Dataset | set03_truncNotch_versus_normalThy |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_pos |
GeneSet | MITOCHONDRION |
Enrichment Score (ES) | 0.4533315 |
Normalized Enrichment Score (NES) | 2.104553 |
Nominal p-value | 0.0 |
FDR q-value | 0.012256369 |
FWER p-Value | 0.011 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | SHMT2 | 20 | 10.771 | 0.0144 | Yes | ||
2 | BAX | 24 | 10.554 | 0.0295 | Yes | ||
3 | PHB2 | 32 | 10.037 | 0.0436 | Yes | ||
4 | TIMM50 | 34 | 9.946 | 0.0579 | Yes | ||
5 | ABCB6 | 49 | 9.174 | 0.0703 | Yes | ||
6 | MECR | 89 | 7.755 | 0.0794 | Yes | ||
7 | TIMM13 | 105 | 7.518 | 0.0894 | Yes | ||
8 | TXNRD2 | 109 | 7.482 | 0.1000 | Yes | ||
9 | MRPS10 | 116 | 7.370 | 0.1103 | Yes | ||
10 | GOT2 | 117 | 7.365 | 0.1209 | Yes | ||
11 | MRPS15 | 121 | 7.306 | 0.1313 | Yes | ||
12 | ACADS | 161 | 6.898 | 0.1391 | Yes | ||
13 | MTCH1 | 172 | 6.774 | 0.1483 | Yes | ||
14 | MRPS18A | 184 | 6.684 | 0.1574 | Yes | ||
15 | ATP5E | 223 | 6.409 | 0.1645 | Yes | ||
16 | ATP5G1 | 233 | 6.288 | 0.1731 | Yes | ||
17 | BCS1L | 239 | 6.248 | 0.1818 | Yes | ||
18 | TIMM10 | 253 | 6.177 | 0.1900 | Yes | ||
19 | MRPL55 | 256 | 6.167 | 0.1988 | Yes | ||
20 | ATP5G2 | 263 | 6.127 | 0.2073 | Yes | ||
21 | MRPL12 | 269 | 6.106 | 0.2158 | Yes | ||
22 | SOD2 | 275 | 6.057 | 0.2243 | Yes | ||
23 | TBRG4 | 294 | 5.916 | 0.2318 | Yes | ||
24 | CYC1 | 302 | 5.890 | 0.2399 | Yes | ||
25 | ETFB | 334 | 5.674 | 0.2464 | Yes | ||
26 | SOD1 | 352 | 5.616 | 0.2536 | Yes | ||
27 | NDUFV1 | 357 | 5.602 | 0.2615 | Yes | ||
28 | MRPS28 | 387 | 5.471 | 0.2678 | Yes | ||
29 | PCCB | 397 | 5.422 | 0.2751 | Yes | ||
30 | FDXR | 400 | 5.405 | 0.2828 | Yes | ||
31 | GSTZ1 | 474 | 5.089 | 0.2861 | Yes | ||
32 | NT5M | 480 | 5.082 | 0.2932 | Yes | ||
33 | HADH | 491 | 5.042 | 0.2999 | Yes | ||
34 | HTRA2 | 493 | 5.037 | 0.3071 | Yes | ||
35 | SLC25A1 | 507 | 4.950 | 0.3135 | Yes | ||
36 | SLC25A3 | 518 | 4.917 | 0.3201 | Yes | ||
37 | SDHB | 521 | 4.905 | 0.3270 | Yes | ||
38 | UQCRC1 | 541 | 4.840 | 0.3330 | Yes | ||
39 | FPGS | 598 | 4.623 | 0.3366 | Yes | ||
40 | PTGES2 | 617 | 4.567 | 0.3422 | Yes | ||
41 | TUFM | 621 | 4.558 | 0.3486 | Yes | ||
42 | MRPS11 | 625 | 4.545 | 0.3550 | Yes | ||
43 | NDUFA8 | 630 | 4.524 | 0.3613 | Yes | ||
44 | TOMM22 | 631 | 4.523 | 0.3678 | Yes | ||
45 | AIFM2 | 686 | 4.386 | 0.3712 | Yes | ||
46 | ATP5D | 750 | 4.224 | 0.3738 | Yes | ||
47 | LONP1 | 769 | 4.171 | 0.3789 | Yes | ||
48 | BAK1 | 795 | 4.093 | 0.3834 | Yes | ||
49 | ECSIT | 890 | 3.916 | 0.3839 | Yes | ||
50 | FIBP | 931 | 3.847 | 0.3873 | Yes | ||
51 | ACP6 | 968 | 3.771 | 0.3908 | Yes | ||
52 | LDHD | 1029 | 3.644 | 0.3927 | Yes | ||
53 | CLN3 | 1033 | 3.642 | 0.3978 | Yes | ||
54 | ABCF2 | 1034 | 3.636 | 0.4031 | Yes | ||
55 | PITRM1 | 1057 | 3.596 | 0.4070 | Yes | ||
56 | ECHS1 | 1064 | 3.577 | 0.4119 | Yes | ||
57 | MRPL10 | 1103 | 3.518 | 0.4149 | Yes | ||
58 | HSPE1 | 1215 | 3.355 | 0.4137 | Yes | ||
59 | AMT | 1283 | 3.249 | 0.4147 | Yes | ||
60 | NDUFS8 | 1292 | 3.237 | 0.4189 | Yes | ||
61 | NDUFS2 | 1334 | 3.172 | 0.4213 | Yes | ||
62 | COX4NB | 1351 | 3.157 | 0.4249 | Yes | ||
63 | BCKDK | 1427 | 3.058 | 0.4253 | Yes | ||
64 | BID | 1437 | 3.043 | 0.4291 | Yes | ||
65 | RAB11FIP5 | 1528 | 2.951 | 0.4285 | Yes | ||
66 | MRPS12 | 1719 | 2.761 | 0.4221 | Yes | ||
67 | TP53 | 1734 | 2.750 | 0.4253 | Yes | ||
68 | IMMT | 1858 | 2.628 | 0.4224 | Yes | ||
69 | HSPD1 | 1881 | 2.601 | 0.4249 | Yes | ||
70 | PPOX | 1902 | 2.586 | 0.4276 | Yes | ||
71 | GPX4 | 1915 | 2.573 | 0.4306 | Yes | ||
72 | MTHFD1 | 1948 | 2.537 | 0.4326 | Yes | ||
73 | NME4 | 2004 | 2.491 | 0.4331 | Yes | ||
74 | HSD17B10 | 2045 | 2.469 | 0.4345 | Yes | ||
75 | MRPS35 | 2074 | 2.453 | 0.4365 | Yes | ||
76 | HAX1 | 2111 | 2.420 | 0.4381 | Yes | ||
77 | SUPV3L1 | 2125 | 2.409 | 0.4408 | Yes | ||
78 | ATP5O | 2159 | 2.387 | 0.4425 | Yes | ||
79 | OPA1 | 2260 | 2.322 | 0.4404 | Yes | ||
80 | SARS2 | 2312 | 2.292 | 0.4409 | Yes | ||
81 | KARS | 2339 | 2.278 | 0.4427 | Yes | ||
82 | ACAT1 | 2437 | 2.216 | 0.4407 | Yes | ||
83 | NDUFA11 | 2468 | 2.199 | 0.4422 | Yes | ||
84 | PET112L | 2482 | 2.189 | 0.4446 | Yes | ||
85 | NDUFS7 | 2507 | 2.176 | 0.4465 | Yes | ||
86 | MRPS24 | 2582 | 2.139 | 0.4455 | Yes | ||
87 | COQ7 | 2632 | 2.107 | 0.4459 | Yes | ||
88 | ABCE1 | 2634 | 2.107 | 0.4489 | Yes | ||
89 | VDAC2 | 2650 | 2.103 | 0.4511 | Yes | ||
90 | COQ6 | 2665 | 2.095 | 0.4533 | Yes | ||
91 | MRPS16 | 2939 | 1.950 | 0.4413 | No | ||
92 | SDHC | 2989 | 1.930 | 0.4414 | No | ||
93 | GRPEL1 | 3027 | 1.915 | 0.4421 | No | ||
94 | MAOB | 3037 | 1.911 | 0.4444 | No | ||
95 | ALDH5A1 | 3132 | 1.864 | 0.4419 | No | ||
96 | SUCLG1 | 3182 | 1.848 | 0.4419 | No | ||
97 | MTRF1 | 3190 | 1.845 | 0.4442 | No | ||
98 | ATP5F1 | 3220 | 1.832 | 0.4453 | No | ||
99 | VDAC3 | 3382 | 1.766 | 0.4390 | No | ||
100 | PSEN1 | 3388 | 1.763 | 0.4413 | No | ||
101 | SDHD | 3430 | 1.750 | 0.4416 | No | ||
102 | DLD | 3514 | 1.721 | 0.4395 | No | ||
103 | SURF1 | 3552 | 1.706 | 0.4400 | No | ||
104 | DBT | 3628 | 1.680 | 0.4383 | No | ||
105 | PECI | 3753 | 1.643 | 0.4339 | No | ||
106 | MRPL23 | 3905 | 1.593 | 0.4280 | No | ||
107 | HINT2 | 4050 | 1.554 | 0.4224 | No | ||
108 | ABAT | 4051 | 1.554 | 0.4246 | No | ||
109 | PMPCA | 4061 | 1.551 | 0.4264 | No | ||
110 | COX6B2 | 4160 | 1.519 | 0.4232 | No | ||
111 | BCKDHA | 4208 | 1.505 | 0.4228 | No | ||
112 | GLYAT | 4234 | 1.498 | 0.4236 | No | ||
113 | ACADVL | 4323 | 1.474 | 0.4209 | No | ||
114 | PTRF | 4416 | 1.447 | 0.4180 | No | ||
115 | TIMM23 | 4432 | 1.443 | 0.4193 | No | ||
116 | NDUFS5 | 4780 | 1.353 | 0.4023 | No | ||
117 | TRNT1 | 4821 | 1.344 | 0.4021 | No | ||
118 | ATP5J | 4847 | 1.336 | 0.4026 | No | ||
119 | HCCS | 4874 | 1.329 | 0.4031 | No | ||
120 | NDUFS3 | 4902 | 1.322 | 0.4036 | No | ||
121 | CHCHD3 | 5300 | 1.221 | 0.3837 | No | ||
122 | ATP5A1 | 5317 | 1.218 | 0.3846 | No | ||
123 | HSD3B2 | 5322 | 1.215 | 0.3861 | No | ||
124 | SLC25A13 | 5394 | 1.199 | 0.3839 | No | ||
125 | TFB2M | 5405 | 1.195 | 0.3851 | No | ||
126 | COX15 | 5592 | 1.147 | 0.3766 | No | ||
127 | TIMM17A | 5622 | 1.140 | 0.3767 | No | ||
128 | CASQ1 | 5707 | 1.120 | 0.3737 | No | ||
129 | BDH2 | 5779 | 1.103 | 0.3715 | No | ||
130 | ACOT2 | 5946 | 1.062 | 0.3639 | No | ||
131 | HSD3B1 | 6119 | 1.026 | 0.3560 | No | ||
132 | NDUFA6 | 6132 | 1.024 | 0.3569 | No | ||
133 | CENTA2 | 6163 | 1.017 | 0.3567 | No | ||
134 | POLG2 | 6247 | 0.999 | 0.3536 | No | ||
135 | CPT1B | 6532 | 0.932 | 0.3395 | No | ||
136 | ACO2 | 6544 | 0.930 | 0.3402 | No | ||
137 | DECR1 | 6555 | 0.926 | 0.3410 | No | ||
138 | DMGDH | 6603 | 0.916 | 0.3397 | No | ||
139 | SLC25A4 | 6678 | 0.895 | 0.3370 | No | ||
140 | MIPEP | 6681 | 0.894 | 0.3382 | No | ||
141 | ALDH4A1 | 6880 | 0.851 | 0.3286 | No | ||
142 | IDH3B | 6915 | 0.844 | 0.3280 | No | ||
143 | SUCLA2 | 6992 | 0.828 | 0.3250 | No | ||
144 | MRPL40 | 7020 | 0.822 | 0.3247 | No | ||
145 | PDK3 | 7035 | 0.818 | 0.3252 | No | ||
146 | PDK4 | 7179 | 0.786 | 0.3185 | No | ||
147 | UCP3 | 7297 | 0.762 | 0.3132 | No | ||
148 | MFN2 | 7420 | 0.737 | 0.3076 | No | ||
149 | CKMT2 | 7470 | 0.726 | 0.3060 | No | ||
150 | ETFA | 7548 | 0.712 | 0.3028 | No | ||
151 | MRPS22 | 7572 | 0.706 | 0.3026 | No | ||
152 | NLRP5 | 7672 | 0.688 | 0.2982 | No | ||
153 | CYCS | 8120 | 0.587 | 0.2747 | No | ||
154 | MTX2 | 8143 | 0.582 | 0.2743 | No | ||
155 | MRPS18C | 8240 | 0.564 | 0.2699 | No | ||
156 | NIPSNAP1 | 8313 | 0.548 | 0.2667 | No | ||
157 | CPT1A | 8331 | 0.544 | 0.2666 | No | ||
158 | TIMM17B | 8332 | 0.544 | 0.2674 | No | ||
159 | ABCB7 | 8461 | 0.518 | 0.2611 | No | ||
160 | ESR2 | 8492 | 0.510 | 0.2602 | No | ||
161 | CS | 8493 | 0.510 | 0.2610 | No | ||
162 | TIMM9 | 8527 | 0.502 | 0.2599 | No | ||
163 | BCL2L10 | 8538 | 0.499 | 0.2601 | No | ||
164 | NR3C1 | 8735 | 0.461 | 0.2501 | No | ||
165 | BCKDHB | 8887 | 0.425 | 0.2424 | No | ||
166 | ATPIF1 | 8977 | 0.406 | 0.2382 | No | ||
167 | FXN | 8993 | 0.402 | 0.2379 | No | ||
168 | SARDH | 9214 | 0.353 | 0.2264 | No | ||
169 | MRPL52 | 9239 | 0.348 | 0.2256 | No | ||
170 | SLC25A27 | 9242 | 0.348 | 0.2260 | No | ||
171 | CRY1 | 9389 | 0.315 | 0.2185 | No | ||
172 | ACOT9 | 9431 | 0.305 | 0.2167 | No | ||
173 | IDH2 | 9527 | 0.283 | 0.2120 | No | ||
174 | BNIP3 | 9579 | 0.270 | 0.2096 | No | ||
175 | GATM | 9757 | 0.232 | 0.2003 | No | ||
176 | GLRX2 | 9811 | 0.218 | 0.1977 | No | ||
177 | ATP5G3 | 9871 | 0.206 | 0.1948 | No | ||
178 | NDUFA9 | 9896 | 0.199 | 0.1937 | No | ||
179 | ATP5C1 | 9944 | 0.189 | 0.1914 | No | ||
180 | MTHFD2 | 9988 | 0.178 | 0.1894 | No | ||
181 | MTIF2 | 10098 | 0.151 | 0.1836 | No | ||
182 | SLC22A4 | 10255 | 0.113 | 0.1753 | No | ||
183 | FDX1 | 10877 | -0.059 | 0.1415 | No | ||
184 | VDAC1 | 11042 | -0.101 | 0.1327 | No | ||
185 | OAT | 11141 | -0.128 | 0.1276 | No | ||
186 | UQCRB | 11202 | -0.146 | 0.1245 | No | ||
187 | COX8C | 11375 | -0.197 | 0.1154 | No | ||
188 | PHB | 11377 | -0.198 | 0.1156 | No | ||
189 | COX11 | 11419 | -0.209 | 0.1137 | No | ||
190 | MRPS36 | 11420 | -0.209 | 0.1140 | No | ||
191 | NFS1 | 11873 | -0.342 | 0.0899 | No | ||
192 | BBC3 | 11895 | -0.348 | 0.0892 | No | ||
193 | COX7A1 | 12096 | -0.406 | 0.0789 | No | ||
194 | MTERF | 12136 | -0.416 | 0.0774 | No | ||
195 | AFG3L2 | 12209 | -0.441 | 0.0741 | No | ||
196 | GHITM | 12298 | -0.467 | 0.0700 | No | ||
197 | SDHA | 12456 | -0.515 | 0.0621 | No | ||
198 | TOMM34 | 12568 | -0.551 | 0.0569 | No | ||
199 | BPHL | 12589 | -0.557 | 0.0566 | No | ||
200 | HMGCS2 | 12625 | -0.568 | 0.0555 | No | ||
201 | MUT | 12936 | -0.672 | 0.0396 | No | ||
202 | AMACR | 12966 | -0.683 | 0.0390 | No | ||
203 | PIN4 | 12988 | -0.692 | 0.0388 | No | ||
204 | HADHB | 13094 | -0.735 | 0.0342 | No | ||
205 | LRPPRC | 13268 | -0.800 | 0.0259 | No | ||
206 | TIMM8B | 13282 | -0.806 | 0.0263 | No | ||
207 | NDUFAB1 | 13477 | -0.884 | 0.0170 | No | ||
208 | SPG7 | 13523 | -0.898 | 0.0159 | No | ||
209 | UQCRH | 13569 | -0.915 | 0.0147 | No | ||
210 | SLC25A12 | 13682 | -0.958 | 0.0100 | No | ||
211 | AASS | 13750 | -0.990 | 0.0078 | No | ||
212 | BNIP3L | 13756 | -0.992 | 0.0089 | No | ||
213 | NDUFA1 | 13837 | -1.024 | 0.0061 | No | ||
214 | CASP8 | 13845 | -1.027 | 0.0072 | No | ||
215 | FIS1 | 13885 | -1.042 | 0.0065 | No | ||
216 | GBAS | 13897 | -1.046 | 0.0074 | No | ||
217 | GLUD1 | 13928 | -1.060 | 0.0073 | No | ||
218 | DHRS4 | 14057 | -1.121 | 0.0020 | No | ||
219 | NNT | 14083 | -1.130 | 0.0022 | No | ||
220 | SLC25A22 | 14088 | -1.133 | 0.0037 | No | ||
221 | ACN9 | 14185 | -1.180 | 0.0001 | No | ||
222 | ISCU | 14223 | -1.199 | -0.0002 | No | ||
223 | BZRAP1 | 14248 | -1.209 | 0.0003 | No | ||
224 | MRPL32 | 14480 | -1.320 | -0.0104 | No | ||
225 | DGUOK | 14496 | -1.326 | -0.0093 | No | ||
226 | NDUFA2 | 14505 | -1.328 | -0.0079 | No | ||
227 | POLRMT | 14596 | -1.369 | -0.0108 | No | ||
228 | PDHA1 | 14681 | -1.420 | -0.0133 | No | ||
229 | AIFM1 | 14698 | -1.432 | -0.0121 | No | ||
230 | GCDH | 14780 | -1.476 | -0.0144 | No | ||
231 | ARG2 | 14801 | -1.487 | -0.0134 | No | ||
232 | NDUFS1 | 14892 | -1.539 | -0.0161 | No | ||
233 | DNAJA3 | 14938 | -1.568 | -0.0162 | No | ||
234 | PINK1 | 14968 | -1.585 | -0.0155 | No | ||
235 | ATP5B | 14979 | -1.593 | -0.0138 | No | ||
236 | COQ4 | 14996 | -1.601 | -0.0124 | No | ||
237 | MPV17 | 15028 | -1.615 | -0.0117 | No | ||
238 | OGDH | 15045 | -1.626 | -0.0102 | No | ||
239 | CPOX | 15107 | -1.662 | -0.0112 | No | ||
240 | PMAIP1 | 15139 | -1.688 | -0.0104 | No | ||
241 | MSRB2 | 15190 | -1.734 | -0.0107 | No | ||
242 | CLPX | 15326 | -1.821 | -0.0154 | No | ||
243 | NDUFA4 | 15522 | -1.958 | -0.0232 | No | ||
244 | PRDX5 | 15523 | -1.959 | -0.0204 | No | ||
245 | MRPS21 | 15668 | -2.072 | -0.0252 | No | ||
246 | MRPL51 | 15782 | -2.171 | -0.0283 | No | ||
247 | SLC25A15 | 15948 | -2.321 | -0.0339 | No | ||
248 | RAF1 | 16017 | -2.394 | -0.0342 | No | ||
249 | MRPS31 | 16054 | -2.438 | -0.0326 | No | ||
250 | LETM1 | 16073 | -2.458 | -0.0301 | No | ||
251 | NDUFA13 | 16083 | -2.464 | -0.0270 | No | ||
252 | POLG | 16099 | -2.483 | -0.0242 | No | ||
253 | BCAT2 | 16151 | -2.536 | -0.0234 | No | ||
254 | SLC9A6 | 16422 | -2.817 | -0.0340 | No | ||
255 | ACADSB | 16503 | -2.926 | -0.0342 | No | ||
256 | PDK1 | 16718 | -3.213 | -0.0412 | No | ||
257 | TIMM44 | 16747 | -3.252 | -0.0381 | No | ||
258 | OXCT1 | 16749 | -3.258 | -0.0334 | No | ||
259 | RHOT1 | 16844 | -3.424 | -0.0336 | No | ||
260 | SLC25A14 | 16857 | -3.443 | -0.0293 | No | ||
261 | CKMT1A | 16874 | -3.464 | -0.0252 | No | ||
262 | DIABLO | 17102 | -3.815 | -0.0320 | No | ||
263 | ASAH2 | 17190 | -3.985 | -0.0310 | No | ||
264 | TFAM | 17291 | -4.153 | -0.0305 | No | ||
265 | SLC25A11 | 17353 | -4.314 | -0.0276 | No | ||
266 | RHOT2 | 17371 | -4.360 | -0.0223 | No | ||
267 | PTS | 17429 | -4.489 | -0.0189 | No | ||
268 | BCL2L1 | 17438 | -4.511 | -0.0128 | No | ||
269 | NDUFS4 | 17535 | -4.732 | -0.0112 | No | ||
270 | ACADM | 17820 | -5.462 | -0.0189 | No | ||
271 | ALAS2 | 17923 | -5.841 | -0.0160 | No | ||
272 | CASP7 | 18227 | -7.255 | -0.0221 | No | ||
273 | MYLC2PL | 18261 | -7.580 | -0.0129 | No | ||
274 | MCL1 | 18515 | -11.142 | -0.0107 | No | ||
275 | BCL2 | 18517 | -11.183 | 0.0054 | No |