 | tags=75%, list=15%, signal=88% | |
| 42 | NETPATH_EPO | 39 | -0.63 | -1.68 | 0.027 | 0.248 | 1.000 | 3094 | tags=44%, list=17%, signal=52% | |
| 43 | NCI_IFN-GAMMA PATHWAY | 331 | -0.49 | -1.68 | 0.000 | 0.243 | 1.000 | 2050 | tags=28%, list=11%, signal=31% | |
| 44 | BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY | 24 | -0.70 | -1.68 | 0.028 | 0.239 | 1.000 | 3075 | tags=63%, list=17%, signal=75% | |
| 45 | BIOCARTA_BIOACTIVE PEPTIDE INDUCED SIGNALING PATHWAY | 32 | -0.65 | -1.68 | 0.035 | 0.234 | 1.000 | 2180 | tags=38%, list=12%, signal=42% | |
| 46 | NETPATH_TCR | 105 | -0.53 | -1.68 | 0.014 | 0.231 | 1.000 | 3094 | tags=38%, list=17%, signal=45% | |
| 47 | NCI_BMP RECEPTOR SIGNALING | 196 | -0.51 | -1.67 | 0.005 | 0.228 | 1.000 | 2762 | tags=35%, list=15%, signal=41% | |
| 48 | REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING | 20 | -0.71 | -1.67 | 0.030 | 0.225 | 1.000 | 3046 | tags=55%, list=16%, signal=66% | |
| 49 | INOH_GENE EXPRESSION OF SOCS BY STAT DIMER | 13 | -0.79 | -1.67 | 0.022 | 0.221 | 1.000 | 879 | tags=38%, list=5%, signal=40% | |
| 50 | NCI_IL23-MEDIATED SIGNALING EVENTS | 65 | -0.59 | -1.67 | 0.033 | 0.218 | 1.000 | 2256 | tags=31%, list=12%, signal=35% | |
| 51 | BIOCARTA_HUMAN CYTOMEGALOVIRUS AND MAP KINASE PATHWAYS | 16 | -0.74 | -1.66 | 0.022 | 0.223 | 1.000 | 3046 | tags=69%, list=16%, signal=82% | |
| 52 | NETPATH_IL4 | 42 | -0.61 | -1.66 | 0.032 | 0.223 | 1.000 | 2237 | tags=50%, list=12%, signal=57% | |
| 53 | BIOCARTA_PHOSPHORYLATION OF MEK1 BY CDK5/P35 DOWN REGULATES THE MAP KINASE PATHWAY | 13 | -0.75 | -1.65 | 0.023 | 0.229 | 1.000 | 2385 | tags=46%, list=13%, signal=53% | |
| 54 | BIOCARTA_LINKS BETWEEN PYK2 AND MAP KINASES | 25 | -0.67 | -1.65 | 0.046 | 0.226 | 1.000 | 2762 | tags=52%, list=15%, signal=61% | |
| 55 | NCI_S1P3 PATHWAY | 24 | -0.68 | -1.65 | 0.045 | 0.222 | 1.000 | 2289 | tags=42%, list=12%, signal=47% | |
| 56 | NCI_CLASS I PI3K SIGNALING EVENTS | 217 | -0.49 | -1.64 | 0.005 | 0.225 | 1.000 | 2285 | tags=35%, list=12%, signal=40% | |
| 57 | NCI_TRK RECEPTOR SIGNALING MEDIATED BY PI3K AND PLC-GAMMA | 56 | -0.57 | -1.64 | 0.025 | 0.227 | 1.000 | 3149 | tags=46%, list=17%, signal=56% | |
| 58 | NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY | 32 | -0.64 | -1.64 | 0.035 | 0.223 | 1.000 | 2544 | tags=41%, list=14%, signal=47% | |
| 59 | BIOCARTA_CHAPERONES MODULATE INTERFERON SIGNALING PATHWAY | 16 | -0.72 | -1.63 | 0.035 | 0.228 | 1.000 | 2158 | tags=50%, list=12%, signal=57% | |
| 60 | BIOCARTA_FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS | 27 | -0.66 | -1.63 | 0.042 | 0.229 | 1.000 | 2385 | tags=37%, list=13%, signal=42% | |
| 61 | NCI_P38 MAPK SIGNALING PATHWAY | 162 | -0.50 | -1.62 | 0.007 | 0.229 | 1.000 | 2762 | tags=36%, list=15%, signal=42% | |
| 62 | NCI_GLYPICAN 1 NETWORK | 380 | -0.46 | -1.62 | 0.000 | 0.227 | 1.000 | 2285 | tags=31%, list=12%, signal=35% | |
| 63 | INOH_IKK-NF-KAPPAB CASCADE | 12 | -0.75 | -1.62 | 0.041 | 0.227 | 1.000 | 2237 | tags=50%, list=12%, signal=57% | |
| 64 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS I | 90 | -0.53 | -1.61 | 0.021 | 0.227 | 1.000 | 1570 | tags=32%, list=8%, signal=35% | |
| 65 | BIOCARTA_NFKB ACTIVATION BY NONTYPEABLE HEMOPHILUS INFLUENZAE | 26 | -0.64 | -1.61 | 0.037 | 0.231 | 1.000 | 2762 | tags=58%, list=15%, signal=68% | |
| 66 | BIOCARTA_GROWTH HORMONE SIGNALING PATHWAY | 17 | -0.70 | -1.61 | 0.039 | 0.229 | 1.000 | 1129 | tags=24%, list=6%, signal=25% | |
| 67 | INOH_T CELL RECEPTOR SIGNALING PATHWAY | 51 | -0.57 | -1.60 | 0.045 | 0.230 | 1.000 | 2385 | tags=43%, list=13%, signal=49% | |
| 68 | NCI_GLYPICAN PATHWAY | 416 | -0.45 | -1.60 | 0.001 | 0.233 | 1.000 | 2285 | tags=29%, list=12%, signal=33% | |
| 69 | BIOCARTA_KERATINOCYTE DIFFERENTIATION | 51 | -0.57 | -1.59 | 0.041 | 0.232 | 1.000 | 3069 | tags=41%, list=16%, signal=49% | |
| 70 | BIOCARTA_TOLL-LIKE RECEPTOR PATHWAY | 34 | -0.61 | -1.59 | 0.034 | 0.236 | 1.000 | 2173 | tags=41%, list=12%, signal=47% | |
| 71 | BIOCARTA_ROLE OF EGF RECEPTOR TRANSACTIVATION BY GPCRS IN CARDIAC HYPERTROPHY | 32 | -0.61 | -1.59 | 0.032 | 0.233 | 1.000 | 2385 | tags=34%, list=13%, signal=39% | |
| 72 | BIOCARTA_CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES | 15 | -0.69 | -1.59 | 0.051 | 0.230 | 1.000 | 2385 | tags=47%, list=13%, signal=53% | |
| 73 | BIOCARTA_ROLE OF ERK5 IN NEURONAL SURVIVAL PATHWAY | 24 | -0.64 | -1.58 | 0.048 | 0.230 | 1.000 | 3046 | tags=42%, list=16%, signal=50% | |
| 74 | NCI_S1P1 PATHWAY | 64 | -0.56 | -1.58 | 0.028 | 0.227 | 1.000 | 3664 | tags=41%, list=20%, signal=50% | |
| 75 | NCI_SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA | 46 | -0.58 | -1.58 | 0.057 | 0.230 | 1.000 | 3152 | tags=50%, list=17%, signal=60% | |
| 76 | BIOCARTA_MAPKINASE SIGNALING PATHWAY | 54 | -0.56 | -1.58 | 0.046 | 0.227 | 1.000 | 2762 | tags=39%, list=15%, signal=46% | |
| 77 | NCI_REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2/3 SIGNALING | 258 | -0.46 | -1.58 | 0.010 | 0.226 | 1.000 | 2237 | tags=29%, list=12%, signal=33% | |
| 78 | NCI_THROMBOXANE A2 RECEPTOR SIGNALING | 50 | -0.58 | -1.58 | 0.036 | 0.225 | 1.000 | 3629 | tags=44%, list=19%, signal=55% | |
| 79 | BIOCARTA_IL 3 SIGNALING PATHWAY | 11 | -0.74 | -1.57 | 0.045 | 0.227 | 1.000 | 1129 | tags=27%, list=6%, signal=29% | |
| 80 | NCI_P75(NTR)-MEDIATED SIGNALING | 157 | -0.49 | -1.57 | 0.022 | 0.224 | 1.000 | 3149 | tags=41%, list=17%, signal=49% | |
| 81 | NCI_TGF-BETA RECEPTOR SIGNALING | 258 | -0.46 | -1.57 | 0.010 | 0.223 | 1.000 | 2237 | tags=29%, list=12%, signal=33% | |
| 82 | NCI_TNF RECEPTOR SIGNALING PATHWAY | 244 | -0.47 | -1.57 | 0.015 | 0.221 | 1.000 | 2762 | tags=35%, list=15%, signal=41% | |
| 83 | NCI_REGULATION OF NUCLEAR SMAD2/3 SIGNALING | 258 | -0.46 | -1.57 | 0.005 | 0.220 | 1.000 | 2237 | tags=29%, list=12%, signal=33% | |
| 84 | INOH_RAF ACTIVATION SIGNALING (THROUGH GRB2 AND SOS) | 11 | -0.74 | -1.57 | 0.052 | 0.218 | 1.000 | 2385 | tags=45%, list=13%, signal=52% | |
| 85 | NCI_PLASMA MEMBRANE ESTROGEN RECEPTOR SIGNALING | 266 | -0.45 | -1.57 | 0.015 | 0.217 | 1.000 | 3407 | tags=36%, list=18%, signal=44% | |
| 86 | NCI_CELLULAR ROLES OF ANTHRAX TOXIN | 15 | -0.70 | -1.56 | 0.041 | 0.216 | 1.000 | 2762 | tags=40%, list=15%, signal=47% | |
| 87 | BIOCARTA_TPO SIGNALING PATHWAY | 22 | -0.64 | -1.56 | 0.035 | 0.213 | 1.000 | 2385 | tags=36%, list=13%, signal=42% | |
| 88 | NCI_AURORA A SIGNALING | 58 | -0.56 | -1.56 | 0.035 | 0.212 | 1.000 | 2256 | tags=36%, list=12%, signal=41% | |
| 89 | NCI_INTEGRINS IN ANGIOGENESIS | 63 | -0.54 | -1.56 | 0.043 | 0.213 | 1.000 | 2067 | tags=35%, list=11%, signal=39% | |
| 90 | NCI_CANONICAL NF-KAPPAB PATHWAY | 35 | -0.58 | -1.55 | 0.044 | 0.218 | 1.000 | 3046 | tags=49%, list=16%, signal=58% | |
| 91 | REACTOME_GRB2_EVENTS_IN_EGFR_SIGNALING | 10 | -0.76 | -1.55 | 0.039 | 0.217 | 1.000 | 3149 | tags=60%, list=17%, signal=72% | |
| 92 | NCI_EPHA FORWARD SIGNALING | 30 | -0.61 | -1.55 | 0.059 | 0.216 | 1.000 | 3855 | tags=47%, list=21%, signal=59% | |
| 93 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | 13 | -0.71 | -1.54 | 0.043 | 0.219 | 1.000 | 941 | tags=38%, list=5%, signal=40% | |
| 94 | NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY | 119 | -0.50 | -1.54 | 0.026 | 0.219 | 1.000 | 2385 | tags=34%, list=13%, signal=38% | |
| 95 | REACTOME_SIGNALING_BY_EGFR | 27 | -0.60 | -1.54 | 0.059 | 0.218 | 1.000 | 3149 | tags=41%, list=17%, signal=49% | |
| 96 | NCI_S1P2 PATHWAY | 21 | -0.64 | -1.54 | 0.066 | 0.219 | 1.000 | 3380 | tags=48%, list=18%, signal=58% | |
| 97 | BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE | 13 | -0.71 | -1.53 | 0.059 | 0.222 | 1.000 | 3545 | tags=62%, list=19%, signal=76% | |
| 98 | BIOCARTA_IL12 AND STAT4 DEPENDENT SIGNALING PATHWAY IN TH1 DEVELOPMENT | 15 | -0.67 | -1.53 | 0.048 | 0.222 | 1.000 | 2187 | tags=53%, list=12%, signal=60% | |
| 99 | NCI_CALCINEURIN-REGULATED NFAT-DEPENDENT TRANSCRIPTION IN LYMPHOCYTES | 43 | -0.57 | -1.53 | 0.061 | 0.226 | 1.000 | 2050 | tags=28%, list=11%, signal=31% | |
| 100 | BIOCARTA_EPO SIGNALING PATHWAY | 11 | -0.72 | -1.52 | 0.035 | 0.226 | 1.000 | 1129 | tags=27%, list=6%, signal=29% | |
| 101 | BIOCARTA_IL22 SOLUBLE RECEPTOR SIGNALING PATHWAY | 11 | -0.73 | -1.52 | 0.055 | 0.229 | 1.000 | 2187 | tags=36%, list=12%, signal=41% | |
| 102 | BIOCARTA_TNFR2 SIGNALING PATHWAY | 12 | -0.72 | -1.52 | 0.060 | 0.230 | 1.000 | 3918 | tags=67%, list=21%, signal=84% | |
| 103 | BIOCARTA_CONTROL OF SKELETAL MYOGENESIS BY HDAC AND CALCIUM/CALMODULIN-DEPENDENT KINASE (CAMK) | 18 | -0.65 | -1.51 | 0.078 | 0.230 | 1.000 | 1744 | tags=39%, list=9%, signal=43% | |
| 104 | BIOCARTA_REGULATION OF PGC-1A | 18 | -0.66 | -1.51 | 0.065 | 0.232 | 1.000 | 3984 | tags=61%, list=21%, signal=78% | |
| 105 | NCI_NEUROTROPHIC FACTOR-MEDIATED TRK RECEPTOR SIGNALING | 88 | -0.50 | -1.51 | 0.037 | 0.230 | 1.000 | 3149 | tags=39%, list=17%, signal=46% | |
| 106 | INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING) | 16 | -0.66 | -1.51 | 0.047 | 0.229 | 1.000 | 1167 | tags=25%, list=6%, signal=27% | |
| 107 | NCI_PDGFR-BETA SIGNALING PATHWAY | 51 | -0.56 | -1.51 | 0.064 | 0.228 | 1.000 | 3664 | tags=41%, list=20%, signal=51% | |
| 108 | INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING) | 16 | -0.66 | -1.51 | 0.067 | 0.227 | 1.000 | 1167 | tags=25%, list=6%, signal=27% | |
| 109 | BIOCARTA_EGF SIGNALING PATHWAY | 18 | -0.64 | -1.50 | 0.067 | 0.227 | 1.000 | 3664 | tags=56%, list=20%, signal=69% | |
| 110 | REACTOME_SHC_EVENTS_IN_EGFR_SIGNALING | 11 | -0.72 | -1.50 | 0.077 | 0.232 | 1.000 | 3149 | tags=55%, list=17%, signal=66% | |
| 111 | INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING) | 17 | -0.64 | -1.49 | 0.059 | 0.234 | 1.000 | 2612 | tags=35%, list=14%, signal=41% | |
| 112 | NETPATH_BDNF | 31 | -0.58 | -1.49 | 0.068 | 0.233 | 1.000 | 3240 | tags=39%, list=17%, signal=47% | |
| 113 | REACTOME_SHC_RELATED_EVENTS | 10 | -0.71 | -1.49 | 0.081 | 0.237 | 1.000 | 3149 | tags=50%, list=17%, signal=60% | |
| 114 | BIOCARTA_PDGF SIGNALING PATHWAY | 24 | -0.61 | -1.49 | 0.075 | 0.236 | 1.000 | 3859 | tags=54%, list=21%, signal=68% | |
| 115 | BIOCARTA_SIGNALING PATHWAY FROM G-PROTEIN FAMILIES | 23 | -0.61 | -1.48 | 0.095 | 0.238 | 1.000 | 2385 | tags=48%, list=13%, signal=55% | |
| 116 | REACTOME_PLATELET_ACTIVATION_TRIGGERS | 24 | -0.60 | -1.48 | 0.081 | 0.236 | 1.000 | 2289 | tags=42%, list=12%, signal=47% | |
| 117 | BIOCARTA_TRANSCRIPTION FACTOR CREB AND ITS EXTRACELLULAR SIGNALS | 25 | -0.59 | -1.48 | 0.065 | 0.242 | 1.000 | 2074 | tags=44%, list=11%, signal=49% | |
| 118 | NCI_IL2 SIGNALING EVENTS MEDIATED BY PI3K | 67 | -0.50 | -1.47 | 0.048 | 0.244 | 1.000 | 2256 | tags=31%, list=12%, signal=36% | |
| 119 | INOH_PHOSPHOLIPASE C GAMMA SIGNALING | 48 | -0.54 | -1.47 | 0.077 | 0.247 | 1.000 | 2385 | tags=42%, list=13%, signal=48% | |
| 120 | HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS I | 10 | -0.70 | -1.46 | 0.068 | 0.249 | 1.000 | 889 | tags=20%, list=5%, signal=21% | |
| 121 | BIOCARTA_CALCIUM SIGNALING BY HBX OF HEPATITIS B VIRUS | 15 | -0.66 | -1.46 | 0.076 | 0.249 | 1.000 | 2385 | tags=40%, list=13%, signal=46% | |
| 122 | INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING) | 16 | -0.66 | -1.46 | 0.082 | 0.252 | 1.000 | 1167 | tags=25%, list=6%, signal=27% | |
| 123 | NCI_TRAIL SIGNALING PATHWAY | 275 | -0.43 | -1.46 | 0.023 | 0.250 | 1.000 | 2544 | tags=34%, list=14%, signal=39% | |
| 124 | BIOCARTA_TGF BETA SIGNALING PATHWAY | 19 | -0.61 | -1.46 | 0.095 | 0.251 | 1.000 | 1843 | tags=37%, list=10%, signal=41% | |
| 125 | BIOCARTA_INHIBITION OF CELLULAR PROLIFERATION BY GLEEVEC | 22 | -0.61 | -1.45 | 0.089 | 0.256 | 1.000 | 2385 | tags=45%, list=13%, signal=52% | |
| 126 | NCI_SIGNALING BY AURORA KINASES | 85 | -0.48 | -1.45 | 0.044 | 0.255 | 1.000 | 2256 | tags=29%, list=12%, signal=33% | |
| 127 | BIOCARTA_NFAT AND HYPERTROPHY OF THE HEART | 42 | -0.54 | -1.45 | 0.084 | 0.257 | 1.000 | 2263 | tags=26%, list=12%, signal=30% | |
| 128 | BIOCARTA_REGULATION OF TRANSCRIPTIONAL ACTIVITY BY PML | 10 | -0.70 | -1.45 | 0.082 | 0.256 | 1.000 | 2286 | tags=50%, list=12%, signal=57% | |
| 129 | CELLMAP_EGFR1 | 117 | -0.47 | -1.45 | 0.048 | 0.254 | 1.000 | 2252 | tags=28%, list=12%, signal=32% | |
| 130 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (MAMMAL) | 28 | -0.56 | -1.45 | 0.057 | 0.252 | 1.000 | 3294 | tags=32%, list=18%, signal=39% | |
| 131 | REACTOME_SIGNALING_IN_IMMUNE_SYSTEM | 136 | -0.46 | -1.44 | 0.054 | 0.250 | 1.000 | 2354 | tags=21%, list=13%, signal=24% | |
| 132 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (CANONICAL) | 31 | -0.56 | -1.44 | 0.094 | 0.250 | 1.000 | 3294 | tags=35%, list=18%, signal=43% | |
| 133 | BIOCARTA_PKC-CATALYZED PHOSPHORYLATION OF INHIBITORY PHOSPHOPROTEIN OF MYOSIN PHOSPHATASE | 18 | -0.63 | -1.44 | 0.088 | 0.253 | 1.000 | 2562 | tags=33%, list=14%, signal=39% | |
| 134 | NCI_FC-EPSILON RECEPTOR I SIGNALING IN MAST CELLS | 56 | -0.51 | -1.44 | 0.080 | 0.254 | 1.000 | 2385 | tags=36%, list=13%, signal=41% | |
| 135 | REACTOME_TOLL_RECEPTOR_CASCADES | 26 | -0.57 | -1.43 | 0.097 | 0.256 | 1.000 | 1773 | tags=35%, list=10%, signal=38% | |
| 136 | BIOCARTA_SIGNAL TRANSDUCTION THROUGH IL1R | 34 | -0.55 | -1.43 | 0.083 | 0.258 | 1.000 | 2762 | tags=44%, list=15%, signal=52% | |
| 137 | NCI_ATYPICAL NF-KAPPAB PATHWAY | 14 | -0.64 | -1.43 | 0.089 | 0.258 | 1.000 | 3407 | tags=57%, list=18%, signal=70% | |
| 138 | NCI_S1P4 PATHWAY | 11 | -0.68 | -1.42 | 0.096 | 0.262 | 1.000 | 1464 | tags=36%, list=8%, signal=39% | |
| 139 | BIOCARTA_ROLES OF FL ARRESTIN DEPENDENT RECRUITMENT OF SRC KINASES IN GPCR SIGNALING | 32 | -0.56 | -1.41 | 0.094 | 0.276 | 1.000 | 2700 | tags=28%, list=15%, signal=33% | |
| 140 | BIOCARTA_OXIDATIVE STRESS INDUCED GENE EXPRESSION VIA NRF2 | 16 | -0.62 | -1.40 | 0.110 | 0.281 | 1.000 | 3414 | tags=63%, list=18%, signal=76% | |
| 141 | BIOCARTA_ALK IN CARDIAC MYOCYTES | 27 | -0.56 | -1.40 | 0.117 | 0.282 | 1.000 | 1732 | tags=33%, list=9%, signal=37% | |
| 142 | NCI_LPA RECEPTOR MEDIATED EVENTS | 91 | -0.45 | -1.40 | 0.060 | 0.281 | 1.000 | 2289 | tags=32%, list=12%, signal=36% | |
| 143 | NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY | 22 | -0.57 | -1.40 | 0.094 | 0.281 | 1.000 | 2544 | tags=36%, list=14%, signal=42% | |
| 144 | NCI_ROLE OF CALCINEURIN-DEPENDENT NFAT SIGNALING IN LYMPHOCYTES | 78 | -0.48 | -1.39 | 0.079 | 0.286 | 1.000 | 2237 | tags=28%, list=12%, signal=32% | |
| 145 | REACTOME_SIGNALLING_BY_NGF | 61 | -0.49 | -1.39 | 0.075 | 0.293 | 1.000 | 1708 | tags=30%, list=9%, signal=32% | |
| 146 | HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS II | 22 | -0.57 | -1.39 | 0.107 | 0.291 | 1.000 | 3187 | tags=32%, list=17%, signal=38% | |
| 147 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH LPS, TLR4, MYD88, IRAK, TAK1 AND IKK-NF-KAPPAB CASCADE)(CANONICAL) | 22 | -0.59 | -1.39 | 0.104 | 0.292 | 1.000 | 2694 | tags=50%, list=14%, signal=58% | |
| 148 | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY | 22 | -0.55 | -1.38 | 0.120 | 0.293 | 1.000 | 490 | tags=14%, list=3%, signal=14% | |
| 149 | REACTOME_TCR_SIGNALING | 32 | -0.54 | -1.38 | 0.119 | 0.293 | 1.000 | 2194 | tags=31%, list=12%, signal=35% | |
| 150 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | 17 | -0.60 | -1.38 | 0.110 | 0.292 | 1.000 | 2987 | tags=47%, list=16%, signal=56% | |
| 151 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (XENOPUS) | 16 | -0.59 | -1.38 | 0.123 | 0.294 | 1.000 | 1922 | tags=25%, list=10%, signal=28% | |
| 152 | NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS | 68 | -0.48 | -1.38 | 0.095 | 0.293 | 1.000 | 1804 | tags=21%, list=10%, signal=23% | |
| 153 | INOH_IL-1_SIGNALING(THROUGH_IKK-NFKB_CASCADE)(CANONICAL) | 23 | -0.57 | -1.37 | 0.123 | 0.297 | 1.000 | 2694 | tags=48%, list=14%, signal=56% | |
| 154 | BIOCARTA_RAC1 CELL MOTILITY SIGNALING PATHWAY | 29 | -0.54 | -1.37 | 0.092 | 0.297 | 1.000 | 3046 | tags=38%, list=16%, signal=45% | |
| 155 | NCI_REGULATION OF ANDROGEN RECEPTOR ACTIVITY | 80 | -0.47 | -1.37 | 0.092 | 0.296 | 1.000 | 2439 | tags=36%, list=13%, signal=42% | |
| 156 | NETPATH_IL9 | 11 | -0.65 | -1.37 | 0.148 | 0.298 | 1.000 | 1129 | tags=18%, list=6%, signal=19% | |
| 157 | REACTOME_SPHINGOLIPID_METABOLISM | 10 | -0.66 | -1.37 | 0.123 | 0.297 | 1.000 | 3758 | tags=60%, list=20%, signal=75% | |
| 158 | REACTOME_SEMAPHORIN_INTERACTIONS | 30 | -0.53 | -1.36 | 0.088 | 0.302 | 1.000 | 2820 | tags=40%, list=15%, signal=47% | |
| 159 | BIOCARTA_ERK1/ERK2 MAPK SIGNALING PATHWAY | 20 | -0.58 | -1.36 | 0.128 | 0.301 | 1.000 | 2385 | tags=35%, list=13%, signal=40% | |
| 160 | BIOCARTA_BONE REMODELING | 15 | -0.60 | -1.36 | 0.137 | 0.300 | 1.000 | 2158 | tags=33%, list=12%, signal=38% | |
| 161 | REACTOME_SIGNALLING_TO_RAS | 12 | -0.62 | -1.36 | 0.129 | 0.299 | 1.000 | 3149 | tags=50%, list=17%, signal=60% | |
| 162 | NCI_ENDOTHELINS | 147 | -0.43 | -1.36 | 0.069 | 0.297 | 1.000 | 3149 | tags=31%, list=17%, signal=37% | |
| 163 | NCI_JNK SIGNALING IN THE CD4+ TCR PATHWAY | 33 | -0.53 | -1.35 | 0.122 | 0.302 | 1.000 | 2544 | tags=39%, list=14%, signal=46% | |
| 164 | NCI_AMB2 INTEGRIN SIGNALING | 48 | -0.49 | -1.35 | 0.107 | 0.301 | 1.000 | 3407 | tags=29%, list=18%, signal=36% | |
| 165 | BIOCARTA_ROLE OF FL-ARRESTINS IN THE ACTIVATION AND TARGETING OF MAP KINASES | 28 | -0.53 | -1.35 | 0.128 | 0.302 | 1.000 | 2700 | tags=25%, list=15%, signal=29% | |
| 166 | INOH_SIGNALING WITH WNT (XENOPUS) | 16 | -0.59 | -1.35 | 0.143 | 0.304 | 1.000 | 1922 | tags=25%, list=10%, signal=28% | |
| 167 | REACTOME_INNATE_IMMUNITY_SIGNALING | 40 | -0.50 | -1.34 | 0.128 | 0.315 | 1.000 | 1773 | tags=23%, list=10%, signal=25% | |
| 168 | NCI_SIGNALING EVENTS REGULATED BY RET TYROSINE KINASE | 67 | -0.46 | -1.34 | 0.105 | 0.317 | 1.000 | 2256 | tags=36%, list=12%, signal=41% | |
| 169 | BIOCARTA_GAMMA-AMINOBUTYRIC ACID RECEPTOR LIFE CYCLE PATHWAY | 14 | -0.59 | -1.33 | 0.141 | 0.319 | 1.000 | 3049 | tags=36%, list=16%, signal=43% | |
| 170 | CELLMAP_NOTCH | 45 | -0.48 | -1.33 | 0.114 | 0.323 | 1.000 | 2222 | tags=33%, list=12%, signal=38% | |
| 171 | INOH_CYTOSOLIC CALCIUM ION CONCENTRATION ELEVATION (THROUGH IP3 RECEPTOR) | 14 | -0.60 | -1.33 | 0.153 | 0.324 | 1.000 | 4193 | tags=50%, list=23%, signal=64% | |
| 172 | NCI_PROTEOGYLCAN SYNDECAN-MEDIATED SIGNALING EVENTS | 229 | -0.40 | -1.32 | 0.072 | 0.328 | 1.000 | 3400 | tags=32%, list=18%, signal=39% | |
| 173 | NETPATH_FLK2_FLT3 | 16 | -0.58 | -1.32 | 0.151 | 0.329 | 1.000 | 1354 | tags=38%, list=7%, signal=40% | |
| 174 | BIOCARTA_TRKA RECEPTOR SIGNALING PATHWAY | 11 | -0.63 | -1.32 | 0.173 | 0.328 | 1.000 | 1129 | tags=27%, list=6%, signal=29% | |
| 175 | BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS | 19 | -0.56 | -1.32 | 0.152 | 0.327 | 1.000 | 3664 | tags=37%, list=20%, signal=46% | |
| 176 | BIOCARTA_REPRESSION OF PAIN SENSATION BY THE TRANSCRIPTIONAL REGULATOR DREAM | 14 | -0.60 | -1.32 | 0.154 | 0.326 | 1.000 | 2074 | tags=57%, list=11%, signal=64% | |
| 177 | INOH_ERK CASCADE | 12 | -0.62 | -1.31 | 0.161 | 0.331 | 1.000 | 2385 | tags=33%, list=13%, signal=38% | |
| 178 | INOH_PLC BETA SIGNALING | 18 | -0.56 | -1.31 | 0.184 | 0.335 | 1.000 | 4193 | tags=44%, list=23%, signal=57% | |
| 179 | NETPATH_IL3 | 64 | -0.45 | -1.31 | 0.106 | 0.334 | 1.000 | 3240 | tags=42%, list=17%, signal=51% | |
| 180 | BIOCARTA_CERAMIDE SIGNALING PATHWAY | 48 | -0.48 | -1.31 | 0.133 | 0.334 | 1.000 | 2578 | tags=40%, list=14%, signal=46% | |
| 181 | REACTOME_SIGNALLING_TO_ERKS | 13 | -0.60 | -1.30 | 0.187 | 0.339 | 1.000 | 3149 | tags=46%, list=17%, signal=56% | |
| 182 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH JNK CASCADE)(CANONICAL) | 23 | -0.53 | -1.30 | 0.152 | 0.340 | 1.000 | 2762 | tags=48%, list=15%, signal=56% | |
| 183 | INOH_SIGNALING WITHOUT WNT (CANONICAL) | 27 | -0.52 | -1.29 | 0.137 | 0.345 | 1.000 | 3294 | tags=41%, list=18%, signal=49% | |
| 184 | NCI_SIGNALING EVENTS ACTIVATED BY HEPATOCYTE GROWTH FACTOR RECEPTOR (C-MET) | 142 | -0.41 | -1.29 | 0.118 | 0.349 | 1.000 | 3347 | tags=36%, list=18%, signal=43% | |
| 185 | BIOCARTA_MULTIPLE ANTIAPOPTOTIC PATHWAYS FROM IGF-1R SIGNALING LEAD TO BAD PHOSPHORYLATION | 13 | -0.58 | -1.29 | 0.171 | 0.354 | 1.000 | 3046 | tags=38%, list=16%, signal=46% | |
| 186 | NCI_SIGNALING EVENTS MEDIATED BY PTP1B | 46 | -0.47 | -1.29 | 0.137 | 0.352 | 1.000 | 3407 | tags=33%, list=18%, signal=40% | |
| 187 | NCI_ANDROGEN-MEDIATED SIGNALING | 101 | -0.42 | -1.28 | 0.118 | 0.354 | 1.000 | 2439 | tags=34%, list=13%, signal=39% | |
| 188 | BIOCARTA_IL-7 SIGNAL TRANSDUCTION | 14 | -0.59 | -1.28 | 0.183 | 0.356 | 1.000 | 4305 | tags=57%, list=23%, signal=74% | |
| 189 | INOH_SIGNALING WITHOUT WNT (MAMMAL) | 24 | -0.52 | -1.28 | 0.156 | 0.356 | 1.000 | 2726 | tags=33%, list=15%, signal=39% | |
| 190 | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE) | 32 | -0.50 | -1.28 | 0.154 | 0.357 | 1.000 | 2385 | tags=41%, list=13%, signal=47% | |
| 191 | INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY | 132 | -0.40 | -1.27 | 0.112 | 0.360 | 1.000 | 2762 | tags=31%, list=15%, signal=36% | |
| 192 | INOH_SIGNALING WITH WNT (MAMMAL) | 52 | -0.45 | -1.27 | 0.156 | 0.360 | 1.000 | 2149 | tags=19%, list=12%, signal=22% | |
| 193 | INOH_CD4 T CELL RECEPTOR SIGNALING (THROUGH VAV, RAC AND JNK CASCADE | 36 | -0.49 | -1.27 | 0.171 | 0.359 | 1.000 | 2187 | tags=33%, list=12%, signal=38% | |
| 194 | BIOCARTA_ROLE OF MEF2D IN T-CELL APOPTOSIS | 25 | -0.53 | -1.27 | 0.208 | 0.359 | 1.000 | 3742 | tags=44%, list=20%, signal=55% | |
| 195 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | 12 | -0.61 | -1.27 | 0.202 | 0.360 | 1.000 | 898 | tags=25%, list=5%, signal=26% | |
| 196 | INOH_IL-1_SIGNALING(THROUGH_JNK_CASCADE)(CANONICAL) | 24 | -0.51 | -1.27 | 0.181 | 0.360 | 1.000 | 2762 | tags=46%, list=15%, signal=54% | |
| 197 | INOH_GENE EXPROSSION OF SMAD6/7 BY R-SMAD:SMAD4 | 13 | -0.58 | -1.27 | 0.187 | 0.359 | 1.000 | 2588 | tags=38%, list=14%, signal=45% | |
| 198 | NCI_LPA4-MEDIATED SIGNALING EVENTS | 12 | -0.59 | -1.27 | 0.216 | 0.359 | 1.000 | 2179 | tags=33%, list=12%, signal=38% | |
| 199 | INOH_NEGATIVE FEEDBACK REGULATION PATHWAY OF TGF BETA SUPERFAMILY SIGNALING BY (BINDING OF SMAD6/7 AND TGF BETA RECEPTOR I) | 13 | -0.58 | -1.27 | 0.199 | 0.358 | 1.000 | 2588 | tags=38%, list=14%, signal=45% | |
| 200 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | 13 | -0.59 | -1.27 | 0.183 | 0.356 | 1.000 | 116 | tags=8%, list=1%, signal=8% | |
| 201 | INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY | 196 | -0.39 | -1.26 | 0.110 | 0.357 | 1.000 | 2237 | tags=24%, list=12%, signal=27% | |
| 202 | INOH_SIGNALING WITH WNT (CANONICAL) | 55 | -0.45 | -1.26 | 0.144 | 0.355 | 1.000 | 3816 | tags=29%, list=20%, signal=36% | |
| 203 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | 41 | -0.47 | -1.26 | 0.152 | 0.355 | 1.000 | 1708 | tags=20%, list=9%, signal=21% | |
| 204 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | 11 | -0.61 | -1.26 | 0.184 | 0.354 | 1.000 | 4975 | tags=64%, list=27%, signal=87% | |
| 205 | NCI_SYNDECAN-1-MEDIATED SIGNALING EVENTS | 150 | -0.39 | -1.26 | 0.109 | 0.357 | 1.000 | 3347 | tags=35%, list=18%, signal=43% | |
| 206 | BIOCARTA_TELOMERES TELOMERASE CELLULAR AGING AND IMMORTALITY | 15 | -0.55 | -1.25 | 0.216 | 0.360 | 1.000 | 510 | tags=20%, list=3%, signal=21% | |
| 207 | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE) | 26 | -0.50 | -1.25 | 0.182 | 0.359 | 1.000 | 2187 | tags=42%, list=12%, signal=48% | |
| 208 | BIOCARTA_MAP KINASE INACTIVATION OF SMRT COREPRESSOR | 17 | -0.55 | -1.25 | 0.207 | 0.358 | 1.000 | 4000 | tags=35%, list=21%, signal=45% | |
| 209 | BIOCARTA_IL 2 SIGNALING PATHWAY | 14 | -0.58 | -1.25 | 0.215 | 0.358 | 1.000 | 1323 | tags=21%, list=7%, signal=23% | |
| 210 | REACTOME_DEATH_RECEPTOR__SIGNALLING | 11 | -0.61 | -1.25 | 0.227 | 0.356 | 1.000 | 4975 | tags=64%, list=27%, signal=87% | |
| 211 | REACTOME_HEMOSTASIS | 147 | -0.39 | -1.25 | 0.123 | 0.356 | 1.000 | 1954 | tags=18%, list=10%, signal=20% | |
| 212 | INOH_BETA CATENIN DEGRADATION SIGNALING (CANONICAL) | 22 | -0.51 | -1.25 | 0.169 | 0.355 | 1.000 | 3294 | tags=41%, list=18%, signal=50% | |
| 213 | NCI_STABILIZATION AND EXPANSION OF THE E-CADHERIN ADHERENS JUNCTION | 14 | -0.57 | -1.25 | 0.189 | 0.355 | 1.000 | 3299 | tags=50%, list=18%, signal=61% | |
| 214 | NCI_SIGNALING EVENTS MEDIATED BY PRL | 21 | -0.52 | -1.25 | 0.191 | 0.355 | 1.000 | 1466 | tags=33%, list=8%, signal=36% | |
| 215 | REACTOME_GAMMA_CARBOXYLATION__TRANSPORT__AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | 10 | -0.60 | -1.25 | 0.237 | 0.357 | 1.000 | 1777 | tags=20%, list=10%, signal=22% | |
| 216 | REACTOME_NEURORANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE__POSTSYNAPTIC_CELL | 21 | -0.53 | -1.25 | 0.192 | 0.356 | 1.000 | 2385 | tags=33%, list=13%, signal=38% | |
| 217 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, JNK CASCADE) | 19 | -0.53 | -1.24 | 0.195 | 0.358 | 1.000 | 2762 | tags=47%, list=15%, signal=56% | |
| 218 | REACTOME_TOLL_LIKE_RECEPTOR_3__TLR3__CASCADE | 14 | -0.56 | -1.24 | 0.212 | 0.362 | 1.000 | 1773 | tags=43%, list=10%, signal=47% | |
| 219 | REACTOME_SYNAPTIC_TRANSMISSION | 42 | -0.46 | -1.24 | 0.183 | 0.365 | 1.000 | 1708 | tags=19%, list=9%, signal=21% | |
| 220 | BIOCARTA_CELL CYCLE: G2/M CHECKPOINT | 19 | -0.52 | -1.23 | 0.219 | 0.367 | 1.000 | 725 | tags=26%, list=4%, signal=27% | |
| 221 | REACTOME_PLATELET_ACTIVATION | 69 | -0.42 | -1.23 | 0.167 | 0.368 | 1.000 | 1789 | tags=16%, list=10%, signal=18% | |
| 222 | REACTOME_CD28_CO_STIMULATION | 12 | -0.56 | -1.23 | 0.223 | 0.368 | 1.000 | 490 | tags=17%, list=3%, signal=17% | |
| 223 | REACTOME_DOWNSTREAM_TCR_SIGNALING | 19 | -0.52 | -1.23 | 0.217 | 0.369 | 1.000 | 1235 | tags=32%, list=7%, signal=34% | |
| 224 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA Q, PLC BETA AND ERK CASCADE) | 185 | -0.37 | -1.23 | 0.129 | 0.368 | 1.000 | 4910 | tags=30%, list=26%, signal=41% | |
| 225 | BIOCARTA_MELANOCYTE DEVELOPMENT AND PIGMENTATION PATHWAY | 12 | -0.56 | -1.23 | 0.220 | 0.366 | 1.000 | 2385 | tags=33%, list=13%, signal=38% | |
| 226 | INOH_G ALPHA S GDP-GTP EXCHANGE SIGNALING | 105 | -0.40 | -1.23 | 0.145 | 0.366 | 1.000 | 2385 | tags=23%, list=13%, signal=26% | |
| 227 | INOH_BMP2 SIGNALING PATHWAY(THROUGH SMAD) | 10 | -0.60 | -1.22 | 0.260 | 0.368 | 1.000 | 1136 | tags=30%, list=6%, signal=32% | |
| 228 | NCI_EPHRINB-EPHB PATHWAY | 52 | -0.43 | -1.22 | 0.175 | 0.368 | 1.000 | 1676 | tags=25%, list=9%, signal=27% | |
| 229 | REACTOME_OPIOID_SIGNALLING | 22 | -0.51 | -1.22 | 0.198 | 0.368 | 1.000 | 2864 | tags=36%, list=15%, signal=43% | |
| 230 | REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE | 35 | -0.48 | -1.22 | 0.194 | 0.367 | 1.000 | 1708 | tags=34%, list=9%, signal=38% | |
| 231 | BIOCARTA_METS AFFECT ON MACROPHAGE DIFFERENTIATION | 17 | -0.53 | -1.22 | 0.211 | 0.370 | 1.000 | 2578 | tags=35%, list=14%, signal=41% | |
| 232 | BIOCARTA_CXCR4 SIGNALING PATHWAY | 11 | -0.58 | -1.22 | 0.238 | 0.369 | 1.000 | 3046 | tags=36%, list=16%, signal=43% | |
| 233 | HUMANCYC_PHOSPHOLIPASES | 22 | -0.50 | -1.21 | 0.199 | 0.372 | 1.000 | 1078 | tags=14%, list=6%, signal=14% | |
| 234 | BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF | 17 | -0.54 | -1.21 | 0.256 | 0.372 | 1.000 | 2562 | tags=35%, list=14%, signal=41% | |
| 235 | BIOCARTA_THROMBIN SIGNALING AND PROTEASE-ACTIVATED RECEPTORS | 19 | -0.52 | -1.21 | 0.204 | 0.371 | 1.000 | 3046 | tags=37%, list=16%, signal=44% | |
| 236 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (P38 CASCADE) | 24 | -0.49 | -1.21 | 0.200 | 0.371 | 1.000 | 2762 | tags=46%, list=15%, signal=54% | |
| 237 | BIOCARTA_THE INFORMATION PROCESSING PATHWAY AT THE IFN BETA ENHANCER | 26 | -0.50 | -1.21 | 0.208 | 0.374 | 1.000 | 3053 | tags=58%, list=16%, signal=69% | |
| 238 | BIOCARTA_ACTIVATION OF CSK BY CAMP-DEPENDENT PROTEIN KINASE INHIBITS SIGNALING THROUGH THE T CELL RECEPTOR | 36 | -0.46 | -1.20 | 0.204 | 0.379 | 1.000 | 3742 | tags=31%, list=20%, signal=38% | |
| 239 | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING | 15 | -0.53 | -1.20 | 0.255 | 0.387 | 1.000 | 3185 | tags=47%, list=17%, signal=56% | |
| 240 | NCI_IL2 SIGNALING EVENTS MEDIATED BY STAT5 | 29 | -0.47 | -1.20 | 0.232 | 0.389 | 1.000 | 4305 | tags=45%, list=23%, signal=58% | |
| 241 | REACTOME_SIGNALING_BY_GPCR | 141 | -0.37 | -1.19 | 0.172 | 0.389 | 1.000 | 3374 | tags=18%, list=18%, signal=21% | |
| 242 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA S ACS EPAC BRAF AND ERKCASCADE) | 197 | -0.36 | -1.19 | 0.157 | 0.390 | 1.000 | 3961 | tags=23%, list=21%, signal=29% | |
| 243 | NCI_EPHRIN B REVERSE SIGNALING | 27 | -0.48 | -1.19 | 0.212 | 0.392 | 1.000 | 3407 | tags=41%, list=18%, signal=50% | |
| 244 | INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP. PKA, CBL AND C3G) | 11 | -0.56 | -1.19 | 0.265 | 0.395 | 1.000 | 1924 | tags=36%, list=10%, signal=41% | |
| 245 | NCI_INSULIN PATHWAY | 113 | -0.38 | -1.19 | 0.188 | 0.395 | 1.000 | 3847 | tags=36%, list=21%, signal=45% | |
| 246 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS II | 31 | -0.46 | -1.18 | 0.223 | 0.395 | 1.000 | 1563 | tags=26%, list=8%, signal=28% | |
| 247 | REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING | 15 | -0.53 | -1.18 | 0.266 | 0.397 | 1.000 | 3185 | tags=47%, list=17%, signal=56% | |
| 248 | BIOCARTA_NF-KB SIGNALING PATHWAY | 20 | -0.50 | -1.18 | 0.257 | 0.397 | 1.000 | 2158 | tags=30%, list=12%, signal=34% | |
| 249 | NCI_ARF6 TRAFFICKING EVENTS | 113 | -0.38 | -1.18 | 0.180 | 0.396 | 1.000 | 3847 | tags=36%, list=21%, signal=45% | |
| 250 | REACTOME_IRS_MEDIATED_SIGNALLING | 20 | -0.50 | -1.18 | 0.250 | 0.396 | 1.000 | 1354 | tags=30%, list=7%, signal=32% | |
| 251 | NCI_ALPHA-SYNUCLEIN SIGNALING | 32 | -0.45 | -1.18 | 0.235 | 0.396 | 1.000 | 2237 | tags=28%, list=12%, signal=32% | |
| 252 | NCI_ARF6 SIGNALING EVENTS | 113 | -0.38 | -1.17 | 0.197 | 0.407 | 1.000 | 3847 | tags=36%, list=21%, signal=45% | |
| 253 | REACTOME_IRS_RELATED_EVENTS | 21 | -0.50 | -1.17 | 0.263 | 0.406 | 1.000 | 1354 | tags=29%, list=7%, signal=31% | |
| 254 | INOH_BETA CATENIN DEGRADATION SIGNALING (MAMMAL) | 19 | -0.51 | -1.17 | 0.241 | 0.406 | 1.000 | 3294 | tags=37%, list=18%, signal=45% | |
| 255 | BIOCARTA_TREFOIL FACTORS INITIATE MUCOSAL HEALING | 34 | -0.45 | -1.17 | 0.241 | 0.405 | 1.000 | 2385 | tags=35%, list=13%, signal=40% | |
| 256 | INOH_DROSOPHILA TOLL-LIKE RECEPTOR SIGNALING | 193 | -0.35 | -1.16 | 0.187 | 0.412 | 1.000 | 2265 | tags=23%, list=12%, signal=26% | |
| 257 | INOH_G ALPHA I GDP-GTP EXCHANGE SIGNALING | 36 | -0.45 | -1.16 | 0.242 | 0.412 | 1.000 | 2179 | tags=17%, list=12%, signal=19% | |
| 258 | REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE | 22 | -0.49 | -1.16 | 0.272 | 0.412 | 1.000 | 1354 | tags=27%, list=7%, signal=29% | |
| 259 | NETPATH_IFN-GAMMA | 67 | -0.40 | -1.16 | 0.208 | 0.412 | 1.000 | 1924 | tags=33%, list=10%, signal=36% | |
| 260 | INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH G ALPHA I, ADENYLATE CYCLASE AND CAMP) | 175 | -0.36 | -1.16 | 0.187 | 0.410 | 1.000 | 4910 | tags=29%, list=26%, signal=38% | |
| 261 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, P38 CASCADE) | 20 | -0.49 | -1.16 | 0.256 | 0.413 | 1.000 | 2762 | tags=45%, list=15%, signal=53% | |
| 262 | REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE | 15 | -0.52 | -1.16 | 0.287 | 0.413 | 1.000 | 612 | tags=13%, list=3%, signal=14% | |
| 263 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA I AND PERTUSSIS TOXIN) | 175 | -0.36 | -1.15 | 0.204 | 0.414 | 1.000 | 4910 | tags=29%, list=26%, signal=38% | |
| 264 | BIOCARTA_GATA3 PARTICIPATE IN ACTIVATING THE TH2 CYTOKINE GENES EXPRESSION | 16 | -0.51 | -1.15 | 0.292 | 0.418 | 1.000 | 2762 | tags=44%, list=15%, signal=51% | |
| 265 | REACTOME_SIGNALING_BY_INSULIN_RECEPTOR | 22 | -0.49 | -1.15 | 0.274 | 0.417 | 1.000 | 1354 | tags=27%, list=7%, signal=29% | |
| 266 | REACTOME_AXON_GUIDANCE | 56 | -0.41 | -1.15 | 0.225 | 0.421 | 1.000 | 3558 | tags=45%, list=19%, signal=55% | |
| 267 | BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION | 10 | -0.55 | -1.14 | 0.316 | 0.424 | 1.000 | 3742 | tags=40%, list=20%, signal=50% | |
| 268 | BIOCARTA_ERYTHROPOIETIN MEDIATED NEUROPROTECTION THROUGH NF-KB | 12 | -0.53 | -1.14 | 0.309 | 0.424 | 1.000 | 1884 | tags=58%, list=10%, signal=65% | |
| 269 | BIOCARTA_CORTICOSTEROIDS AND CARDIOPROTECTION | 25 | -0.47 | -1.14 | 0.287 | 0.424 | 1.000 | 3046 | tags=28%, list=16%, signal=33% | |
| 270 | REACTOME_MEMBRANE_TRAFFICKING | 26 | -0.46 | -1.14 | 0.270 | 0.423 | 1.000 | 4033 | tags=46%, list=22%, signal=59% | |
| 271 | INOH_HETEROMERIC GPCR SIGNALING PATHWAY (THROUGH_G ALPHA S_ACS_PKA_BRAF_AND_ERKCASCADE)(CANONICAL) | 189 | -0.35 | -1.14 | 0.203 | 0.423 | 1.000 | 3918 | tags=22%, list=21%, signal=27% | |
| 272 | NCI_PDGFR-ALPHA SIGNALING PATHWAY | 20 | -0.48 | -1.14 | 0.277 | 0.422 | 1.000 | 4173 | tags=45%, list=22%, signal=58% | |
| 273 | BIOCARTA_FL-ARRESTINS IN GPCR DESENSITIZATION | 26 | -0.45 | -1.13 | 0.264 | 0.428 | 1.000 | 2700 | tags=19%, list=15%, signal=22% | |
| 274 | NCI_EPHB FORWARD SIGNALING | 35 | -0.44 | -1.13 | 0.262 | 0.428 | 1.000 | 1568 | tags=26%, list=8%, signal=28% | |
| 275 | BIOCARTA_ROLE OF PI3K SUBUNIT P85 IN REGULATION OF ACTIN ORGANIZATION AND CELL MIGRATION | 16 | -0.49 | -1.13 | 0.320 | 0.428 | 1.000 | 3859 | tags=44%, list=21%, signal=55% | |
| 276 | INOH_TGF BETA SIGNALING PATHWAY(THROUGH TAK1) | 13 | -0.51 | -1.13 | 0.309 | 0.435 | 1.000 | 2649 | tags=38%, list=14%, signal=45% | |
| 277 | NCI_VEGFR1 SPECIFIC SIGNALS | 27 | -0.45 | -1.13 | 0.290 | 0.433 | 1.000 | 2050 | tags=22%, list=11%, signal=25% | |
| 278 | NETPATH_IL1 | 27 | -0.46 | -1.12 | 0.299 | 0.435 | 1.000 | 1846 | tags=30%, list=10%, signal=33% | |
| 279 | BIOCARTA_IL 4 SIGNALING PATHWAY | 11 | -0.53 | -1.12 | 0.331 | 0.436 | 1.000 | 1310 | tags=27%, list=7%, signal=29% | |
| 280 | CELLMAP_ANDROGENRECEPTOR | 70 | -0.39 | -1.12 | 0.246 | 0.435 | 1.000 | 1843 | tags=31%, list=10%, signal=35% | |
| 281 | INOH_IL-1 SIGNALING PATHWAY (THROUGH P38 CASCADE) | 24 | -0.45 | -1.12 | 0.301 | 0.438 | 1.000 | 2762 | tags=42%, list=15%, signal=49% | |
| 282 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_THE_ANTIVIRAL_CYTOKINE_IFN_ALPHA_BETA_CASCADE | 12 | -0.53 | -1.12 | 0.342 | 0.437 | 1.000 | 1773 | tags=42%, list=10%, signal=46% | |
| 283 | BIOCARTA_PLATELET AMYLOID PRECURSOR PROTEIN PATHWAY | 13 | -0.51 | -1.12 | 0.320 | 0.436 | 1.000 | 1804 | tags=15%, list=10%, signal=17% | |
| 284 | NCI_RETINOIC ACID RECEPTORS-MEDIATED SIGNALING | 37 | -0.43 | -1.12 | 0.283 | 0.436 | 1.000 | 1744 | tags=24%, list=9%, signal=27% | |
| 285 | REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS | 13 | -0.50 | -1.12 | 0.312 | 0.435 | 1.000 | 4079 | tags=62%, list=22%, signal=79% | |
| 286 | BIOCARTA_ACTIVATION OF PKC THROUGH G-PROTEIN COUPLED RECEPTORS | 10 | -0.54 | -1.11 | 0.341 | 0.439 | 1.000 | 4405 | tags=50%, list=24%, signal=65% | |
| 287 | NCI_NECTIN ADHESION PATHWAY | 94 | -0.36 | -1.11 | 0.248 | 0.438 | 1.000 | 3550 | tags=39%, list=19%, signal=48% | |
| 288 | INOH_PKA ACTIVATION SIGNALING | 46 | -0.41 | -1.11 | 0.296 | 0.438 | 1.000 | 2180 | tags=24%, list=12%, signal=27% | |
| 289 | NCI_SIGNALING EVENTS MEDIATED BY VEGFR1 AND VEGFR2 | 62 | -0.39 | -1.11 | 0.267 | 0.440 | 1.000 | 2085 | tags=24%, list=11%, signal=27% | |
| 290 | NETPATH_GDNF | 29 | -0.44 | -1.11 | 0.290 | 0.439 | 1.000 | 1711 | tags=21%, list=9%, signal=23% | |
| 291 | BIOCARTA_MECHANISM OF GENE REGULATION BY PEROXISOME PROLIFERATORS VIA PPARA | 33 | -0.43 | -1.10 | 0.299 | 0.448 | 1.000 | 2080 | tags=30%, list=11%, signal=34% | |
| 292 | BIOCARTA_HYPOXIA AND P53 IN THE CARDIOVASCULAR SYSTEM | 16 | -0.48 | -1.10 | 0.325 | 0.449 | 1.000 | 984 | tags=31%, list=5%, signal=33% | |
| 293 | BIOCARTA_TNF/STRESS RELATED SIGNALING | 22 | -0.46 | -1.10 | 0.313 | 0.447 | 1.000 | 4975 | tags=55%, list=27%, signal=74% | |
| 294 | BIOCARTA_ATM SIGNALING PATHWAY | 16 | -0.47 | -1.10 | 0.339 | 0.448 | 1.000 | 1773 | tags=44%, list=10%, signal=48% | |
| 295 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | 12 | -0.50 | -1.10 | 0.348 | 0.448 | 1.000 | 3185 | tags=50%, list=17%, signal=60% | |
| 296 | NCI_FOXA1 TRANSCRIPTION FACTOR NETWORK | 33 | -0.42 | -1.10 | 0.307 | 0.449 | 1.000 | 4235 | tags=42%, list=23%, signal=55% | |
| 297 | BIOCARTA_IL 6 SIGNALING PATHWAY | 13 | -0.49 | -1.10 | 0.368 | 0.448 | 1.000 | 1129 | tags=23%, list=6%, signal=25% | |
| 298 | INOH_NEGATIVE REGULATION OF (TRANSCRIPTION BY R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY | 18 | -0.47 | -1.09 | 0.345 | 0.453 | 1.000 | 2149 | tags=39%, list=12%, signal=44% | |
| 299 | REACTOME_SIGNALING_BY_PDGF | 21 | -0.45 | -1.09 | 0.340 | 0.453 | 1.000 | 3664 | tags=38%, list=20%, signal=47% | |
| 300 | BIOCARTA_IL-2 RECEPTOR BETA CHAIN IN T CELL ACTIVATION | 48 | -0.39 | -1.08 | 0.313 | 0.465 | 1.000 | 2504 | tags=31%, list=13%, signal=36% | |
| 301 | BIOCARTA_HOW PROGESTERONE INITIATES THE OOCYTE MATURATION | 19 | -0.47 | -1.08 | 0.340 | 0.464 | 1.000 | 2074 | tags=26%, list=11%, signal=30% | |
| 302 | CELLMAP_WNT | 65 | -0.37 | -1.08 | 0.318 | 0.463 | 1.000 | 2702 | tags=22%, list=15%, signal=25% | |
| 303 | INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP AND EPAC) | 22 | -0.45 | -1.08 | 0.323 | 0.462 | 1.000 | 2321 | tags=36%, list=12%, signal=41% | |
| 304 | INOH_HETEROTRIMERIC GTP-BINDING PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY (THROUGH_G_ALPHA_S,_CHOLERA_TOXIN,_ADENYLATE_CYCLASE_AND_CAMP) | 179 | -0.33 | -1.08 | 0.286 | 0.462 | 1.000 | 4910 | tags=28%, list=26%, signal=38% | |
| 305 | BIOCARTA_SEGMENTATION CLOCK | 22 | -0.45 | -1.07 | 0.369 | 0.472 | 1.000 | 3538 | tags=32%, list=19%, signal=39% | |
| 306 | NCI_COREGULATION OF ANDROGEN RECEPTOR ACTIVITY | 43 | -0.39 | -1.07 | 0.351 | 0.478 | 1.000 | 2677 | tags=33%, list=14%, signal=38% | |
| 307 | BIOCARTA_REGULATION OF EIF-4E AND P70S6 KINASE | 22 | -0.43 | -1.06 | 0.349 | 0.483 | 1.000 | 2029 | tags=36%, list=11%, signal=41% | |
| 308 | NCI_CLASS I PI3K SIGNALING EVENTS MEDIATED BY AKT | 86 | -0.35 | -1.06 | 0.317 | 0.487 | 1.000 | 3149 | tags=42%, list=17%, signal=50% | |
| 309 | REACTOME_DOWN_STREAM_SIGNAL_TRANSDUCTION | 17 | -0.45 | -1.06 | 0.381 | 0.486 | 1.000 | 3664 | tags=41%, list=20%, signal=51% | |
| 310 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | 16 | -0.47 | -1.06 | 0.390 | 0.486 | 1.000 | 3742 | tags=25%, list=20%, signal=31% | |
| 311 | INOH_JNK CASCADE | 16 | -0.48 | -1.06 | 0.401 | 0.491 | 1.000 | 2762 | tags=38%, list=15%, signal=44% | |
| 312 | INOH_B-RAF ACTIVATION SIGNALING | 26 | -0.43 | -1.05 | 0.388 | 0.504 | 1.000 | 2321 | tags=35%, list=12%, signal=39% | |
| 313 | NCI_IGF1 PATHWAY | 124 | -0.33 | -1.05 | 0.343 | 0.504 | 1.000 | 3347 | tags=32%, list=18%, signal=39% | |
| 314 | INOH_MAMMALIAN WNT SIGNALING PATHWAY | 70 | -0.36 | -1.04 | 0.332 | 0.506 | 1.000 | 2149 | tags=16%, list=12%, signal=18% | |
| 315 | BIOCARTA_RAS SIGNALING PATHWAY | 19 | -0.44 | -1.04 | 0.408 | 0.510 | 1.000 | 3046 | tags=42%, list=16%, signal=50% | |
| 316 | NETPATH_NGF | 45 | -0.39 | -1.04 | 0.379 | 0.511 | 1.000 | 2010 | tags=29%, list=11%, signal=32% | |
| 317 | NCI_VEGFR3 SIGNALING IN LYMPHATIC ENDOTHELIUM | 22 | -0.42 | -1.04 | 0.388 | 0.511 | 1.000 | 2173 | tags=27%, list=12%, signal=31% | |
| 318 | NCI_FOXO FAMILY SIGNALING | 43 | -0.39 | -1.03 | 0.395 | 0.519 | 1.000 | 1930 | tags=23%, list=10%, signal=26% | |
| 319 | BIOCARTA_CTCF: FIRST MULTIVALENT NUCLEAR FACTOR | 23 | -0.42 | -1.03 | 0.394 | 0.520 | 1.000 | 1753 | tags=57%, list=9%, signal=62% | |
| 320 | REACTOME_COMMON_PATHWAY | 11 | -0.48 | -1.02 | 0.424 | 0.533 | 1.000 | 3620 | tags=27%, list=19%, signal=34% | |
| 321 | INOH_P38 CASCADE | 12 | -0.49 | -1.02 | 0.455 | 0.532 | 1.000 | 2762 | tags=50%, list=15%, signal=59% | |
| 322 | INOH_DROSOPHILA WINGLESS/WNT SIGNALING PATHWAY | 13 | -0.45 | -1.02 | 0.411 | 0.532 | 1.000 | 2149 | tags=23%, list=12%, signal=26% | |
| 323 | NCI_EPHRINA-EPHA PATHWAY | 40 | -0.39 | -1.02 | 0.406 | 0.531 | 1.000 | 3407 | tags=35%, list=18%, signal=43% | |
| 324 | BIOCARTA_ASPIRIN BLOCKS SIGNALING PATHWAY INVOLVED IN PLATELET ACTIVATION | 16 | -0.46 | -1.02 | 0.441 | 0.531 | 1.000 | 2385 | tags=25%, list=13%, signal=29% | |
| 325 | NCI_CERAMIDE SIGNALING PATHWAY | 41 | -0.38 | -1.01 | 0.402 | 0.544 | 1.000 | 2532 | tags=39%, list=14%, signal=45% | |
| 326 | BIOCARTA_PHOSPHOLIPASE C-EPSILON PATHWAY | 11 | -0.48 | -1.01 | 0.452 | 0.543 | 1.000 | 3693 | tags=55%, list=20%, signal=68% | |
| 327 | REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS | 18 | -0.43 | -1.01 | 0.435 | 0.545 | 1.000 | 2385 | tags=28%, list=13%, signal=32% | |
| 328 | NCI_HIF-1-ALPHA TRANSCRIPTION FACTOR NETWORK | 57 | -0.36 | -1.00 | 0.432 | 0.552 | 1.000 | 2176 | tags=30%, list=12%, signal=34% | |
| 329 | INOH_NEGATIVE REGULATION OF (NUCLEAR IMPORT OF R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY | 10 | -0.49 | -1.00 | 0.475 | 0.550 | 1.000 | 1744 | tags=40%, list=9%, signal=44% | |
| 330 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | 18 | -0.43 | -1.00 | 0.444 | 0.554 | 1.000 | 2385 | tags=28%, list=13%, signal=32% | |
| 331 | REACTOME_FORMATION_OF_PLATELET_PLUG | 81 | -0.34 | -1.00 | 0.422 | 0.555 | 1.000 | 1789 | tags=15%, list=10%, signal=16% | |
| 332 | INOH_CANONICAL WNT SIGNALING PATHWAY | 73 | -0.34 | -1.00 | 0.436 | 0.556 | 1.000 | 3294 | tags=21%, list=18%, signal=25% | |
| 333 | REACTOME_PLC_BETA_MEDIATED_EVENTS | 10 | -0.49 | -1.00 | 0.458 | 0.555 | 1.000 | 1708 | tags=30%, list=9%, signal=33% | |
| 334 | NCI_SIGNALING EVENTS MEDIATED BY THE HEDGEHOG FAMILY | 59 | -0.35 | -0.99 | 0.414 | 0.559 | 1.000 | 3397 | tags=31%, list=18%, signal=37% | |
| 335 | BIOCARTA_ADP-RIBOSYLATION FACTOR | 18 | -0.43 | -0.99 | 0.446 | 0.557 | 1.000 | 3847 | tags=50%, list=21%, signal=63% | |
| 336 | BIOCARTA_PHOSPHOLIPIDS AS SIGNALLING INTERMEDIARIES | 29 | -0.39 | -0.99 | 0.436 | 0.557 | 1.000 | 3046 | tags=38%, list=16%, signal=45% | |
| 337 | CELLMAP_TGFBR | 107 | -0.33 | -0.99 | 0.436 | 0.557 | 1.000 | 2080 | tags=26%, list=11%, signal=29% | |
| 338 | BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY | 27 | -0.40 | -0.98 | 0.450 | 0.567 | 1.000 | 3580 | tags=41%, list=19%, signal=50% | |
| 339 | NCI_P38 SIGNALING MEDIATED BY MAPKAP KINASES | 21 | -0.41 | -0.97 | 0.449 | 0.580 | 1.000 | 3149 | tags=38%, list=17%, signal=46% | |
| 340 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS | 10 | -0.47 | -0.97 | 0.507 | 0.586 | 1.000 | 4407 | tags=40%, list=24%, signal=52% | |
| 341 | BIOCARTA_FAS SIGNALING PATHWAY (CD95) | 19 | -0.41 | -0.96 | 0.494 | 0.594 | 1.000 | 4170 | tags=53%, list=22%, signal=68% | |
| 342 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | 56 | -0.34 | -0.96 | 0.443 | 0.594 | 1.000 | 1954 | tags=13%, list=10%, signal=14% | |
| 343 | NCI_REELIN SIGNALING PATHWAY | 27 | -0.39 | -0.96 | 0.499 | 0.593 | 1.000 | 3811 | tags=44%, list=20%, signal=56% | |
| 344 | REACTOME_CLASS_B_2__SECRETIN_FAMILY_RECEPTORS_ | 23 | -0.40 | -0.96 | 0.490 | 0.593 | 1.000 | 1643 | tags=9%, list=9%, signal=10% | |
| 345 | REACTOME_G_PROTEIN_MEDIATED_EVENTS | 11 | -0.46 | -0.96 | 0.513 | 0.597 | 1.000 | 1708 | tags=27%, list=9%, signal=30% | |
| 346 | BIOCARTA_NERVE GROWTH FACTOR PATHWAY (NGF) | 15 | -0.42 | -0.95 | 0.526 | 0.611 | 1.000 | 3046 | tags=33%, list=16%, signal=40% | |
| 347 | BIOCARTA_INACTIVATION OF GSK3 BY AKT CAUSES ACCUMULATION OF B-CATENIN IN ALVEOLAR MACROPHAGES | 38 | -0.36 | -0.95 | 0.487 | 0.611 | 1.000 | 2158 | tags=24%, list=12%, signal=27% | |
| 348 | REACTOME_PI3K_AKT_SIGNALLING | 12 | -0.45 | -0.95 | 0.534 | 0.613 | 1.000 | 1708 | tags=50%, list=9%, signal=55% | |
| 349 | REACTOME_FORMATION_OF_FIBRIN_CLOT__CLOTTING_CASCADE_ | 28 | -0.37 | -0.94 | 0.512 | 0.629 | 1.000 | 1037 | tags=11%, list=6%, signal=11% | |
| 350 | BIOCARTA_NITRIC OXIDE SIGNALING PATHWAY | 16 | -0.42 | -0.93 | 0.534 | 0.639 | 1.000 | 2263 | tags=31%, list=12%, signal=36% | |
| 351 | BIOCARTA_CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) AND BETA 2 ADRENERGIC RECEPTOR (B2AR) PATHWAY | 17 | -0.40 | -0.93 | 0.520 | 0.638 | 1.000 | 2700 | tags=29%, list=15%, signal=34% | |
| 352 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | 12 | -0.44 | -0.93 | 0.537 | 0.637 | 1.000 | 1488 | tags=25%, list=8%, signal=27% | |
| 353 | REACTOME_INTRINSIC_PATHWAY | 16 | -0.42 | -0.93 | 0.533 | 0.636 | 1.000 | 1037 | tags=13%, list=6%, signal=13% | |
| 354 | REACTOME_PI3K_CASCADE | 12 | -0.43 | -0.92 | 0.527 | 0.643 | 1.000 | 786 | tags=25%, list=4%, signal=26% | |
| 355 | REACTOME_CREB_PHOPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | 15 | -0.41 | -0.92 | 0.544 | 0.651 | 1.000 | 2385 | tags=27%, list=13%, signal=31% | |
| 356 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | 25 | -0.37 | -0.91 | 0.550 | 0.656 | 1.000 | 3133 | tags=24%, list=17%, signal=29% | |
| 357 | BIOCARTA_ACTIVATION OF CAMP-DEPENDENT PROTEIN KINASE PKA | 25 | -0.37 | -0.91 | 0.561 | 0.655 | 1.000 | 2700 | tags=20%, list=15%, signal=23% | |
| 358 | NCI_ARF1 PATHWAY | 13 | -0.41 | -0.90 | 0.577 | 0.678 | 1.000 | 4211 | tags=54%, list=23%, signal=70% | |
| 359 | BIOCARTA_SUMOYLATION BY RANBP2 REGULATES TRANSCRIPTIONAL REPRESSION | 12 | -0.41 | -0.90 | 0.597 | 0.682 | 1.000 | 1418 | tags=33%, list=8%, signal=36% | |
| 360 | BIOCARTA_REGULATION OF BAD PHOSPHORYLATION | 20 | -0.37 | -0.89 | 0.579 | 0.685 | 1.000 | 2074 | tags=25%, list=11%, signal=28% | |
| 361 | BIOCARTA_ATTENUATION OF GPCR SIGNALING | 11 | -0.41 | -0.89 | 0.581 | 0.688 | 1.000 | 2074 | tags=27%, list=11%, signal=31% | |
| 362 | INOH_WNT SECRETORY PATHWAY (CANONICAL) | 47 | -0.32 | -0.89 | 0.573 | 0.690 | 1.000 | 1890 | tags=13%, list=10%, signal=14% | |
| 363 | NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS | 44 | -0.32 | -0.89 | 0.616 | 0.697 | 1.000 | 3625 | tags=32%, list=19%, signal=39% | |
| 364 | BIOCARTA_Y BRANCHING OF ACTIN FILAMENTS | 16 | -0.40 | -0.88 | 0.596 | 0.695 | 1.000 | 1523 | tags=19%, list=8%, signal=20% | |
| 365 | HUMANCYC_TRIACYLGLYCEROL BIOSYNTHESIS | 11 | -0.41 | -0.87 | 0.633 | 0.728 | 1.000 | 4276 | tags=36%, list=23%, signal=47% | |
| 366 | INOH_WNT SECRETORY PATHWAY (MAMMAL) | 48 | -0.31 | -0.86 | 0.628 | 0.733 | 1.000 | 1890 | tags=13%, list=10%, signal=14% | |
| 367 | NCI_FOXA TRANSCRIPTION FACTOR NETWORKS | 65 | -0.30 | -0.86 | 0.639 | 0.732 | 1.000 | 3625 | tags=29%, list=19%, signal=36% | |
| 368 | BIOCARTA_DOUBLE STRANDED RNA INDUCED GENE EXPRESSION | 12 | -0.40 | -0.86 | 0.652 | 0.734 | 1.000 | 2158 | tags=33%, list=12%, signal=38% | |
| 369 | BIOCARTA_IL-10 ANTI-INFLAMMATORY SIGNALING PATHWAY | 13 | -0.41 | -0.86 | 0.621 | 0.732 | 1.000 | 1766 | tags=31%, list=9%, signal=34% | |
| 370 | REACTOME_METABOLISM_OF_BILE_ACIDS_AND_BILE_SALTS | 14 | -0.39 | -0.85 | 0.662 | 0.747 | 1.000 | 4407 | tags=29%, list=24%, signal=37% | |
| 371 | BIOCARTA_IGF-1 SIGNALING PATHWAY | 19 | -0.36 | -0.85 | 0.665 | 0.754 | 1.000 | 3664 | tags=32%, list=20%, signal=39% | |
| 372 | NCI_EPHA2 FORWARD SIGNALING | 17 | -0.37 | -0.84 | 0.644 | 0.753 | 1.000 | 1464 | tags=24%, list=8%, signal=26% | |
| 373 | BIOCARTA_INTEGRIN SIGNALING PATHWAY | 30 | -0.32 | -0.84 | 0.655 | 0.763 | 1.000 | 3240 | tags=40%, list=17%, signal=48% | |
| 374 | BIOCARTA_REGULATION OF CK1/CDK5 BY TYPE 1 GLUTAMATE RECEPTORS | 22 | -0.34 | -0.83 | 0.706 | 0.776 | 1.000 | 3693 | tags=36%, list=20%, signal=45% | |
| 375 | INOH_XENOPUS AXIS FORMATION WNT SIGNALING PATHWAY | 42 | -0.30 | -0.82 | 0.723 | 0.788 | 1.000 | 1922 | tags=12%, list=10%, signal=13% | |
| 376 | NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING | 40 | -0.30 | -0.82 | 0.714 | 0.789 | 1.000 | 3351 | tags=40%, list=18%, signal=49% | |
| 377 | NCI_RXR AND RAR HETERODIMERIZATION WITH OTHER NUCLEAR RECEPTOR | 19 | -0.34 | -0.82 | 0.702 | 0.791 | 1.000 | 4881 | tags=32%, list=26%, signal=43% | |
| 378 | BIOCARTA_CHREBP REGULATION BY CARBOHYDRATES AND CAMP | 34 | -0.31 | -0.81 | 0.716 | 0.796 | 1.000 | 3035 | tags=21%, list=16%, signal=25% | |
| 379 | NCI_ANGIOPOIETIN RECEPTOR TIE2-MEDIATED SIGNALING | 44 | -0.31 | -0.81 | 0.716 | 0.795 | 1.000 | 2104 | tags=23%, list=11%, signal=26% | |
| 380 | BIOCARTA_ION CHANNELS AND THEIR FUNCTIONAL ROLE IN VASCULAR ENDOTHELIUM | 41 | -0.30 | -0.81 | 0.737 | 0.802 | 1.000 | 3693 | tags=20%, list=20%, signal=24% | |
| 381 | NCI_SYNDECAN-4-MEDIATED SIGNALING EVENTS | 47 | -0.30 | -0.81 | 0.725 | 0.804 | 1.000 | 3400 | tags=28%, list=18%, signal=34% | |
| 382 | REACTOME_EGFR_DOWNREGULATION | 10 | -0.39 | -0.81 | 0.715 | 0.802 | 1.000 | 3069 | tags=30%, list=16%, signal=36% | |
| 383 | BIOCARTA_FIBRINOLYSIS PATHWAY | 12 | -0.38 | -0.80 | 0.707 | 0.802 | 1.000 | 3620 | tags=33%, list=19%, signal=41% | |
| 384 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | 12 | -0.37 | -0.80 | 0.740 | 0.812 | 1.000 | 1779 | tags=17%, list=10%, signal=18% | |
| 385 | REACTOME_TIE2_SIGNALING | 12 | -0.37 | -0.79 | 0.734 | 0.814 | 1.000 | 229 | tags=8%, list=1%, signal=8% | |
| 386 | NCI_SUMOYLATION BY RANBP2 REGULATES TRANSCRIPTIONAL REPRESSION | 10 | -0.38 | -0.79 | 0.740 | 0.814 | 1.000 | 718 | tags=20%, list=4%, signal=21% | |
| 387 | BIOCARTA_HOW DOES SALMONELLA HIJACK A CELL | 11 | -0.37 | -0.79 | 0.712 | 0.822 | 1.000 | 3744 | tags=36%, list=20%, signal=45% | |
| 388 | REACTOME_STEROID_HORMONES | 13 | -0.36 | -0.78 | 0.756 | 0.829 | 1.000 | 6102 | tags=46%, list=33%, signal=69% | |
| 389 | BIOCARTA_PROTEIN KINASE A AT THE CENTROSOME | 10 | -0.38 | -0.77 | 0.756 | 0.842 | 1.000 | 4004 | tags=60%, list=22%, signal=76% | |
| 390 | REACTOME_CELL_JUNCTION_ORGANIZATION | 23 | -0.32 | -0.77 | 0.759 | 0.848 | 1.000 | 2348 | tags=22%, list=13%, signal=25% | |
| 391 | NCI_GLYPICAN 3 NETWORK | 57 | -0.27 | -0.77 | 0.851 | 0.847 | 1.000 | 1890 | tags=16%, list=10%, signal=18% | |
| 392 | REACTOME_CLASS_A_1__RHODOPSIN_LIKE_RECEPTORS_ | 93 | -0.25 | -0.77 | 0.863 | 0.845 | 1.000 | 3374 | tags=13%, list=18%, signal=16% | |
| 393 | BIOCARTA_ACTIONS OF NITRIC OXIDE IN THE HEART | 39 | -0.28 | -0.75 | 0.793 | 0.874 | 1.000 | 3046 | tags=18%, list=16%, signal=21% | |
| 394 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | 12 | -0.35 | -0.74 | 0.794 | 0.884 | 1.000 | 4120 | tags=33%, list=22%, signal=43% | |
| 395 | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | 22 | -0.31 | -0.74 | 0.837 | 0.883 | 1.000 | 2138 | tags=18%, list=11%, signal=21% | |
| 396 | BIOCARTA_TNFR1 SIGNALING PATHWAY | 16 | -0.31 | -0.70 | 0.833 | 0.921 | 1.000 | 4975 | tags=44%, list=27%, signal=60% | |
| 397 | BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2 | 22 | -0.29 | -0.70 | 0.882 | 0.926 | 1.000 | 3342 | tags=23%, list=18%, signal=28% | |
| 398 | BIOCARTA_THE IGF-1 RECEPTOR AND LONGEVITY | 16 | -0.30 | -0.69 | 0.867 | 0.936 | 1.000 | 1129 | tags=13%, list=6%, signal=13% | |
| 399 | NCI_NONCANONICAL WNT SIGNALING PATHWAY | 18 | -0.30 | -0.68 | 0.867 | 0.935 | 1.000 | 7421 | tags=72%, list=40%, signal=120% | |
| 400 | BIOCARTA_CASPASE CASCADE IN APOPTOSIS | 21 | -0.29 | -0.68 | 0.908 | 0.938 | 1.000 | 2830 | tags=29%, list=15%, signal=34% | |
| 401 | CELLMAP_HEDGEHOG | 14 | -0.30 | -0.68 | 0.880 | 0.936 | 1.000 | 3397 | tags=29%, list=18%, signal=35% | |
| 402 | BIOCARTA_INTRINSIC PROTHROMBIN ACTIVATION PATHWAY | 22 | -0.28 | -0.68 | 0.885 | 0.934 | 1.000 | 400 | tags=5%, list=2%, signal=5% | |
| 403 | NCI_INSULIN-MEDIATED GLUCOSE TRANSPORT | 24 | -0.28 | -0.67 | 0.894 | 0.936 | 1.000 | 3209 | tags=25%, list=17%, signal=30% | |
| 404 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | 16 | -0.30 | -0.67 | 0.886 | 0.935 | 1.000 | 4247 | tags=31%, list=23%, signal=40% | |
| 405 | BIOCARTA_ER ASSOCIATED DEGRADATION (ERAD) PATHWAY | 15 | -0.30 | -0.67 | 0.876 | 0.933 | 1.000 | 2968 | tags=27%, list=16%, signal=32% | |
| 406 | INOH_GROWTH HORMONE SIGNALING PATHWAY(JAK2 STAT5) | 10 | -0.32 | -0.66 | 0.887 | 0.946 | 1.000 | 1039 | tags=10%, list=6%, signal=11% | |
| 407 | REACTOME_PLATELET_DEGRANULATION_ | 42 | -0.24 | -0.64 | 0.958 | 0.955 | 1.000 | 4888 | tags=29%, list=26%, signal=39% | |
| 408 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA__ | 44 | -0.24 | -0.64 | 0.961 | 0.956 | 1.000 | 4888 | tags=27%, list=26%, signal=37% | |
| 409 | BIOCARTA_B CELL SURVIVAL PATHWAY | 12 | -0.30 | -0.63 | 0.918 | 0.956 | 1.000 | 3683 | tags=33%, list=20%, signal=42% | |
| 410 | BIOCARTA_THE CO-STIMULATORY SIGNAL DURING T-CELL ACTIVATION | 17 | -0.27 | -0.62 | 0.925 | 0.962 | 1.000 | 3407 | tags=18%, list=18%, signal=22% | |
| 411 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | 18 | -0.26 | -0.60 | 0.934 | 0.969 | 1.000 | 2940 | tags=22%, list=16%, signal=26% | |
| 412 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | 12 | -0.29 | -0.60 | 0.920 | 0.968 | 1.000 | 955 | tags=8%, list=5%, signal=9% | |
| 413 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | 53 | -0.21 | -0.58 | 0.993 | 0.978 | 1.000 | 1349 | tags=4%, list=7%, signal=4% | |
| 414 | REACTOME_HORMONE_BIOSYNTHESIS | 31 | -0.22 | -0.57 | 0.976 | 0.978 | 1.000 | 3322 | tags=16%, list=18%, signal=20% | |
| 415 | REACTOME_MUSCLE_CONTRACTION | 25 | -0.22 | -0.56 | 0.975 | 0.979 | 1.000 | 1779 | tags=12%, list=10%, signal=13% | |
| 416 | BIOCARTA_G-PROTEIN SIGNALING THROUGH TUBBY PROTEINS | 10 | -0.28 | -0.56 | 0.947 | 0.979 | 1.000 | 4405 | tags=30%, list=24%, signal=39% | |
| 417 | NCI_PAXILLIN-DEPENDENT EVENTS MEDIATED BY A4B1 | 17 | -0.24 | -0.55 | 0.973 | 0.979 | 1.000 | 5736 | tags=53%, list=31%, signal=76% | |
| 418 | REACTOME_EXOCYTOSIS_OF_ALPHA_GRANULE_ | 40 | -0.19 | -0.51 | 0.996 | 0.986 | 1.000 | 4888 | tags=28%, list=26%, signal=37% |