Details for gene set HSA04010_MAPK_SIGNALING

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB_repos
Phenotype	phenotype_transDMproB_versus_transDMpreB.cls#transDMproB_versus_transDMpreB_repos
Upregulated in class	transDMproB
GeneSet	HSA04010_MAPK_SIGNALING_PATHWAY
Enrichment Score (ES)	0.5662532
Normalized Enrichment Score (NES)	1.5134913
Nominal p-value	0.0
FDR q-value	0.2380604
FWER p-Value	0.945

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MAPKAPK2	13838	96	7.676	0.0307	Yes
2	DUSP1	23061	191	6.471	0.0559	Yes
3	GADD45A	17129	196	6.435	0.0859	Yes
4	MAP3K3	20626	266	5.885	0.1097	Yes
5	RRAS2	12431	366	5.092	0.1281	Yes
6	PRKACB	15140	377	5.058	0.1513	Yes
7	RASGRP2	9693	422	4.810	0.1714	Yes
8	DUSP2	14865	548	4.171	0.1842	Yes
9	DDIT3	19857	573	4.086	0.2020	Yes
10	MAPK1	1642 11167	646	3.755	0.2157	Yes
11	TGFB1	18332	647	3.751	0.2332	Yes
12	DUSP6	19891 3399	663	3.690	0.2497	Yes
13	TRAF6	5797 14940	701	3.574	0.2644	Yes
14	MAP4K3	22887	754	3.376	0.2774	Yes
15	MAPK14	23313	828	3.176	0.2883	Yes
16	MAP3K7IP2	19827	837	3.156	0.3027	Yes
17	PPP3CC	21763	894	3.021	0.3138	Yes
18	AKT3	13739 982	908	2.985	0.3271	Yes
19	RAC2	22217	922	2.950	0.3402	Yes
20	RASA1	10174	929	2.929	0.3536	Yes
21	PPM1B	5280 1567 5281	985	2.786	0.3636	Yes
22	KRAS	9247	987	2.779	0.3766	Yes
23	NFKB2	23810	1024	2.671	0.3871	Yes
24	CRKL	4560	1082	2.544	0.3959	Yes
25	PTPN7	11500	1095	2.511	0.4071	Yes
26	PPP3CB	5285	1113	2.475	0.4177	Yes
27	CACNA2D1	8676	1124	2.462	0.4287	Yes
28	MAP4K2	6457	1131	2.455	0.4399	Yes
29	MAPK9	1233 20903 1383	1138	2.444	0.4510	Yes
30	RRAS	18256	1171	2.376	0.4604	Yes
31	JUN	15832	1203	2.302	0.4695	Yes
32	MAP4K4	11241	1341	2.060	0.4717	Yes
33	NFKB1	15160	1393	1.965	0.4781	Yes
34	MKNK2	3299 9392	1452	1.891	0.4838	Yes
35	RPS6KA4	23804	1467	1.866	0.4918	Yes
36	CASP3	8693	1487	1.828	0.4993	Yes
37	STK3	7084	1530	1.776	0.5054	Yes
38	MAP3K14	11998	1575	1.713	0.5110	Yes
39	RAP1B	10083	1597	1.694	0.5178	Yes
40	MAP3K5	20079 11166	1636	1.636	0.5234	Yes
41	MEF2C	3204 9378	1666	1.612	0.5294	Yes
42	PRKCB1	1693 9574	1672	1.605	0.5366	Yes
43	STK4	14743	1681	1.594	0.5436	Yes
44	CDC25B	14841	1746	1.499	0.5472	Yes
45	ARRB2	20806	1919	1.273	0.5438	Yes
46	RAC1	16302	1922	1.265	0.5496	Yes
47	MAP2K3	20856	1966	1.207	0.5529	Yes
48	SOS2	21049	2002	1.166	0.5565	Yes
49	MAP2K5	19088	2016	1.152	0.5612	Yes
50	MAP3K4	23126	2022	1.147	0.5663	Yes
51	CACNB2	4466 8678	2250	0.982	0.5585	No
52	GNG12	4789	2301	0.931	0.5601	No
53	MAP3K1	21348	2404	0.849	0.5586	No
54	ACVR1B	4335 22353	2478	0.793	0.5583	No
55	EGF	15169	2502	0.778	0.5607	No
56	GRB2	20149	2633	0.675	0.5568	No
57	IL1B	14431	2737	0.602	0.5540	No
58	CD14	23452	2751	0.590	0.5561	No
59	PAK1	9527	2776	0.568	0.5574	No
60	RASGRP4	6119	3060	0.427	0.5440	No
61	MYC	22465 9435	3081	0.419	0.5449	No
62	FGFR2	1917 4722 1119	3116	0.398	0.5449	No
63	MAPK13	23314	3125	0.394	0.5463	No
64	FOS	21202	3200	0.360	0.5440	No
65	GNA12	9023	3258	0.338	0.5425	No
66	NF1	5165	3387	0.293	0.5369	No
67	ELK4	8895 4664 3937	3395	0.291	0.5379	No
68	PPM1A	5279 9607	3450	0.272	0.5362	No
69	CACNA1F	12054 24393	3704	0.209	0.5234	No
70	FAS	23881 3750	3713	0.208	0.5239	No
71	PDGFRB	23539	3809	0.189	0.5197	No
72	CACNA2D2	7154	3879	0.174	0.5167	No
73	ARRB1	3890 8465 18178 4276	3883	0.174	0.5174	No
74	PDGFA	5237	3898	0.170	0.5174	No
75	DUSP4	18632 3820	3906	0.168	0.5178	No
76	FGF1	1994 23447	4015	0.150	0.5126	No
77	MAP3K8	23495	4211	0.121	0.5026	No
78	TRAF2	14657	4297	0.111	0.4985	No
79	PLA2G5	9583	4390	0.102	0.4940	No
80	PLA2G1B	9581	4482	0.094	0.4895	No
81	FGF22	12468 7385	4493	0.093	0.4893	No
82	TNF	23004	4572	0.087	0.4855	No
83	CACNA1E	4465	4595	0.085	0.4847	No
84	MAPK7	1381 20414	4612	0.084	0.4842	No
85	TGFBR1	16213 10165 5745	4776	0.074	0.4757	No
86	MAPK3	6458 11170	4819	0.071	0.4738	No
87	PRKCA	20174	4927	0.066	0.4682	No
88	DUSP7	10661	4943	0.065	0.4677	No
89	CRK	4559 1249	5115	0.059	0.4587	No
90	MAP3K6	16054	5162	0.058	0.4565	No
91	MAP3K10	3831 17916	5271	0.054	0.4509	No
92	FGF21	17830	5450	0.048	0.4414	No
93	FGF9	8966	5494	0.047	0.4393	No
94	DUSP10	4003 14016	5521	0.046	0.4381	No
95	FGFR4	3226	5533	0.046	0.4377	No
96	IL1R2	14265	5536	0.046	0.4378	No
97	CACNA1G	1237 940 20292	5593	0.044	0.4350	No
98	PRKACA	18549 3844	5625	0.043	0.4335	No
99	SOS1	5476	5642	0.043	0.4328	No
100	PPP3R1	9611 489	5812	0.038	0.4238	No
101	MAP3K13	22814	5881	0.037	0.4203	No
102	FGF18	4721 1351	5899	0.036	0.4195	No
103	DUSP16	1004 7699	6031	0.034	0.4125	No
104	FGF4	8964	6294	0.028	0.3984	No
105	PRKX	9619 5290	6319	0.028	0.3972	No
106	CACNG7	13497	6337	0.027	0.3964	No
107	ACVR1C	14585	6341	0.027	0.3964	No
108	PLA2G10	22658	6355	0.027	0.3958	No
109	RASGRP1	5360 14476 9694	6386	0.026	0.3943	No
110	TGFBR2	2994 3001 10167	6456	0.025	0.3907	No
111	PDGFB	22199 2311	6490	0.025	0.3890	No
112	FGF16	24270	6564	0.023	0.3851	No
113	TAOK2	10610 3794	6700	0.021	0.3779	No
114	MAP3K7IP1	2193 2171 22419	6756	0.020	0.3750	No
115	CDC42	4503 8722 4504 2465	6775	0.020	0.3741	No
116	PLA2G12B	20016	7065	0.016	0.3585	No
117	DUSP8	9493	7183	0.014	0.3522	No
118	MAPT	9420 1347	7403	0.011	0.3403	No
119	CACNB4	4467	7469	0.010	0.3368	No
120	FASLG	13789	7511	0.010	0.3346	No
121	CACNA1H	23077	7538	0.009	0.3332	No
122	AKT2	4365 4366	7867	0.004	0.3154	No
123	MAP2K1IP1	12158	7868	0.004	0.3154	No
124	CACNG4	20176	8000	0.002	0.3083	No
125	RAP1A	8467	8097	0.001	0.3031	No
126	FGF7	8965	8131	0.001	0.3013	No
127	RAC3	20561	8167	0.000	0.2994	No
128	CACNG6	7033	8185	-0.000	0.2985	No
129	DUSP9	24307	8206	-0.000	0.2974	No
130	PLA2G3	20968	8602	-0.005	0.2759	No
131	NR4A1	9099	8659	-0.006	0.2729	No
132	CACNG3	12029	8907	-0.009	0.2595	No
133	PLA2G2A	16017	9068	-0.011	0.2509	No
134	PLA2G4A	13809	9334	-0.015	0.2365	No
135	MAP2K4	20405	9480	-0.016	0.2287	No
136	MAP2K7	6453	9569	-0.017	0.2240	No
137	CACNG8	13498	9837	-0.021	0.2096	No
138	RPS6KA3	8490	9929	-0.022	0.2047	No
139	PPP3CA	1863 5284	10076	-0.024	0.1969	No
140	RPS6KA6	12458	10190	-0.026	0.1909	No
141	CACNG5	1339 20175	10233	-0.026	0.1887	No
142	FGF12	1723 22621	10239	-0.026	0.1885	No
143	EVI1	4689 8926	10262	-0.027	0.1875	No
144	IL1A	4915	10427	-0.029	0.1787	No
145	NFATC4	22002	10479	-0.030	0.1761	No
146	NFATC2	5168 2866	10498	-0.030	0.1752	No
147	MOS	16254	10562	-0.032	0.1719	No
148	NTF5	18248	10803	-0.035	0.1590	No
149	FLNC	4302 8510	10880	-0.037	0.1551	No
150	BDNF	14926 2797	10908	-0.037	0.1538	No
151	PDGFRA	16824	10979	-0.039	0.1502	No
152	MAPK8IP3	11402 23080	11012	-0.039	0.1486	No
153	EGFR	1329 20944	11172	-0.042	0.1401	No
154	FGF11	20383	11253	-0.044	0.1360	No
155	PLA2G2E	16016	11297	-0.045	0.1339	No
156	FGF14	21716 3005 3463	11298	-0.045	0.1341	No
157	FGFR1	3789 8968	11386	-0.046	0.1296	No
158	MAPKAPK5	16387	11533	-0.050	0.1219	No
159	CACNA1B	8673 4462	11635	-0.052	0.1166	No
160	MAPK10	11169	11773	-0.055	0.1094	No
161	RPS6KA2	9759 9758	11853	-0.057	0.1054	No
162	CACNB3	22373 8679	11889	-0.058	0.1037	No
163	MRAS	9409	11960	-0.060	0.1002	No
164	RPS6KA5	2076 21005	12255	-0.068	0.0845	No
165	PTPRR	3436 19876	12276	-0.069	0.0838	No
166	FGF5	16785	12300	-0.070	0.0828	No
167	CACNA1D	4464 8675	12399	-0.072	0.0778	No
168	PPP3R2	9612	12439	-0.074	0.0761	No
169	FGF20	18892	12495	-0.076	0.0734	No
170	CACNA1A	4461	12509	-0.077	0.0731	No
171	NTRK1	15299	12535	-0.078	0.0721	No
172	NGFB	15476	12719	-0.084	0.0625	No
173	FGF8	23656	12761	-0.085	0.0607	No
174	PLA2G2D	16018	12823	-0.088	0.0578	No
175	SRF	22961 1597	12824	-0.088	0.0582	No
176	FGFR3	8969 3566	12854	-0.089	0.0570	No
177	NTRK2	9491	13264	-0.108	0.0353	No
178	FGF10	4719 8962	13285	-0.109	0.0347	No
179	AKT1	8568	13376	-0.114	0.0303	No
180	RASGRF1	3050 19357	13416	-0.117	0.0288	No
181	GADD45G	21637	13508	-0.123	0.0244	No
182	TGFB3	10161	13539	-0.125	0.0233	No
183	DAXX	23290	13639	-0.133	0.0186	No
184	FGF2	15608	13686	-0.136	0.0167	No
185	NTF3	16991	13693	-0.137	0.0170	No
186	IKBKG	2570 2562 4908	13814	-0.147	0.0112	No
187	CACNA1C	1158 1166 24464 4463 8674	13866	-0.152	0.0091	No
188	DUSP14	12124	14321	-0.199	-0.0146	No
189	PTPN5	17817	14333	-0.201	-0.0143	No
190	CACNA2D3	8677	14429	-0.215	-0.0185	No
191	MAPK8IP2	77	14533	-0.230	-0.0230	No
192	MAPK11	2264 9618 22163	14624	-0.244	-0.0267	No
193	PLA2G6	22209	14648	-0.248	-0.0268	No
194	FGF23	17275	14728	-0.259	-0.0299	No
195	FGF17	21757	14749	-0.264	-0.0298	No
196	TNFRSF1A	1181 10206	14854	-0.284	-0.0341	No
197	ATF2	4418 2759	14872	-0.288	-0.0337	No
198	MAP3K2	11165	14901	-0.295	-0.0338	No
199	RASGRF2	21397	14957	-0.307	-0.0354	No
200	IL1R1	14264 3987	14990	-0.314	-0.0356	No
201	RASA2	4329	15057	-0.335	-0.0377	No
202	RAF1	17035	15103	-0.349	-0.0385	No
203	TGFB2	5743	15170	-0.369	-0.0403	No
204	DUSP3	1358 13022	15171	-0.369	-0.0386	No
205	MAX	21034	15303	-0.411	-0.0438	No
206	MAP2K6	20614 1414	15318	-0.416	-0.0426	No
207	CACNG1	20177	15327	-0.420	-0.0411	No
208	RPS6KA1	15725	15336	-0.422	-0.0396	No
209	MAP3K7	16255	15341	-0.423	-0.0378	No
210	STMN1	9261	15365	-0.429	-0.0370	No
211	PAK2	10310 5875	15483	-0.476	-0.0412	No
212	RASGRP3	10767	15512	-0.487	-0.0404	No
213	PLA2G2F	15700	15534	-0.500	-0.0392	No
214	CACNB1	1443 1304	15607	-0.529	-0.0406	No
215	FGF3	17997	15610	-0.530	-0.0383	No
216	FGF13	4720 8963 2627	15696	-0.575	-0.0402	No
217	ATF4	22417 2239	15807	-0.634	-0.0432	No
218	MAP3K12	6454 11164	15918	-0.704	-0.0459	No
219	MAPK8	6459	15940	-0.722	-0.0437	No
220	MAP2K1	19082	15996	-0.765	-0.0431	No
221	NLK	5179 5178	15999	-0.766	-0.0396	No
222	TP53	20822	16099	-0.845	-0.0410	No
223	CACNA1S	14111	16162	-0.890	-0.0402	No
224	HRAS	4868	16218	-0.935	-0.0388	No
225	PLA2G12A	1782 7281 1839	16245	-0.963	-0.0357	No
226	NRAS	5191	16623	-1.268	-0.0503	No
227	MAP2K2	19933	16752	-1.439	-0.0505	No
228	MKNK1	2504	16799	-1.480	-0.0461	No
229	MAPKAPK3	19003	16871	-1.572	-0.0426	No
230	MAPK12	2182 2215 22164	16989	-1.692	-0.0411	No
231	FLNB	13742	17156	-1.892	-0.0412	No
232	PPP5C	17952	17311	-2.119	-0.0397	No
233	FLNA	24129	17452	-2.360	-0.0362	No
234	IKBKB	4907	17623	-2.702	-0.0328	No
235	GADD45B	19935	17855	-3.198	-0.0304	No
236	CHUK	23665	18013	-3.687	-0.0217	No
237	MAP4K1	18313	18407	-5.384	-0.0179	No
238	ECSIT	11248	18502	-6.227	0.0062	No