Details for gene set PROTEIN_KINASE

Table: GSEA Results Summary

Dataset	set01_ATM_minus_versus_ATM_plus
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	PROTEIN_KINASE_ACTIVITY
Enrichment Score (ES)	-0.4554978
Normalized Enrichment Score (NES)	-1.9808226
Nominal p-value	0.0
FDR q-value	0.018438114
FWER p-Value	0.207

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PDGFRB	399	9.824	-0.0103	No
2	EPHB2	502	9.013	-0.0075	No
3	XRCC6BP1	519	8.900	-0.0009	No
4	FGFR4	606	8.388	0.0021	No
5	RYK	680	8.069	0.0054	No
6	PTK7	701	7.964	0.0110	No
7	CHEK2	707	7.951	0.0174	No
8	CSNK2B	803	7.574	0.0193	No
9	TRIM27	837	7.440	0.0239	No
10	RIPK4	1133	6.476	0.0157	No
11	RIPK3	1159	6.396	0.0198	No
12	PLK4	1306	6.023	0.0180	No
13	CDC42BPA	1415	5.784	0.0178	No
14	MAPK1	1423	5.768	0.0223	No
15	CSF1R	1432	5.745	0.0267	No
16	EGFR	1441	5.720	0.0310	No
17	PDK3	1488	5.612	0.0336	No
18	CCL2	1663	5.299	0.0299	No
19	TSSK4	1673	5.287	0.0339	No
20	TRIO	2114	4.664	0.0174	No
21	TGFA	2218	4.525	0.0164	No
22	PBK	2430	4.285	0.0103	No
23	RPS6KA3	2494	4.216	0.0108	No
24	PHKA1	2499	4.212	0.0141	No
25	EIF2AK2	2700	4.017	0.0082	No
26	MAPKAPK2	2720	3.998	0.0107	No
27	NEK2	2823	3.930	0.0092	No
28	TSSK6	2842	3.914	0.0116	No
29	MAPK12	2869	3.894	0.0136	No
30	ACVR1	3012	3.791	0.0102	No
31	TTN	3353	3.533	-0.0025	No
32	MAP3K6	3427	3.476	-0.0030	No
33	TTK	3448	3.461	-0.0011	No
34	MAST1	3467	3.451	0.0009	No
35	PLK1	3661	3.326	-0.0052	No
36	STK19	3697	3.311	-0.0041	No
37	LATS2	3716	3.300	-0.0022	No
38	TEK	3783	3.261	-0.0025	No
39	TYRO3	3877	3.216	-0.0042	No
40	VRK1	4077	3.102	-0.0108	No
41	FLT1	4151	3.068	-0.0116	No
42	UHMK1	4216	3.035	-0.0120	No
43	PRKCI	4238	3.023	-0.0105	No
44	VRK2	4288	3.001	-0.0103	No
45	MAP2K3	4337	2.980	-0.0100	No
46	MYLK	4466	2.925	-0.0135	No
47	LTK	4686	2.841	-0.0213	No
48	NRP2	4700	2.836	-0.0195	No
49	EIF2AK4	4802	2.792	-0.0219	No
50	ROR1	5110	2.683	-0.0338	No
51	MAP3K9	5225	2.645	-0.0369	No
52	RPS6KA2	5248	2.639	-0.0357	No
53	RPS6KA1	5264	2.635	-0.0342	No
54	RIPK1	5284	2.628	-0.0329	No
55	BRSK1	5357	2.606	-0.0341	No
56	MAPK10	5422	2.586	-0.0349	No
57	LIMK1	5462	2.569	-0.0346	No
58	INSR	5561	2.539	-0.0370	No
59	PDGFRA	5575	2.533	-0.0355	No
60	MET	5581	2.531	-0.0336	No
61	NTRK1	5612	2.523	-0.0329	No
62	STK3	5627	2.519	-0.0315	No
63	IRAK3	5862	2.443	-0.0403	No
64	CDK3	5999	2.396	-0.0445	No
65	DDR1	6027	2.387	-0.0438	No
66	ROR2	6153	2.350	-0.0476	No
67	KALRN	6274	2.311	-0.0513	No
68	MAPK4	6559	2.234	-0.0625	No
69	ACVRL1	6762	2.181	-0.0700	No
70	FGFR1	6855	2.152	-0.0725	No
71	MAPK15	6907	2.138	-0.0731	No
72	HUNK	6946	2.132	-0.0731	No
73	ACVR2A	6956	2.130	-0.0717	No
74	MAP3K7	6975	2.124	-0.0708	No
75	PDGFRL	7145	2.080	-0.0769	No
76	EPHA5	7169	2.072	-0.0762	No
77	SRPK1	7263	2.046	-0.0788	No
78	ACVR2B	7271	2.044	-0.0774	No
79	RPS6KA5	7337	2.027	-0.0788	No
80	TIE1	7436	2.002	-0.0816	No
81	EFNA3	7441	2.001	-0.0801	No
82	LATS1	7482	1.992	-0.0803	No
83	BRSK2	7492	1.989	-0.0791	No
84	BCKDK	7507	1.985	-0.0781	No
85	WNK2	7648	1.947	-0.0830	No
86	IRAK1	7859	1.892	-0.0911	No
87	NEK4	7878	1.888	-0.0904	No
88	TSSK3	8327	1.782	-0.1095	No
89	FRK	8587	1.722	-0.1201	No
90	MAP3K2	8636	1.709	-0.1209	No
91	ERBB4	8696	1.692	-0.1222	No
92	NEK11	8953	1.637	-0.1326	No
93	MST1R	9147	1.589	-0.1402	No
94	WNK3	9218	1.571	-0.1421	No
95	ERBB3	9243	1.565	-0.1420	No
96	ROCK2	9365	1.537	-0.1463	No
97	SGK2	9392	1.532	-0.1462	No
98	MARK1	9398	1.530	-0.1452	No
99	TRIB1	9436	1.520	-0.1456	No
100	MAP3K4	9437	1.520	-0.1444	No
101	ALK	9487	1.508	-0.1454	No
102	PRKD1	9525	1.498	-0.1458	No
103	BCR	9930	1.403	-0.1633	No
104	PTK6	10077	1.363	-0.1689	No
105	WNK4	10123	1.354	-0.1699	No
106	MERTK	10414	1.284	-0.1822	No
107	CCL4	10495	1.263	-0.1848	No
108	PRKCZ	10572	1.242	-0.1873	No
109	EFNA4	10574	1.242	-0.1863	No
110	ACVR1C	10669	1.222	-0.1896	No
111	DAPK2	10688	1.217	-0.1895	No
112	MAPK13	10765	1.197	-0.1920	No
113	CDK5	10811	1.185	-0.1931	No
114	CDK2	10991	1.139	-0.2004	No
115	STK36	11194	1.087	-0.2088	No
116	DDR2	11430	1.013	-0.2188	No
117	NEK6	11571	0.974	-0.2245	No
118	EFNB3	11718	0.928	-0.2304	No
119	ERBB2	11721	0.927	-0.2298	No
120	PDK4	12624	0.650	-0.2708	No
121	ERN2	13142	0.460	-0.2943	No
122	NUAK2	13262	0.412	-0.2994	No
123	TSSK2	13314	0.389	-0.3014	No
124	SNF1LK	13371	0.369	-0.3037	No
125	PIM1	13451	0.338	-0.3071	No
126	KDR	13460	0.335	-0.3072	No
127	FLT4	13543	0.297	-0.3107	No
128	FLT3	13666	0.239	-0.3161	No
129	PHKG2	14273	-0.074	-0.3440	No
130	GTF2H1	14585	-0.265	-0.3582	No
131	STK38L	14967	-0.508	-0.3753	No
132	NRP1	15214	-0.687	-0.3861	No
133	AXL	15466	-0.856	-0.3970	No
134	RPS6KC1	15540	-0.910	-0.3996	No
135	PLK3	15685	-1.005	-0.4054	No
136	MAP2K1	15741	-1.040	-0.4071	No
137	MAP4K3	15752	-1.048	-0.4066	No
138	TESK1	15849	-1.118	-0.4101	No
139	STK11	15968	-1.215	-0.4146	No
140	CDK9	15989	-1.229	-0.4145	No
141	CDC42BPB	16031	-1.265	-0.4153	No
142	CAMKK2	16123	-1.344	-0.4184	No
143	RIPK2	16143	-1.360	-0.4182	No
144	MUSK	16304	-1.493	-0.4243	No
145	CPNE3	16523	-1.676	-0.4330	No
146	TAF1	16532	-1.684	-0.4320	No
147	CDKL1	16876	-2.009	-0.4461	No
148	TNIK	16901	-2.033	-0.4455	No
149	PRKCH	16959	-2.083	-0.4464	No
150	DMPK	16977	-2.101	-0.4455	No
151	MAPK7	16999	-2.122	-0.4447	No
152	AKT1	17066	-2.193	-0.4459	No
153	DAPK3	17080	-2.200	-0.4447	No
154	TYK2	17095	-2.213	-0.4435	No
155	BRDT	17102	-2.222	-0.4420	No
156	MAP3K7IP1	17192	-2.295	-0.4442	No
157	MAPK9	17214	-2.310	-0.4432	No
158	CDC42BPG	17294	-2.382	-0.4449	No
159	IRAK2	17297	-2.389	-0.4430	No
160	MAPKAPK3	17357	-2.443	-0.4437	No
161	CIT	17582	-2.678	-0.4518	No
162	MAP2K6	17632	-2.723	-0.4518	No
163	CHUK	17643	-2.730	-0.4500	No
164	MARK4	17722	-2.802	-0.4513	No
165	PAK1	17746	-2.826	-0.4500	No
166	MAPK14	17811	-2.903	-0.4506	No
167	MAP3K8	17860	-2.954	-0.4504	No
168	RPS6KB2	17956	-3.060	-0.4522	No
169	CDK7	18002	-3.105	-0.4517	No
170	CRIM1	18015	-3.118	-0.4497	No
171	MAPK11	18040	-3.143	-0.4482	No
172	MKNK2	18089	-3.199	-0.4478	No
173	PHKA2	18186	-3.318	-0.4495	No
174	EXOSC10	18318	-3.438	-0.4527	Yes
175	CDK10	18341	-3.463	-0.4508	Yes
176	MKNK1	18365	-3.498	-0.4490	Yes
177	OXSR1	18380	-3.517	-0.4467	Yes
178	STK16	18441	-3.592	-0.4465	Yes
179	EIF2AK1	18481	-3.633	-0.4453	Yes
180	ILK	18512	-3.670	-0.4436	Yes
181	CLK1	18579	-3.733	-0.4436	Yes
182	GAK	18704	-3.882	-0.4461	Yes
183	MAP3K10	18760	-3.957	-0.4454	Yes
184	ERN1	18848	-4.074	-0.4460	Yes
185	ATM	18851	-4.077	-0.4427	Yes
186	PAK2	18865	-4.102	-0.4399	Yes
187	CSNK1G2	18900	-4.144	-0.4381	Yes
188	SGK3	18946	-4.207	-0.4367	Yes
189	EIF2AK3	18978	-4.241	-0.4346	Yes
190	ALS2CR2	19089	-4.405	-0.4360	Yes
191	BRD2	19233	-4.628	-0.4388	Yes
192	TESK2	19259	-4.659	-0.4361	Yes
193	PINK1	19279	-4.705	-0.4331	Yes
194	PRKAG1	19286	-4.710	-0.4295	Yes
195	MAP3K12	19326	-4.778	-0.4273	Yes
196	MAP3K11	19341	-4.796	-0.4240	Yes
197	PXK	19343	-4.802	-0.4201	Yes
198	PRKD3	19453	-4.974	-0.4210	Yes
199	ULK1	19480	-5.004	-0.4180	Yes
200	CSNK1D	19547	-5.118	-0.4168	Yes
201	CSNK1A1	19558	-5.138	-0.4131	Yes
202	PRKX	19622	-5.230	-0.4116	Yes
203	KIT	19722	-5.366	-0.4118	Yes
204	CDK5R1	19785	-5.468	-0.4101	Yes
205	PDK1	19800	-5.491	-0.4062	Yes
206	CLK2	19812	-5.514	-0.4021	Yes
207	COL4A3BP	19878	-5.631	-0.4005	Yes
208	PRKACB	19908	-5.677	-0.3971	Yes
209	ACVR1B	19911	-5.677	-0.3925	Yes
210	CSNK2A2	19914	-5.695	-0.3879	Yes
211	TNK2	19917	-5.699	-0.3833	Yes
212	ROCK1	20004	-5.882	-0.3824	Yes
213	TLK1	20203	-6.276	-0.3863	Yes
214	AKT2	20209	-6.297	-0.3813	Yes
215	TRIB2	20241	-6.377	-0.3775	Yes
216	MAP2K7	20261	-6.417	-0.3731	Yes
217	SNF1LK2	20268	-6.428	-0.3680	Yes
218	TXK	20361	-6.619	-0.3668	Yes
219	LIMK2	20416	-6.771	-0.3637	Yes
220	STK10	20418	-6.774	-0.3581	Yes
221	MAP3K3	20422	-6.791	-0.3526	Yes
222	PIM2	20446	-6.848	-0.3480	Yes
223	MAP3K13	20449	-6.853	-0.3425	Yes
224	CRKL	20555	-7.087	-0.3414	Yes
225	MAPKAPK5	20596	-7.204	-0.3373	Yes
226	DYRK1A	20638	-7.321	-0.3332	Yes
227	MINK1	20643	-7.336	-0.3273	Yes
228	PRKCE	20653	-7.365	-0.3216	Yes
229	PDK2	20750	-7.630	-0.3197	Yes
230	STK4	20820	-7.881	-0.3164	Yes
231	CSNK2A1	20926	-8.269	-0.3144	Yes
232	WNK1	20997	-8.567	-0.3105	Yes
233	MAPK6	21006	-8.592	-0.3038	Yes
234	MAP4K4	21016	-8.644	-0.2971	Yes
235	IGF2R	21017	-8.646	-0.2899	Yes
236	TGFBR2	21043	-8.737	-0.2838	Yes
237	TAOK3	21049	-8.758	-0.2768	Yes
238	LMTK2	21182	-9.262	-0.2752	Yes
239	MAPK8	21208	-9.408	-0.2686	Yes
240	ITK	21334	-10.083	-0.2660	Yes
241	TGFBR1	21368	-10.287	-0.2591	Yes
242	MAP4K5	21442	-10.831	-0.2535	Yes
243	GSK3B	21455	-10.935	-0.2450	Yes
244	SRPK2	21476	-11.046	-0.2368	Yes
245	EPHB6	21527	-11.508	-0.2295	Yes
246	SNRK	21532	-11.545	-0.2202	Yes
247	TLK2	21642	-12.867	-0.2146	Yes
248	DYRK2	21648	-12.985	-0.2041	Yes
249	HIPK3	21676	-13.309	-0.1943	Yes
250	PTK2B	21693	-13.678	-0.1837	Yes
251	TEC	21697	-13.757	-0.1725	Yes
252	STK38	21758	-14.684	-0.1631	Yes
253	SKAP1	21774	-15.080	-0.1513	Yes
254	IGF1R	21784	-15.295	-0.1391	Yes
255	CSNK1E	21807	-15.890	-0.1269	Yes
256	IKBKE	21809	-15.920	-0.1138	Yes
257	TAOK2	21830	-16.810	-0.1008	Yes
258	MAP4K2	21842	-17.169	-0.0871	Yes
259	CLK3	21849	-17.494	-0.0730	Yes
260	MARK2	21858	-17.748	-0.0586	Yes
261	STK17B	21860	-17.835	-0.0439	Yes
262	PRKCB1	21866	-17.985	-0.0293	Yes
263	PDPK1	21879	-18.696	-0.0144	Yes
264	NLK	21913	-21.118	0.0016	Yes