Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_transDMpreB.cls#transDMproB_versus_transDMpreB_repos |
| Upregulated in class | transDMproB |
| GeneSet | TCRPATHWAY |
| Enrichment Score (ES) | 0.7299401 |
| Normalized Enrichment Score (NES) | 1.5725844 |
| Nominal p-value | 0.013539651 |
| FDR q-value | 0.274299 |
| FWER p-Value | 0.661 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LCK | 15746 | 27 | 9.283 | 0.1704 | Yes | ||
| 2 | LAT | 17643 | 124 | 7.317 | 0.3006 | Yes | ||
| 3 | VAV1 | 23173 | 461 | 4.594 | 0.3676 | Yes | ||
| 4 | PPP3CC | 21763 | 894 | 3.021 | 0.4003 | Yes | ||
| 5 | RASA1 | 10174 | 929 | 2.929 | 0.4526 | Yes | ||
| 6 | CALM3 | 8682 | 973 | 2.818 | 0.5025 | Yes | ||
| 7 | PTPN7 | 11500 | 1095 | 2.511 | 0.5425 | Yes | ||
| 8 | PPP3CB | 5285 | 1113 | 2.475 | 0.5874 | Yes | ||
| 9 | JUN | 15832 | 1203 | 2.302 | 0.6252 | Yes | ||
| 10 | NFKB1 | 15160 | 1393 | 1.965 | 0.6514 | Yes | ||
| 11 | PRKCB1 | 1693 9574 | 1672 | 1.605 | 0.6661 | Yes | ||
| 12 | CALM2 | 8681 | 1752 | 1.490 | 0.6895 | Yes | ||
| 13 | RAC1 | 16302 | 1922 | 1.265 | 0.7038 | Yes | ||
| 14 | NFATC1 | 23398 1999 5167 9455 1985 1957 | 2241 | 0.988 | 0.7050 | Yes | ||
| 15 | RELA | 23783 | 2280 | 0.956 | 0.7206 | Yes | ||
| 16 | MAP3K1 | 21348 | 2404 | 0.849 | 0.7297 | Yes | ||
| 17 | GRB2 | 20149 | 2633 | 0.675 | 0.7299 | Yes | ||
| 18 | NFATC3 | 5169 | 3159 | 0.379 | 0.7087 | No | ||
| 19 | FOS | 21202 | 3200 | 0.360 | 0.7132 | No | ||
| 20 | FYN | 3375 3395 20052 | 3206 | 0.359 | 0.7196 | No | ||
| 21 | CD3D | 19473 | 3602 | 0.234 | 0.7027 | No | ||
| 22 | MAPK3 | 6458 11170 | 4819 | 0.071 | 0.6385 | No | ||
| 23 | PRKCA | 20174 | 4927 | 0.066 | 0.6340 | No | ||
| 24 | SHC1 | 9813 9812 5430 | 4928 | 0.066 | 0.6352 | No | ||
| 25 | PIK3R1 | 3170 | 5108 | 0.059 | 0.6267 | No | ||
| 26 | SOS1 | 5476 | 5642 | 0.043 | 0.5988 | No | ||
| 27 | PIK3CA | 9562 | 5729 | 0.040 | 0.5949 | No | ||
| 28 | CD3G | 19139 | 6008 | 0.034 | 0.5805 | No | ||
| 29 | SYT1 | 5565 | 7160 | 0.014 | 0.5188 | No | ||
| 30 | CD3E | 8714 | 7771 | 0.006 | 0.4861 | No | ||
| 31 | MAP2K4 | 20405 | 9480 | -0.016 | 0.3944 | No | ||
| 32 | PPP3CA | 1863 5284 | 10076 | -0.024 | 0.3629 | No | ||
| 33 | TRB@ | 1157 | 10351 | -0.028 | 0.3486 | No | ||
| 34 | NFATC4 | 22002 | 10479 | -0.030 | 0.3423 | No | ||
| 35 | NFATC2 | 5168 2866 | 10498 | -0.030 | 0.3419 | No | ||
| 36 | PLCG1 | 14753 | 10828 | -0.036 | 0.3249 | No | ||
| 37 | CALM1 | 21184 | 11385 | -0.046 | 0.2958 | No | ||
| 38 | ZAP70 | 14271 4042 | 13513 | -0.123 | 0.1836 | No | ||
| 39 | RAF1 | 17035 | 15103 | -0.349 | 0.1045 | No | ||
| 40 | MAPK8 | 6459 | 15940 | -0.722 | 0.0729 | No | ||
| 41 | MAP2K1 | 19082 | 15996 | -0.765 | 0.0841 | No | ||
| 42 | HRAS | 4868 | 16218 | -0.935 | 0.0895 | No | ||
| 43 | NFKBIA | 21065 | 17327 | -2.139 | 0.0694 | No |
