Dataset | Set_04_transDMproB_versus_LMproB.phenotype_transDMproB_versus_LMproB.cls #transDMproB_versus_LMproB |
Phenotype | phenotype_transDMproB_versus_LMproB.cls#transDMproB_versus_LMproB |
Upregulated in class | LMproB |
GeneSet | V$NRF1_Q6 |
Enrichment Score (ES) | -0.51024187 |
Normalized Enrichment Score (NES) | -1.4223934 |
Nominal p-value | 0.010928961 |
FDR q-value | 0.60516465 |
FWER p-Value | 0.981 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | COX7A2L | 9819 | 214 | 2.226 | 0.0107 | No | ||
2 | RAB10 | 2090 21119 | 303 | 2.030 | 0.0262 | No | ||
3 | SMAD5 | 21621 | 469 | 1.756 | 0.0349 | No | ||
4 | HNRPH1 | 12222 1486 1220 7202 7201 | 597 | 1.629 | 0.0443 | No | ||
5 | SFRS7 | 22889 | 625 | 1.605 | 0.0589 | No | ||
6 | YWHAE | 20776 | 651 | 1.581 | 0.0733 | No | ||
7 | CFL1 | 4516 | 1016 | 1.253 | 0.0662 | No | ||
8 | ATP6V1D | 7872 | 1021 | 1.251 | 0.0785 | No | ||
9 | NDUFB8 | 7418 | 1159 | 1.161 | 0.0827 | No | ||
10 | HNRPL | 18315 | 1161 | 1.161 | 0.0942 | No | ||
11 | SRRM1 | 6958 | 1330 | 1.040 | 0.0955 | No | ||
12 | ENDOGL1 | 3115 19275 | 1366 | 1.016 | 0.1038 | No | ||
13 | SRR | 6566 11328 | 1529 | 0.956 | 0.1046 | No | ||
14 | E2F6 | 6925 6926 11920 | 1611 | 0.912 | 0.1093 | No | ||
15 | FUT8 | 2163 21233 | 1625 | 0.903 | 0.1176 | No | ||
16 | PRKRIR | 7834 | 1655 | 0.889 | 0.1250 | No | ||
17 | MRPL22 | 10111 | 1795 | 0.805 | 0.1255 | No | ||
18 | GPSN2 | 18823 3868 | 1819 | 0.791 | 0.1322 | No | ||
19 | COG6 | 15345 | 1876 | 0.760 | 0.1367 | No | ||
20 | FNBP4 | 14956 2671 | 1897 | 0.747 | 0.1431 | No | ||
21 | VAT1 | 11253 | 1947 | 0.723 | 0.1477 | No | ||
22 | PSMA4 | 11179 | 2022 | 0.681 | 0.1505 | No | ||
23 | BCKDHA | 17925 | 2027 | 0.678 | 0.1571 | No | ||
24 | PPP1R15B | 4254 14135 | 2116 | 0.637 | 0.1587 | No | ||
25 | EXOSC5 | 18334 | 2343 | 0.524 | 0.1517 | No | ||
26 | SUFU | 6283 | 2627 | 0.423 | 0.1406 | No | ||
27 | MAPT | 9420 1347 | 2867 | 0.346 | 0.1311 | No | ||
28 | ARFGAP3 | 22183 | 2892 | 0.340 | 0.1332 | No | ||
29 | SEC24C | 22086 | 2910 | 0.335 | 0.1356 | No | ||
30 | THEM2 | 21512 | 2990 | 0.312 | 0.1345 | No | ||
31 | POU2F1 | 5275 3989 4065 4010 | 3105 | 0.284 | 0.1311 | No | ||
32 | CCNI | 4493 | 3156 | 0.276 | 0.1312 | No | ||
33 | RNF111 | 13555 8218 13556 | 3192 | 0.267 | 0.1320 | No | ||
34 | SFRS1 | 8492 | 3253 | 0.256 | 0.1313 | No | ||
35 | HIP2 | 3626 3485 16838 | 3261 | 0.254 | 0.1334 | No | ||
36 | JMJD2C | 16188 | 3515 | 0.212 | 0.1219 | No | ||
37 | MAZ | 1327 17623 | 3581 | 0.201 | 0.1204 | No | ||
38 | ACCN2 | 22363 | 3673 | 0.191 | 0.1173 | No | ||
39 | MAP4K1 | 18313 | 3796 | 0.177 | 0.1125 | No | ||
40 | BCL7A | 8063 | 3946 | 0.156 | 0.1060 | No | ||
41 | DNAJA1 | 4878 16242 2345 | 4080 | 0.144 | 0.1002 | No | ||
42 | U2AF2 | 5813 5812 5814 | 4089 | 0.143 | 0.1012 | No | ||
43 | HOXC6 | 22339 2302 | 4655 | 0.103 | 0.0717 | No | ||
44 | HMMR | 20493 1243 | 4697 | 0.100 | 0.0705 | No | ||
45 | SYNGR4 | 17825 | 4917 | 0.089 | 0.0595 | No | ||
46 | PACRG | 23127 | 6592 | 0.042 | -0.0307 | No | ||
47 | CKS2 | 7264 | 6862 | 0.037 | -0.0449 | No | ||
48 | POU4F2 | 9603 5276 | 7003 | 0.034 | -0.0521 | No | ||
49 | POP7 | 16329 | 7166 | 0.032 | -0.0606 | No | ||
50 | JAG1 | 14415 | 7242 | 0.031 | -0.0643 | No | ||
51 | RHOA | 8624 4409 4410 | 7462 | 0.027 | -0.0759 | No | ||
52 | STX12 | 4140 | 7625 | 0.025 | -0.0845 | No | ||
53 | DNAJC3 | 21934 | 8431 | 0.015 | -0.1279 | No | ||
54 | ADAM10 | 4336 | 8519 | 0.014 | -0.1325 | No | ||
55 | MST1 | 9089 | 8583 | 0.013 | -0.1357 | No | ||
56 | GABRB2 | 20922 | 8978 | 0.009 | -0.1570 | No | ||
57 | DISP2 | 5652 | 9029 | 0.008 | -0.1596 | No | ||
58 | MCRS1 | 6961 6960 6962 | 9031 | 0.008 | -0.1596 | No | ||
59 | USF2 | 10262 5833 10263 | 9417 | 0.004 | -0.1804 | No | ||
60 | FGF12 | 1723 22621 | 9778 | 0.000 | -0.1999 | No | ||
61 | WNT5A | 22066 5880 | 10414 | -0.007 | -0.2342 | No | ||
62 | GRIN2B | 16957 | 10421 | -0.007 | -0.2344 | No | ||
63 | PHC3 | 6313 | 10451 | -0.007 | -0.2359 | No | ||
64 | JARID1C | 5460 2563 | 11180 | -0.015 | -0.2752 | No | ||
65 | AIP | 23955 | 11362 | -0.017 | -0.2848 | No | ||
66 | MAP2K7 | 6453 | 11439 | -0.018 | -0.2888 | No | ||
67 | PAQR4 | 23105 | 11508 | -0.019 | -0.2922 | No | ||
68 | EIF2S1 | 4658 | 11931 | -0.024 | -0.3149 | No | ||
69 | NNAT | 2764 5180 | 11959 | -0.025 | -0.3161 | No | ||
70 | PTPN2 | 23414 | 12047 | -0.026 | -0.3205 | No | ||
71 | UXS1 | 13965 | 12131 | -0.027 | -0.3247 | No | ||
72 | FMR1 | 24321 | 12334 | -0.030 | -0.3354 | No | ||
73 | ABI2 | 4037 6830 | 12374 | -0.030 | -0.3372 | No | ||
74 | VAV3 | 1774 1848 15443 | 12444 | -0.031 | -0.3406 | No | ||
75 | TTRAP | 21692 | 12575 | -0.033 | -0.3473 | No | ||
76 | LRP1 | 9284 | 12843 | -0.038 | -0.3614 | No | ||
77 | MLLT7 | 24278 | 13035 | -0.042 | -0.3713 | No | ||
78 | GABRB1 | 16832 | 13160 | -0.044 | -0.3776 | No | ||
79 | PHF1 | 23324 1551 | 13321 | -0.047 | -0.3858 | No | ||
80 | RQCD1 | 12205 | 13516 | -0.051 | -0.3958 | No | ||
81 | PARK2 | 6944 11939 1499 23385 | 14312 | -0.074 | -0.4381 | No | ||
82 | MPP5 | 21230 7078 | 14485 | -0.081 | -0.4466 | No | ||
83 | CLOCK | 8749 16507 4530 | 14631 | -0.087 | -0.4536 | No | ||
84 | POLH | 22966 | 14657 | -0.089 | -0.4540 | No | ||
85 | NFYA | 5172 | 14792 | -0.096 | -0.4603 | No | ||
86 | SPRY4 | 23448 | 14931 | -0.106 | -0.4667 | No | ||
87 | SPATA5L1 | 10062 | 14932 | -0.106 | -0.4657 | No | ||
88 | FGFR1OP2 | 12544 12543 7457 | 14988 | -0.109 | -0.4676 | No | ||
89 | AFG3L1 | 8547 4342 18427 3865 | 15047 | -0.115 | -0.4696 | No | ||
90 | CNTNAP1 | 11987 | 15187 | -0.126 | -0.4758 | No | ||
91 | ARRB2 | 20806 | 15284 | -0.135 | -0.4797 | No | ||
92 | SNX12 | 7061 | 15330 | -0.139 | -0.4807 | No | ||
93 | MRPL45 | 20680 | 15436 | -0.151 | -0.4849 | No | ||
94 | MRPS18B | 7365 | 15494 | -0.158 | -0.4864 | No | ||
95 | NF1 | 5165 | 15563 | -0.167 | -0.4884 | No | ||
96 | HOXC4 | 4864 | 15741 | -0.198 | -0.4960 | No | ||
97 | SEC14L1 | 1212 20583 | 15749 | -0.199 | -0.4944 | No | ||
98 | XPO5 | 7802 | 15757 | -0.201 | -0.4928 | No | ||
99 | CRK | 4559 1249 | 15815 | -0.212 | -0.4937 | No | ||
100 | KCNK5 | 4946 9212 | 15977 | -0.247 | -0.5000 | No | ||
101 | PDE7A | 9544 1788 | 16023 | -0.257 | -0.4999 | No | ||
102 | ALG8 | 11779 3912 2277 | 16105 | -0.278 | -0.5015 | No | ||
103 | TTLL4 | 328 | 16114 | -0.280 | -0.4991 | No | ||
104 | SLC39A7 | 23022 | 16238 | -0.315 | -0.5026 | Yes | ||
105 | RAGE | 6465 2056 2165 | 16250 | -0.319 | -0.5000 | Yes | ||
106 | SPINT2 | 4128 17899 | 16291 | -0.331 | -0.4989 | Yes | ||
107 | USP37 | 13923 | 16324 | -0.341 | -0.4972 | Yes | ||
108 | MPDU1 | 20386 | 16491 | -0.405 | -0.5021 | Yes | ||
109 | DDIT3 | 19857 | 16560 | -0.426 | -0.5015 | Yes | ||
110 | CBFB | 3769 18499 | 16572 | -0.429 | -0.4978 | Yes | ||
111 | BTBD3 | 10457 2975 6007 6006 | 16684 | -0.477 | -0.4991 | Yes | ||
112 | MECP2 | 5088 | 16772 | -0.524 | -0.4985 | Yes | ||
113 | MAGED2 | 24034 | 16785 | -0.528 | -0.4939 | Yes | ||
114 | MIB1 | 5908 | 17009 | -0.652 | -0.4995 | Yes | ||
115 | ZNHIT1 | 16334 | 17209 | -0.792 | -0.5023 | Yes | ||
116 | SHMT2 | 3307 19601 | 17288 | -0.852 | -0.4980 | Yes | ||
117 | PPP1R12A | 3354 19886 | 17337 | -0.897 | -0.4916 | Yes | ||
118 | VDP | 16794 | 17375 | -0.920 | -0.4844 | Yes | ||
119 | SPOP | 5498 | 17466 | -0.989 | -0.4794 | Yes | ||
120 | TRIM28 | 18389 | 17467 | -0.989 | -0.4695 | Yes | ||
121 | CCT3 | 8709 | 17535 | -1.024 | -0.4629 | Yes | ||
122 | SFRS9 | 16731 | 17581 | -1.059 | -0.4548 | Yes | ||
123 | PPP1R10 | 6972 11960 6971 | 17590 | -1.065 | -0.4445 | Yes | ||
124 | GOLGA1 | 14595 | 17696 | -1.180 | -0.4384 | Yes | ||
125 | XRCC1 | 173 | 17697 | -1.180 | -0.4266 | Yes | ||
126 | NEK8 | 20338 | 17812 | -1.294 | -0.4199 | Yes | ||
127 | BAT3 | 5896 | 17892 | -1.368 | -0.4104 | Yes | ||
128 | HIBADH | 17144 | 17956 | -1.452 | -0.3993 | Yes | ||
129 | SSBP4 | 13368 | 18012 | -1.531 | -0.3870 | Yes | ||
130 | TCTA | 4167 | 18063 | -1.581 | -0.3739 | Yes | ||
131 | RAB18 | 1972 5342 | 18079 | -1.596 | -0.3587 | Yes | ||
132 | ACTR1A | 23653 | 18088 | -1.610 | -0.3431 | Yes | ||
133 | PREB | 6948 3628 | 18119 | -1.645 | -0.3282 | Yes | ||
134 | FUS | 6135 | 18152 | -1.696 | -0.3130 | Yes | ||
135 | EIF5A | 11345 20379 6590 | 18169 | -1.721 | -0.2967 | Yes | ||
136 | TRIM39 | 22994 | 18177 | -1.734 | -0.2797 | Yes | ||
137 | POLA2 | 23988 | 18327 | -2.076 | -0.2670 | Yes | ||
138 | PCTK1 | 24369 | 18357 | -2.140 | -0.2472 | Yes | ||
139 | DNMT1 | 19217 | 18396 | -2.214 | -0.2271 | Yes | ||
140 | GTF2F1 | 13599 | 18443 | -2.376 | -0.2058 | Yes | ||
141 | SNRP70 | 1186 | 18469 | -2.504 | -0.1821 | Yes | ||
142 | RXRB | 23285 9768 | 18477 | -2.529 | -0.1572 | Yes | ||
143 | TUBG1 | 20662 | 18526 | -2.867 | -0.1311 | Yes | ||
144 | MAGED1 | 24108 | 18534 | -2.940 | -0.1021 | Yes | ||
145 | PLOD3 | 16666 | 18548 | -3.107 | -0.0717 | Yes | ||
146 | CLGN | 4528 | 18613 | -7.532 | 0.0002 | Yes |