Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB_repos
Phenotype	phenotype_transDMproB_versus_transDMpreB.cls#transDMproB_versus_transDMpreB_repos
Upregulated in class	transDMpreB
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	-0.57910115
Normalized Enrichment Score (NES)	-1.4910482
Nominal p-value	0.008528785
FDR q-value	0.19725741
FWER p-Value	0.98

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IMPDH1	17197 1131	3	10.854	0.0481	No
2	GMPR	21651	8	10.382	0.0941	No
3	DCK	16808	138	7.202	0.1192	No
4	RRM2	5401 5400	611	3.902	0.1110	No
5	ZNRD1	1491 22987	696	3.595	0.1225	No
6	PAPSS1	15419	859	3.110	0.1275	No
7	ADA	2703 14361	892	3.026	0.1393	No
8	PDE2A	18170	936	2.906	0.1499	No
9	DGUOK	17099 1041	1257	2.191	0.1423	No
10	PDE4B	9543	1426	1.932	0.1418	No
11	NT5C2	3768 8052	1507	1.802	0.1455	No
12	ADCY9	22680	1973	1.195	0.1257	No
13	PDE3B	5236	2005	1.164	0.1292	No
14	XDH	22897	2084	1.091	0.1298	No
15	POLD1	17847	2113	1.052	0.1330	No
16	NP	22027 9597 5273 5274	2199	1.000	0.1328	No
17	RRM1	18163	2409	0.847	0.1253	No
18	AK2	8563 2479 16073	2445	0.817	0.1270	No
19	NUDT2	16239	2714	0.615	0.1153	No
20	PDE5A	15431	2760	0.583	0.1154	No
21	GUCY1B3	15311	2870	0.519	0.1119	No
22	ENTPD5	4497	2918	0.495	0.1115	No
23	POLD4	12822	3141	0.386	0.1012	No
24	ADCY6	22139 2283 8551	3375	0.296	0.0899	No
25	AK1	4363	3821	0.186	0.0667	No
26	PDE4C	8481	3875	0.175	0.0646	No
27	GMPR2	2711	3887	0.172	0.0648	No
28	NME7	926 4101 14070 3986 3946 931	3955	0.161	0.0619	No
29	POLR2I	12839	4567	0.087	0.0292	No
30	PDE6G	20119	4645	0.082	0.0254	No
31	GUCY1A3	7216 12245 15310	4662	0.081	0.0249	No
32	PDE6H	17257	4777	0.074	0.0191	No
33	NPR2	16230	5181	0.057	-0.0025	No
34	PDE11A	10805	5379	0.050	-0.0129	No
35	ADCY5	10312	5390	0.050	-0.0132	No
36	AMPD3	4383 2110	5466	0.048	-0.0171	No
37	GDA	4764	6453	0.026	-0.0703	No
38	POLA1	24112	6832	0.019	-0.0906	No
39	PDE4D	10722 6235	6845	0.019	-0.0912	No
40	ENPP3	19803	6908	0.018	-0.0945	No
41	PDE9A	23301	6998	0.017	-0.0992	No
42	ADK	3302 3454 8555	7300	0.012	-0.1154	No
43	ENTPD1	4495	7360	0.012	-0.1186	No
44	PDE8B	5756	7427	0.011	-0.1221	No
45	PDE1A	9541 5234	7817	0.005	-0.1431	No
46	PKLR	1850 15545	7870	0.004	-0.1459	No
47	PDE1C	5235	8497	-0.004	-0.1798	No
48	GUCY2C	1140 16954	8573	-0.005	-0.1838	No
49	ENTPD3	19266	8933	-0.010	-0.2032	No
50	ITPA	9193	8996	-0.010	-0.2065	No
51	AK5	6042	9184	-0.013	-0.2165	No
52	GUCY2F	24045	9240	-0.013	-0.2195	No
53	ALLC	21093 2130	9332	-0.014	-0.2243	No
54	ADCY2	21412	9459	-0.016	-0.2311	No
55	POLR2B	16817	9561	-0.017	-0.2364	No
56	POLR3K	12447 7372	10060	-0.024	-0.2633	No
57	PDE7B	19807	10108	-0.025	-0.2657	No
58	NPR1	9480	10234	-0.026	-0.2723	No
59	PAPSS2	6258	10649	-0.033	-0.2946	No
60	POLE2	21053	10840	-0.036	-0.3047	No
61	POLR2C	9750	11135	-0.042	-0.3204	No
62	ENTPD2	8713	11290	-0.044	-0.3286	No
63	GUCY1A2	19580	11522	-0.049	-0.3408	No
64	AMPD2	1931 15197	11725	-0.054	-0.3515	No
65	AK3L1	8564	12166	-0.066	-0.3750	No
66	ENTPD8	12996	12216	-0.067	-0.3774	No
67	ADCY3	21329 894	12389	-0.072	-0.3864	No
68	AMPD1	5051	12460	-0.074	-0.3898	No
69	RRM2B	6902 6903 11801	12478	-0.075	-0.3904	No
70	ADCY8	22281	12773	-0.085	-0.4059	No
71	ADCY4	2980 21818	12821	-0.087	-0.4081	No
72	NT5C1B	21315	13461	-0.120	-0.4421	No
73	CANT1	13304	13957	-0.160	-0.4682	No
74	ADSSL1	21136 2087	14144	-0.179	-0.4774	No
75	ENTPD6	4496 2678	14502	-0.225	-0.4957	No
76	PDE4A	3037 19542 3083 3023	14639	-0.247	-0.5020	No
77	ENPP1	19804	14644	-0.248	-0.5011	No
78	PDE10A	23387	15049	-0.333	-0.5215	No
79	PDE8A	18202	15186	-0.374	-0.5272	No
80	POLD3	17742	15292	-0.408	-0.5310	No
81	NT5E	19360 18702	15361	-0.428	-0.5328	No
82	NME4	23065 1577	15373	-0.432	-0.5315	No
83	PKM2	3642 9573	15517	-0.490	-0.5370	No
84	PNPT1	20936	15541	-0.503	-0.5361	No
85	NT5C3	17136	15775	-0.616	-0.5459	No
86	POLE4	12441	15943	-0.724	-0.5517	No
87	POLR2A	5394	16021	-0.780	-0.5524	No
88	POLR1A	9749 5393	16138	-0.877	-0.5548	No
89	HPRT1	2655 24339 408	16256	-0.971	-0.5568	No
90	POLR1D	3593 3658 16623	16315	-1.000	-0.5555	No
91	ECGF1	22160	16512	-1.147	-0.5610	No
92	PRPS1	24233	16633	-1.283	-0.5618	No
93	PAICS	16820	16646	-1.295	-0.5567	No
94	ADCY7	8552 448	17062	-1.765	-0.5712	Yes
95	POLR2K	9413	17076	-1.786	-0.5640	Yes
96	POLR2E	3325 19699	17108	-1.814	-0.5576	Yes
97	PDE7A	9544 1788	17134	-1.859	-0.5507	Yes
98	POLR2G	23753	17143	-1.872	-0.5428	Yes
99	PRPS2	24003	17180	-1.924	-0.5362	Yes
100	POLR3A	21900	17377	-2.234	-0.5368	Yes
101	POLR3H	13460 8135	17517	-2.467	-0.5334	Yes
102	FHIT	21920	17582	-2.592	-0.5253	Yes
103	PRIM1	19847	17631	-2.714	-0.5158	Yes
104	POLR2J	16672	17714	-2.890	-0.5074	Yes
105	ENTPD4	7449	17716	-2.897	-0.4946	Yes
106	GART	22543 1754	17782	-3.046	-0.4845	Yes
107	NME6	3139 19297	17843	-3.167	-0.4737	Yes
108	NT5M	8345 4175	17914	-3.392	-0.4624	Yes
109	GMPS	15578	17940	-3.465	-0.4483	Yes
110	RFC5	13005 7791	18005	-3.668	-0.4355	Yes
111	POLE3	7200	18084	-3.862	-0.4225	Yes
112	POLE	16755	18111	-3.955	-0.4063	Yes
113	NUDT9	7897	18179	-4.225	-0.3911	Yes
114	POLA2	23988	18195	-4.278	-0.3729	Yes
115	NUDT5	15121	18243	-4.469	-0.3556	Yes
116	ADSL	4358	18263	-4.560	-0.3363	Yes
117	POLR2H	10888	18316	-4.847	-0.3176	Yes
118	NT5C	20151	18338	-5.003	-0.2964	Yes
119	IMPDH2	10730	18367	-5.139	-0.2751	Yes
120	ATIC	14231 3968	18414	-5.446	-0.2533	Yes
121	POLD2	20537	18438	-5.603	-0.2296	Yes
122	GUK1	20432	18445	-5.712	-0.2046	Yes
123	APRT	8620	18478	-6.037	-0.1794	Yes
124	NME2	9468	18508	-6.307	-0.1529	Yes
125	POLR3B	12875	18537	-6.688	-0.1247	Yes
126	PPAT	6081	18539	-6.711	-0.0949	Yes
127	NME1	9467	18540	-6.712	-0.0650	Yes
128	PDE6D	13897 3945	18543	-6.772	-0.0350	Yes
129	POLR1B	14857	18598	-8.740	0.0010	Yes