Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | set03_truncNotch_versus_wtNotch |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_DNA_REPLICATION |
| Enrichment Score (ES) | -0.5131411 |
| Normalized Enrichment Score (NES) | -2.21473 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0039343294 |
| FWER p-Value | 0.0090 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PSMD9 | 1691 | 1.948 | -0.0700 | No | ||
| 2 | RPA2 | 1719 | 1.935 | -0.0504 | No | ||
| 3 | PSMB2 | 2714 | 1.601 | -0.0866 | No | ||
| 4 | LIG1 | 3491 | 1.400 | -0.1132 | No | ||
| 5 | PSMB10 | 4161 | 1.254 | -0.1357 | No | ||
| 6 | MCM7 | 4727 | 1.130 | -0.1539 | No | ||
| 7 | RFC5 | 4981 | 1.084 | -0.1557 | No | ||
| 8 | PSMC4 | 5367 | 1.009 | -0.1655 | No | ||
| 9 | PSMB6 | 5748 | 0.939 | -0.1758 | No | ||
| 10 | PSMA7 | 5916 | 0.906 | -0.1750 | No | ||
| 11 | PSMD5 | 6081 | 0.877 | -0.1743 | No | ||
| 12 | POLD1 | 6261 | 0.843 | -0.1748 | No | ||
| 13 | PSMC1 | 6801 | 0.743 | -0.1958 | No | ||
| 14 | POLE2 | 6949 | 0.721 | -0.1958 | No | ||
| 15 | POLD2 | 7698 | 0.587 | -0.2298 | No | ||
| 16 | PSMA5 | 8161 | 0.498 | -0.2493 | No | ||
| 17 | PSMB3 | 8664 | 0.405 | -0.2719 | No | ||
| 18 | POLA1 | 8844 | 0.374 | -0.2775 | No | ||
| 19 | MCM5 | 9024 | 0.339 | -0.2835 | No | ||
| 20 | MCM2 | 9236 | 0.291 | -0.2917 | No | ||
| 21 | POLA2 | 9324 | 0.275 | -0.2934 | No | ||
| 22 | PSMB4 | 9741 | 0.181 | -0.3139 | No | ||
| 23 | MCM3 | 10237 | 0.078 | -0.3397 | No | ||
| 24 | PSMB9 | 10277 | 0.070 | -0.3411 | No | ||
| 25 | PSMB5 | 10292 | 0.067 | -0.3411 | No | ||
| 26 | PSMA6 | 10299 | 0.065 | -0.3407 | No | ||
| 27 | RFC3 | 10437 | 0.034 | -0.3477 | No | ||
| 28 | PSMD8 | 10838 | -0.059 | -0.3686 | No | ||
| 29 | PSMC3 | 10997 | -0.093 | -0.3762 | No | ||
| 30 | PSMC2 | 11717 | -0.255 | -0.4122 | No | ||
| 31 | PSMB1 | 12039 | -0.334 | -0.4258 | No | ||
| 32 | MCM10 | 12091 | -0.345 | -0.4248 | No | ||
| 33 | FEN1 | 13207 | -0.630 | -0.4781 | No | ||
| 34 | ORC2L | 13315 | -0.665 | -0.4766 | No | ||
| 35 | PSMD2 | 13539 | -0.730 | -0.4807 | No | ||
| 36 | PSME3 | 13560 | -0.736 | -0.4738 | No | ||
| 37 | PSME1 | 14286 | -0.960 | -0.5025 | Yes | ||
| 38 | PSMC5 | 14485 | -1.021 | -0.5020 | Yes | ||
| 39 | ORC1L | 14523 | -1.032 | -0.4928 | Yes | ||
| 40 | PSMD11 | 14541 | -1.037 | -0.4825 | Yes | ||
| 41 | PSMA1 | 14663 | -1.082 | -0.4772 | Yes | ||
| 42 | RFC4 | 14912 | -1.173 | -0.4778 | Yes | ||
| 43 | E2F2 | 14975 | -1.199 | -0.4682 | Yes | ||
| 44 | MCM6 | 15098 | -1.246 | -0.4612 | Yes | ||
| 45 | PSMC6 | 15180 | -1.279 | -0.4517 | Yes | ||
| 46 | GMNN | 15735 | -1.506 | -0.4652 | Yes | ||
| 47 | RPA3 | 16062 | -1.655 | -0.4648 | Yes | ||
| 48 | ORC5L | 16341 | -1.784 | -0.4604 | Yes | ||
| 49 | CDC45L | 16582 | -1.897 | -0.4527 | Yes | ||
| 50 | POLD3 | 16664 | -1.938 | -0.4360 | Yes | ||
| 51 | PSMD3 | 16879 | -2.057 | -0.4252 | Yes | ||
| 52 | PRIM1 | 16962 | -2.096 | -0.4068 | Yes | ||
| 53 | PCNA | 17091 | -2.167 | -0.3902 | Yes | ||
| 54 | RPA1 | 17181 | -2.221 | -0.3708 | Yes | ||
| 55 | RB1 | 17323 | -2.301 | -0.3534 | Yes | ||
| 56 | PSMD4 | 17477 | -2.395 | -0.3356 | Yes | ||
| 57 | CDK2 | 17488 | -2.401 | -0.3101 | Yes | ||
| 58 | PSMD7 | 17529 | -2.431 | -0.2858 | Yes | ||
| 59 | POLE | 17578 | -2.455 | -0.2617 | Yes | ||
| 60 | RFC1 | 17631 | -2.492 | -0.2374 | Yes | ||
| 61 | PSMA4 | 17660 | -2.511 | -0.2117 | Yes | ||
| 62 | PSMD10 | 17742 | -2.569 | -0.1881 | Yes | ||
| 63 | PSMA2 | 17770 | -2.581 | -0.1615 | Yes | ||
| 64 | PSMA3 | 17865 | -2.659 | -0.1377 | Yes | ||
| 65 | CDC7 | 18162 | -2.928 | -0.1218 | Yes | ||
| 66 | MCM4 | 18238 | -3.033 | -0.0929 | Yes | ||
| 67 | PSMD14 | 18296 | -3.126 | -0.0620 | Yes | ||
| 68 | PSMD12 | 18428 | -3.388 | -0.0322 | Yes | ||
| 69 | ORC4L | 18548 | -3.893 | 0.0037 | Yes |
