Details for gene set HSA04810_REGULATION_OF_ACTIN

Table: GSEA Results Summary

Dataset	set03_absentNotch_versus_normalThy
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	HSA04810_REGULATION_OF_ACTIN_CYTOSKELETON
Enrichment Score (ES)	-0.51001185
Normalized Enrichment Score (NES)	-1.8394002
Nominal p-value	0.0
FDR q-value	0.14023507
FWER p-Value	0.939

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PTK2	64	7.089	0.0148	No
2	F2	323	4.441	0.0122	No
3	CFL1	458	3.955	0.0151	No
4	PIK3R3	654	3.483	0.0135	No
5	VCL	661	3.467	0.0221	No
6	CYFIP1	666	3.461	0.0308	No
7	CRK	816	3.207	0.0309	No
8	CD14	1049	2.871	0.0257	No
9	ITGB5	1077	2.832	0.0316	No
10	ITGB1	1126	2.766	0.0361	No
11	PDGFRA	1473	2.373	0.0234	No
12	PIK3R2	1505	2.342	0.0278	No
13	NCKAP1	1595	2.272	0.0288	No
14	ACTN3	1832	2.105	0.0214	No
15	PDGFRB	1899	2.068	0.0231	No
16	FGFR1	1948	2.038	0.0258	No
17	SSH1	2177	1.914	0.0183	No
18	PPP1CB	2216	1.891	0.0211	No
19	ARPC1B	2222	1.888	0.0257	No
20	MYH10	2317	1.841	0.0254	No
21	RDX	2392	1.804	0.0260	No
22	CDC42	2501	1.755	0.0247	No
23	CFL2	2542	1.735	0.0269	No
24	MYL9	2939	1.568	0.0095	No
25	FGFR3	2991	1.548	0.0107	No
26	PFN4	3038	1.530	0.0122	No
27	ITGA9	3143	1.495	0.0104	No
28	ARPC4	3276	1.445	0.0069	No
29	MAP2K2	3298	1.440	0.0095	No
30	FGFR2	3533	1.355	0.0003	No
31	APC	3540	1.354	0.0035	No
32	MYL7	3658	1.310	0.0005	No
33	EGF	3908	1.234	-0.0099	No
34	ARPC5L	3956	1.221	-0.0093	No
35	ARHGEF6	4012	1.202	-0.0091	No
36	KRAS	4401	1.100	-0.0274	No
37	ITGA4	4523	1.071	-0.0312	No
38	ROCK2	4595	1.057	-0.0323	No
39	FN1	4720	1.023	-0.0364	No
40	NRAS	4773	1.011	-0.0366	No
41	FGF9	4787	1.008	-0.0347	No
42	ARPC1A	4879	0.987	-0.0371	No
43	FGF5	5293	0.886	-0.0572	No
44	RAF1	5344	0.875	-0.0577	No
45	GSN	5604	0.820	-0.0696	No
46	DIAPH3	5676	0.804	-0.0714	No
47	RAC1	5946	0.749	-0.0841	No
48	FGF4	6036	0.730	-0.0870	No
49	ITGB6	6082	0.722	-0.0876	No
50	PIK3R1	6233	0.693	-0.0939	No
51	MRAS	6255	0.687	-0.0933	No
52	CHRM2	6267	0.685	-0.0922	No
53	ITGA11	6294	0.678	-0.0918	No
54	GNA12	6313	0.674	-0.0911	No
55	FGF10	6597	0.616	-0.1048	No
56	FGF21	6700	0.594	-0.1088	No
57	PAK3	6718	0.589	-0.1082	No
58	ITGA10	6911	0.548	-0.1172	No
59	FGF3	6916	0.547	-0.1160	No
60	RAC3	7120	0.508	-0.1257	No
61	FGF16	7157	0.500	-0.1264	No
62	ITGA7	7163	0.498	-0.1254	No
63	PAK2	7318	0.467	-0.1325	No
64	TMSB4X	7444	0.444	-0.1382	No
65	TIAM2	7483	0.437	-0.1391	No
66	BCAR1	7688	0.399	-0.1492	No
67	MYL2	7732	0.389	-0.1505	No
68	PFN3	7864	0.361	-0.1567	No
69	ARHGEF12	7879	0.359	-0.1565	No
70	FGF8	7901	0.354	-0.1567	No
71	MOS	8272	0.288	-0.1761	No
72	ITGA3	8321	0.280	-0.1779	No
73	RRAS	8432	0.258	-0.1832	No
74	FGF7	8802	0.187	-0.2028	No
75	FGD1	8840	0.182	-0.2043	No
76	WASF1	8842	0.182	-0.2039	No
77	HRAS	9039	0.147	-0.2141	No
78	GNG12	9118	0.131	-0.2180	No
79	ABI2	9177	0.120	-0.2209	No
80	FGF17	9220	0.113	-0.2229	No
81	PXN	9295	0.097	-0.2266	No
82	PIK3CB	9318	0.093	-0.2276	No
83	MAP2K1	9344	0.087	-0.2287	No
84	ITGAM	9474	0.061	-0.2355	No
85	ITGAV	9627	0.025	-0.2437	No
86	MYH14	9704	0.007	-0.2478	No
87	FGF23	9737	0.002	-0.2496	No
88	GNA13	10003	-0.059	-0.2638	No
89	ITGAX	10335	-0.133	-0.2814	No
90	SOS1	10560	-0.179	-0.2931	No
91	PIP5K3	10790	-0.223	-0.3049	No
92	BDKRB1	10941	-0.256	-0.3124	No
93	FGFR4	11138	-0.299	-0.3222	No
94	FGF14	11201	-0.310	-0.3248	No
95	PAK1	11346	-0.340	-0.3317	No
96	TIAM1	11381	-0.346	-0.3327	No
97	CHRM5	11546	-0.383	-0.3406	No
98	MYLK	11553	-0.385	-0.3399	No
99	FGF2	11646	-0.406	-0.3439	No
100	CHRM4	11669	-0.411	-0.3440	No
101	PAK7	11698	-0.418	-0.3445	No
102	ACTN2	12017	-0.488	-0.3605	No
103	CHRM1	12158	-0.520	-0.3667	No
104	FGF20	12238	-0.542	-0.3696	No
105	SOS2	12257	-0.546	-0.3692	No
106	LIMK1	12451	-0.593	-0.3781	No
107	ITGB7	12652	-0.640	-0.3873	No
108	FGF18	13126	-0.767	-0.4110	No
109	FGF11	13142	-0.773	-0.4098	No
110	BDKRB2	13192	-0.785	-0.4104	No
111	ARHGEF7	13668	-0.920	-0.4338	No
112	ARPC2	13696	-0.929	-0.4329	No
113	ROCK1	13717	-0.937	-0.4316	No
114	ITGA8	13787	-0.959	-0.4329	No
115	IQGAP1	13833	-0.974	-0.4328	No
116	MAPK3	13948	-1.009	-0.4364	No
117	EGFR	13992	-1.027	-0.4361	No
118	CHRM3	14043	-1.046	-0.4361	No
119	PFN1	14045	-1.047	-0.4335	No
120	SLC9A1	14111	-1.067	-0.4342	No
121	PIK3CA	14498	-1.205	-0.4521	No
122	FGF1	15032	-1.413	-0.4773	No
123	FGF22	15069	-1.430	-0.4756	No
124	PAK4	15098	-1.444	-0.4734	No
125	ITGA2B	15118	-1.450	-0.4707	No
126	MAPK1	15209	-1.490	-0.4718	No
127	APC2	15609	-1.703	-0.4890	No
128	VAV3	15745	-1.781	-0.4918	No
129	PDGFB	15770	-1.798	-0.4884	No
130	PIK3CG	16169	-2.073	-0.5047	Yes
131	PPP1R12A	16176	-2.078	-0.4997	Yes
132	ARPC5	16190	-2.087	-0.4950	Yes
133	FGF12	16218	-2.109	-0.4910	Yes
134	PPP1CC	16230	-2.120	-0.4862	Yes
135	ARAF	16268	-2.156	-0.4826	Yes
136	PIK3CD	16364	-2.240	-0.4820	Yes
137	FGD3	16407	-2.276	-0.4784	Yes
138	WASL	16479	-2.345	-0.4763	Yes
139	CSK	16538	-2.400	-0.4732	Yes
140	ITGB3	16731	-2.590	-0.4770	Yes
141	RRAS2	16913	-2.821	-0.4795	Yes
142	PPP1CA	16921	-2.831	-0.4726	Yes
143	WASF2	17028	-2.961	-0.4708	Yes
144	MSN	17060	-3.000	-0.4647	Yes
145	LIMK2	17076	-3.030	-0.4578	Yes
146	ARPC3	17144	-3.138	-0.4533	Yes
147	ITGA5	17153	-3.155	-0.4456	Yes
148	SSH3	17181	-3.198	-0.4389	Yes
149	RAC2	17312	-3.412	-0.4371	Yes
150	VAV2	17336	-3.460	-0.4295	Yes
151	ITGB2	17454	-3.701	-0.4263	Yes
152	BAIAP2	17613	-4.032	-0.4245	Yes
153	ITGAE	17733	-4.335	-0.4198	Yes
154	WAS	17765	-4.434	-0.4101	Yes
155	PIP5K1C	17856	-4.690	-0.4029	Yes
156	CRKL	17893	-4.821	-0.3924	Yes
157	FGF13	17897	-4.828	-0.3802	Yes
158	ACTN4	17899	-4.834	-0.3678	Yes
159	F2R	17921	-4.889	-0.3564	Yes
160	ITGAL	17935	-4.914	-0.3444	Yes
161	VAV1	17943	-4.944	-0.3321	Yes
162	ITGB4	18017	-5.184	-0.3227	Yes
163	PDGFA	18133	-5.648	-0.3144	Yes
164	PIK3R5	18141	-5.704	-0.3001	Yes
165	MYH9	18160	-5.806	-0.2862	Yes
166	MYLPF	18175	-5.849	-0.2719	Yes
167	RHOA	18189	-5.967	-0.2572	Yes
168	PFN2	18332	-6.976	-0.2470	Yes
169	SSH2	18334	-6.983	-0.2291	Yes
170	PIP5K1B	18388	-7.474	-0.2127	Yes
171	CYFIP2	18398	-7.597	-0.1937	Yes
172	MYLC2PL	18400	-7.606	-0.1742	Yes
173	ARHGEF1	18526	-10.050	-0.1551	Yes
174	SCIN	18596	-18.657	-0.1108	Yes
175	PIP5K1A	18602	-20.953	-0.0572	Yes
176	ITGA6	18607	-22.511	0.0005	Yes