Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_LMproB.phenotype_transDMproB_versus_LMproB.cls #transDMproB_versus_LMproB |
| Phenotype | phenotype_transDMproB_versus_LMproB.cls#transDMproB_versus_LMproB |
| Upregulated in class | LMproB |
| GeneSet | DOUBLE_STRANDED_DNA_BINDING |
| Enrichment Score (ES) | -0.67325467 |
| Normalized Enrichment Score (NES) | -1.5057843 |
| Nominal p-value | 0.033254158 |
| FDR q-value | 0.6185945 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CGGBP1 | 22724 | 323 | 2.000 | 0.0448 | No | ||
| 2 | MSH6 | 23137 5120 | 380 | 1.889 | 0.1006 | No | ||
| 3 | SMAD2 | 23511 | 864 | 1.376 | 0.1174 | No | ||
| 4 | FEN1 | 8961 | 2585 | 0.433 | 0.0383 | No | ||
| 5 | MSH3 | 5119 | 2956 | 0.321 | 0.0284 | No | ||
| 6 | APTX | 2455 7291 | 3114 | 0.283 | 0.0287 | No | ||
| 7 | SATB1 | 5408 | 3397 | 0.230 | 0.0207 | No | ||
| 8 | HNRPDL | 11947 3551 6954 | 3730 | 0.185 | 0.0086 | No | ||
| 9 | RAD51 | 2897 14903 | 5880 | 0.057 | -0.1053 | No | ||
| 10 | HMGB2 | 13594 | 6290 | 0.047 | -0.1258 | No | ||
| 11 | XRCC5 | 14229 | 7184 | 0.032 | -0.1729 | No | ||
| 12 | TERF1 | 14293 | 7215 | 0.031 | -0.1735 | No | ||
| 13 | HLF | 10124 | 7395 | 0.028 | -0.1823 | No | ||
| 14 | PMS2 | 16632 | 11592 | -0.020 | -0.4074 | No | ||
| 15 | IFI16 | 13745 | 13274 | -0.046 | -0.4964 | No | ||
| 16 | PURA | 9670 | 14274 | -0.073 | -0.5479 | No | ||
| 17 | MSH2 | 23138 | 16605 | -0.441 | -0.6595 | Yes | ||
| 18 | RBMS1 | 14580 | 16721 | -0.499 | -0.6502 | Yes | ||
| 19 | NTHL1 | 23357 | 17063 | -0.685 | -0.6473 | Yes | ||
| 20 | MRE11A | 3014 19560 | 17156 | -0.746 | -0.6290 | Yes | ||
| 21 | KIN | 15120 | 17528 | -1.017 | -0.6173 | Yes | ||
| 22 | MTERF | 9911 | 17533 | -1.020 | -0.5858 | Yes | ||
| 23 | PNKP | 4052 18258 | 17540 | -1.028 | -0.5542 | Yes | ||
| 24 | XRCC6 | 2286 8991 | 17660 | -1.136 | -0.5253 | Yes | ||
| 25 | CSDA | 1163 16966 1134 | 17927 | -1.415 | -0.4955 | Yes | ||
| 26 | RAD51AP1 | 5350 1073 | 18117 | -1.643 | -0.4546 | Yes | ||
| 27 | YBX1 | 5929 2389 | 18178 | -1.746 | -0.4035 | Yes | ||
| 28 | ZNF638 | 9476 | 18282 | -1.954 | -0.3483 | Yes | ||
| 29 | MLH1 | 18982 | 18301 | -2.002 | -0.2870 | Yes | ||
| 30 | ERCC5 | 14255 4097 | 18568 | -3.343 | -0.1973 | Yes | ||
| 31 | TP53 | 20822 | 18610 | -6.426 | 0.0003 | Yes |
