Details for gene set PROTEIN_KINASE

Table: GSEA Results Summary

Dataset	set03_truncNotch_versus_normalThy
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	PROTEIN_KINASE_ACTIVITY
Enrichment Score (ES)	-0.47333348
Normalized Enrichment Score (NES)	-1.8237432
Nominal p-value	0.0
FDR q-value	1.0
FWER p-Value	0.887

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MAPKAPK2	58	8.591	0.0106	No
2	RIPK4	64	8.461	0.0238	No
3	RPS6KA1	310	5.834	0.0198	No
4	EPHB2	499	5.015	0.0176	No
5	CDC42BPB	685	4.386	0.0145	No
6	CSNK1D	740	4.252	0.0184	No
7	CDK10	850	3.988	0.0188	No
8	MAP3K7IP1	1199	3.378	0.0053	No
9	PHKG2	1219	3.346	0.0096	No
10	LTK	1302	3.218	0.0103	No
11	LIMK1	1307	3.210	0.0152	No
12	PDGFRB	1359	3.143	0.0174	No
13	TYRO3	1415	3.079	0.0193	No
14	BCKDK	1427	3.058	0.0236	No
15	STK19	1446	3.038	0.0275	No
16	PRKAG1	1456	3.028	0.0319	No
17	MAP4K5	1691	2.784	0.0236	No
18	CSF1R	1980	2.508	0.0119	No
19	MKNK2	2003	2.493	0.0147	No
20	EFNA3	2006	2.490	0.0185	No
21	TYK2	2072	2.454	0.0189	No
22	RYK	2110	2.421	0.0208	No
23	MARK1	2149	2.396	0.0225	No
24	EFNA4	2354	2.265	0.0151	No
25	MAP3K10	2364	2.261	0.0182	No
26	MERTK	2398	2.241	0.0200	No
27	DAPK3	2400	2.236	0.0235	No
28	PTK7	2457	2.207	0.0240	No
29	NEK2	2537	2.158	0.0231	No
30	IRAK3	2660	2.098	0.0198	No
31	CDK9	2765	2.038	0.0174	No
32	BRSK2	2816	2.011	0.0179	No
33	TESK1	2912	1.962	0.0159	No
34	TESK2	3031	1.914	0.0125	No
35	FGFR1	3163	1.855	0.0083	No
36	RPS6KC1	3171	1.852	0.0109	No
37	CRIM1	3206	1.836	0.0120	No
38	ACVR1B	3237	1.825	0.0133	No
39	NRP2	3347	1.778	0.0102	No
40	BCR	3474	1.735	0.0061	No
41	ROR1	3502	1.724	0.0074	No
42	IRAK1	3536	1.715	0.0083	No
43	ERBB2	3597	1.691	0.0078	No
44	TSSK6	3751	1.643	0.0021	No
45	RPS6KA2	3882	1.601	-0.0025	No
46	DDR1	3907	1.593	-0.0012	No
47	TTN	3997	1.568	-0.0036	No
48	DDR2	4024	1.560	-0.0025	No
49	CSNK2B	4093	1.540	-0.0037	No
50	TSSK3	4206	1.505	-0.0074	No
51	FLT4	4274	1.488	-0.0087	No
52	EPGN	4333	1.469	-0.0095	No
53	MAP2K7	4447	1.438	-0.0134	No
54	TSSK2	4589	1.406	-0.0188	No
55	NEK11	4620	1.396	-0.0182	No
56	MAP4K1	4652	1.388	-0.0177	No
57	MARK4	4735	1.368	-0.0199	No
58	ILK	4833	1.341	-0.0231	No
59	MAP3K9	4907	1.321	-0.0249	No
60	EGFR	4962	1.307	-0.0258	No
61	CDK7	5000	1.297	-0.0257	No
62	LYN	5368	1.203	-0.0438	No
63	PLK1	5426	1.189	-0.0450	No
64	MAST1	5471	1.173	-0.0455	No
65	PDGFRA	5642	1.135	-0.0530	No
66	EXOSC10	5695	1.122	-0.0540	No
67	PRKCZ	5893	1.076	-0.0630	No
68	FLT1	5927	1.069	-0.0631	No
69	ACVRL1	6015	1.049	-0.0661	No
70	RPS6KA3	6045	1.042	-0.0661	No
71	VRK1	6171	1.016	-0.0712	No
72	MAP3K6	6399	0.965	-0.0821	No
73	MUSK	6427	0.957	-0.0820	No
74	MAPK13	6583	0.919	-0.0890	No
75	TXK	6618	0.911	-0.0894	No
76	ERN2	6686	0.893	-0.0916	No
77	EIF2AK2	6696	0.891	-0.0907	No
78	MAPK10	6822	0.864	-0.0961	No
79	CCL2	6846	0.859	-0.0960	No
80	TAOK2	6927	0.840	-0.0990	No
81	ACVR2A	6983	0.830	-0.1006	No
82	PDK3	7035	0.818	-0.1021	No
83	ACVR1C	7058	0.814	-0.1020	No
84	MST1R	7063	0.813	-0.1009	No
85	MAP3K13	7072	0.811	-0.1001	No
86	CCL4	7140	0.792	-0.1024	No
87	PDK4	7179	0.786	-0.1033	No
88	STK3	7288	0.764	-0.1079	No
89	ROR2	7357	0.751	-0.1104	No
90	TRIB1	7399	0.742	-0.1115	No
91	EPHA5	7427	0.736	-0.1118	No
92	RIPK3	7538	0.714	-0.1166	No
93	MAPKAPK5	7540	0.713	-0.1155	No
94	DAPK2	7590	0.703	-0.1171	No
95	TTK	7608	0.697	-0.1169	No
96	KDR	7831	0.653	-0.1279	No
97	ACVR1	7867	0.645	-0.1288	No
98	PRKAG3	8047	0.606	-0.1376	No
99	TEK	8418	0.528	-0.1569	No
100	MAPK12	8571	0.491	-0.1644	No
101	MAP3K4	8643	0.476	-0.1675	No
102	AKT1	8696	0.467	-0.1696	No
103	TSSK1A	8708	0.464	-0.1694	No
104	ERN1	8829	0.440	-0.1752	No
105	WNK3	8969	0.407	-0.1822	No
106	RPS6KB2	9369	0.322	-0.2034	No
107	PDGFRL	9457	0.300	-0.2076	No
108	FGFR4	9474	0.295	-0.2080	No
109	FLT3	9541	0.280	-0.2112	No
110	TIE1	9780	0.225	-0.2238	No
111	CIT	9818	0.218	-0.2254	No
112	PRKCE	10026	0.168	-0.2364	No
113	PTK6	10129	0.143	-0.2418	No
114	PRKCI	10153	0.137	-0.2428	No
115	RIPK1	10351	0.086	-0.2534	No
116	STK38L	10445	0.059	-0.2584	No
117	HUNK	10449	0.057	-0.2584	No
118	MAP2K3	10472	0.051	-0.2595	No
119	EIF2AK4	10507	0.042	-0.2613	No
120	IRAK2	10553	0.028	-0.2637	No
121	STK38	10703	-0.013	-0.2718	No
122	TWF1	10872	-0.058	-0.2809	No
123	PLK3	10975	-0.088	-0.2863	No
124	PRKCH	11098	-0.114	-0.2928	No
125	ERBB3	11643	-0.274	-0.3219	No
126	NTRK1	11678	-0.284	-0.3233	No
127	MAPKAPK3	11729	-0.299	-0.3256	No
128	MAP3K2	11802	-0.325	-0.3290	No
129	AXL	11869	-0.341	-0.3320	No
130	INSR	12170	-0.426	-0.3477	No
131	FRK	12329	-0.475	-0.3555	No
132	MAPK7	12338	-0.478	-0.3552	No
133	CDC42BPA	12345	-0.481	-0.3548	No
134	SGK2	12404	-0.498	-0.3571	No
135	ERBB4	12607	-0.563	-0.3672	No
136	RPS6KA5	12623	-0.567	-0.3671	No
137	AKT2	12644	-0.571	-0.3673	No
138	WNK4	12815	-0.633	-0.3755	No
139	EFNB3	12919	-0.666	-0.3801	No
140	KIT	12949	-0.677	-0.3806	No
141	MET	13033	-0.707	-0.3840	No
142	ROCK2	13447	-0.872	-0.4051	No
143	ALK	13463	-0.879	-0.4045	No
144	MYLK	13471	-0.882	-0.4035	No
145	UHMK1	13487	-0.888	-0.4028	No
146	MAP3K5	13604	-0.929	-0.4077	No
147	GTF2H1	13865	-1.036	-0.4202	No
148	MAP3K7	13920	-1.056	-0.4214	No
149	MAPK4	13993	-1.086	-0.4236	No
150	PLK4	14014	-1.094	-0.4230	No
151	PHKA1	14165	-1.172	-0.4293	No
152	PRKD1	14257	-1.214	-0.4323	No
153	TGFA	14403	-1.289	-0.4381	No
154	EPHB6	14511	-1.332	-0.4418	No
155	STK11	14570	-1.358	-0.4428	No
156	CSNK2A1	14622	-1.386	-0.4433	No
157	PXK	14653	-1.403	-0.4427	No
158	CSNK1A1	14797	-1.485	-0.4482	No
159	NEK6	14810	-1.490	-0.4464	No
160	PINK1	14968	-1.585	-0.4524	No
161	TNK2	15043	-1.626	-0.4539	No
162	PAK1	15056	-1.632	-0.4519	No
163	MKNK1	15297	-1.800	-0.4621	No
164	ATM	15302	-1.803	-0.4594	No
165	TRIB2	15346	-1.839	-0.4588	No
166	CDK3	15388	-1.862	-0.4581	No
167	NEK4	15406	-1.876	-0.4560	No
168	CAMKK2	15520	-1.957	-0.4591	No
169	MAP3K11	15569	-2.001	-0.4585	No
170	LIMK2	15843	-2.225	-0.4698	Yes
171	CHEK2	15869	-2.249	-0.4675	Yes
172	LATS2	15892	-2.271	-0.4651	Yes
173	CSNK2A2	15927	-2.307	-0.4633	Yes
174	ROCK1	15973	-2.350	-0.4620	Yes
175	ACVR2B	15985	-2.360	-0.4588	Yes
176	IGF1R	15993	-2.371	-0.4554	Yes
177	CDKL1	16003	-2.377	-0.4521	Yes
178	ALS2CR2	16014	-2.391	-0.4488	Yes
179	HIPK3	16023	-2.407	-0.4454	Yes
180	TLK1	16048	-2.434	-0.4428	Yes
181	MAP2K1	16076	-2.460	-0.4404	Yes
182	CHUK	16242	-2.624	-0.4451	Yes
183	CPNE3	16377	-2.765	-0.4480	Yes
184	TRIM27	16386	-2.781	-0.4440	Yes
185	VRK2	16392	-2.787	-0.4398	Yes
186	MINK1	16411	-2.804	-0.4363	Yes
187	CSNK1G2	16480	-2.893	-0.4354	Yes
188	EIF2AK1	16490	-2.906	-0.4313	Yes
189	IKBKE	16547	-2.984	-0.4295	Yes
190	MAPK8	16556	-2.993	-0.4252	Yes
191	MAP4K4	16584	-3.033	-0.4218	Yes
192	STK16	16642	-3.102	-0.4200	Yes
193	PAK2	16651	-3.116	-0.4154	Yes
194	STK17B	16656	-3.124	-0.4106	Yes
195	CLK1	16675	-3.155	-0.4066	Yes
196	MAPK14	16698	-3.190	-0.4027	Yes
197	PDK1	16718	-3.213	-0.3986	Yes
198	MAPK6	16804	-3.352	-0.3978	Yes
199	SRPK2	16818	-3.380	-0.3932	Yes
200	PIM2	16854	-3.440	-0.3896	Yes
201	TGFBR1	16864	-3.455	-0.3845	Yes
202	PRKCB1	16871	-3.459	-0.3793	Yes
203	PBK	16879	-3.468	-0.3742	Yes
204	COL4A3BP	16958	-3.584	-0.3727	Yes
205	NLK	16994	-3.635	-0.3688	Yes
206	CLK2	17042	-3.709	-0.3654	Yes
207	MAPK1	17133	-3.886	-0.3641	Yes
208	PHKA2	17205	-4.012	-0.3616	Yes
209	PRKACB	17236	-4.056	-0.3567	Yes
210	STK10	17299	-4.172	-0.3534	Yes
211	MAP3K8	17320	-4.218	-0.3478	Yes
212	ULK1	17328	-4.242	-0.3414	Yes
213	WNK1	17347	-4.301	-0.3355	Yes
214	MAP4K3	17361	-4.332	-0.3293	Yes
215	CDK5	17373	-4.362	-0.3229	Yes
216	MAP3K3	17391	-4.397	-0.3168	Yes
217	LMTK2	17453	-4.546	-0.3128	Yes
218	PIM1	17464	-4.569	-0.3061	Yes
219	PRKX	17547	-4.752	-0.3030	Yes
220	GSK3B	17591	-4.835	-0.2976	Yes
221	SNF1LK	17611	-4.895	-0.2908	Yes
222	PRKD3	17619	-4.908	-0.2833	Yes
223	CDK2	17662	-5.028	-0.2776	Yes
224	SRPK1	17690	-5.093	-0.2709	Yes
225	EIF2AK3	17727	-5.203	-0.2646	Yes
226	RIPK2	17775	-5.360	-0.2585	Yes
227	MAP2K6	17779	-5.369	-0.2501	Yes
228	STK4	17839	-5.527	-0.2445	Yes
229	MAP3K12	17894	-5.720	-0.2383	Yes
230	MAPK9	17946	-5.900	-0.2317	Yes
231	IGF2R	17977	-6.036	-0.2236	Yes
232	TLK2	17991	-6.101	-0.2146	Yes
233	SNF1LK2	18055	-6.355	-0.2079	Yes
234	MAPK11	18122	-6.671	-0.2008	Yes
235	PDK2	18205	-7.150	-0.1938	Yes
236	BRDT	18225	-7.247	-0.1833	Yes
237	MAP4K2	18233	-7.297	-0.1720	Yes
238	BRD2	18246	-7.409	-0.1608	Yes
239	MARK2	18257	-7.575	-0.1493	Yes
240	TGFBR2	18294	-7.848	-0.1387	Yes
241	PTK2B	18300	-7.881	-0.1264	Yes
242	DYRK1A	18309	-8.008	-0.1140	Yes
243	PDPK1	18310	-8.013	-0.1012	Yes
244	CSNK1E	18325	-8.146	-0.0889	Yes
245	CRKL	18345	-8.316	-0.0767	Yes
246	SGK3	18420	-9.034	-0.0663	Yes
247	SNRK	18425	-9.074	-0.0520	Yes
248	CDK5R1	18501	-10.631	-0.0391	Yes
249	ITK	18503	-10.655	-0.0221	Yes
250	TEC	18583	-17.660	0.0018	Yes