Details for gene set NUCLEAR

Table: GSEA Results Summary

Dataset	set03_wtNotch_versus_truncNotch
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	NUCLEAR_PART
Enrichment Score (ES)	0.37448063
Normalized Enrichment Score (NES)	2.0827394
Nominal p-value	0.0
FDR q-value	0.008037774
FWER p-Value	0.068

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SMC2	11	5.050	0.0073	Yes
2	EPC1	45	4.100	0.0119	Yes
3	TAF5	50	4.062	0.0180	Yes
4	BRCC3	109	3.671	0.0206	Yes
5	POLH	123	3.557	0.0254	Yes
6	KIN	134	3.536	0.0304	Yes
7	GNL3	150	3.491	0.0350	Yes
8	EED	177	3.421	0.0389	Yes
9	API5	189	3.387	0.0436	Yes
10	MPHOSPH1	246	3.248	0.0456	Yes
11	GTF3C4	253	3.239	0.0503	Yes
12	MDM2	259	3.228	0.0551	Yes
13	SMC1A	277	3.191	0.0592	Yes
14	CCNH	296	3.158	0.0631	Yes
15	SMAD4	362	3.068	0.0643	Yes
16	TERF2IP	363	3.068	0.0691	Yes
17	NARG1	373	3.040	0.0734	Yes
18	LBR	375	3.037	0.0781	Yes
19	TOP2B	406	2.984	0.0811	Yes
20	SNRPN	421	2.969	0.0849	Yes
21	RAD50	422	2.966	0.0896	Yes
22	TAF13	434	2.948	0.0936	Yes
23	KPNB1	493	2.884	0.0949	Yes
24	SMARCA5	496	2.882	0.0993	Yes
25	NUP107	499	2.875	0.1037	Yes
26	TOP1	502	2.872	0.1080	Yes
27	ZNF638	541	2.833	0.1104	Yes
28	RSF1	542	2.833	0.1148	Yes
29	CHEK2	545	2.831	0.1191	Yes
30	DHX15	558	2.822	0.1229	Yes
31	LYAR	597	2.784	0.1251	Yes
32	CDK8	622	2.758	0.1281	Yes
33	NFYB	631	2.753	0.1320	Yes
34	SMAD2	644	2.742	0.1356	Yes
35	RTN4	679	2.711	0.1380	Yes
36	SFRS2IP	680	2.710	0.1422	Yes
37	HDAC2	682	2.708	0.1464	Yes
38	TPR	702	2.694	0.1496	Yes
39	KPNA1	728	2.676	0.1524	Yes
40	BUB1B	774	2.637	0.1540	Yes
41	NUP88	828	2.596	0.1551	Yes
42	KPNA2	855	2.577	0.1577	Yes
43	NUP54	865	2.571	0.1613	Yes
44	BNIP2	887	2.559	0.1641	Yes
45	GTF2H1	972	2.502	0.1634	Yes
46	HNRPH1	975	2.499	0.1672	Yes
47	XRCC6	976	2.499	0.1711	Yes
48	CCNT1	977	2.498	0.1750	Yes
49	HNRPM	1012	2.479	0.1770	Yes
50	NCL	1029	2.462	0.1800	Yes
51	OIP5	1050	2.449	0.1827	Yes
52	SFRS2	1068	2.439	0.1856	Yes
53	ANAPC4	1093	2.423	0.1880	Yes
54	TOPORS	1122	2.407	0.1903	Yes
55	ING2	1126	2.402	0.1939	Yes
56	GIT2	1141	2.391	0.1968	Yes
57	RBM39	1144	2.390	0.2005	Yes
58	SUMO1	1156	2.384	0.2036	Yes
59	MORF4L2	1167	2.380	0.2067	Yes
60	SAP18	1179	2.371	0.2098	Yes
61	DDX21	1195	2.360	0.2127	Yes
62	PCGF6	1204	2.356	0.2159	Yes
63	WRN	1224	2.343	0.2186	Yes
64	INTS6	1251	2.327	0.2208	Yes
65	SF3A3	1282	2.311	0.2227	Yes
66	COPS2	1290	2.302	0.2259	Yes
67	RB1	1293	2.301	0.2294	Yes
68	SREBF1	1309	2.294	0.2322	Yes
69	SMC3	1328	2.281	0.2348	Yes
70	ATXN3	1364	2.261	0.2364	Yes
71	RBBP5	1374	2.254	0.2394	Yes
72	NBN	1390	2.246	0.2421	Yes
73	RPA1	1435	2.221	0.2431	Yes
74	ARID1A	1460	2.208	0.2453	Yes
75	ERCC4	1490	2.190	0.2471	Yes
76	SENP2	1555	2.151	0.2469	Yes
77	PHF5A	1556	2.150	0.2503	Yes
78	RANBP2	1568	2.144	0.2530	Yes
79	GTF3C2	1575	2.142	0.2561	Yes
80	HNRPDL	1592	2.135	0.2585	Yes
81	EXOSC1	1612	2.122	0.2608	Yes
82	POLR3K	1615	2.120	0.2640	Yes
83	HSPD1	1622	2.116	0.2670	Yes
84	NUP160	1660	2.095	0.2682	Yes
85	NSUN2	1710	2.069	0.2687	Yes
86	POLQ	1762	2.044	0.2691	Yes
87	NAP1L1	1789	2.032	0.2709	Yes
88	SMARCE1	1796	2.028	0.2737	Yes
89	CDKN2A	1811	2.022	0.2761	Yes
90	NUP50	1881	1.980	0.2754	Yes
91	RAD51	1890	1.978	0.2781	Yes
92	MATR3	1929	1.952	0.2790	Yes
93	LIG4	1950	1.938	0.2809	Yes
94	HNRPK	1954	1.937	0.2838	Yes
95	HNRPUL1	1959	1.935	0.2866	Yes
96	SMARCA4	1963	1.934	0.2895	Yes
97	TOP2A	1966	1.933	0.2924	Yes
98	MED12	1968	1.932	0.2953	Yes
99	NAP1L4	2012	1.914	0.2960	Yes
100	SMARCC1	2014	1.911	0.2989	Yes
101	BARD1	2026	1.904	0.3013	Yes
102	GTF3C1	2050	1.891	0.3030	Yes
103	TBP	2064	1.880	0.3052	Yes
104	NCOA6	2081	1.874	0.3072	Yes
105	ZRSR2	2097	1.865	0.3093	Yes
106	ACTL6A	2163	1.832	0.3086	Yes
107	EZH2	2166	1.831	0.3114	Yes
108	KRR1	2174	1.828	0.3138	Yes
109	NOD2	2179	1.826	0.3165	Yes
110	NFYA	2205	1.818	0.3179	Yes
111	ASF1A	2223	1.808	0.3198	Yes
112	RTCD1	2239	1.800	0.3218	Yes
113	NUP133	2257	1.791	0.3237	Yes
114	CPSF1	2268	1.786	0.3259	Yes
115	ILF2	2295	1.772	0.3273	Yes
116	SNUPN	2304	1.768	0.3296	Yes
117	XRCC4	2390	1.726	0.3276	Yes
118	ASCC3L1	2456	1.696	0.3267	Yes
119	XPO7	2458	1.696	0.3293	Yes
120	MSH6	2482	1.685	0.3306	Yes
121	IVNS1ABP	2484	1.685	0.3332	Yes
122	ASH2L	2493	1.681	0.3354	Yes
123	WDHD1	2495	1.681	0.3380	Yes
124	SF3B3	2497	1.680	0.3406	Yes
125	PRPF8	2524	1.668	0.3417	Yes
126	RPA3	2554	1.655	0.3427	Yes
127	TRIM27	2564	1.651	0.3448	Yes
128	MRE11A	2568	1.648	0.3472	Yes
129	IKBKAP	2583	1.643	0.3490	Yes
130	DDX47	2591	1.640	0.3512	Yes
131	KLHL7	2598	1.637	0.3534	Yes
132	MKI67IP	2602	1.634	0.3558	Yes
133	PRICKLE1	2652	1.606	0.3556	Yes
134	MSH3	2664	1.600	0.3575	Yes
135	TAF11	2697	1.587	0.3582	Yes
136	HMGB2	2708	1.582	0.3602	Yes
137	SDAD1	2717	1.579	0.3622	Yes
138	BNIP3L	2726	1.573	0.3642	Yes
139	HDAC1	2744	1.567	0.3657	Yes
140	HTATIP2	2745	1.566	0.3682	Yes
141	RANBP5	2790	1.545	0.3682	Yes
142	ANAPC5	2812	1.535	0.3694	Yes
143	UBTF	2818	1.532	0.3715	Yes
144	ERCC5	2849	1.518	0.3723	Yes
145	SNRPA1	2935	1.483	0.3699	Yes
146	SF3B2	2946	1.478	0.3717	Yes
147	TCOF1	2955	1.475	0.3735	Yes
148	TMPO	2980	1.460	0.3745	Yes
149	ARNTL	3076	1.419	0.3715	No
150	PTGES3	3160	1.389	0.3691	No
151	SNW1	3194	1.372	0.3694	No
152	YEATS4	3227	1.360	0.3698	No
153	NLRP5	3268	1.340	0.3697	No
154	SAP30	3273	1.339	0.3715	No
155	FUSIP1	3288	1.334	0.3729	No
156	ZNF346	3402	1.291	0.3687	No
157	PHF12	3462	1.268	0.3674	No
158	SMG6	3512	1.250	0.3667	No
159	TIPIN	3525	1.244	0.3680	No
160	SF3A1	3538	1.237	0.3692	No
161	MED4	3561	1.228	0.3699	No
162	TOPBP1	3568	1.224	0.3715	No
163	SNRPD3	3588	1.216	0.3724	No
164	MYO6	3614	1.208	0.3729	No
165	RPS7	3639	1.200	0.3734	No
166	HNRPH2	3700	1.174	0.3720	No
167	XRN2	3728	1.163	0.3723	No
168	EFTUD2	3755	1.156	0.3727	No
169	RANGAP1	3882	1.109	0.3675	No
170	ERCC3	3940	1.088	0.3661	No
171	LMNB1	3967	1.076	0.3663	No
172	EMG1	4002	1.065	0.3661	No
173	UBE2I	4008	1.062	0.3675	No
174	SHFM1	4023	1.056	0.3684	No
175	ELF4	4026	1.055	0.3699	No
176	CIRH1A	4071	1.038	0.3691	No
177	PURB	4143	1.019	0.3668	No
178	PPARGC1B	4159	1.013	0.3676	No
179	HCLS1	4173	1.009	0.3684	No
180	RPP38	4205	1.000	0.3683	No
181	MED6	4236	0.990	0.3682	No
182	EDF1	4240	0.989	0.3696	No
183	SNRPF	4242	0.989	0.3711	No
184	PITX2	4263	0.981	0.3715	No
185	NUP153	4317	0.964	0.3701	No
186	ARID4A	4351	0.953	0.3698	No
187	NPM2	4359	0.950	0.3709	No
188	SMUG1	4374	0.946	0.3716	No
189	NUTF2	4409	0.936	0.3712	No
190	SNAPC4	4420	0.931	0.3721	No
191	POLR1E	4496	0.908	0.3694	No
192	WTAP	4510	0.905	0.3701	No
193	PPARGC1A	4538	0.893	0.3700	No
194	MEN1	4612	0.866	0.3673	No
195	PURA	4614	0.866	0.3686	No
196	NFYC	4634	0.858	0.3689	No
197	MRPL19	4676	0.847	0.3680	No
198	CDC23	4716	0.834	0.3671	No
199	SNRPD1	4846	0.803	0.3613	No
200	SIP1	4875	0.797	0.3610	No
201	RPL3	4960	0.767	0.3576	No
202	COIL	5012	0.753	0.3560	No
203	NR6A1	5098	0.723	0.3524	No
204	POLI	5144	0.709	0.3511	No
205	ZNF148	5145	0.708	0.3522	No
206	GTF3C5	5151	0.708	0.3530	No
207	PTF1A	5189	0.697	0.3520	No
208	LRPPRC	5226	0.687	0.3511	No
209	GTF2H4	5244	0.683	0.3513	No
210	NF2	5247	0.682	0.3522	No
211	DDX56	5256	0.679	0.3529	No
212	GTF3C3	5293	0.667	0.3519	No
213	TAF9	5317	0.660	0.3517	No
214	ELP3	5342	0.651	0.3514	No
215	DYRK1A	5380	0.637	0.3503	No
216	CLOCK	5449	0.620	0.3476	No
217	SNRPG	5484	0.612	0.3467	No
218	PAX8	5649	0.567	0.3385	No
219	HDAC11	5656	0.562	0.3391	No
220	CPSF3	5754	0.536	0.3346	No
221	NAP1L2	5764	0.534	0.3349	No
222	PTBP1	5807	0.523	0.3334	No
223	CHEK1	5824	0.517	0.3334	No
224	GTF2F1	5857	0.510	0.3324	No
225	PHF21A	5923	0.494	0.3296	No
226	CBX1	6075	0.458	0.3220	No
227	RPP30	6131	0.444	0.3197	No
228	NOL5A	6224	0.416	0.3153	No
229	PRPF31	6275	0.405	0.3132	No
230	KPNA3	6286	0.403	0.3132	No
231	NOLC1	6409	0.371	0.3071	No
232	HDAC8	6431	0.367	0.3065	No
233	TUBG1	6454	0.363	0.3059	No
234	RAE1	6555	0.339	0.3009	No
235	PAM	6667	0.310	0.2953	No
236	RELA	6756	0.290	0.2909	No
237	SNRPB2	6885	0.260	0.2843	No
238	DDX11	6943	0.244	0.2816	No
239	SURF6	6960	0.241	0.2811	No
240	TAF4	7105	0.211	0.2735	No
241	PSEN1	7165	0.200	0.2705	No
242	PTGER3	7369	0.148	0.2596	No
243	DDX19B	7426	0.137	0.2567	No
244	CENPF	7488	0.120	0.2536	No
245	HNRPF	7505	0.115	0.2529	No
246	DHX8	7547	0.110	0.2508	No
247	RPL11	7587	0.100	0.2488	No
248	SP100	7704	0.075	0.2426	No
249	XPO1	7732	0.068	0.2412	No
250	CHAF1A	7753	0.064	0.2402	No
251	H2AFY	7796	0.055	0.2380	No
252	NPC1	8067	-0.010	0.2231	No
253	POLR2A	8070	-0.010	0.2230	No
254	CDK9	8160	-0.030	0.2182	No
255	ELL2	8163	-0.031	0.2181	No
256	ELP4	8173	-0.033	0.2177	No
257	MCM3	8379	-0.078	0.2065	No
258	SMARCD2	8382	-0.079	0.2066	No
259	PRM2	8520	-0.111	0.1992	No
260	HDAC10	8651	-0.134	0.1923	No
261	BCAS2	8726	-0.149	0.1884	No
262	RCC1	8994	-0.206	0.1741	No
263	EXOSC3	9046	-0.218	0.1716	No
264	NPAS2	9066	-0.222	0.1709	No
265	TP53	9109	-0.232	0.1690	No
266	PPP1R9B	9138	-0.238	0.1678	No
267	NCR1	9264	-0.268	0.1613	No
268	CHAF1B	9386	-0.291	0.1552	No
269	MSH2	9439	-0.304	0.1528	No
270	SNRP70	9454	-0.307	0.1525	No
271	POLR3C	9513	-0.322	0.1498	No
272	GEMIN5	9578	-0.336	0.1468	No
273	NOL1	9678	-0.355	0.1419	No
274	LSM4	9719	-0.364	0.1403	No
275	POLA1	9772	-0.374	0.1380	No
276	STAG3	9827	-0.383	0.1356	No
277	CIB1	9964	-0.407	0.1288	No
278	DNAJB9	9999	-0.414	0.1276	No
279	TERT	10006	-0.414	0.1279	No
280	RUVBL1	10106	-0.434	0.1231	No
281	PHB	10136	-0.439	0.1222	No
282	DDX24	10352	-0.481	0.1112	No
283	SF3B4	10401	-0.489	0.1093	No
284	TFIP11	10505	-0.510	0.1044	No
285	SUV39H1	10507	-0.510	0.1052	No
286	NPM1	10521	-0.513	0.1053	No
287	U2AF1	10586	-0.525	0.1026	No
288	POLR2J	10626	-0.533	0.1012	No
289	NOL3	10680	-0.540	0.0992	No
290	TDG	10835	-0.570	0.0916	No
291	BRCA1	10914	-0.586	0.0882	No
292	TAF6L	10964	-0.596	0.0865	No
293	EXOSC10	10974	-0.598	0.0869	No
294	LMO4	10975	-0.599	0.0878	No
295	PDCD7	11029	-0.608	0.0859	No
296	HIPK2	11106	-0.624	0.0827	No
297	NDUFA13	11163	-0.635	0.0806	No
298	PPIH	11214	-0.645	0.0788	No
299	FOXC1	11256	-0.653	0.0776	No
300	JUN	11297	-0.660	0.0764	No
301	RPL36	11313	-0.664	0.0767	No
302	NUDT21	11330	-0.666	0.0768	No
303	FOXF2	11412	-0.679	0.0734	No
304	IPO7	11540	-0.702	0.0675	No
305	GEMIN6	11573	-0.707	0.0669	No
306	NRM	11581	-0.708	0.0676	No
307	TXNL4A	11769	-0.735	0.0585	No
308	HDAC9	11899	-0.760	0.0526	No
309	FIGLA	12083	-0.796	0.0438	No
310	ZBTB16	12115	-0.800	0.0433	No
311	SLC29A2	12137	-0.804	0.0434	No
312	CDC26	12232	-0.823	0.0395	No
313	HIF1A	12383	-0.849	0.0326	No
314	GUCY2F	12411	-0.853	0.0325	No
315	TIMELESS	12455	-0.862	0.0314	No
316	PARP1	12470	-0.865	0.0320	No
317	DULLARD	12656	-0.899	0.0233	No
318	RRP9	12690	-0.904	0.0229	No
319	MPHOSPH10	12693	-0.905	0.0242	No
320	NOL4	12966	-0.957	0.0107	No
321	TIMM50	13028	-0.966	0.0089	No
322	HOXC10	13030	-0.966	0.0103	No
323	EXOSC9	13113	-0.982	0.0074	No
324	RALY	13132	-0.985	0.0079	No
325	NOLA3	13226	-1.005	0.0044	No
326	TTN	13315	-1.022	0.0011	No
327	OGG1	13338	-1.028	0.0015	No
328	TEP1	13369	-1.032	0.0015	No
329	SPTBN4	13415	-1.042	0.0006	No
330	ASNA1	13432	-1.045	0.0014	No
331	DDX54	13643	-1.085	-0.0085	No
332	RPL35	13655	-1.087	-0.0074	No
333	GRINL1A	13784	-1.110	-0.0127	No
334	BNIP3	13886	-1.129	-0.0165	No
335	MCM7	13889	-1.130	-0.0148	No
336	TAF12	13929	-1.139	-0.0152	No
337	DMC1	14017	-1.155	-0.0181	No
338	NAP1L3	14143	-1.183	-0.0232	No
339	NXT1	14303	-1.221	-0.0300	No
340	AAAS	14316	-1.224	-0.0287	No
341	MPG	14322	-1.226	-0.0271	No
342	FOXE3	14378	-1.238	-0.0282	No
343	WDR4	14594	-1.284	-0.0380	No
344	RGS12	14646	-1.294	-0.0388	No
345	GEMIN4	14675	-1.299	-0.0383	No
346	LRCH4	14691	-1.302	-0.0371	No
347	HDAC7A	14737	-1.310	-0.0375	No
348	DHCR7	14753	-1.315	-0.0363	No
349	APTX	14787	-1.323	-0.0360	No
350	EPAS1	14825	-1.330	-0.0360	No
351	HDAC3	14846	-1.334	-0.0350	No
352	FGF18	14848	-1.335	-0.0330	No
353	TAF6	15070	-1.388	-0.0429	No
354	HDAC5	15100	-1.394	-0.0424	No
355	REPIN1	15114	-1.398	-0.0409	No
356	NKX2-5	15168	-1.408	-0.0416	No
357	SCRN1	15175	-1.410	-0.0397	No
358	SRP68	15249	-1.428	-0.0415	No
359	PMF1	15252	-1.430	-0.0394	No
360	BNIP1	15276	-1.435	-0.0384	No
361	NOL6	15333	-1.446	-0.0392	No
362	RPS19	15387	-1.460	-0.0398	No
363	NUFIP1	15410	-1.467	-0.0388	No
364	IFI16	15488	-1.490	-0.0407	No
365	CHMP1A	15536	-1.502	-0.0409	No
366	TAF7	15541	-1.503	-0.0388	No
367	HDAC6	15596	-1.516	-0.0394	No
368	ATXN1	15736	-1.552	-0.0446	No
369	KLHDC3	15825	-1.579	-0.0470	No
370	POLR2B	15913	-1.604	-0.0492	No
371	FZR1	15961	-1.618	-0.0493	No
372	NUP62	15969	-1.622	-0.0471	No
373	RUVBL2	16166	-1.673	-0.0553	No
374	HES6	16223	-1.689	-0.0557	No
375	POLR2E	16231	-1.691	-0.0535	No
376	RBM14	16235	-1.692	-0.0510	No
377	DNMT3A	16236	-1.692	-0.0484	No
378	DEDD	16250	-1.696	-0.0464	No
379	NEK11	16518	-1.788	-0.0583	No
380	GCM1	16566	-1.807	-0.0581	No
381	SMARCD1	16587	-1.813	-0.0563	No
382	GLIS2	16675	-1.846	-0.0582	No
383	ACTB	16743	-1.871	-0.0590	No
384	ISG20	16777	-1.890	-0.0579	No
385	NOLA2	16782	-1.891	-0.0551	No
386	ATRX	16863	-1.921	-0.0565	No
387	HMGA1	16874	-1.926	-0.0541	No
388	FMR1	16887	-1.931	-0.0517	No
389	RPA2	16897	-1.935	-0.0492	No
390	U2AF2	16932	-1.950	-0.0480	No
391	TAF10	16966	-1.962	-0.0467	No
392	PML	16972	-1.966	-0.0439	No
393	RPP40	17110	-2.025	-0.0483	No
394	SNRPB	17174	-2.044	-0.0486	No
395	EIF5A	17184	-2.047	-0.0459	No
396	CBX5	17258	-2.087	-0.0466	No
397	GNAZ	17396	-2.157	-0.0508	No
398	SMARCD3	17416	-2.166	-0.0484	No
399	MCRS1	17465	-2.191	-0.0477	No
400	EMD	17466	-2.191	-0.0442	No
401	THRAP3	17500	-2.213	-0.0426	No
402	SNRPA	17563	-2.253	-0.0425	No
403	SNRPD2	17606	-2.276	-0.0412	No
404	POP7	17627	-2.289	-0.0388	No
405	ERCC2	17727	-2.361	-0.0405	No
406	POLR3H	17834	-2.450	-0.0425	No
407	ERCC1	17895	-2.491	-0.0419	No
408	SF3A2	17948	-2.545	-0.0408	No
409	ANAPC11	17954	-2.548	-0.0371	No
410	DEDD2	18004	-2.599	-0.0357	No
411	MYBBP1A	18246	-2.917	-0.0444	No
412	GEMIN7	18249	-2.923	-0.0400	No
413	HRB	18373	-3.167	-0.0418	No
414	POP1	18391	-3.203	-0.0377	No
415	HTATIP	18410	-3.244	-0.0336	No
416	ABL1	18411	-3.245	-0.0285	No
417	RBPJ	18441	-3.325	-0.0249	No
418	NUP98	18447	-3.340	-0.0200	No
419	ERCC8	18474	-3.406	-0.0161	No
420	BRE	18475	-3.412	-0.0108	No
421	SMARCB1	18477	-3.434	-0.0055	No
422	BCL2	18546	-3.877	-0.0031	No
423	PSEN2	18592	-4.440	0.0013	No