Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_transDMpreB.cls#transDMproB_versus_transDMpreB_repos |
| Upregulated in class | transDMpreB |
| GeneSet | HSA00240_PYRIMIDINE_METABOLISM |
| Enrichment Score (ES) | -0.6989574 |
| Normalized Enrichment Score (NES) | -1.6820873 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.021943536 |
| FWER p-Value | 0.094 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | DCK | 16808 | 138 | 7.202 | 0.0380 | No | ||
| 2 | RRM2 | 5401 5400 | 611 | 3.902 | 0.0372 | No | ||
| 3 | ZNRD1 | 1491 22987 | 696 | 3.595 | 0.0553 | No | ||
| 4 | NT5C2 | 3768 8052 | 1507 | 1.802 | 0.0230 | No | ||
| 5 | UCK1 | 10254 5831 10253 | 1574 | 1.716 | 0.0302 | No | ||
| 6 | TK2 | 18779 | 1772 | 1.459 | 0.0288 | No | ||
| 7 | POLD1 | 17847 | 2113 | 1.052 | 0.0171 | No | ||
| 8 | NP | 22027 9597 5273 5274 | 2199 | 1.000 | 0.0189 | No | ||
| 9 | RRM1 | 18163 | 2409 | 0.847 | 0.0129 | No | ||
| 10 | NUDT2 | 16239 | 2714 | 0.615 | 0.0004 | No | ||
| 11 | ENTPD5 | 4497 | 2918 | 0.495 | -0.0074 | No | ||
| 12 | POLD4 | 12822 | 3141 | 0.386 | -0.0170 | No | ||
| 13 | NME7 | 926 4101 14070 3986 3946 931 | 3955 | 0.161 | -0.0598 | No | ||
| 14 | UPP1 | 20947 1385 | 3960 | 0.160 | -0.0590 | No | ||
| 15 | POLR2I | 12839 | 4567 | 0.087 | -0.0911 | No | ||
| 16 | CTPS2 | 12060 2571 | 5958 | 0.035 | -0.1659 | No | ||
| 17 | POLA1 | 24112 | 6832 | 0.019 | -0.2128 | No | ||
| 18 | ENTPD1 | 4495 | 7360 | 0.012 | -0.2412 | No | ||
| 19 | DPYD | 15437 | 7772 | 0.006 | -0.2633 | No | ||
| 20 | DPYS | 22305 | 8671 | -0.006 | -0.3117 | No | ||
| 21 | ENTPD3 | 19266 | 8933 | -0.010 | -0.3257 | No | ||
| 22 | ITPA | 9193 | 8996 | -0.010 | -0.3290 | No | ||
| 23 | POLR2B | 16817 | 9561 | -0.017 | -0.3593 | No | ||
| 24 | POLR3K | 12447 7372 | 10060 | -0.024 | -0.3860 | No | ||
| 25 | POLE2 | 21053 | 10840 | -0.036 | -0.4278 | No | ||
| 26 | AICDA | 17295 1087 | 10954 | -0.038 | -0.4337 | No | ||
| 27 | POLR2C | 9750 | 11135 | -0.042 | -0.4431 | No | ||
| 28 | ENTPD8 | 12996 | 12216 | -0.067 | -0.5009 | No | ||
| 29 | UPB1 | 19988 3389 | 12329 | -0.070 | -0.5065 | No | ||
| 30 | CDA | 15702 | 12424 | -0.073 | -0.5111 | No | ||
| 31 | RRM2B | 6902 6903 11801 | 12478 | -0.075 | -0.5135 | No | ||
| 32 | TXNRD1 | 19923 | 13170 | -0.103 | -0.5502 | No | ||
| 33 | NT5C1B | 21315 | 13461 | -0.120 | -0.5650 | No | ||
| 34 | CANT1 | 13304 | 13957 | -0.160 | -0.5907 | No | ||
| 35 | ENTPD6 | 4496 2678 | 14502 | -0.225 | -0.6186 | No | ||
| 36 | UPP2 | 15009 13346 8032 | 14940 | -0.303 | -0.6403 | No | ||
| 37 | POLD3 | 17742 | 15292 | -0.408 | -0.6567 | No | ||
| 38 | NT5E | 19360 18702 | 15361 | -0.428 | -0.6576 | No | ||
| 39 | NME4 | 23065 1577 | 15373 | -0.432 | -0.6555 | No | ||
| 40 | PNPT1 | 20936 | 15541 | -0.503 | -0.6613 | No | ||
| 41 | NT5C3 | 17136 | 15775 | -0.616 | -0.6700 | No | ||
| 42 | TYMS | 5810 5809 3606 3598 | 15922 | -0.710 | -0.6734 | No | ||
| 43 | POLE4 | 12441 | 15943 | -0.724 | -0.6699 | No | ||
| 44 | POLR2A | 5394 | 16021 | -0.780 | -0.6691 | No | ||
| 45 | POLR1A | 9749 5393 | 16138 | -0.877 | -0.6699 | No | ||
| 46 | POLR1D | 3593 3658 16623 | 16315 | -1.000 | -0.6731 | No | ||
| 47 | ECGF1 | 22160 | 16512 | -1.147 | -0.6764 | No | ||
| 48 | TK1 | 1457 10182 5762 | 16580 | -1.227 | -0.6723 | No | ||
| 49 | POLR2K | 9413 | 17076 | -1.786 | -0.6877 | Yes | ||
| 50 | POLR2E | 3325 19699 | 17108 | -1.814 | -0.6779 | Yes | ||
| 51 | POLR2G | 23753 | 17143 | -1.872 | -0.6679 | Yes | ||
| 52 | POLR3A | 21900 | 17377 | -2.234 | -0.6664 | Yes | ||
| 53 | TXNRD2 | 22829 1649 | 17442 | -2.343 | -0.6551 | Yes | ||
| 54 | POLR3H | 13460 8135 | 17517 | -2.467 | -0.6435 | Yes | ||
| 55 | PRIM1 | 19847 | 17631 | -2.714 | -0.6325 | Yes | ||
| 56 | DTYMK | 5776 | 17636 | -2.721 | -0.6155 | Yes | ||
| 57 | POLR2J | 16672 | 17714 | -2.890 | -0.6015 | Yes | ||
| 58 | ENTPD4 | 7449 | 17716 | -2.897 | -0.5832 | Yes | ||
| 59 | NME6 | 3139 19297 | 17843 | -3.167 | -0.5700 | Yes | ||
| 60 | NT5M | 8345 4175 | 17914 | -3.392 | -0.5524 | Yes | ||
| 61 | RFC5 | 13005 7791 | 18005 | -3.668 | -0.5341 | Yes | ||
| 62 | POLE3 | 7200 | 18084 | -3.862 | -0.5140 | Yes | ||
| 63 | POLE | 16755 | 18111 | -3.955 | -0.4904 | Yes | ||
| 64 | POLA2 | 23988 | 18195 | -4.278 | -0.4679 | Yes | ||
| 65 | POLR2H | 10888 | 18316 | -4.847 | -0.4438 | Yes | ||
| 66 | NT5C | 20151 | 18338 | -5.003 | -0.4134 | Yes | ||
| 67 | POLD2 | 20537 | 18438 | -5.603 | -0.3834 | Yes | ||
| 68 | DHODH | 7152 | 18486 | -6.100 | -0.3474 | Yes | ||
| 69 | UMPS | 22606 1760 | 18497 | -6.201 | -0.3088 | Yes | ||
| 70 | CAD | 16886 | 18503 | -6.237 | -0.2698 | Yes | ||
| 71 | NME2 | 9468 | 18508 | -6.307 | -0.2302 | Yes | ||
| 72 | POLR3B | 12875 | 18537 | -6.688 | -0.1895 | Yes | ||
| 73 | NME1 | 9467 | 18540 | -6.712 | -0.1473 | Yes | ||
| 74 | CTPS | 2514 15772 | 18574 | -7.597 | -0.1011 | Yes | ||
| 75 | DCTD | 18620 | 18577 | -7.631 | -0.0531 | Yes | ||
| 76 | POLR1B | 14857 | 18598 | -8.740 | 0.0010 | Yes |
