Dataset | set03_truncNotch_versus_normalThy |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_neg |
GeneSet | PHOSPHOTRANSFERASE_ACTIVITY__ALCOHOL_GROUP_AS_ACCEPTOR |
Enrichment Score (ES) | -0.45292005 |
Normalized Enrichment Score (NES) | -1.7784946 |
Nominal p-value | 0.0 |
FDR q-value | 0.533641 |
FWER p-Value | 0.97 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | PKM2 | 3 | 15.094 | 0.0192 | No | ||
2 | MAPKAPK2 | 58 | 8.591 | 0.0274 | No | ||
3 | RIPK4 | 64 | 8.461 | 0.0380 | No | ||
4 | PFKM | 243 | 6.212 | 0.0362 | No | ||
5 | PFKL | 274 | 6.060 | 0.0424 | No | ||
6 | RPS6KA1 | 310 | 5.834 | 0.0480 | No | ||
7 | GALK1 | 363 | 5.566 | 0.0523 | No | ||
8 | EPHB2 | 499 | 5.015 | 0.0514 | No | ||
9 | PIK3R2 | 532 | 4.858 | 0.0559 | No | ||
10 | CDC42BPB | 685 | 4.386 | 0.0532 | No | ||
11 | CSNK1D | 740 | 4.252 | 0.0558 | No | ||
12 | COASY | 760 | 4.183 | 0.0601 | No | ||
13 | MVK | 791 | 4.100 | 0.0637 | No | ||
14 | CDK10 | 850 | 3.988 | 0.0657 | No | ||
15 | KHK | 1083 | 3.546 | 0.0576 | No | ||
16 | MAP3K7IP1 | 1199 | 3.378 | 0.0557 | No | ||
17 | PHKG2 | 1219 | 3.346 | 0.0589 | No | ||
18 | LTK | 1302 | 3.218 | 0.0586 | No | ||
19 | LIMK1 | 1307 | 3.210 | 0.0625 | No | ||
20 | PNKP | 1312 | 3.206 | 0.0664 | No | ||
21 | PDGFRB | 1359 | 3.143 | 0.0680 | No | ||
22 | TYRO3 | 1415 | 3.079 | 0.0689 | No | ||
23 | BCKDK | 1427 | 3.058 | 0.0722 | No | ||
24 | STK19 | 1446 | 3.038 | 0.0752 | No | ||
25 | PRKAG1 | 1456 | 3.028 | 0.0786 | No | ||
26 | MAP4K5 | 1691 | 2.784 | 0.0694 | No | ||
27 | CSF1R | 1980 | 2.508 | 0.0569 | No | ||
28 | MKNK2 | 2003 | 2.493 | 0.0589 | No | ||
29 | EFNA3 | 2006 | 2.490 | 0.0620 | No | ||
30 | TYK2 | 2072 | 2.454 | 0.0616 | No | ||
31 | RYK | 2110 | 2.421 | 0.0627 | No | ||
32 | MARK1 | 2149 | 2.396 | 0.0637 | No | ||
33 | EFNA4 | 2354 | 2.265 | 0.0555 | No | ||
34 | MAP3K10 | 2364 | 2.261 | 0.0579 | No | ||
35 | MERTK | 2398 | 2.241 | 0.0590 | No | ||
36 | DAPK3 | 2400 | 2.236 | 0.0618 | No | ||
37 | ITPKA | 2433 | 2.220 | 0.0629 | No | ||
38 | HK2 | 2436 | 2.216 | 0.0657 | No | ||
39 | PTK7 | 2457 | 2.207 | 0.0674 | No | ||
40 | NEK2 | 2537 | 2.158 | 0.0659 | No | ||
41 | DGKZ | 2598 | 2.130 | 0.0653 | No | ||
42 | IRAK3 | 2660 | 2.098 | 0.0647 | No | ||
43 | CDK9 | 2765 | 2.038 | 0.0617 | No | ||
44 | BRSK2 | 2816 | 2.011 | 0.0615 | No | ||
45 | TESK1 | 2912 | 1.962 | 0.0589 | No | ||
46 | TESK2 | 3031 | 1.914 | 0.0549 | No | ||
47 | FGFR1 | 3163 | 1.855 | 0.0501 | No | ||
48 | RPS6KC1 | 3171 | 1.852 | 0.0521 | No | ||
49 | CRIM1 | 3206 | 1.836 | 0.0526 | No | ||
50 | GNE | 3207 | 1.836 | 0.0550 | No | ||
51 | ACVR1B | 3237 | 1.825 | 0.0558 | No | ||
52 | NRP2 | 3347 | 1.778 | 0.0521 | No | ||
53 | BCR | 3474 | 1.735 | 0.0475 | No | ||
54 | ROR1 | 3502 | 1.724 | 0.0482 | No | ||
55 | IRAK1 | 3536 | 1.715 | 0.0486 | No | ||
56 | ERBB2 | 3597 | 1.691 | 0.0475 | No | ||
57 | TSSK6 | 3751 | 1.643 | 0.0413 | No | ||
58 | RPS6KA2 | 3882 | 1.601 | 0.0362 | No | ||
59 | DDR1 | 3907 | 1.593 | 0.0370 | No | ||
60 | TTN | 3997 | 1.568 | 0.0341 | No | ||
61 | DDR2 | 4024 | 1.560 | 0.0347 | No | ||
62 | CSNK2B | 4093 | 1.540 | 0.0330 | No | ||
63 | TSSK3 | 4206 | 1.505 | 0.0288 | No | ||
64 | FLT4 | 4274 | 1.488 | 0.0271 | No | ||
65 | EPGN | 4333 | 1.469 | 0.0258 | No | ||
66 | PFKFB1 | 4340 | 1.468 | 0.0274 | No | ||
67 | MAP2K7 | 4447 | 1.438 | 0.0234 | No | ||
68 | TSSK2 | 4589 | 1.406 | 0.0175 | No | ||
69 | NEK11 | 4620 | 1.396 | 0.0177 | No | ||
70 | MAP4K1 | 4652 | 1.388 | 0.0178 | No | ||
71 | MARK4 | 4735 | 1.368 | 0.0151 | No | ||
72 | ILK | 4833 | 1.341 | 0.0115 | No | ||
73 | MAP3K9 | 4907 | 1.321 | 0.0092 | No | ||
74 | EGFR | 4962 | 1.307 | 0.0080 | No | ||
75 | CDK7 | 5000 | 1.297 | 0.0076 | No | ||
76 | LYN | 5368 | 1.203 | -0.0109 | No | ||
77 | PLK1 | 5426 | 1.189 | -0.0124 | No | ||
78 | MAST1 | 5471 | 1.173 | -0.0133 | No | ||
79 | PDGFRA | 5642 | 1.135 | -0.0211 | No | ||
80 | EXOSC10 | 5695 | 1.122 | -0.0225 | No | ||
81 | PFKP | 5815 | 1.092 | -0.0276 | No | ||
82 | PRKCZ | 5893 | 1.076 | -0.0304 | No | ||
83 | FLT1 | 5927 | 1.069 | -0.0309 | No | ||
84 | XYLB | 5966 | 1.059 | -0.0316 | No | ||
85 | ACVRL1 | 6015 | 1.049 | -0.0329 | No | ||
86 | RPS6KA3 | 6045 | 1.042 | -0.0331 | No | ||
87 | VRK1 | 6171 | 1.016 | -0.0386 | No | ||
88 | MAP3K6 | 6399 | 0.965 | -0.0498 | No | ||
89 | MUSK | 6427 | 0.957 | -0.0500 | No | ||
90 | MAPK13 | 6583 | 0.919 | -0.0573 | No | ||
91 | TXK | 6618 | 0.911 | -0.0580 | No | ||
92 | ERN2 | 6686 | 0.893 | -0.0605 | No | ||
93 | EIF2AK2 | 6696 | 0.891 | -0.0598 | No | ||
94 | MAPK10 | 6822 | 0.864 | -0.0655 | No | ||
95 | CCL2 | 6846 | 0.859 | -0.0657 | No | ||
96 | TAOK2 | 6927 | 0.840 | -0.0690 | No | ||
97 | ACVR2A | 6983 | 0.830 | -0.0709 | No | ||
98 | PDK3 | 7035 | 0.818 | -0.0726 | No | ||
99 | ACVR1C | 7058 | 0.814 | -0.0728 | No | ||
100 | MST1R | 7063 | 0.813 | -0.0719 | No | ||
101 | MAP3K13 | 7072 | 0.811 | -0.0713 | No | ||
102 | CCL4 | 7140 | 0.792 | -0.0740 | No | ||
103 | PDK4 | 7179 | 0.786 | -0.0750 | No | ||
104 | STK3 | 7288 | 0.764 | -0.0799 | No | ||
105 | ROR2 | 7357 | 0.751 | -0.0827 | No | ||
106 | TRIB1 | 7399 | 0.742 | -0.0840 | No | ||
107 | EPHA5 | 7427 | 0.736 | -0.0845 | No | ||
108 | RIPK3 | 7538 | 0.714 | -0.0896 | No | ||
109 | MAPKAPK5 | 7540 | 0.713 | -0.0887 | No | ||
110 | DAPK2 | 7590 | 0.703 | -0.0905 | No | ||
111 | TTK | 7608 | 0.697 | -0.0905 | No | ||
112 | KDR | 7831 | 0.653 | -0.1018 | No | ||
113 | ACVR1 | 7867 | 0.645 | -0.1029 | No | ||
114 | PRKAG3 | 8047 | 0.606 | -0.1119 | No | ||
115 | TEK | 8418 | 0.528 | -0.1314 | No | ||
116 | MAPK12 | 8571 | 0.491 | -0.1390 | No | ||
117 | MAP3K4 | 8643 | 0.476 | -0.1423 | No | ||
118 | AKT1 | 8696 | 0.467 | -0.1445 | No | ||
119 | TSSK1A | 8708 | 0.464 | -0.1445 | No | ||
120 | ERN1 | 8829 | 0.440 | -0.1505 | No | ||
121 | WNK3 | 8969 | 0.407 | -0.1576 | No | ||
122 | PIK3R3 | 9143 | 0.368 | -0.1665 | No | ||
123 | PKLR | 9147 | 0.367 | -0.1662 | No | ||
124 | RPS6KB2 | 9369 | 0.322 | -0.1779 | No | ||
125 | PDGFRL | 9457 | 0.300 | -0.1822 | No | ||
126 | FGFR4 | 9474 | 0.295 | -0.1827 | No | ||
127 | HK1 | 9478 | 0.294 | -0.1825 | No | ||
128 | FLT3 | 9541 | 0.280 | -0.1855 | No | ||
129 | GCK | 9713 | 0.240 | -0.1946 | No | ||
130 | TIE1 | 9780 | 0.225 | -0.1979 | No | ||
131 | PIK3C2A | 9804 | 0.219 | -0.1988 | No | ||
132 | CIT | 9818 | 0.218 | -0.1993 | No | ||
133 | PRKCE | 10026 | 0.168 | -0.2103 | No | ||
134 | PTK6 | 10129 | 0.143 | -0.2157 | No | ||
135 | PRKCI | 10153 | 0.137 | -0.2168 | No | ||
136 | RIPK1 | 10351 | 0.086 | -0.2274 | No | ||
137 | STK38L | 10445 | 0.059 | -0.2324 | No | ||
138 | HUNK | 10449 | 0.057 | -0.2325 | No | ||
139 | MAP2K3 | 10472 | 0.051 | -0.2337 | No | ||
140 | EIF2AK4 | 10507 | 0.042 | -0.2355 | No | ||
141 | IRAK2 | 10553 | 0.028 | -0.2379 | No | ||
142 | PDXK | 10665 | -0.005 | -0.2439 | No | ||
143 | STK38 | 10703 | -0.013 | -0.2459 | No | ||
144 | TWF1 | 10872 | -0.058 | -0.2550 | No | ||
145 | PLK3 | 10975 | -0.088 | -0.2605 | No | ||
146 | PRKCH | 11098 | -0.114 | -0.2670 | No | ||
147 | ERBB3 | 11643 | -0.274 | -0.2963 | No | ||
148 | NTRK1 | 11678 | -0.284 | -0.2978 | No | ||
149 | MAPKAPK3 | 11729 | -0.299 | -0.3001 | No | ||
150 | MAP3K2 | 11802 | -0.325 | -0.3037 | No | ||
151 | AXL | 11869 | -0.341 | -0.3068 | No | ||
152 | INSR | 12170 | -0.426 | -0.3226 | No | ||
153 | FRK | 12329 | -0.475 | -0.3306 | No | ||
154 | MAPK7 | 12338 | -0.478 | -0.3305 | No | ||
155 | CDC42BPA | 12345 | -0.481 | -0.3302 | No | ||
156 | SGK2 | 12404 | -0.498 | -0.3327 | No | ||
157 | ERBB4 | 12607 | -0.563 | -0.3430 | No | ||
158 | RPS6KA5 | 12623 | -0.567 | -0.3431 | No | ||
159 | AKT2 | 12644 | -0.571 | -0.3434 | No | ||
160 | WNK4 | 12815 | -0.633 | -0.3519 | No | ||
161 | EFNB3 | 12919 | -0.666 | -0.3567 | No | ||
162 | KIT | 12949 | -0.677 | -0.3574 | No | ||
163 | MET | 13033 | -0.707 | -0.3610 | No | ||
164 | ROCK2 | 13447 | -0.872 | -0.3824 | No | ||
165 | ALK | 13463 | -0.879 | -0.3821 | No | ||
166 | MYLK | 13471 | -0.882 | -0.3813 | No | ||
167 | UHMK1 | 13487 | -0.888 | -0.3810 | No | ||
168 | MAP3K5 | 13604 | -0.929 | -0.3862 | No | ||
169 | GALK2 | 13705 | -0.969 | -0.3904 | No | ||
170 | GTF2H1 | 13865 | -1.036 | -0.3977 | No | ||
171 | MAP3K7 | 13920 | -1.056 | -0.3993 | No | ||
172 | MAPK4 | 13993 | -1.086 | -0.4018 | No | ||
173 | PLK4 | 14014 | -1.094 | -0.4015 | No | ||
174 | PHKA1 | 14165 | -1.172 | -0.4082 | No | ||
175 | N4BP2 | 14213 | -1.193 | -0.4092 | No | ||
176 | PRKD1 | 14257 | -1.214 | -0.4100 | No | ||
177 | TGFA | 14403 | -1.289 | -0.4163 | No | ||
178 | EPHB6 | 14511 | -1.332 | -0.4204 | No | ||
179 | STK11 | 14570 | -1.358 | -0.4218 | No | ||
180 | CHKA | 14586 | -1.365 | -0.4209 | No | ||
181 | CSNK2A1 | 14622 | -1.386 | -0.4210 | No | ||
182 | PXK | 14653 | -1.403 | -0.4208 | No | ||
183 | CSNK1A1 | 14797 | -1.485 | -0.4267 | No | ||
184 | NEK6 | 14810 | -1.490 | -0.4255 | No | ||
185 | PINK1 | 14968 | -1.585 | -0.4320 | No | ||
186 | PIP5K3 | 14988 | -1.596 | -0.4310 | No | ||
187 | TNK2 | 15043 | -1.626 | -0.4318 | No | ||
188 | PAK1 | 15056 | -1.632 | -0.4304 | No | ||
189 | MKNK1 | 15297 | -1.800 | -0.4412 | No | ||
190 | ATM | 15302 | -1.803 | -0.4391 | No | ||
191 | TRIB2 | 15346 | -1.839 | -0.4390 | No | ||
192 | CDK3 | 15388 | -1.862 | -0.4389 | No | ||
193 | NEK4 | 15406 | -1.876 | -0.4374 | No | ||
194 | CAMKK2 | 15520 | -1.957 | -0.4410 | No | ||
195 | MAP3K11 | 15569 | -2.001 | -0.4411 | No | ||
196 | PIK3CA | 15685 | -2.087 | -0.4447 | No | ||
197 | SPHK1 | 15837 | -2.220 | -0.4501 | Yes | ||
198 | LIMK2 | 15843 | -2.225 | -0.4475 | Yes | ||
199 | CHEK2 | 15869 | -2.249 | -0.4459 | Yes | ||
200 | LATS2 | 15892 | -2.271 | -0.4442 | Yes | ||
201 | CSNK2A2 | 15927 | -2.307 | -0.4431 | Yes | ||
202 | ROCK1 | 15973 | -2.350 | -0.4425 | Yes | ||
203 | ACVR2B | 15985 | -2.360 | -0.4401 | Yes | ||
204 | IGF1R | 15993 | -2.371 | -0.4374 | Yes | ||
205 | CDKL1 | 16003 | -2.377 | -0.4349 | Yes | ||
206 | ALS2CR2 | 16014 | -2.391 | -0.4324 | Yes | ||
207 | HIPK3 | 16023 | -2.407 | -0.4297 | Yes | ||
208 | TLK1 | 16048 | -2.434 | -0.4279 | Yes | ||
209 | MAP2K1 | 16076 | -2.460 | -0.4262 | Yes | ||
210 | PIK3CG | 16222 | -2.603 | -0.4307 | Yes | ||
211 | CHUK | 16242 | -2.624 | -0.4284 | Yes | ||
212 | CPNE3 | 16377 | -2.765 | -0.4322 | Yes | ||
213 | TRIM27 | 16386 | -2.781 | -0.4290 | Yes | ||
214 | VRK2 | 16392 | -2.787 | -0.4257 | Yes | ||
215 | MINK1 | 16411 | -2.804 | -0.4231 | Yes | ||
216 | CSNK1G2 | 16480 | -2.893 | -0.4231 | Yes | ||
217 | EIF2AK1 | 16490 | -2.906 | -0.4198 | Yes | ||
218 | IKBKE | 16547 | -2.984 | -0.4190 | Yes | ||
219 | MAPK8 | 16556 | -2.993 | -0.4156 | Yes | ||
220 | MAP4K4 | 16584 | -3.033 | -0.4132 | Yes | ||
221 | STK16 | 16642 | -3.102 | -0.4123 | Yes | ||
222 | PAK2 | 16651 | -3.116 | -0.4088 | Yes | ||
223 | STK17B | 16656 | -3.124 | -0.4050 | Yes | ||
224 | CLK1 | 16675 | -3.155 | -0.4019 | Yes | ||
225 | MAPK14 | 16698 | -3.190 | -0.3990 | Yes | ||
226 | PDK1 | 16718 | -3.213 | -0.3959 | Yes | ||
227 | MAPK6 | 16804 | -3.352 | -0.3962 | Yes | ||
228 | SRPK2 | 16818 | -3.380 | -0.3926 | Yes | ||
229 | PIM2 | 16854 | -3.440 | -0.3901 | Yes | ||
230 | TGFBR1 | 16864 | -3.455 | -0.3861 | Yes | ||
231 | PRKCB1 | 16871 | -3.459 | -0.3820 | Yes | ||
232 | PBK | 16879 | -3.468 | -0.3779 | Yes | ||
233 | COL4A3BP | 16958 | -3.584 | -0.3776 | Yes | ||
234 | NLK | 16994 | -3.635 | -0.3748 | Yes | ||
235 | CLK2 | 17042 | -3.709 | -0.3726 | Yes | ||
236 | DGKE | 17125 | -3.870 | -0.3721 | Yes | ||
237 | MAPK1 | 17133 | -3.886 | -0.3675 | Yes | ||
238 | PIK3CB | 17185 | -3.980 | -0.3651 | Yes | ||
239 | PHKA2 | 17205 | -4.012 | -0.3610 | Yes | ||
240 | PRKACB | 17236 | -4.056 | -0.3574 | Yes | ||
241 | STK10 | 17299 | -4.172 | -0.3554 | Yes | ||
242 | MAP3K8 | 17320 | -4.218 | -0.3511 | Yes | ||
243 | ULK1 | 17328 | -4.242 | -0.3460 | Yes | ||
244 | WNK1 | 17347 | -4.301 | -0.3415 | Yes | ||
245 | MAP4K3 | 17361 | -4.332 | -0.3366 | Yes | ||
246 | CDK5 | 17373 | -4.362 | -0.3316 | Yes | ||
247 | MAP3K3 | 17391 | -4.397 | -0.3269 | Yes | ||
248 | LMTK2 | 17453 | -4.546 | -0.3244 | Yes | ||
249 | PIM1 | 17464 | -4.569 | -0.3190 | Yes | ||
250 | PIK3C3 | 17533 | -4.731 | -0.3167 | Yes | ||
251 | PRKX | 17547 | -4.752 | -0.3113 | Yes | ||
252 | GSK3B | 17591 | -4.835 | -0.3074 | Yes | ||
253 | SNF1LK | 17611 | -4.895 | -0.3021 | Yes | ||
254 | PRKD3 | 17619 | -4.908 | -0.2962 | Yes | ||
255 | CDK2 | 17662 | -5.028 | -0.2920 | Yes | ||
256 | SRPK1 | 17690 | -5.093 | -0.2870 | Yes | ||
257 | EIF2AK3 | 17727 | -5.203 | -0.2822 | Yes | ||
258 | RIPK2 | 17775 | -5.360 | -0.2779 | Yes | ||
259 | MAP2K6 | 17779 | -5.369 | -0.2712 | Yes | ||
260 | STK4 | 17839 | -5.527 | -0.2673 | Yes | ||
261 | MAP3K12 | 17894 | -5.720 | -0.2629 | Yes | ||
262 | PI4K2A | 17938 | -5.879 | -0.2576 | Yes | ||
263 | MAPK9 | 17946 | -5.900 | -0.2504 | Yes | ||
264 | IGF2R | 17977 | -6.036 | -0.2443 | Yes | ||
265 | TLK2 | 17991 | -6.101 | -0.2372 | Yes | ||
266 | DGKQ | 17995 | -6.102 | -0.2295 | Yes | ||
267 | SNF1LK2 | 18055 | -6.355 | -0.2245 | Yes | ||
268 | ITPKB | 18061 | -6.397 | -0.2166 | Yes | ||
269 | MAPK11 | 18122 | -6.671 | -0.2113 | Yes | ||
270 | PDK2 | 18205 | -7.150 | -0.2066 | Yes | ||
271 | BRDT | 18225 | -7.247 | -0.1983 | Yes | ||
272 | MAP4K2 | 18233 | -7.297 | -0.1893 | Yes | ||
273 | BRD2 | 18246 | -7.409 | -0.1804 | Yes | ||
274 | MARK2 | 18257 | -7.575 | -0.1712 | Yes | ||
275 | TGFBR2 | 18294 | -7.848 | -0.1631 | Yes | ||
276 | PTK2B | 18300 | -7.881 | -0.1532 | Yes | ||
277 | DYRK1A | 18309 | -8.008 | -0.1434 | Yes | ||
278 | PDPK1 | 18310 | -8.013 | -0.1330 | Yes | ||
279 | CSNK1E | 18325 | -8.146 | -0.1233 | Yes | ||
280 | CRKL | 18345 | -8.316 | -0.1137 | Yes | ||
281 | PFKFB2 | 18406 | -8.849 | -0.1056 | Yes | ||
282 | SGK3 | 18420 | -9.034 | -0.0947 | Yes | ||
283 | SNRK | 18425 | -9.074 | -0.0832 | Yes | ||
284 | CDK5R1 | 18501 | -10.631 | -0.0736 | Yes | ||
285 | ITK | 18503 | -10.655 | -0.0600 | Yes | ||
286 | DGKA | 18512 | -10.953 | -0.0463 | Yes | ||
287 | TEC | 18583 | -17.660 | -0.0274 | Yes | ||
288 | DGKG | 18601 | -22.694 | 0.0008 | Yes |