Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | set01_ATM_minus_versus_SCID |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY |
| Enrichment Score (ES) | -0.5007667 |
| Normalized Enrichment Score (NES) | -1.6497214 |
| Nominal p-value | 0.013574661 |
| FDR q-value | 0.3966533 |
| FWER p-Value | 0.995 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PIK3R1 | 880 | 4.360 | 0.0316 | No | ||
| 2 | CD3D | 882 | 4.358 | 0.1032 | No | ||
| 3 | CD28 | 1262 | 3.620 | 0.1455 | No | ||
| 4 | PAK1 | 2989 | 2.306 | 0.1047 | No | ||
| 5 | AKT1 | 4013 | 1.922 | 0.0896 | No | ||
| 6 | THEM4 | 5348 | 1.504 | 0.0535 | No | ||
| 7 | ICOSLG | 5485 | 1.464 | 0.0714 | No | ||
| 8 | MAP3K8 | 10208 | 0.325 | -0.1386 | No | ||
| 9 | CD86 | 10657 | 0.198 | -0.1558 | No | ||
| 10 | CD3G | 10964 | 0.100 | -0.1681 | No | ||
| 11 | CTLA4 | 11581 | -0.092 | -0.1947 | No | ||
| 12 | PDCD1 | 12557 | -0.381 | -0.2329 | No | ||
| 13 | BTLA | 14696 | -0.957 | -0.3147 | No | ||
| 14 | PDPK1 | 18359 | -2.062 | -0.4478 | No | ||
| 15 | CD80 | 18489 | -2.115 | -0.4189 | No | ||
| 16 | PTPN11 | 20285 | -3.088 | -0.4500 | Yes | ||
| 17 | PIK3CA | 20435 | -3.207 | -0.4040 | Yes | ||
| 18 | CD3E | 20464 | -3.238 | -0.3520 | Yes | ||
| 19 | VAV1 | 20481 | -3.253 | -0.2992 | Yes | ||
| 20 | FYN | 20519 | -3.289 | -0.2468 | Yes | ||
| 21 | GRAP2 | 20874 | -3.657 | -0.2028 | Yes | ||
| 22 | CD4 | 20985 | -3.795 | -0.1454 | Yes | ||
| 23 | CSK | 21565 | -5.125 | -0.0875 | Yes | ||
| 24 | LCK | 21782 | -6.376 | 0.0075 | Yes |
