Dataset | set03_absentNotch_versus_normalThy |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_neg |
GeneSet | PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY |
Enrichment Score (ES) | -0.47120014 |
Normalized Enrichment Score (NES) | -1.6956109 |
Nominal p-value | 0.0 |
FDR q-value | 0.58719474 |
FWER p-Value | 1.0 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | RIPK4 | 17 | 9.178 | 0.0269 | No | ||
2 | CSNK1D | 578 | 3.646 | 0.0075 | No | ||
3 | CDC42BPB | 755 | 3.314 | 0.0080 | No | ||
4 | MARK1 | 920 | 3.043 | 0.0083 | No | ||
5 | MAPK10 | 983 | 2.944 | 0.0139 | No | ||
6 | NEK4 | 1189 | 2.677 | 0.0109 | No | ||
7 | PRKCZ | 1203 | 2.659 | 0.0182 | No | ||
8 | RPS6KA1 | 1354 | 2.492 | 0.0176 | No | ||
9 | RPS6KA3 | 1863 | 2.086 | -0.0036 | No | ||
10 | TTK | 2008 | 2.006 | -0.0054 | No | ||
11 | MAPKAPK2 | 2095 | 1.954 | -0.0041 | No | ||
12 | GTF2H1 | 2175 | 1.914 | -0.0026 | No | ||
13 | IRAK3 | 2179 | 1.913 | 0.0030 | No | ||
14 | CHEK2 | 2226 | 1.886 | 0.0062 | No | ||
15 | EIF2AK2 | 2452 | 1.774 | -0.0006 | No | ||
16 | STK3 | 2512 | 1.750 | 0.0015 | No | ||
17 | RIPK1 | 2636 | 1.696 | -0.0000 | No | ||
18 | TESK1 | 3157 | 1.487 | -0.0237 | No | ||
19 | MAPK13 | 3249 | 1.457 | -0.0243 | No | ||
20 | MAP3K10 | 3326 | 1.427 | -0.0241 | No | ||
21 | TTN | 3638 | 1.316 | -0.0369 | No | ||
22 | PLK4 | 3662 | 1.309 | -0.0342 | No | ||
23 | IRAK1 | 3833 | 1.257 | -0.0396 | No | ||
24 | MAP3K13 | 3979 | 1.212 | -0.0438 | No | ||
25 | MAPK8 | 3997 | 1.205 | -0.0411 | No | ||
26 | MAP3K6 | 4064 | 1.188 | -0.0411 | No | ||
27 | MAP3K7 | 4229 | 1.146 | -0.0465 | No | ||
28 | NEK11 | 4330 | 1.119 | -0.0485 | No | ||
29 | CSNK1A1 | 4389 | 1.104 | -0.0483 | No | ||
30 | DAPK2 | 4400 | 1.100 | -0.0456 | No | ||
31 | RPS6KC1 | 4409 | 1.098 | -0.0427 | No | ||
32 | MAPK7 | 4474 | 1.083 | -0.0429 | No | ||
33 | ACVR1C | 4554 | 1.064 | -0.0439 | No | ||
34 | ROCK2 | 4595 | 1.057 | -0.0429 | No | ||
35 | ACVR1 | 5221 | 0.905 | -0.0740 | No | ||
36 | STK19 | 5319 | 0.880 | -0.0766 | No | ||
37 | CSNK2B | 5403 | 0.861 | -0.0785 | No | ||
38 | NEK2 | 5414 | 0.859 | -0.0765 | No | ||
39 | STK38L | 5605 | 0.820 | -0.0843 | No | ||
40 | CDK10 | 5617 | 0.817 | -0.0824 | No | ||
41 | TLK1 | 5802 | 0.779 | -0.0900 | No | ||
42 | VRK1 | 5806 | 0.779 | -0.0878 | No | ||
43 | PRKAG3 | 5888 | 0.761 | -0.0899 | No | ||
44 | TSSK2 | 5945 | 0.750 | -0.0907 | No | ||
45 | CDK9 | 6057 | 0.727 | -0.0945 | No | ||
46 | MAP3K9 | 6348 | 0.665 | -0.1082 | No | ||
47 | HUNK | 6350 | 0.664 | -0.1063 | No | ||
48 | PRKCE | 6499 | 0.633 | -0.1124 | No | ||
49 | DAPK3 | 6616 | 0.612 | -0.1168 | No | ||
50 | PRKAG1 | 6793 | 0.571 | -0.1246 | No | ||
51 | CHUK | 6859 | 0.560 | -0.1265 | No | ||
52 | AKT1 | 6874 | 0.557 | -0.1255 | No | ||
53 | CDK7 | 7199 | 0.492 | -0.1416 | No | ||
54 | TAOK2 | 7288 | 0.474 | -0.1450 | No | ||
55 | PAK2 | 7318 | 0.467 | -0.1451 | No | ||
56 | EXOSC10 | 7379 | 0.456 | -0.1470 | No | ||
57 | CDC42BPA | 7689 | 0.399 | -0.1625 | No | ||
58 | MAP3K4 | 7784 | 0.379 | -0.1665 | No | ||
59 | TSSK3 | 7824 | 0.371 | -0.1675 | No | ||
60 | MAPK6 | 8076 | 0.322 | -0.1801 | No | ||
61 | EIF2AK1 | 8189 | 0.302 | -0.1853 | No | ||
62 | BCKDK | 8301 | 0.283 | -0.1904 | No | ||
63 | RPS6KB2 | 8511 | 0.241 | -0.2010 | No | ||
64 | ACVRL1 | 8523 | 0.238 | -0.2009 | No | ||
65 | SRPK2 | 8729 | 0.199 | -0.2114 | No | ||
66 | ERN2 | 8890 | 0.174 | -0.2196 | No | ||
67 | CIT | 8970 | 0.159 | -0.2234 | No | ||
68 | ACVR2A | 9382 | 0.081 | -0.2454 | No | ||
69 | NEK6 | 9542 | 0.046 | -0.2539 | No | ||
70 | MAPKAPK5 | 9746 | -0.000 | -0.2649 | No | ||
71 | BRSK2 | 9790 | -0.011 | -0.2672 | No | ||
72 | TSSK6 | 10013 | -0.062 | -0.2791 | No | ||
73 | RPS6KA5 | 10181 | -0.097 | -0.2878 | No | ||
74 | RIPK3 | 10247 | -0.111 | -0.2910 | No | ||
75 | EIF2AK4 | 10279 | -0.121 | -0.2923 | No | ||
76 | TSSK1A | 10464 | -0.160 | -0.3018 | No | ||
77 | TESK2 | 10584 | -0.183 | -0.3077 | No | ||
78 | PRKACB | 10855 | -0.239 | -0.3216 | No | ||
79 | WNK4 | 11154 | -0.302 | -0.3369 | No | ||
80 | SGK2 | 11190 | -0.309 | -0.3378 | No | ||
81 | STK38 | 11295 | -0.330 | -0.3425 | No | ||
82 | PAK1 | 11346 | -0.340 | -0.3442 | No | ||
83 | MKNK2 | 11471 | -0.366 | -0.3498 | No | ||
84 | MYLK | 11553 | -0.385 | -0.3530 | No | ||
85 | PLK1 | 11717 | -0.422 | -0.3606 | No | ||
86 | ACVR2B | 11893 | -0.462 | -0.3687 | No | ||
87 | LIMK1 | 12451 | -0.593 | -0.3971 | No | ||
88 | WNK3 | 12462 | -0.595 | -0.3958 | No | ||
89 | ERN1 | 12523 | -0.609 | -0.3972 | No | ||
90 | MAPK4 | 12548 | -0.616 | -0.3966 | No | ||
91 | PHKG2 | 12974 | -0.721 | -0.4175 | No | ||
92 | BCR | 12982 | -0.724 | -0.4157 | No | ||
93 | CSNK2A2 | 13009 | -0.730 | -0.4149 | No | ||
94 | MAP3K5 | 13494 | -0.867 | -0.4385 | No | ||
95 | ACVR1B | 13573 | -0.893 | -0.4400 | No | ||
96 | TGFBR1 | 13591 | -0.902 | -0.4382 | No | ||
97 | RPS6KA2 | 13596 | -0.903 | -0.4357 | No | ||
98 | PRKCB1 | 13692 | -0.927 | -0.4381 | No | ||
99 | PHKA1 | 13712 | -0.936 | -0.4363 | No | ||
100 | ROCK1 | 13717 | -0.937 | -0.4336 | No | ||
101 | MAST1 | 13800 | -0.962 | -0.4352 | No | ||
102 | STK11 | 14028 | -1.040 | -0.4443 | No | ||
103 | STK16 | 14040 | -1.045 | -0.4418 | No | ||
104 | CSNK2A1 | 14044 | -1.046 | -0.4388 | No | ||
105 | PRKD1 | 14218 | -1.106 | -0.4448 | No | ||
106 | MAP3K2 | 14220 | -1.108 | -0.4415 | No | ||
107 | MAPK12 | 14274 | -1.127 | -0.4410 | No | ||
108 | IRAK2 | 14301 | -1.134 | -0.4389 | No | ||
109 | HIPK3 | 14507 | -1.208 | -0.4464 | No | ||
110 | MAPK14 | 14531 | -1.214 | -0.4440 | No | ||
111 | PRKCI | 15034 | -1.413 | -0.4669 | Yes | ||
112 | UHMK1 | 15035 | -1.414 | -0.4626 | Yes | ||
113 | MKNK1 | 15044 | -1.418 | -0.4588 | Yes | ||
114 | PBK | 15193 | -1.482 | -0.4623 | Yes | ||
115 | MAPK1 | 15209 | -1.490 | -0.4586 | Yes | ||
116 | VRK2 | 15212 | -1.492 | -0.4542 | Yes | ||
117 | MAP4K4 | 15416 | -1.601 | -0.4604 | Yes | ||
118 | CDK2 | 15515 | -1.650 | -0.4607 | Yes | ||
119 | CDK3 | 15570 | -1.680 | -0.4586 | Yes | ||
120 | MAP4K5 | 15706 | -1.757 | -0.4606 | Yes | ||
121 | CLK1 | 15833 | -1.834 | -0.4618 | Yes | ||
122 | STK4 | 15864 | -1.857 | -0.4578 | Yes | ||
123 | PLK3 | 15928 | -1.897 | -0.4555 | Yes | ||
124 | CDKL1 | 15959 | -1.912 | -0.4514 | Yes | ||
125 | NLK | 16010 | -1.942 | -0.4482 | Yes | ||
126 | LMTK2 | 16033 | -1.960 | -0.4435 | Yes | ||
127 | AKT2 | 16083 | -1.993 | -0.4401 | Yes | ||
128 | GSK3B | 16087 | -1.994 | -0.4342 | Yes | ||
129 | LATS2 | 16196 | -2.095 | -0.4337 | Yes | ||
130 | ATM | 16233 | -2.123 | -0.4293 | Yes | ||
131 | MARK4 | 16276 | -2.162 | -0.4250 | Yes | ||
132 | MAP4K1 | 16285 | -2.168 | -0.4189 | Yes | ||
133 | WNK1 | 16341 | -2.221 | -0.4151 | Yes | ||
134 | PRKX | 16376 | -2.248 | -0.4102 | Yes | ||
135 | STK17B | 16471 | -2.334 | -0.4082 | Yes | ||
136 | ILK | 16520 | -2.381 | -0.4036 | Yes | ||
137 | PRKD3 | 16666 | -2.529 | -0.4038 | Yes | ||
138 | SRPK1 | 16686 | -2.540 | -0.3972 | Yes | ||
139 | PRKCH | 16734 | -2.592 | -0.3919 | Yes | ||
140 | MAPK9 | 16893 | -2.804 | -0.3919 | Yes | ||
141 | MAP4K3 | 16972 | -2.892 | -0.3874 | Yes | ||
142 | CPNE3 | 17012 | -2.943 | -0.3806 | Yes | ||
143 | MINK1 | 17042 | -2.989 | -0.3732 | Yes | ||
144 | CSNK1G2 | 17052 | -2.996 | -0.3646 | Yes | ||
145 | LIMK2 | 17076 | -3.030 | -0.3567 | Yes | ||
146 | MAP3K11 | 17183 | -3.201 | -0.3527 | Yes | ||
147 | MAP3K8 | 17204 | -3.241 | -0.3440 | Yes | ||
148 | RIPK2 | 17205 | -3.242 | -0.3342 | Yes | ||
149 | TLK2 | 17220 | -3.268 | -0.3251 | Yes | ||
150 | PHKA2 | 17387 | -3.561 | -0.3233 | Yes | ||
151 | CLK2 | 17470 | -3.735 | -0.3164 | Yes | ||
152 | ULK1 | 17590 | -3.987 | -0.3108 | Yes | ||
153 | IKBKE | 17597 | -3.998 | -0.2990 | Yes | ||
154 | PINK1 | 17633 | -4.084 | -0.2886 | Yes | ||
155 | MAP3K12 | 17675 | -4.196 | -0.2781 | Yes | ||
156 | EIF2AK3 | 17721 | -4.310 | -0.2675 | Yes | ||
157 | CDK5 | 17726 | -4.322 | -0.2546 | Yes | ||
158 | SNF1LK | 17729 | -4.328 | -0.2417 | Yes | ||
159 | MAPK11 | 17757 | -4.401 | -0.2298 | Yes | ||
160 | PIM1 | 17761 | -4.415 | -0.2166 | Yes | ||
161 | PIM2 | 17790 | -4.508 | -0.2045 | Yes | ||
162 | STK10 | 17918 | -4.882 | -0.1966 | Yes | ||
163 | MAP3K3 | 18023 | -5.201 | -0.1865 | Yes | ||
164 | CSNK1E | 18048 | -5.309 | -0.1717 | Yes | ||
165 | PDPK1 | 18064 | -5.362 | -0.1563 | Yes | ||
166 | BRD2 | 18095 | -5.480 | -0.1414 | Yes | ||
167 | SNF1LK2 | 18208 | -6.071 | -0.1291 | Yes | ||
168 | BRDT | 18244 | -6.288 | -0.1119 | Yes | ||
169 | DYRK1A | 18283 | -6.537 | -0.0942 | Yes | ||
170 | MARK2 | 18285 | -6.557 | -0.0744 | Yes | ||
171 | SNRK | 18346 | -7.103 | -0.0562 | Yes | ||
172 | TGFBR2 | 18385 | -7.438 | -0.0357 | Yes | ||
173 | SGK3 | 18397 | -7.586 | -0.0134 | Yes | ||
174 | MAP4K2 | 18455 | -8.325 | 0.0087 | Yes |