Details for gene set PROTEIN_KINASE

Table: GSEA Results Summary

Dataset	set01_ATM_minus_versus_ATM_plus
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	PROTEIN_KINASE_CASCADE
Enrichment Score (ES)	-0.48824304
Normalized Enrichment Score (NES)	-2.134233
Nominal p-value	0.0
FDR q-value	0.014972797
FWER p-Value	0.016

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PRDX4	193	12.146	0.0008	No
2	DUSP9	291	10.801	0.0050	No
3	EEF1D	360	10.178	0.0100	No
4	TFG	503	9.004	0.0107	No
5	SLC35B2	689	8.017	0.0085	No
6	TNFSF10	893	7.236	0.0050	No
7	HMOX1	1027	6.810	0.0043	No
8	ZDHHC17	1140	6.457	0.0043	No
9	BST2	1274	6.105	0.0030	No
10	DUSP22	1346	5.915	0.0045	No
11	F2	1399	5.815	0.0067	No
12	BLK	1450	5.692	0.0090	No
13	ITGB1BP1	1608	5.394	0.0061	No
14	ECM1	1610	5.389	0.0103	No
15	CCL2	1663	5.299	0.0122	No
16	C5AR1	1709	5.233	0.0143	No
17	VAPA	1889	4.961	0.0100	No
18	MAPK8IP1	1902	4.938	0.0134	No
19	EDG2	2136	4.627	0.0064	No
20	SOD1	2146	4.618	0.0096	No
21	TGFA	2218	4.525	0.0100	No
22	ADRA2A	2222	4.513	0.0135	No
23	NRTN	2352	4.360	0.0110	No
24	ECT2	2560	4.143	0.0048	No
25	RHOC	2629	4.077	0.0049	No
26	PLK2	2644	4.057	0.0075	No
27	PROK2	2669	4.044	0.0096	No
28	EDG5	2714	4.003	0.0108	No
29	MAPKAPK2	2720	3.998	0.0138	No
30	GOLT1B	2794	3.957	0.0136	No
31	RPL17	2811	3.941	0.0160	No
32	FAF1	2945	3.834	0.0129	No
33	GPR89A	2971	3.820	0.0148	No
34	NUP62	3002	3.797	0.0165	No
35	IL31RA	3090	3.740	0.0155	No
36	SCG2	3146	3.697	0.0159	No
37	ADRA2C	3314	3.569	0.0110	No
38	FPR1	3376	3.516	0.0110	No
39	UBE2N	3412	3.489	0.0122	No
40	MAP3K6	3427	3.476	0.0143	No
41	MAST1	3467	3.451	0.0153	No
42	LATS2	3716	3.300	0.0065	No
43	NF2	3843	3.233	0.0033	No
44	PPP5C	4007	3.142	-0.0017	No
45	LGALS9	4022	3.131	0.0002	No
46	LGALS1	4293	2.998	-0.0099	No
47	NMI	4302	2.995	-0.0079	No
48	GHRL	4394	2.955	-0.0097	No
49	IRAK1BP1	4553	2.891	-0.0147	No
50	TNFRSF10B	4565	2.887	-0.0129	No
51	PTPLAD1	4805	2.791	-0.0217	No
52	LTBR	5104	2.685	-0.0333	No
53	ADAM9	5171	2.662	-0.0342	No
54	TMED4	5215	2.649	-0.0340	No
55	MAP3K9	5225	2.645	-0.0323	No
56	RPS6KA2	5248	2.639	-0.0312	No
57	RIPK1	5284	2.628	-0.0307	No
58	GSG2	5396	2.594	-0.0338	No
59	MAPK10	5422	2.586	-0.0329	No
60	GJA1	5432	2.583	-0.0312	No
61	ADORA2B	5461	2.570	-0.0305	No
62	FGFR3	5506	2.555	-0.0304	No
63	STK3	5627	2.519	-0.0340	No
64	ADRB3	6121	2.360	-0.0548	No
65	ADRA1A	6360	2.289	-0.0639	No
66	SOCS3	6520	2.246	-0.0695	No
67	IL12A	6521	2.246	-0.0677	No
68	IL20	6572	2.232	-0.0682	No
69	FGF2	6738	2.186	-0.0741	No
70	FGFR1	6855	2.152	-0.0777	No
71	MAP3K7	6975	2.124	-0.0815	No
72	FASLG	7259	2.047	-0.0929	No
73	SRPK1	7263	2.046	-0.0914	No
74	MAPK8IP2	7294	2.039	-0.0911	No
75	RPS6KA5	7337	2.027	-0.0914	No
76	STAMBP	7439	2.002	-0.0945	No
77	WNK2	7648	1.947	-0.1025	No
78	MDFI	7712	1.927	-0.1039	No
79	IRAK1	7859	1.892	-0.1091	No
80	MAP3K2	8636	1.709	-0.1435	No
81	DUSP8	8849	1.661	-0.1520	No
82	CD24	8918	1.644	-0.1538	No
83	TPD52L1	8920	1.643	-0.1525	No
84	NEK11	8953	1.637	-0.1527	No
85	WNK3	9218	1.571	-0.1636	No
86	SGK2	9392	1.532	-0.1704	No
87	MARK1	9398	1.530	-0.1694	No
88	TLR6	9407	1.528	-0.1685	No
89	MAP3K4	9437	1.520	-0.1686	No
90	WNK4	10123	1.354	-0.1991	No
91	LITAF	10262	1.320	-0.2044	No
92	EDA2R	10305	1.311	-0.2053	No
93	CHRNA7	10311	1.308	-0.2045	No
94	GNG3	10401	1.286	-0.2076	No
95	DAPK2	10688	1.217	-0.2198	No
96	CASP1	10705	1.212	-0.2196	No
97	MAPK13	10765	1.197	-0.2213	No
98	CARD10	11020	1.130	-0.2321	No
99	TRADD	11123	1.103	-0.2360	No
100	TRIM13	11134	1.100	-0.2355	No
101	NEK6	11571	0.974	-0.2549	No
102	GRM4	11922	0.864	-0.2703	No
103	DUSP10	11980	0.847	-0.2723	No
104	CASP8	12035	0.830	-0.2741	No
105	EGF	12295	0.756	-0.2854	No
106	TDGF1	12467	0.703	-0.2927	No
107	PLEKHG5	12625	0.650	-0.2995	No
108	NF1	12700	0.627	-0.3024	No
109	CD81	12940	0.537	-0.3130	No
110	RGS4	13168	0.450	-0.3231	No
111	ADRA1B	13187	0.441	-0.3235	No
112	SNF1LK	13371	0.369	-0.3317	No
113	AKAP11	13528	0.305	-0.3386	No
114	GADD45G	13718	0.218	-0.3472	No
115	AMBP	13939	0.112	-0.3572	No
116	MYD88	14281	-0.077	-0.3729	No
117	GPS2	14368	-0.134	-0.3767	No
118	CARTPT	14372	-0.135	-0.3768	No
119	ATP6AP2	14483	-0.212	-0.3817	No
120	PLCE1	14566	-0.256	-0.3853	No
121	HTR2B	14615	-0.277	-0.3872	No
122	DUSP4	14744	-0.376	-0.3928	No
123	SECTM1	14880	-0.466	-0.3987	No
124	ICK	14903	-0.477	-0.3993	No
125	REL	14913	-0.486	-0.3994	No
126	STK38L	14967	-0.508	-0.4014	No
127	TSPAN6	15046	-0.572	-0.4045	No
128	PIK3CB	15122	-0.630	-0.4075	No
129	SRC	15241	-0.705	-0.4124	No
130	CXXC5	15268	-0.719	-0.4130	No
131	TMEM101	15378	-0.792	-0.4174	No
132	CD40	15416	-0.823	-0.4184	No
133	CCR2	15486	-0.869	-0.4209	No
134	TRAF7	15556	-0.921	-0.4234	No
135	GPS1	15608	-0.951	-0.4249	No
136	MBIP	15706	-1.018	-0.4286	No
137	MAP4K3	15752	-1.048	-0.4298	No
138	ADRB2	15984	-1.226	-0.4395	No
139	ZDHHC13	16051	-1.284	-0.4415	No
140	CAMKK2	16123	-1.344	-0.4437	No
141	RIPK2	16143	-1.360	-0.4435	No
142	MIB2	16189	-1.401	-0.4445	No
143	DAPK1	16250	-1.448	-0.4461	No
144	DAXX	16329	-1.510	-0.4485	No
145	F2R	16595	-1.749	-0.4593	No
146	SHC1	16723	-1.857	-0.4637	No
147	RPS6KA4	16863	-1.997	-0.4685	No
148	TNIK	16901	-2.033	-0.4685	No
149	TRAF6	16980	-2.105	-0.4705	No
150	HCLS1	17013	-2.142	-0.4702	No
151	RHOA	17075	-2.199	-0.4713	No
152	DAPK3	17080	-2.200	-0.4697	No
153	MAP3K7IP1	17192	-2.295	-0.4730	No
154	MAPK9	17214	-2.310	-0.4721	No
155	TNFSF14	17226	-2.321	-0.4708	No
156	ERC1	17266	-2.356	-0.4707	No
157	IRAK2	17297	-2.389	-0.4701	No
158	HGS	17453	-2.539	-0.4753	No
159	SPRED1	17558	-2.657	-0.4779	No
160	CHUK	17643	-2.730	-0.4796	No
161	PAK1	17746	-2.826	-0.4821	No
162	MAPK14	17811	-2.903	-0.4827	No
163	STAT4	17839	-2.936	-0.4816	No
164	FKBP1A	17973	-3.076	-0.4852	No
165	OTUD7B	18039	-3.141	-0.4857	Yes
166	MAPK11	18040	-3.143	-0.4832	Yes
167	TMEM9B	18073	-3.182	-0.4821	Yes
168	SOCS2	18085	-3.196	-0.4801	Yes
169	MKNK2	18089	-3.199	-0.4777	Yes
170	RGS3	18102	-3.221	-0.4757	Yes
171	TICAM1	18233	-3.360	-0.4790	Yes
172	FADD	18270	-3.402	-0.4779	Yes
173	BCL3	18305	-3.430	-0.4767	Yes
174	MKNK1	18365	-3.498	-0.4766	Yes
175	OXSR1	18380	-3.517	-0.4745	Yes
176	IKBKG	18397	-3.530	-0.4724	Yes
177	DBNL	18517	-3.675	-0.4749	Yes
178	FYB	18658	-3.819	-0.4783	Yes
179	DUSP6	18680	-3.854	-0.4762	Yes
180	TBK1	18737	-3.926	-0.4757	Yes
181	SOCS6	18758	-3.954	-0.4734	Yes
182	MAP3K10	18760	-3.957	-0.4703	Yes
183	CXCR4	18871	-4.113	-0.4721	Yes
184	GPR177	18914	-4.167	-0.4707	Yes
185	IFNAR2	18945	-4.206	-0.4687	Yes
186	HIPK2	18997	-4.265	-0.4676	Yes
187	TRIP6	19029	-4.323	-0.4656	Yes
188	TRAF3IP2	19126	-4.464	-0.4665	Yes
189	PTEN	19245	-4.642	-0.4682	Yes
190	PINK1	19279	-4.705	-0.4660	Yes
191	MAP3K12	19326	-4.778	-0.4642	Yes
192	MAP3K11	19341	-4.796	-0.4611	Yes
193	SH2D3C	19505	-5.042	-0.4645	Yes
194	SCOTIN	19554	-5.132	-0.4626	Yes
195	CANT1	19559	-5.139	-0.4587	Yes
196	BIRC2	19566	-5.145	-0.4549	Yes
197	STAT5A	19672	-5.285	-0.4555	Yes
198	CLCF1	19735	-5.380	-0.4540	Yes
199	NDFIP1	19774	-5.439	-0.4515	Yes
200	MDFIC	19856	-5.585	-0.4507	Yes
201	LAX1	19906	-5.674	-0.4484	Yes
202	CC2D1A	20201	-6.272	-0.4570	Yes
203	BCL10	20231	-6.352	-0.4532	Yes
204	MAP2K7	20261	-6.417	-0.4494	Yes
205	SNF1LK2	20268	-6.428	-0.4446	Yes
206	MAP3K7IP2	20281	-6.446	-0.4400	Yes
207	ATP2C1	20325	-6.547	-0.4367	Yes
208	PIAS1	20382	-6.675	-0.4340	Yes
209	NDFIP2	20391	-6.700	-0.4290	Yes
210	MAP3K3	20422	-6.791	-0.4249	Yes
211	MAP3K13	20449	-6.853	-0.4206	Yes
212	PKN1	20455	-6.883	-0.4154	Yes
213	STAT2	20472	-6.911	-0.4106	Yes
214	EDARADD	20526	-7.013	-0.4074	Yes
215	CRKL	20555	-7.087	-0.4030	Yes
216	SPRED2	20599	-7.209	-0.3992	Yes
217	RHOH	20639	-7.326	-0.3952	Yes
218	MINK1	20643	-7.336	-0.3894	Yes
219	STAT3	20789	-7.787	-0.3899	Yes
220	STK4	20820	-7.881	-0.3850	Yes
221	SLC20A1	20830	-7.912	-0.3791	Yes
222	PPM1A	20886	-8.120	-0.3751	Yes
223	FLNA	20889	-8.130	-0.3687	Yes
224	DUSP16	20921	-8.252	-0.3635	Yes
225	WNK1	20997	-8.567	-0.3601	Yes
226	MAP4K4	21016	-8.644	-0.3540	Yes
227	TRAF2	21018	-8.648	-0.3472	Yes
228	RELA	21022	-8.671	-0.3404	Yes
229	TAOK3	21049	-8.758	-0.3346	Yes
230	DUSP2	21113	-8.980	-0.3303	Yes
231	MAPK8	21208	-9.408	-0.3271	Yes
232	SLC44A2	21236	-9.565	-0.3207	Yes
233	MADD	21274	-9.747	-0.3146	Yes
234	FYN	21301	-9.911	-0.3079	Yes
235	SQSTM1	21318	-9.993	-0.3006	Yes
236	SOCS1	21356	-10.225	-0.2941	Yes
237	GADD45B	21406	-10.572	-0.2879	Yes
238	MAP4K5	21442	-10.831	-0.2809	Yes
239	CFLAR	21465	-10.989	-0.2731	Yes
240	MAP2K4	21466	-10.991	-0.2643	Yes
241	SRPK2	21476	-11.046	-0.2559	Yes
242	TNFAIP3	21482	-11.148	-0.2472	Yes
243	CCM2	21538	-11.589	-0.2405	Yes
244	STAT5B	21655	-13.076	-0.2353	Yes
245	STAT1	21656	-13.091	-0.2249	Yes
246	TEC	21697	-13.757	-0.2157	Yes
247	TNFRSF1A	21703	-13.816	-0.2049	Yes
248	STK38	21758	-14.684	-0.1956	Yes
249	IKBKE	21809	-15.920	-0.1852	Yes
250	MIER1	21829	-16.787	-0.1726	Yes
251	TAOK2	21830	-16.810	-0.1592	Yes
252	IFNAR1	21831	-16.830	-0.1457	Yes
253	MAPK8IP3	21835	-16.890	-0.1324	Yes
254	MAP4K2	21842	-17.169	-0.1189	Yes
255	MARK2	21858	-17.748	-0.1054	Yes
256	STK17B	21860	-17.835	-0.0912	Yes
257	MALT1	21871	-18.066	-0.0772	Yes
258	NLK	21913	-21.118	-0.0622	Yes
259	FGF13	21947	-79.619	0.0000	Yes