Dataset | Set_04_transDMproB_versus_LMproB.phenotype_transDMproB_versus_LMproB.cls #transDMproB_versus_LMproB |
Phenotype | phenotype_transDMproB_versus_LMproB.cls#transDMproB_versus_LMproB |
Upregulated in class | transDMproB |
GeneSet | V$NF1_Q6_01 |
Enrichment Score (ES) | 0.5037422 |
Normalized Enrichment Score (NES) | 1.3477575 |
Nominal p-value | 0.012598425 |
FDR q-value | 0.9669042 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MGST1 | 17254 | 91 | 2.787 | 0.0392 | Yes | ||
2 | ATP6V1A | 8638 | 142 | 2.504 | 0.0761 | Yes | ||
3 | UBE2D3 | 7253 | 153 | 2.446 | 0.1143 | Yes | ||
4 | AXUD1 | 18967 | 204 | 2.257 | 0.1474 | Yes | ||
5 | H1F0 | 22428 | 247 | 2.149 | 0.1791 | Yes | ||
6 | ORMDL3 | 12386 | 249 | 2.141 | 0.2130 | Yes | ||
7 | LGALS9 | 1441 20332 1200 | 299 | 2.034 | 0.2425 | Yes | ||
8 | MBNL2 | 21932 | 305 | 2.027 | 0.2743 | Yes | ||
9 | NFKBIA | 21065 | 308 | 2.021 | 0.3062 | Yes | ||
10 | HMGN2 | 9095 | 481 | 1.743 | 0.3245 | Yes | ||
11 | ZNF148 | 5949 | 540 | 1.670 | 0.3478 | Yes | ||
12 | RRAS | 18256 | 694 | 1.536 | 0.3638 | Yes | ||
13 | POLR2H | 10888 | 779 | 1.450 | 0.3822 | Yes | ||
14 | NACA | 9444 5147 | 914 | 1.328 | 0.3960 | Yes | ||
15 | PPM1D | 20721 | 956 | 1.299 | 0.4143 | Yes | ||
16 | PGF | 21020 | 1054 | 1.230 | 0.4285 | Yes | ||
17 | SOX4 | 5479 | 1064 | 1.224 | 0.4474 | Yes | ||
18 | RAPGEF5 | 5739 10155 21123 | 1138 | 1.176 | 0.4621 | Yes | ||
19 | ENPP1 | 19804 | 1450 | 0.990 | 0.4609 | Yes | ||
20 | KLF13 | 17807 | 1511 | 0.964 | 0.4729 | Yes | ||
21 | NDUFS2 | 4089 13760 | 1905 | 0.742 | 0.4634 | Yes | ||
22 | COPG2 | 17193 | 1949 | 0.720 | 0.4724 | Yes | ||
23 | H1FX | 10835 | 2107 | 0.643 | 0.4741 | Yes | ||
24 | MGAT4A | 13977 | 2139 | 0.622 | 0.4823 | Yes | ||
25 | JDP2 | 21201 | 2157 | 0.612 | 0.4910 | Yes | ||
26 | STARD3 | 20675 | 2214 | 0.576 | 0.4971 | Yes | ||
27 | JUP | 4937 | 2256 | 0.557 | 0.5037 | Yes | ||
28 | EFNB1 | 24285 | 2651 | 0.413 | 0.4889 | No | ||
29 | ARCN1 | 19143 | 2834 | 0.354 | 0.4847 | No | ||
30 | CACNA2D1 | 8676 | 2921 | 0.333 | 0.4853 | No | ||
31 | EIF4G2 | 1908 8892 | 2927 | 0.331 | 0.4902 | No | ||
32 | NFIA | 16172 5170 | 3250 | 0.257 | 0.4768 | No | ||
33 | PTMA | 9657 | 3303 | 0.245 | 0.4779 | No | ||
34 | CLDN10 | 21935 2785 2601 2720 7188 | 3492 | 0.215 | 0.4711 | No | ||
35 | XPR1 | 5383 | 3827 | 0.172 | 0.4557 | No | ||
36 | ZBTB5 | 15891 | 3834 | 0.171 | 0.4581 | No | ||
37 | KRTCAP2 | 15541 | 3841 | 0.170 | 0.4605 | No | ||
38 | BCAR3 | 15432 | 4253 | 0.127 | 0.4402 | No | ||
39 | TANK | 2839 15006 2729 | 4279 | 0.126 | 0.4408 | No | ||
40 | RASGRP2 | 9693 | 4343 | 0.120 | 0.4393 | No | ||
41 | NOL4 | 2028 11432 | 4495 | 0.112 | 0.4329 | No | ||
42 | STAT3 | 5525 9906 | 4604 | 0.106 | 0.4287 | No | ||
43 | MCAM | 3109 19479 | 4634 | 0.104 | 0.4288 | No | ||
44 | GCM1 | 19372 | 4827 | 0.093 | 0.4199 | No | ||
45 | GPR158 | 149 | 5116 | 0.081 | 0.4055 | No | ||
46 | LOX | 23438 | 5160 | 0.079 | 0.4044 | No | ||
47 | STAT5B | 20222 | 5176 | 0.079 | 0.4049 | No | ||
48 | POSTN | 1801 11927 | 5184 | 0.078 | 0.4057 | No | ||
49 | IRS4 | 9183 4926 | 5214 | 0.077 | 0.4054 | No | ||
50 | SPRY1 | 15606 1901 | 5222 | 0.077 | 0.4062 | No | ||
51 | NR1H3 | 10258 2787 | 5262 | 0.075 | 0.4053 | No | ||
52 | RBP2 | 19347 | 5335 | 0.073 | 0.4026 | No | ||
53 | EPHB2 | 4675 2440 8910 | 5439 | 0.070 | 0.3981 | No | ||
54 | SV2A | 15498 12250 | 5528 | 0.067 | 0.3944 | No | ||
55 | APLN | 24164 | 5579 | 0.065 | 0.3927 | No | ||
56 | GDPD2 | 24280 | 5623 | 0.064 | 0.3914 | No | ||
57 | YARS | 16071 | 5723 | 0.061 | 0.3870 | No | ||
58 | ALK | 8574 | 5729 | 0.061 | 0.3877 | No | ||
59 | EXTL3 | 21785 21786 3088 | 5736 | 0.061 | 0.3883 | No | ||
60 | DCT | 4603 21723 | 5920 | 0.056 | 0.3793 | No | ||
61 | RHOQ | 23142 | 5981 | 0.054 | 0.3769 | No | ||
62 | CNTNAP4 | 18462 3857 | 6063 | 0.053 | 0.3733 | No | ||
63 | SYT8 | 18006 | 6412 | 0.045 | 0.3552 | No | ||
64 | SPINK5 | 23569 | 6887 | 0.036 | 0.3301 | No | ||
65 | TREX2 | 24137 | 7071 | 0.033 | 0.3207 | No | ||
66 | CHGA | 21178 2151 | 7102 | 0.033 | 0.3195 | No | ||
67 | TGIF2 | 6013 6012 | 7124 | 0.033 | 0.3189 | No | ||
68 | H3F3B | 4839 | 7177 | 0.032 | 0.3166 | No | ||
69 | EBF2 | 21975 | 7283 | 0.030 | 0.3114 | No | ||
70 | SYTL2 | 18190 1539 3730 | 7344 | 0.029 | 0.3086 | No | ||
71 | MOV10 | 9403 9402 5114 | 7488 | 0.027 | 0.3013 | No | ||
72 | MPP2 | 20209 | 7593 | 0.025 | 0.2960 | No | ||
73 | TYR | 17763 | 7702 | 0.024 | 0.2905 | No | ||
74 | SOX2 | 9849 15612 | 7804 | 0.023 | 0.2854 | No | ||
75 | SLC26A7 | 5538 2372 | 7828 | 0.022 | 0.2845 | No | ||
76 | GJA3 | 21807 | 8018 | 0.019 | 0.2746 | No | ||
77 | SLITRK6 | 21724 | 8165 | 0.018 | 0.2670 | No | ||
78 | PAX3 | 13910 | 8195 | 0.017 | 0.2657 | No | ||
79 | ZIC5 | 12268 | 8209 | 0.017 | 0.2652 | No | ||
80 | NTNG2 | 2731 9330 | 8428 | 0.015 | 0.2536 | No | ||
81 | CYP1A2 | 19097 | 8606 | 0.013 | 0.2442 | No | ||
82 | PIPOX | 20340 | 8616 | 0.013 | 0.2439 | No | ||
83 | MTSS1 | 5585 22285 | 8675 | 0.012 | 0.2410 | No | ||
84 | IL2RA | 4918 | 8760 | 0.011 | 0.2366 | No | ||
85 | HBP1 | 2048 2162 21086 | 8762 | 0.011 | 0.2367 | No | ||
86 | NOX3 | 10322 | 8798 | 0.011 | 0.2350 | No | ||
87 | SP7 | 22110 | 9017 | 0.008 | 0.2233 | No | ||
88 | SLC24A4 | 6223 | 9190 | 0.006 | 0.2141 | No | ||
89 | ATP8B3 | 12513 7426 19693 | 9206 | 0.006 | 0.2134 | No | ||
90 | CACNB1 | 1443 1304 | 9319 | 0.005 | 0.2074 | No | ||
91 | SLC2A4 | 20380 | 9411 | 0.004 | 0.2025 | No | ||
92 | ASPN | 21644 | 9423 | 0.004 | 0.2020 | No | ||
93 | DLX3 | 20697 | 9535 | 0.003 | 0.1960 | No | ||
94 | LOXL1 | 5002 | 9779 | 0.000 | 0.1828 | No | ||
95 | RPE65 | 15382 | 9801 | -0.000 | 0.1817 | No | ||
96 | BMP6 | 8659 | 9809 | -0.000 | 0.1813 | No | ||
97 | B2M | 72 14882 | 9955 | -0.002 | 0.1735 | No | ||
98 | B3GALT2 | 6498 | 10027 | -0.003 | 0.1697 | No | ||
99 | NFATC3 | 5169 | 10340 | -0.006 | 0.1529 | No | ||
100 | KCNH2 | 16592 | 10525 | -0.008 | 0.1430 | No | ||
101 | SALL1 | 18796 12207 | 10682 | -0.009 | 0.1347 | No | ||
102 | GDF8 | 9411 | 10722 | -0.010 | 0.1327 | No | ||
103 | BBOX1 | 5010 9290 | 10963 | -0.013 | 0.1199 | No | ||
104 | SMARCA1 | 24165 | 10997 | -0.013 | 0.1183 | No | ||
105 | GSH1 | 16622 | 11115 | -0.014 | 0.1122 | No | ||
106 | CROT | 13165 | 11156 | -0.015 | 0.1103 | No | ||
107 | TRERF1 | 1546 23213 | 11184 | -0.015 | 0.1091 | No | ||
108 | TRIM46 | 1779 15281 | 11307 | -0.016 | 0.1027 | No | ||
109 | TEK | 16175 | 11409 | -0.018 | 0.0975 | No | ||
110 | SULT2A1 | 5527 | 11449 | -0.018 | 0.0957 | No | ||
111 | COL11A2 | 23286 | 11498 | -0.019 | 0.0934 | No | ||
112 | RARB | 3011 21915 | 11533 | -0.019 | 0.0918 | No | ||
113 | SLC2A12 | 20073 | 11754 | -0.022 | 0.0803 | No | ||
114 | PROP1 | 20472 | 11794 | -0.023 | 0.0785 | No | ||
115 | SCUBE2 | 1879 17678 | 11925 | -0.024 | 0.0719 | No | ||
116 | LGR6 | 11623 977 | 11994 | -0.025 | 0.0686 | No | ||
117 | FGF4 | 8964 | 12074 | -0.026 | 0.0647 | No | ||
118 | RBM9 | 2276 13528 | 12175 | -0.027 | 0.0597 | No | ||
119 | HOXA6 | 17150 | 12179 | -0.028 | 0.0600 | No | ||
120 | LRRTM1 | 17408 | 12355 | -0.030 | 0.0510 | No | ||
121 | ADAMTSL1 | 16181 | 12382 | -0.030 | 0.0500 | No | ||
122 | SFRP2 | 15564 | 12400 | -0.031 | 0.0496 | No | ||
123 | MID1 | 5097 5098 | 12534 | -0.033 | 0.0429 | No | ||
124 | WNT16 | 17512 1152 | 12580 | -0.033 | 0.0410 | No | ||
125 | DUSP14 | 12124 | 12609 | -0.034 | 0.0400 | No | ||
126 | KIRREL2 | 17889 3922 | 12719 | -0.036 | 0.0347 | No | ||
127 | STMN4 | 21977 | 12916 | -0.039 | 0.0246 | No | ||
128 | HIPK1 | 4851 | 12922 | -0.039 | 0.0250 | No | ||
129 | NLGN3 | 10878 | 12933 | -0.039 | 0.0251 | No | ||
130 | HIP1 | 5676 | 13259 | -0.046 | 0.0082 | No | ||
131 | FGF11 | 20383 | 13298 | -0.046 | 0.0069 | No | ||
132 | CITED2 | 5118 14477 | 13366 | -0.048 | 0.0040 | No | ||
133 | SESN3 | 19561 | 13384 | -0.048 | 0.0038 | No | ||
134 | MKL1 | 5864 | 13446 | -0.050 | 0.0013 | No | ||
135 | JPH1 | 13994 | 13771 | -0.058 | -0.0154 | No | ||
136 | JPH4 | 21826 | 13774 | -0.058 | -0.0146 | No | ||
137 | TLX3 | 20501 | 13811 | -0.059 | -0.0156 | No | ||
138 | SMAD6 | 19083 | 14205 | -0.071 | -0.0358 | No | ||
139 | DNAJB4 | 12451 1916 1832 | 14368 | -0.077 | -0.0433 | No | ||
140 | NCALD | 22310 | 14437 | -0.079 | -0.0458 | No | ||
141 | ALDOC | 20759 311 | 14620 | -0.087 | -0.0543 | No | ||
142 | ATF4 | 22417 2239 | 14672 | -0.090 | -0.0556 | No | ||
143 | MAP4K5 | 11853 21048 2101 2142 | 14713 | -0.091 | -0.0563 | No | ||
144 | TSLP | 23604 1955 | 14902 | -0.103 | -0.0649 | No | ||
145 | SEMA4C | 9799 | 14907 | -0.104 | -0.0635 | No | ||
146 | DUSP10 | 4003 14016 | 14915 | -0.104 | -0.0622 | No | ||
147 | PPP2CA | 20890 | 15002 | -0.111 | -0.0651 | No | ||
148 | PTHR1 | 5318 18985 | 15004 | -0.111 | -0.0634 | No | ||
149 | CYP26B1 | 17093 | 15028 | -0.113 | -0.0629 | No | ||
150 | KLHL2 | 13381 | 15033 | -0.113 | -0.0613 | No | ||
151 | FIGF | 24212 | 15320 | -0.139 | -0.0746 | No | ||
152 | MAMDC1 | 21054 6798 | 15323 | -0.139 | -0.0725 | No | ||
153 | HOXB5 | 20687 | 15386 | -0.145 | -0.0736 | No | ||
154 | IGSF8 | 14048 | 15415 | -0.149 | -0.0727 | No | ||
155 | RETNLB | 12178 | 15431 | -0.150 | -0.0712 | No | ||
156 | TLK2 | 20628 | 15521 | -0.160 | -0.0735 | No | ||
157 | DDIT4L | 15410 | 15682 | -0.186 | -0.0792 | No | ||
158 | PTGDS | 14658 | 15795 | -0.208 | -0.0820 | No | ||
159 | BCL9 | 15232 | 15819 | -0.213 | -0.0798 | No | ||
160 | RHOJ | 21241 | 16029 | -0.259 | -0.0871 | No | ||
161 | SNF1LK | 23033 | 16175 | -0.297 | -0.0902 | No | ||
162 | ACVR1 | 4334 | 16280 | -0.327 | -0.0907 | No | ||
163 | CLCN2 | 22637 | 16288 | -0.330 | -0.0858 | No | ||
164 | LAMB2 | 9265 | 16331 | -0.344 | -0.0827 | No | ||
165 | RNF41 | 12553 7464 | 16374 | -0.362 | -0.0792 | No | ||
166 | RNF25 | 13922 3929 | 16468 | -0.395 | -0.0780 | No | ||
167 | RUNX1 | 4481 | 17175 | -0.761 | -0.1042 | No | ||
168 | SLC15A2 | 22600 | 17194 | -0.778 | -0.0929 | No | ||
169 | EIF4EBP3 | 8429 | 17309 | -0.872 | -0.0852 | No | ||
170 | FBXL20 | 13010 | 17361 | -0.913 | -0.0735 | No | ||
171 | LMNA | 4999 15290 1778 9280 | 17568 | -1.049 | -0.0681 | No | ||
172 | GPD1 | 22361 | 17760 | -1.242 | -0.0588 | No | ||
173 | MBNL1 | 1921 15582 | 17938 | -1.428 | -0.0458 | No | ||
174 | ANP32A | 8592 4387 19415 | 18056 | -1.579 | -0.0271 | No | ||
175 | CNOT7 | 3787 9600 | 18147 | -1.689 | -0.0052 | No | ||
176 | FHOD1 | 18772 | 18271 | -1.934 | 0.0187 | No |