Details for gene set AGEING_KIDNEY

Table: GSEA Results Summary

Dataset	set02_ATM_minus_versus_BT_ATM_minus
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	AGEING_KIDNEY_UP
Enrichment Score (ES)	-0.5056518
Normalized Enrichment Score (NES)	-2.394219
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PGM2L1	180	2.983	-0.0013	No
2	APBB1IP	306	2.603	-0.0010	No
3	CCND3	425	2.389	-0.0008	No
4	EVI2A	537	2.229	-0.0007	No
5	CUGBP2	538	2.228	0.0045	No
6	RAD54L	561	2.194	0.0086	No
7	NRP1	716	2.039	0.0063	No
8	PHCA	737	2.021	0.0101	No
9	SLC40A1	939	1.857	0.0052	No
10	VCAM1	984	1.831	0.0074	No
11	VWCE	1068	1.776	0.0078	No
12	AATF	1086	1.766	0.0111	No
13	CLIC1	1288	1.660	0.0057	No
14	CCDC45	1344	1.634	0.0070	No
15	PTPRC	1419	1.597	0.0073	No
16	DOCK2	1485	1.568	0.0080	No
17	GZMA	1534	1.548	0.0094	No
18	SLC18A2	1574	1.532	0.0112	No
19	IFITM1	1619	1.511	0.0127	No
20	ARHGEF6	1736	1.469	0.0108	No
21	PTPRE	1771	1.454	0.0127	No
22	CANX	1790	1.442	0.0152	No
23	CD47	1791	1.442	0.0186	No
24	RGS1	1848	1.415	0.0193	No
25	PIGR	1859	1.410	0.0222	No
26	ARHGAP15	2034	1.350	0.0173	No
27	EBF1	2045	1.346	0.0200	No
28	NT5E	2290	1.264	0.0117	No
29	ARHGAP10	2305	1.257	0.0140	No
30	GGTA1	2535	1.189	0.0062	No
31	COL3A1	2736	1.141	-0.0004	No
32	RNF166	3053	1.070	-0.0125	No
33	CDO1	3222	1.032	-0.0178	No
34	CD38	3410	0.988	-0.0242	No
35	SOCS3	3433	0.984	-0.0229	No
36	COL27A1	3469	0.976	-0.0222	No
37	NNMT	3562	0.956	-0.0242	No
38	GMFG	3710	0.927	-0.0288	No
39	COL1A1	4020	0.869	-0.0411	No
40	PRUNE	4090	0.857	-0.0422	No
41	GABRP	4199	0.839	-0.0453	No
42	RPS27L	4200	0.839	-0.0433	No
43	FER1L3	4261	0.829	-0.0441	No
44	PGLS	4292	0.823	-0.0436	No
45	USP31	4397	0.804	-0.0465	No
46	TNFRSF11B	4403	0.803	-0.0448	No
47	MMP7	4536	0.780	-0.0491	No
48	CCL5	4636	0.767	-0.0519	No
49	CRIP1	4676	0.760	-0.0519	No
50	MOXD1	4708	0.755	-0.0516	No
51	TUBA3	4974	0.712	-0.0622	No
52	GPR61	5028	0.704	-0.0630	No
53	PIK3CG	5276	0.667	-0.0728	No
54	PXDN	5289	0.666	-0.0718	No
55	GZMK	5341	0.657	-0.0726	No
56	COL15A1	5431	0.644	-0.0752	No
57	RBMS3	5501	0.634	-0.0769	No
58	RAB3GAP1	5554	0.627	-0.0779	No
59	RNF138	5644	0.615	-0.0805	No
60	LIX1	5695	0.608	-0.0814	No
61	GPR56	6279	0.514	-0.1071	No
62	SULF2	6323	0.509	-0.1079	No
63	CLDN3	6515	0.484	-0.1156	No
64	CLEC7A	6518	0.484	-0.1146	No
65	SCN5A	6651	0.466	-0.1196	No
66	C1S	6807	0.444	-0.1257	No
67	C1R	6837	0.440	-0.1260	No
68	SPON1	6847	0.438	-0.1254	No
69	CTHRC1	6893	0.433	-0.1265	No
70	FBN1	7224	0.392	-0.1408	No
71	LUM	7260	0.387	-0.1415	No
72	ANTXR2	7328	0.375	-0.1437	No
73	COL5A1	7329	0.375	-0.1429	No
74	MGAT1	7397	0.367	-0.1451	No
75	IRAK1	7424	0.365	-0.1455	No
76	VEGFC	7469	0.357	-0.1466	No
77	TSPAN1	7488	0.355	-0.1466	No
78	TNC	7514	0.351	-0.1470	No
79	DTX3L	7694	0.327	-0.1545	No
80	VARS	7750	0.320	-0.1563	No
81	NOV	7853	0.306	-0.1603	No
82	COL8A2	7895	0.301	-0.1615	No
83	LY75	8355	0.239	-0.1821	No
84	GPX1	8530	0.214	-0.1897	No
85	RARRES1	8577	0.207	-0.1913	No
86	GABRE	8593	0.204	-0.1915	No
87	STAB1	8669	0.194	-0.1945	No
88	PROM1	8726	0.187	-0.1967	No
89	RPL28	8794	0.176	-0.1994	No
90	ENAM	8926	0.158	-0.2050	No
91	CDH11	9049	0.140	-0.2104	No
92	RNASE6	9094	0.134	-0.2121	No
93	COMP	9175	0.124	-0.2155	No
94	SVEP1	9304	0.104	-0.2212	No
95	RAB34	9407	0.087	-0.2257	No
96	LOXL1	9507	0.074	-0.2301	No
97	SERPINE2	9569	0.065	-0.2327	No
98	AMBP	9930	0.006	-0.2494	No
99	FYB	9940	0.005	-0.2498	No
100	C1QC	9981	-0.001	-0.2516	No
101	ALPK2	10093	-0.018	-0.2567	No
102	FGG	10114	-0.022	-0.2576	No
103	FCER1G	10142	-0.025	-0.2588	No
104	STS	10165	-0.029	-0.2597	No
105	TYROBP	10381	-0.062	-0.2695	No
106	CASP1	10532	-0.083	-0.2762	No
107	CD97	10755	-0.116	-0.2862	No
108	TIMP1	10890	-0.139	-0.2921	No
109	FAS	11067	-0.164	-0.2999	No
110	CCDC23	11184	-0.178	-0.3048	No
111	CALU	11279	-0.191	-0.3087	No
112	TBXAS1	11377	-0.203	-0.3127	No
113	FDXR	11474	-0.214	-0.3166	No
114	DOCK11	11520	-0.220	-0.3182	No
115	SERPING1	11538	-0.222	-0.3185	No
116	APRT	11562	-0.224	-0.3190	No
117	CD14	11625	-0.231	-0.3213	No
118	NUAK1	11780	-0.248	-0.3279	No
119	TRIM47	11828	-0.255	-0.3294	No
120	TMED3	11996	-0.272	-0.3365	No
121	SSR4	12064	-0.279	-0.3390	No
122	RPL13A	12126	-0.286	-0.3411	No
123	RPL35A	12550	-0.339	-0.3599	No
124	PSMB9	12679	-0.353	-0.3650	No
125	TKT	12867	-0.374	-0.3727	No
126	RPL18	12995	-0.389	-0.3777	No
127	GRN	13105	-0.403	-0.3818	No
128	VASH1	13145	-0.408	-0.3826	No
129	MAP3K8	13234	-0.417	-0.3857	No
130	SPON2	13306	-0.425	-0.3880	No
131	PFN1	13354	-0.432	-0.3892	No
132	FN1	13360	-0.434	-0.3884	No
133	CCR1	13552	-0.456	-0.3961	No
134	SYTL2	13556	-0.456	-0.3952	No
135	ALOX5	13586	-0.459	-0.3955	No
136	PARVG	13657	-0.468	-0.3976	No
137	RUNX2	13659	-0.469	-0.3965	No
138	PRG1	13691	-0.472	-0.3969	No
139	SYMPK	13814	-0.488	-0.4014	No
140	CCM2	13964	-0.505	-0.4071	No
141	KLHDC5	13979	-0.507	-0.4065	No
142	VTCN1	14131	-0.523	-0.4123	No
143	CFB	14142	-0.524	-0.4115	No
144	MRAS	14204	-0.533	-0.4131	No
145	C1QB	14292	-0.544	-0.4158	No
146	NKG7	14349	-0.551	-0.4171	No
147	CORO1A	14491	-0.569	-0.4223	No
148	EML3	14600	-0.582	-0.4259	No
149	REEP4	14754	-0.601	-0.4316	No
150	TFPI	14757	-0.601	-0.4303	No
151	RAB31	14807	-0.607	-0.4311	No
152	MSR1	15091	-0.638	-0.4427	No
153	BHLHB3	15178	-0.650	-0.4452	No
154	COL14A1	15309	-0.666	-0.4496	No
155	DOK1	15319	-0.668	-0.4484	No
156	TREX1	15352	-0.672	-0.4484	No
157	IL17B	15461	-0.684	-0.4517	No
158	MYO1F	15552	-0.694	-0.4543	No
159	ANXA2	15569	-0.697	-0.4534	No
160	RAB8B	15628	-0.706	-0.4544	No
161	RPS25	15733	-0.720	-0.4575	No
162	ISLR	15751	-0.721	-0.4566	No
163	FAU	15816	-0.730	-0.4579	No
164	PSMB8	15830	-0.732	-0.4567	No
165	KRTCAP2	15846	-0.734	-0.4557	No
166	HTATIP2	15880	-0.739	-0.4555	No
167	ACTN1	15953	-0.750	-0.4571	No
168	PLOD3	15996	-0.757	-0.4572	No
169	EMP3	16063	-0.766	-0.4585	No
170	PTPN22	16138	-0.775	-0.4601	No
171	CLDN1	16184	-0.782	-0.4603	No
172	ANTXR1	16279	-0.795	-0.4628	No
173	ST8SIA4	16336	-0.802	-0.4635	No
174	TPBG	16360	-0.805	-0.4627	No
175	RBP1	16479	-0.821	-0.4662	No
176	HMHA1	16480	-0.821	-0.4643	No
177	PARP12	16491	-0.822	-0.4628	No
178	UBD	16505	-0.824	-0.4615	No
179	WFDC2	16702	-0.848	-0.4686	No
180	DOK3	16808	-0.863	-0.4714	No
181	RPL35	16904	-0.876	-0.4737	No
182	ECGF1	16932	-0.882	-0.4729	No
183	SLC12A9	17006	-0.892	-0.4742	No
184	SYNGR2	17074	-0.904	-0.4752	No
185	AEBP1	17129	-0.912	-0.4755	No
186	ASNS	17144	-0.915	-0.4740	No
187	RTN1	17217	-0.925	-0.4752	No
188	STOML1	17261	-0.931	-0.4750	No
189	NFKBIZ	17301	-0.938	-0.4746	No
190	BIRC3	17339	-0.944	-0.4741	No
191	CSPG2	17454	-0.963	-0.4771	No
192	HGF	17482	-0.969	-0.4761	No
193	DDX58	17778	-1.019	-0.4873	No
194	CHRNA3	17833	-1.027	-0.4874	No
195	FRS2	17861	-1.034	-0.4862	No
196	PPM1M	17884	-1.039	-0.4848	No
197	FHOD1	17925	-1.047	-0.4842	No
198	TGIF	17938	-1.050	-0.4823	No
199	DGKQ	18161	-1.085	-0.4900	No
200	LST1	18181	-1.089	-0.4883	No
201	SNCA	18286	-1.110	-0.4905	No
202	CXCL1	18358	-1.125	-0.4912	No
203	VSNL1	18433	-1.141	-0.4919	No
204	ARHGAP30	18621	-1.179	-0.4978	No
205	FNBP1	18676	-1.189	-0.4975	No
206	SLC1A3	18760	-1.208	-0.4985	No
207	CCL2	18809	-1.219	-0.4979	No
208	CNO	18880	-1.237	-0.4982	No
209	NFIX	18888	-1.239	-0.4956	No
210	RAC2	18896	-1.240	-0.4930	No
211	CSF1R	19015	-1.265	-0.4955	No
212	COL1A2	19064	-1.274	-0.4947	No
213	MYO5B	19195	-1.308	-0.4977	No
214	WDR46	19260	-1.327	-0.4975	No
215	CARHSP1	19320	-1.346	-0.4971	No
216	ADRA2A	19506	-1.396	-0.5024	Yes
217	IL10RA	19510	-1.397	-0.4992	Yes
218	DPP3	19553	-1.411	-0.4979	Yes
219	RAB33A	19588	-1.420	-0.4961	Yes
220	TMEM43	19589	-1.421	-0.4928	Yes
221	NR2F1	19622	-1.432	-0.4909	Yes
222	MALL	19645	-1.437	-0.4885	Yes
223	IFNAR1	19727	-1.471	-0.4888	Yes
224	PAM	19757	-1.478	-0.4867	Yes
225	HTR7	19785	-1.492	-0.4845	Yes
226	MFGE8	19837	-1.509	-0.4833	Yes
227	HCLS1	19929	-1.540	-0.4839	Yes
228	GGTLA1	19973	-1.555	-0.4822	Yes
229	CST6	20019	-1.577	-0.4806	Yes
230	LTB	20040	-1.586	-0.4778	Yes
231	ADAM8	20045	-1.588	-0.4742	Yes
232	SLC15A3	20046	-1.589	-0.4705	Yes
233	POU4F3	20078	-1.600	-0.4682	Yes
234	SLC6A6	20094	-1.607	-0.4651	Yes
235	DDEF1	20102	-1.609	-0.4617	Yes
236	IKBKB	20132	-1.623	-0.4592	Yes
237	ATHL1	20173	-1.640	-0.4572	Yes
238	TPM3	20175	-1.642	-0.4534	Yes
239	TRAFD1	20249	-1.674	-0.4528	Yes
240	HCST	20297	-1.698	-0.4510	Yes
241	SLAMF8	20358	-1.724	-0.4498	Yes
242	LCP2	20409	-1.744	-0.4480	Yes
243	TPM1	20488	-1.784	-0.4474	Yes
244	ARPC1B	20489	-1.784	-0.4432	Yes
245	CRELD2	20569	-1.832	-0.4426	Yes
246	P4HB	20590	-1.841	-0.4392	Yes
247	SETD7	20645	-1.873	-0.4373	Yes
248	PLEKHO1	20697	-1.906	-0.4352	Yes
249	PDIA4	20753	-1.937	-0.4332	Yes
250	DEGS1	20757	-1.942	-0.4287	Yes
251	MMP11	20759	-1.942	-0.4242	Yes
252	GNG2	20773	-1.950	-0.4203	Yes
253	CD69	20802	-1.970	-0.4169	Yes
254	FXYD5	20809	-1.973	-0.4126	Yes
255	CXCL14	20829	-1.984	-0.4088	Yes
256	FEZ2	20858	-2.002	-0.4054	Yes
257	IRAK2	20864	-2.006	-0.4009	Yes
258	CORO7	20907	-2.037	-0.3981	Yes
259	LTF	20956	-2.072	-0.3954	Yes
260	CD53	20958	-2.073	-0.3906	Yes
261	TNFAIP2	20965	-2.077	-0.3860	Yes
262	PARP14	20974	-2.087	-0.3815	Yes
263	CX3CR1	21036	-2.142	-0.3793	Yes
264	LIG3	21049	-2.151	-0.3748	Yes
265	LDLRAP1	21072	-2.163	-0.3707	Yes
266	IL10RB	21090	-2.188	-0.3664	Yes
267	AXL	21095	-2.192	-0.3614	Yes
268	ARHGAP1	21097	-2.192	-0.3563	Yes
269	GPNMB	21125	-2.215	-0.3524	Yes
270	ITPR3	21126	-2.217	-0.3472	Yes
271	MARCH1	21141	-2.228	-0.3426	Yes
272	ITM2C	21158	-2.247	-0.3381	Yes
273	MAN2B1	21184	-2.275	-0.3339	Yes
274	PIK3CD	21200	-2.293	-0.3292	Yes
275	RPN1	21204	-2.295	-0.3240	Yes
276	RASSF5	21270	-2.364	-0.3214	Yes
277	RPS6KA1	21310	-2.434	-0.3175	Yes
278	AYTL2	21312	-2.435	-0.3118	Yes
279	RGS19	21366	-2.510	-0.3084	Yes
280	ARHGDIB	21394	-2.566	-0.3036	Yes
281	ARHGAP25	21397	-2.571	-0.2977	Yes
282	PRICKLE1	21424	-2.616	-0.2928	Yes
283	RIN3	21437	-2.664	-0.2871	Yes
284	SAMD9L	21438	-2.669	-0.2808	Yes
285	SPARCL1	21448	-2.684	-0.2749	Yes
286	TCF3	21468	-2.726	-0.2694	Yes
287	TAPBP	21470	-2.730	-0.2630	Yes
288	LAPTM5	21514	-2.824	-0.2584	Yes
289	STAT6	21519	-2.830	-0.2520	Yes
290	ATP8B2	21523	-2.837	-0.2454	Yes
291	ABCC1	21592	-3.079	-0.2414	Yes
292	PTPN6	21597	-3.085	-0.2343	Yes
293	IRF8	21610	-3.117	-0.2275	Yes
294	APOE	21663	-3.318	-0.2222	Yes
295	CMTM3	21694	-3.502	-0.2153	Yes
296	TBC1D2B	21697	-3.512	-0.2072	Yes
297	CORO1C	21703	-3.548	-0.1991	Yes
298	STK10	21759	-3.915	-0.1925	Yes
299	CCND2	21792	-4.179	-0.1841	Yes
300	PSME2	21801	-4.260	-0.1745	Yes
301	C9ORF19	21807	-4.299	-0.1646	Yes
302	LASP1	21823	-4.444	-0.1549	Yes
303	TNFRSF25	21833	-4.603	-0.1445	Yes
304	CXCL16	21853	-4.800	-0.1341	Yes
305	RUNX3	21857	-4.865	-0.1229	Yes
306	ITGB2	21875	-5.244	-0.1114	Yes
307	ISGF3G	21881	-5.367	-0.0990	Yes
308	VIM	21890	-5.636	-0.0861	Yes
309	TESC	21895	-5.748	-0.0728	Yes
310	TGFBI	21900	-5.856	-0.0593	Yes
311	SCOTIN	21907	-6.138	-0.0452	Yes
312	LYSMD2	21911	-6.208	-0.0307	Yes
313	TMSB10	21927	-6.825	-0.0154	Yes
314	RGS10	21930	-6.943	0.0008	Yes