Details for gene set HUMAN_MITODB_6

Table: GSEA Results Summary

Dataset	set03_wtNotch_versus_normalThy
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	HUMAN_MITODB_6_2002
Enrichment Score (ES)	0.45022258
Normalized Enrichment Score (NES)	2.2025483
Nominal p-value	0.0
FDR q-value	2.8845237E-4
FWER p-Value	0.0040

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SHMT2	32	7.432	0.0088	Yes
2	ABCB6	35	7.229	0.0189	Yes
3	BAX	38	6.993	0.0287	Yes
4	TIMM10	44	6.849	0.0381	Yes
5	MRPS10	59	6.411	0.0464	Yes
6	ENDOG	89	5.857	0.0531	Yes
7	MRPS18B	90	5.832	0.0614	Yes
8	GOT2	92	5.775	0.0695	Yes
9	SOD2	112	5.520	0.0762	Yes
10	TIMM13	118	5.483	0.0837	Yes
11	COX5A	137	5.239	0.0902	Yes
12	MRPL11	138	5.236	0.0976	Yes
13	DHODH	150	5.137	0.1042	Yes
14	TXNRD2	162	5.034	0.1108	Yes
15	CYC1	173	4.902	0.1171	Yes
16	IMMT	182	4.852	0.1236	Yes
17	ACAA2	188	4.799	0.1301	Yes
18	NDUFA10	194	4.757	0.1365	Yes
19	ATP5G1	202	4.726	0.1429	Yes
20	MRPS7	208	4.689	0.1492	Yes
21	CLPP	210	4.682	0.1558	Yes
22	TOMM40	218	4.634	0.1620	Yes
23	SLC25A3	234	4.571	0.1676	Yes
24	MRPS15	259	4.452	0.1726	Yes
25	MRPS30	267	4.434	0.1785	Yes
26	ETFB	281	4.358	0.1839	Yes
27	MRPS28	288	4.334	0.1897	Yes
28	IDH3A	307	4.288	0.1948	Yes
29	RPS3A	386	3.975	0.1962	Yes
30	HSPD1	415	3.873	0.2001	Yes
31	MRPL12	419	3.849	0.2054	Yes
32	PMPCB	427	3.826	0.2104	Yes
33	SHMT1	434	3.820	0.2155	Yes
34	FPGS	451	3.774	0.2200	Yes
35	DLD	461	3.746	0.2248	Yes
36	ATP5G2	485	3.705	0.2288	Yes
37	NDUFB8	495	3.672	0.2335	Yes
38	ACADL	505	3.635	0.2381	Yes
39	ETFA	540	3.558	0.2413	Yes
40	SLC25A17	545	3.545	0.2461	Yes
41	SUPV3L1	547	3.543	0.2511	Yes
42	BCS1L	563	3.501	0.2552	Yes
43	MTCH2	567	3.494	0.2600	Yes
44	UQCRC1	568	3.493	0.2649	Yes
45	DNM1L	578	3.463	0.2693	Yes
46	ACADS	593	3.424	0.2734	Yes
47	SDHB	594	3.417	0.2782	Yes
48	MRPL4	596	3.416	0.2830	Yes
49	MRPL13	604	3.399	0.2875	Yes
50	ABCF2	615	3.369	0.2917	Yes
51	HLCS	629	3.326	0.2957	Yes
52	MRPL19	647	3.287	0.2994	Yes
53	MRPS27	663	3.251	0.3032	Yes
54	MRPS18A	668	3.244	0.3075	Yes
55	MRPS11	695	3.185	0.3106	Yes
56	ACAT1	696	3.182	0.3151	Yes
57	COQ7	721	3.136	0.3182	Yes
58	BID	751	3.087	0.3210	Yes
59	FDXR	766	3.067	0.3246	Yes
60	GOT1	780	3.042	0.3282	Yes
61	TOMM22	836	2.951	0.3294	Yes
62	SLC25A10	945	2.804	0.3274	Yes
63	COX15	949	2.798	0.3312	Yes
64	MRPS2	963	2.787	0.3344	Yes
65	MRPS35	964	2.787	0.3384	Yes
66	MTCH1	972	2.775	0.3419	Yes
67	MDH2	1021	2.727	0.3432	Yes
68	DBT	1063	2.689	0.3447	Yes
69	NDUFA8	1066	2.688	0.3484	Yes
70	GSR	1074	2.681	0.3518	Yes
71	ATP5E	1097	2.652	0.3544	Yes
72	PCCB	1121	2.623	0.3568	Yes
73	NDUFB4	1134	2.608	0.3599	Yes
74	RPL3	1229	2.528	0.3583	Yes
75	ABCB7	1335	2.414	0.3560	Yes
76	MRPL22	1378	2.378	0.3570	Yes
77	SLC25A1	1379	2.378	0.3604	Yes
78	TK1	1380	2.378	0.3638	Yes
79	CYCS	1401	2.360	0.3660	Yes
80	MRPS18C	1428	2.337	0.3679	Yes
81	FIBP	1471	2.304	0.3688	Yes
82	OPA1	1488	2.293	0.3712	Yes
83	MRPL48	1506	2.283	0.3735	Yes
84	ATP5G3	1512	2.282	0.3765	Yes
85	SURF1	1521	2.278	0.3793	Yes
86	ATP7B	1558	2.249	0.3805	Yes
87	MRPS34	1582	2.232	0.3824	Yes
88	PPID	1593	2.224	0.3850	Yes
89	SLC25A13	1606	2.217	0.3874	Yes
90	CPT2	1615	2.212	0.3901	Yes
91	VDAC2	1627	2.208	0.3927	Yes
92	NDUFS7	1656	2.186	0.3942	Yes
93	TXN2	1658	2.185	0.3973	Yes
94	TRAP1	1659	2.184	0.4003	Yes
95	TIMM17A	1661	2.183	0.4034	Yes
96	GLUD1	1676	2.172	0.4057	Yes
97	MTRF1	1685	2.167	0.4083	Yes
98	ATP5S	1694	2.162	0.4109	Yes
99	PYCR1	1725	2.144	0.4123	Yes
100	TOMM70A	1766	2.121	0.4131	Yes
101	AK2	1819	2.089	0.4133	Yes
102	PDHB	1821	2.088	0.4162	Yes
103	VDAC3	1826	2.080	0.4189	Yes
104	NDUFC1	1858	2.064	0.4201	Yes
105	UQCR	1874	2.054	0.4222	Yes
106	COX10	1906	2.037	0.4234	Yes
107	HTATSF1	1947	2.012	0.4240	Yes
108	MRPL34	1989	1.992	0.4246	Yes
109	GCAT	2025	1.970	0.4255	Yes
110	PDK4	2076	1.949	0.4255	Yes
111	COX6A2	2081	1.944	0.4280	Yes
112	MRPL16	2124	1.927	0.4285	Yes
113	ACAD8	2150	1.909	0.4298	Yes
114	NDUFB5	2198	1.883	0.4299	Yes
115	MRPL20	2267	1.853	0.4288	Yes
116	ECHS1	2314	1.832	0.4289	Yes
117	MAOA	2325	1.826	0.4309	Yes
118	MRPL46	2336	1.821	0.4329	Yes
119	GPT	2349	1.814	0.4348	Yes
120	ACADVL	2382	1.802	0.4356	Yes
121	MRPS12	2483	1.749	0.4326	Yes
122	ACP6	2490	1.745	0.4348	Yes
123	ATP5D	2522	1.729	0.4355	Yes
124	AKAP1	2523	1.729	0.4380	Yes
125	ACO2	2536	1.725	0.4397	Yes
126	ALDH2	2547	1.719	0.4416	Yes
127	MBD3	2565	1.710	0.4431	Yes
128	TIMM23	2566	1.710	0.4455	Yes
129	SLC25A4	2741	1.631	0.4383	Yes
130	ATP5F1	2805	1.609	0.4372	Yes
131	GPX4	2822	1.603	0.4385	Yes
132	TUFM	2864	1.589	0.4385	Yes
133	NDUFAB1	2929	1.565	0.4373	Yes
134	MTHFD1	2967	1.551	0.4374	Yes
135	ATP5C1	2990	1.541	0.4384	Yes
136	MFN1	2991	1.541	0.4406	Yes
137	NME4	3033	1.530	0.4405	Yes
138	OAT	3053	1.521	0.4416	Yes
139	UQCRB	3055	1.521	0.4437	Yes
140	BLVRA	3061	1.519	0.4456	Yes
141	TIMM8A	3096	1.506	0.4459	Yes
142	IDH3B	3152	1.484	0.4450	Yes
143	GATM	3191	1.470	0.4450	Yes
144	COX5B	3201	1.468	0.4465	Yes
145	SUCLA2	3217	1.464	0.4478	Yes
146	NR3C1	3247	1.453	0.4483	Yes
147	HSD3B2	3258	1.449	0.4498	Yes
148	FECH	3346	1.414	0.4470	Yes
149	SDHD	3348	1.413	0.4489	Yes
150	CLN3	3362	1.408	0.4502	Yes
151	SUCLG1	3530	1.354	0.4430	No
152	ETFDH	3545	1.350	0.4441	No
153	MPST	3557	1.346	0.4454	No
154	HSPE1	3571	1.343	0.4466	No
155	AMT	3609	1.332	0.4465	No
156	NDUFA6	3615	1.331	0.4481	No
157	PDHX	3621	1.330	0.4497	No
158	MRPS31	3683	1.309	0.4482	No
159	CNOT7	3775	1.284	0.4451	No
160	NFS1	3789	1.281	0.4462	No
161	NDUFS2	3794	1.278	0.4477	No
162	SDHC	3909	1.238	0.4433	No
163	NDUFC2	3936	1.232	0.4436	No
164	DLAT	3947	1.228	0.4448	No
165	NDUFB7	3966	1.223	0.4455	No
166	UCP3	3995	1.216	0.4457	No
167	PDHA1	4004	1.213	0.4470	No
168	MRPS17	4011	1.212	0.4484	No
169	IVNS1ABP	4052	1.199	0.4479	No
170	ATP5O	4080	1.191	0.4481	No
171	BAK1	4139	1.175	0.4466	No
172	NDUFS8	4177	1.165	0.4462	No
173	MRPS14	4326	1.129	0.4397	No
174	ATP5J	4340	1.126	0.4406	No
175	MTERF	4363	1.122	0.4409	No
176	BAD	4407	1.108	0.4402	No
177	GALR3	4486	1.089	0.4374	No
178	PIN4	4539	1.076	0.4361	No
179	CYP27B1	4627	1.055	0.4328	No
180	POPDC2	4667	1.045	0.4322	No
181	HAX1	4723	1.032	0.4306	No
182	MRPL33	4824	1.009	0.4266	No
183	MFN2	4917	0.988	0.4229	No
184	MRPL9	5041	0.960	0.4176	No
185	COX7B	5144	0.933	0.4133	No
186	ALAS1	5145	0.933	0.4146	No
187	HADHB	5176	0.925	0.4143	No
188	MRPL17	5244	0.907	0.4119	No
189	GRID2	5308	0.890	0.4097	No
190	MRPL35	5335	0.880	0.4095	No
191	POLG2	5412	0.862	0.4066	No
192	MAOB	5417	0.860	0.4076	No
193	ATP5I	5475	0.848	0.4057	No
194	CLPX	5479	0.848	0.4067	No
195	TAT	5615	0.817	0.4005	No
196	CYP27A1	5616	0.817	0.4016	No
197	CS	5656	0.810	0.4006	No
198	PET112L	5760	0.782	0.3961	No
199	DECR1	5806	0.774	0.3947	No
200	BCKDK	5975	0.738	0.3866	No
201	CPT1B	5986	0.735	0.3871	No
202	AGXT	6062	0.717	0.3840	No
203	HCLS1	6090	0.713	0.3835	No
204	TIMM9	6130	0.705	0.3824	No
205	SLC25A5	6145	0.703	0.3826	No
206	SDS	6170	0.697	0.3823	No
207	PDK3	6193	0.691	0.3820	No
208	OGG1	6448	0.637	0.3690	No
209	DLST	6498	0.629	0.3672	No
210	COX6C	6550	0.619	0.3653	No
211	SLC1A3	6563	0.617	0.3655	No
212	CYBA	6577	0.614	0.3657	No
213	SLC25A20	6643	0.600	0.3630	No
214	HADHA	6687	0.592	0.3615	No
215	MTIF2	6935	0.543	0.3487	No
216	PCCA	6952	0.540	0.3486	No
217	NDUFA5	6967	0.537	0.3486	No
218	NDUFB2	6973	0.535	0.3491	No
219	CRY1	6997	0.530	0.3486	No
220	UQCRFS1	7023	0.524	0.3479	No
221	BNIP3L	7206	0.487	0.3387	No
222	PRDX3	7212	0.484	0.3391	No
223	MRPS16	7217	0.483	0.3395	No
224	NDUFA9	7272	0.470	0.3373	No
225	CKMT2	7331	0.458	0.3347	No
226	SARDH	7367	0.451	0.3335	No
227	MRPS22	7418	0.441	0.3313	No
228	MTHFD2	7423	0.440	0.3317	No
229	MRPL39	7438	0.437	0.3316	No
230	LYPLA2	7471	0.430	0.3305	No
231	UQCRC2	7923	0.341	0.3062	No
232	IDH3G	8083	0.307	0.2980	No
233	TIMM22	8126	0.298	0.2961	No
234	HCCS	8128	0.297	0.2965	No
235	SLC25A28	8260	0.270	0.2897	No
236	OTC	8283	0.264	0.2888	No
237	SLC25A15	8638	0.197	0.2697	No
238	GCDH	8652	0.194	0.2693	No
239	ODC1	8937	0.137	0.2539	No
240	NDUFS5	9118	0.105	0.2442	No
241	CASP8	9176	0.093	0.2412	No
242	MRPL18	9378	0.052	0.2303	No
243	TOMM20	9406	0.048	0.2289	No
244	CYP11B2	9425	0.043	0.2280	No
245	HSD3B1	9529	0.020	0.2224	No
246	NDUFA7	9541	0.018	0.2218	No
247	IDH2	9687	-0.009	0.2139	No
248	PPIF	9807	-0.029	0.2074	No
249	ATP5J2	9860	-0.041	0.2046	No
250	GLYAT	10302	-0.130	0.1806	No
251	SDHA	10362	-0.140	0.1776	No
252	HMGCS2	10557	-0.180	0.1672	No
253	HK1	10601	-0.191	0.1652	No
254	AFG3L2	10623	-0.198	0.1643	No
255	BCKDHB	10656	-0.205	0.1628	No
256	COX7C	10665	-0.207	0.1627	No
257	PPM2C	10836	-0.241	0.1537	No
258	RPLP2	10960	-0.267	0.1474	No
259	ATPIF1	11000	-0.279	0.1456	No
260	BCKDHA	11247	-0.328	0.1326	No
261	CPT1A	11693	-0.425	0.1088	No
262	MRPL15	11756	-0.442	0.1061	No
263	CASQ1	11793	-0.450	0.1047	No
264	GCK	11905	-0.472	0.0993	No
265	MRPL44	11935	-0.476	0.0984	No
266	MUT	11987	-0.484	0.0963	No
267	COX11	12078	-0.507	0.0921	No
268	PPOX	12093	-0.511	0.0921	No
269	MIPEP	12117	-0.516	0.0915	No
270	ABAT	12204	-0.533	0.0876	No
271	DNASE2	12215	-0.537	0.0878	No
272	ATP5H	12426	-0.587	0.0771	No
273	ALDH4A1	12570	-0.621	0.0702	No
274	LARS2	12583	-0.625	0.0704	No
275	POLRMT	12593	-0.628	0.0708	No
276	COX4I1	12616	-0.632	0.0705	No
277	GPD2	12712	-0.655	0.0662	No
278	BNIP3	12999	-0.719	0.0516	No
279	STARD3	13184	-0.771	0.0426	No
280	APAF1	13413	-0.827	0.0313	No
281	FDX1	13414	-0.827	0.0324	No
282	NDUFB3	13417	-0.828	0.0335	No
283	COX7A1	13427	-0.829	0.0342	No
284	SLC9A6	13447	-0.835	0.0343	No
285	FRAP1	13448	-0.835	0.0355	No
286	TIMM17B	13468	-0.840	0.0357	No
287	TFB1M	13472	-0.842	0.0367	No
288	NDUFA4	13684	-0.895	0.0264	No
289	TIMM44	13979	-0.982	0.0117	No
290	CRAT	14063	-1.001	0.0086	No
291	TIMM8B	14121	-1.019	0.0069	No
292	COX6A1	14255	-1.060	0.0011	No
293	ME2	14265	-1.064	0.0021	No
294	SLC25A12	14299	-1.075	0.0018	No
295	COX7A2	14304	-1.077	0.0031	No
296	MUTYH	14426	-1.111	-0.0019	No
297	ATP5B	14686	-1.194	-0.0144	No
298	TST	14784	-1.230	-0.0180	No
299	DAP3	14840	-1.253	-0.0192	No
300	AMACR	14906	-1.277	-0.0210	No
301	MRPS33	14982	-1.308	-0.0232	No
302	NDUFS3	15097	-1.356	-0.0276	No
303	STAR	15203	-1.402	-0.0313	No
304	SPG7	15204	-1.403	-0.0293	No
305	HSPA1L	15247	-1.421	-0.0296	No
306	NDUFA2	15344	-1.467	-0.0328	No
307	OGDH	15383	-1.486	-0.0328	No
308	UQCRH	15411	-1.506	-0.0321	No
309	SLC25A16	15419	-1.510	-0.0304	No
310	TOMM34	15458	-1.530	-0.0303	No
311	CYP24A1	15588	-1.603	-0.0351	No
312	ACADSB	15609	-1.613	-0.0339	No
313	ARG2	15612	-1.614	-0.0317	No
314	NNT	15616	-1.616	-0.0296	No
315	PDK1	15809	-1.722	-0.0377	No
316	HMGCL	15879	-1.761	-0.0390	No
317	UCP1	15908	-1.778	-0.0380	No
318	RAF1	15947	-1.805	-0.0375	No
319	MRP63	15990	-1.839	-0.0372	No
320	NDUFS1	16100	-1.909	-0.0405	No
321	SLC25A21	16152	-1.955	-0.0405	No
322	CYBB	16189	-1.976	-0.0397	No
323	SLC1A1	16347	-2.097	-0.0453	No
324	DGUOK	16481	-2.203	-0.0495	No
325	BCAT2	16540	-2.245	-0.0495	No
326	SLC25A14	16641	-2.336	-0.0516	No
327	TFAM	16658	-2.353	-0.0492	No
328	SCP2	16869	-2.578	-0.0570	No
329	NDUFS4	16892	-2.602	-0.0545	No
330	ACADM	16942	-2.663	-0.0535	No
331	NGFRAP1	16968	-2.689	-0.0510	No
332	IVD	16983	-2.705	-0.0480	No
333	BCL2L11	17107	-2.863	-0.0506	No
334	MRPL49	17154	-2.925	-0.0490	No
335	POLG	17186	-2.973	-0.0465	No
336	UROS	17222	-3.039	-0.0441	No
337	MPO	17324	-3.184	-0.0452	No
338	CYP11A1	17333	-3.202	-0.0411	No
339	COX7A2L	17349	-3.233	-0.0373	No
340	MCCC1	17353	-3.236	-0.0329	No
341	TK2	17391	-3.306	-0.0302	No
342	NDUFA3	17472	-3.455	-0.0297	No
343	AKAP10	17508	-3.523	-0.0267	No
344	BCL2L1	17522	-3.558	-0.0223	No
345	DIABLO	17625	-3.729	-0.0226	No
346	NRF1	17703	-3.905	-0.0213	No
347	PTPRA	17712	-3.927	-0.0162	No
348	MRPL24	18144	-5.272	-0.0324	No
349	WARS2	18224	-5.651	-0.0287	No
350	UCP2	18264	-5.900	-0.0225	No
351	SLC25A11	18345	-6.504	-0.0176	No
352	BCL2	18530	-9.542	-0.0142	No
353	DCI	18573	-13.334	0.0024	No