Dataset | set03_truncNotch_versus_normalThy |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_neg |
GeneSet | PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY |
Enrichment Score (ES) | -0.5084417 |
Normalized Enrichment Score (NES) | -1.8926111 |
Nominal p-value | 0.0 |
FDR q-value | 1.0 |
FWER p-Value | 0.682 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | MAPKAPK2 | 58 | 8.591 | 0.0158 | No | ||
2 | RIPK4 | 64 | 8.461 | 0.0341 | No | ||
3 | RPS6KA1 | 310 | 5.834 | 0.0337 | No | ||
4 | CDC42BPB | 685 | 4.386 | 0.0231 | No | ||
5 | CSNK1D | 740 | 4.252 | 0.0295 | No | ||
6 | CDK10 | 850 | 3.988 | 0.0324 | No | ||
7 | PHKG2 | 1219 | 3.346 | 0.0198 | No | ||
8 | LIMK1 | 1307 | 3.210 | 0.0222 | No | ||
9 | BCKDK | 1427 | 3.058 | 0.0225 | No | ||
10 | STK19 | 1446 | 3.038 | 0.0282 | No | ||
11 | PRKAG1 | 1456 | 3.028 | 0.0344 | No | ||
12 | MAP4K5 | 1691 | 2.784 | 0.0278 | No | ||
13 | MKNK2 | 2003 | 2.493 | 0.0164 | No | ||
14 | MARK1 | 2149 | 2.396 | 0.0139 | No | ||
15 | MAP3K10 | 2364 | 2.261 | 0.0072 | No | ||
16 | DAPK3 | 2400 | 2.236 | 0.0103 | No | ||
17 | NEK2 | 2537 | 2.158 | 0.0076 | No | ||
18 | IRAK3 | 2660 | 2.098 | 0.0056 | No | ||
19 | CDK9 | 2765 | 2.038 | 0.0045 | No | ||
20 | BRSK2 | 2816 | 2.011 | 0.0062 | No | ||
21 | TESK1 | 2912 | 1.962 | 0.0054 | No | ||
22 | TESK2 | 3031 | 1.914 | 0.0032 | No | ||
23 | RPS6KC1 | 3171 | 1.852 | -0.0003 | No | ||
24 | ACVR1B | 3237 | 1.825 | 0.0002 | No | ||
25 | BCR | 3474 | 1.735 | -0.0087 | No | ||
26 | IRAK1 | 3536 | 1.715 | -0.0083 | No | ||
27 | TSSK6 | 3751 | 1.643 | -0.0162 | No | ||
28 | RPS6KA2 | 3882 | 1.601 | -0.0198 | No | ||
29 | TTN | 3997 | 1.568 | -0.0225 | No | ||
30 | CSNK2B | 4093 | 1.540 | -0.0243 | No | ||
31 | TSSK3 | 4206 | 1.505 | -0.0270 | No | ||
32 | TSSK2 | 4589 | 1.406 | -0.0446 | No | ||
33 | NEK11 | 4620 | 1.396 | -0.0432 | No | ||
34 | MAP4K1 | 4652 | 1.388 | -0.0418 | No | ||
35 | MARK4 | 4735 | 1.368 | -0.0432 | No | ||
36 | ILK | 4833 | 1.341 | -0.0455 | No | ||
37 | MAP3K9 | 4907 | 1.321 | -0.0466 | No | ||
38 | CDK7 | 5000 | 1.297 | -0.0487 | No | ||
39 | PLK1 | 5426 | 1.189 | -0.0691 | No | ||
40 | MAST1 | 5471 | 1.173 | -0.0689 | No | ||
41 | EXOSC10 | 5695 | 1.122 | -0.0786 | No | ||
42 | PRKCZ | 5893 | 1.076 | -0.0869 | No | ||
43 | ACVRL1 | 6015 | 1.049 | -0.0911 | No | ||
44 | RPS6KA3 | 6045 | 1.042 | -0.0904 | No | ||
45 | VRK1 | 6171 | 1.016 | -0.0949 | No | ||
46 | MAP3K6 | 6399 | 0.965 | -0.1051 | No | ||
47 | MAPK13 | 6583 | 0.919 | -0.1130 | No | ||
48 | ERN2 | 6686 | 0.893 | -0.1166 | No | ||
49 | EIF2AK2 | 6696 | 0.891 | -0.1151 | No | ||
50 | MAPK10 | 6822 | 0.864 | -0.1200 | No | ||
51 | TAOK2 | 6927 | 0.840 | -0.1238 | No | ||
52 | ACVR2A | 6983 | 0.830 | -0.1249 | No | ||
53 | ACVR1C | 7058 | 0.814 | -0.1271 | No | ||
54 | MAP3K13 | 7072 | 0.811 | -0.1261 | No | ||
55 | STK3 | 7288 | 0.764 | -0.1360 | No | ||
56 | RIPK3 | 7538 | 0.714 | -0.1480 | No | ||
57 | MAPKAPK5 | 7540 | 0.713 | -0.1464 | No | ||
58 | DAPK2 | 7590 | 0.703 | -0.1476 | No | ||
59 | TTK | 7608 | 0.697 | -0.1469 | No | ||
60 | ACVR1 | 7867 | 0.645 | -0.1595 | No | ||
61 | PRKAG3 | 8047 | 0.606 | -0.1679 | No | ||
62 | MAPK12 | 8571 | 0.491 | -0.1952 | No | ||
63 | MAP3K4 | 8643 | 0.476 | -0.1980 | No | ||
64 | AKT1 | 8696 | 0.467 | -0.1998 | No | ||
65 | TSSK1A | 8708 | 0.464 | -0.1993 | No | ||
66 | ERN1 | 8829 | 0.440 | -0.2049 | No | ||
67 | WNK3 | 8969 | 0.407 | -0.2115 | No | ||
68 | RPS6KB2 | 9369 | 0.322 | -0.2324 | No | ||
69 | CIT | 9818 | 0.218 | -0.2562 | No | ||
70 | PRKCE | 10026 | 0.168 | -0.2671 | No | ||
71 | PRKCI | 10153 | 0.137 | -0.2736 | No | ||
72 | RIPK1 | 10351 | 0.086 | -0.2841 | No | ||
73 | STK38L | 10445 | 0.059 | -0.2890 | No | ||
74 | HUNK | 10449 | 0.057 | -0.2891 | No | ||
75 | EIF2AK4 | 10507 | 0.042 | -0.2921 | No | ||
76 | IRAK2 | 10553 | 0.028 | -0.2944 | No | ||
77 | STK38 | 10703 | -0.013 | -0.3025 | No | ||
78 | PLK3 | 10975 | -0.088 | -0.3170 | No | ||
79 | PRKCH | 11098 | -0.114 | -0.3234 | No | ||
80 | MAP3K2 | 11802 | -0.325 | -0.3608 | No | ||
81 | MAPK7 | 12338 | -0.478 | -0.3887 | No | ||
82 | CDC42BPA | 12345 | -0.481 | -0.3880 | No | ||
83 | SGK2 | 12404 | -0.498 | -0.3900 | No | ||
84 | RPS6KA5 | 12623 | -0.567 | -0.4006 | No | ||
85 | AKT2 | 12644 | -0.571 | -0.4004 | No | ||
86 | WNK4 | 12815 | -0.633 | -0.4082 | No | ||
87 | ROCK2 | 13447 | -0.872 | -0.4405 | No | ||
88 | MYLK | 13471 | -0.882 | -0.4398 | No | ||
89 | UHMK1 | 13487 | -0.888 | -0.4387 | No | ||
90 | MAP3K5 | 13604 | -0.929 | -0.4429 | No | ||
91 | GTF2H1 | 13865 | -1.036 | -0.4548 | No | ||
92 | MAP3K7 | 13920 | -1.056 | -0.4554 | No | ||
93 | MAPK4 | 13993 | -1.086 | -0.4569 | No | ||
94 | PLK4 | 14014 | -1.094 | -0.4556 | No | ||
95 | PHKA1 | 14165 | -1.172 | -0.4611 | No | ||
96 | PRKD1 | 14257 | -1.214 | -0.4634 | No | ||
97 | STK11 | 14570 | -1.358 | -0.4773 | No | ||
98 | CSNK2A1 | 14622 | -1.386 | -0.4770 | No | ||
99 | CSNK1A1 | 14797 | -1.485 | -0.4832 | No | ||
100 | NEK6 | 14810 | -1.490 | -0.4805 | No | ||
101 | PINK1 | 14968 | -1.585 | -0.4856 | No | ||
102 | PAK1 | 15056 | -1.632 | -0.4867 | No | ||
103 | MKNK1 | 15297 | -1.800 | -0.4957 | No | ||
104 | ATM | 15302 | -1.803 | -0.4920 | No | ||
105 | CDK3 | 15388 | -1.862 | -0.4925 | No | ||
106 | NEK4 | 15406 | -1.876 | -0.4893 | No | ||
107 | MAP3K11 | 15569 | -2.001 | -0.4936 | No | ||
108 | LIMK2 | 15843 | -2.225 | -0.5035 | Yes | ||
109 | CHEK2 | 15869 | -2.249 | -0.4999 | Yes | ||
110 | LATS2 | 15892 | -2.271 | -0.4961 | Yes | ||
111 | CSNK2A2 | 15927 | -2.307 | -0.4929 | Yes | ||
112 | ROCK1 | 15973 | -2.350 | -0.4902 | Yes | ||
113 | ACVR2B | 15985 | -2.360 | -0.4856 | Yes | ||
114 | CDKL1 | 16003 | -2.377 | -0.4812 | Yes | ||
115 | HIPK3 | 16023 | -2.407 | -0.4770 | Yes | ||
116 | TLK1 | 16048 | -2.434 | -0.4729 | Yes | ||
117 | CHUK | 16242 | -2.624 | -0.4776 | Yes | ||
118 | CPNE3 | 16377 | -2.765 | -0.4788 | Yes | ||
119 | VRK2 | 16392 | -2.787 | -0.4734 | Yes | ||
120 | MINK1 | 16411 | -2.804 | -0.4682 | Yes | ||
121 | CSNK1G2 | 16480 | -2.893 | -0.4655 | Yes | ||
122 | EIF2AK1 | 16490 | -2.906 | -0.4596 | Yes | ||
123 | IKBKE | 16547 | -2.984 | -0.4561 | Yes | ||
124 | MAPK8 | 16556 | -2.993 | -0.4499 | Yes | ||
125 | MAP4K4 | 16584 | -3.033 | -0.4447 | Yes | ||
126 | STK16 | 16642 | -3.102 | -0.4409 | Yes | ||
127 | PAK2 | 16651 | -3.116 | -0.4345 | Yes | ||
128 | STK17B | 16656 | -3.124 | -0.4278 | Yes | ||
129 | CLK1 | 16675 | -3.155 | -0.4219 | Yes | ||
130 | MAPK14 | 16698 | -3.190 | -0.4160 | Yes | ||
131 | MAPK6 | 16804 | -3.352 | -0.4143 | Yes | ||
132 | SRPK2 | 16818 | -3.380 | -0.4076 | Yes | ||
133 | PIM2 | 16854 | -3.440 | -0.4019 | Yes | ||
134 | TGFBR1 | 16864 | -3.455 | -0.3948 | Yes | ||
135 | PRKCB1 | 16871 | -3.459 | -0.3875 | Yes | ||
136 | PBK | 16879 | -3.468 | -0.3802 | Yes | ||
137 | NLK | 16994 | -3.635 | -0.3784 | Yes | ||
138 | CLK2 | 17042 | -3.709 | -0.3728 | Yes | ||
139 | MAPK1 | 17133 | -3.886 | -0.3691 | Yes | ||
140 | PHKA2 | 17205 | -4.012 | -0.3641 | Yes | ||
141 | PRKACB | 17236 | -4.056 | -0.3568 | Yes | ||
142 | STK10 | 17299 | -4.172 | -0.3510 | Yes | ||
143 | MAP3K8 | 17320 | -4.218 | -0.3428 | Yes | ||
144 | ULK1 | 17328 | -4.242 | -0.3338 | Yes | ||
145 | WNK1 | 17347 | -4.301 | -0.3253 | Yes | ||
146 | MAP4K3 | 17361 | -4.332 | -0.3165 | Yes | ||
147 | CDK5 | 17373 | -4.362 | -0.3075 | Yes | ||
148 | MAP3K3 | 17391 | -4.397 | -0.2987 | Yes | ||
149 | LMTK2 | 17453 | -4.546 | -0.2920 | Yes | ||
150 | PIM1 | 17464 | -4.569 | -0.2825 | Yes | ||
151 | PRKX | 17547 | -4.752 | -0.2765 | Yes | ||
152 | GSK3B | 17591 | -4.835 | -0.2681 | Yes | ||
153 | SNF1LK | 17611 | -4.895 | -0.2584 | Yes | ||
154 | PRKD3 | 17619 | -4.908 | -0.2480 | Yes | ||
155 | CDK2 | 17662 | -5.028 | -0.2392 | Yes | ||
156 | SRPK1 | 17690 | -5.093 | -0.2294 | Yes | ||
157 | EIF2AK3 | 17727 | -5.203 | -0.2199 | Yes | ||
158 | RIPK2 | 17775 | -5.360 | -0.2106 | Yes | ||
159 | STK4 | 17839 | -5.527 | -0.2019 | Yes | ||
160 | MAP3K12 | 17894 | -5.720 | -0.1922 | Yes | ||
161 | MAPK9 | 17946 | -5.900 | -0.1820 | Yes | ||
162 | TLK2 | 17991 | -6.101 | -0.1709 | Yes | ||
163 | SNF1LK2 | 18055 | -6.355 | -0.1603 | Yes | ||
164 | MAPK11 | 18122 | -6.671 | -0.1492 | Yes | ||
165 | BRDT | 18225 | -7.247 | -0.1388 | Yes | ||
166 | MAP4K2 | 18233 | -7.297 | -0.1231 | Yes | ||
167 | BRD2 | 18246 | -7.409 | -0.1074 | Yes | ||
168 | MARK2 | 18257 | -7.575 | -0.0913 | Yes | ||
169 | TGFBR2 | 18294 | -7.848 | -0.0759 | Yes | ||
170 | DYRK1A | 18309 | -8.008 | -0.0591 | Yes | ||
171 | PDPK1 | 18310 | -8.013 | -0.0414 | Yes | ||
172 | CSNK1E | 18325 | -8.146 | -0.0242 | Yes | ||
173 | SGK3 | 18420 | -9.034 | -0.0094 | Yes | ||
174 | SNRK | 18425 | -9.074 | 0.0104 | Yes |