Table: Gene sets enriched in phenotype LMproB (6 samples) [plain text format]

	GS follow link to MSigDB	GS DETAILS	SIZE	ES	NES	NOM p-val	FDR q-val	FWER p-val	RANK AT MAX	LEADING EDGE
1	REACTOME_BASE_EXCISION_REPAIR	Details ...	14	-0.77	-1.47	0.042	1.000	1.000	1888	tags=57%, list=10%, signal=64%
2	BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2	Details ...	22	-0.73	-1.47	0.050	1.000	1.000	2208	tags=32%, list=12%, signal=36%
3	BIOCARTA_TELOMERES TELOMERASE CELLULAR AGING AND IMMORTALITY	Details ...	15	-0.77	-1.46	0.041	1.000	1.000	2569	tags=40%, list=14%, signal=46%
4	BIOCARTA_GRANZYME A MEDIATED APOPTOSIS PATHWAY	Details ...	12	-0.80	-1.46	0.044	1.000	1.000	1725	tags=42%, list=9%, signal=46%
5	REACTOME_CD28_CO_STIMULATION	Details ...	12	-0.79	-1.45	0.043	1.000	1.000	1676	tags=33%, list=9%, signal=37%
6	BIOCARTA_EUKARYOTIC PROTEIN TRANSLATION	Details ...	10	-0.82	-1.45	0.072	1.000	1.000	1129	tags=40%, list=6%, signal=43%
7	REACTOME_GLOBAL_GENOMIC_NER__GG_NER_	Details ...	28	-0.68	-1.44	0.038	1.000	1.000	987	tags=39%, list=5%, signal=41%
8	REACTOME_TELOMERE_C_STRAND__LAGGING_STRAND__SYNTHESIS	Details ...	18	-0.71	-1.44	0.064	1.000	1.000	2091	tags=61%, list=11%, signal=69%
9	BIOCARTA_HEMOGLOBINS CHAPERONE	Details ...	10	-0.81	-1.44	0.050	1.000	1.000	1817	tags=40%, list=10%, signal=44%
10	REACTOME_POLYMERASE_SWITCHING_ON_THE_C_STRAND_OF_THE_TELOMERE	Details ...	11	-0.80	-1.43	0.073	1.000	1.000	2091	tags=64%, list=11%, signal=72%
11	REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION	Details ...	14	-0.75	-1.43	0.053	1.000	1.000	1456	tags=29%, list=8%, signal=31%
12	REACTOME_RESOLUTION_OF_ABASIC_SITES__AP_SITES_	Details ...	14	-0.77	-1.43	0.054	1.000	1.000	1888	tags=57%, list=10%, signal=64%
13	REACTOME_POLYMERASE_SWITCHING	Details ...	11	-0.80	-1.42	0.065	1.000	1.000	2091	tags=64%, list=11%, signal=72%
14	REACTOME_LEADING_STRAND_SYNTHESIS	Details ...	11	-0.80	-1.41	0.050	1.000	1.000	2091	tags=64%, list=11%, signal=72%
15	BIOCARTA_CONTROL OF GENE EXPRESSION BY VITAMIN D RECEPTOR	Details ...	22	-0.67	-1.41	0.051	1.000	1.000	2699	tags=64%, list=14%, signal=74%
16	REACTOME_EXTENSION_OF_TELOMERES	Details ...	19	-0.71	-1.40	0.070	1.000	1.000	2091	tags=58%, list=11%, signal=65%
17	REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1	Details ...	11	-0.79	-1.40	0.073	1.000	1.000	367	tags=9%, list=2%, signal=9%
18	INOH_CYTOSOLIC CALCIUM ION CONCENTRATION ELEVATION (THROUGH IP3 RECEPTOR)	Details ...	14	-0.74	-1.39	0.087	1.000	1.000	1939	tags=50%, list=10%, signal=56%
19	HUMANCYC_GLYCINE BETAINE DEGRADATION	Details ...	10	-0.79	-1.39	0.085	1.000	1.000	1800	tags=30%, list=10%, signal=33%
20	INOH_PLC BETA SIGNALING	Details ...	18	-0.71	-1.39	0.072	1.000	1.000	1939	tags=44%, list=10%, signal=50%
21	REACTOME_TELOMERE_MAINTENANCE		22	-0.67	-1.38	0.060	1.000	1.000	2091	tags=50%, list=11%, signal=56%
22	BIOCARTA_ROLE OF BRCA1 BRCA2 AND ATR IN CANCER SUSCEPTIBILITY		21	-0.68	-1.38	0.072	0.997	1.000	1964	tags=24%, list=11%, signal=27%
23	REACTOME_TRNA_AMINOACYLATION		18	-0.68	-1.38	0.080	0.954	1.000	1456	tags=28%, list=8%, signal=30%
24	REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POLYMERASE_IN_TC_NER		13	-0.74	-1.36	0.107	1.000	1.000	987	tags=54%, list=5%, signal=57%
25	REACTOME_GAP_FILLING_DNA_REPAIR_SYNTHESIS_AND_LIGATION_IN_GG_NER		14	-0.72	-1.36	0.124	1.000	1.000	1888	tags=64%, list=10%, signal=71%
26	REACTOME_GAP_FILLING_DNA_REPAIR_SYNTHESIS_AND_LIGATION_IN_TC_NER		14	-0.72	-1.36	0.107	1.000	1.000	1888	tags=64%, list=10%, signal=71%
27	BIOCARTA_DOUBLE STRANDED RNA INDUCED GENE EXPRESSION		12	-0.74	-1.35	0.103	1.000	1.000	1320	tags=33%, list=7%, signal=36%
28	REACTOME_LAGGING_STRAND_SYNTHESIS		16	-0.70	-1.34	0.111	1.000	1.000	2091	tags=63%, list=11%, signal=70%
29	NCI_RXR AND RAR HETERODIMERIZATION WITH OTHER NUCLEAR RECEPTOR		19	-0.67	-1.34	0.098	0.982	1.000	3050	tags=32%, list=16%, signal=38%
30	REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS		10	-0.78	-1.33	0.109	1.000	1.000	2664	tags=40%, list=14%, signal=47%
31	REACTOME_REPAIR_SYNTHESIS_OF_PATCH__27_30_BASES_LONG__BY_DNA_POLYMERASE		13	-0.74	-1.32	0.124	1.000	1.000	987	tags=54%, list=5%, signal=57%
32	REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY		12	-0.74	-1.31	0.128	1.000	1.000	1888	tags=50%, list=10%, signal=56%
33	REACTOME_DNA_STRAND_ELONGATION		23	-0.63	-1.31	0.122	1.000	1.000	2091	tags=48%, list=11%, signal=54%
34	INOH_ERK CASCADE		12	-0.72	-1.31	0.136	1.000	1.000	1881	tags=42%, list=10%, signal=46%
35	NCI_CASPASE CASCADE IN APOPTOSIS		44	-0.55	-1.30	0.096	1.000	1.000	1762	tags=30%, list=9%, signal=33%
36	REACTOME_DNA_REPAIR		66	-0.52	-1.30	0.054	1.000	1.000	2227	tags=38%, list=12%, signal=43%
37	NCI_FOXA TRANSCRIPTION FACTOR NETWORKS		65	-0.52	-1.30	0.050	1.000	1.000	1270	tags=15%, list=7%, signal=16%
38	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE		12	-0.71	-1.30	0.168	1.000	1.000	2795	tags=33%, list=15%, signal=39%
39	BIOCARTA_RB TUMOR SUPPRESSOR/CHECKPOINT SIGNALING IN RESPONSE TO DNA DAMAGE		12	-0.71	-1.29	0.181	1.000	1.000	1335	tags=25%, list=7%, signal=27%
40	REACTOME_REMOVAL_OF_DNA_PATCH_CONTAINING_ABASIC_RESIDUE		11	-0.73	-1.29	0.178	1.000	1.000	1888	tags=45%, list=10%, signal=51%
41	BIOCARTA_INDUCTION OF APOPTOSIS THROUGH DR3 AND DR4/5 DEATH RECEPTORS		19	-0.64	-1.28	0.158	1.000	1.000	1762	tags=42%, list=9%, signal=46%
42	NCI_COREGULATION OF ANDROGEN RECEPTOR ACTIVITY		43	-0.56	-1.27	0.105	1.000	1.000	2871	tags=30%, list=15%, signal=36%
43	NCI_BARD1 SIGNALING EVENTS		26	-0.59	-1.27	0.129	1.000	1.000	1964	tags=31%, list=11%, signal=34%
44	BIOCARTA_PHOSPHOLIPIDS AS SIGNALLING INTERMEDIARIES		29	-0.58	-1.24	0.148	1.000	1.000	3098	tags=31%, list=17%, signal=37%
45	BIOCARTA_NFAT AND HYPERTROPHY OF THE HEART		42	-0.53	-1.24	0.137	1.000	1.000	2547	tags=26%, list=14%, signal=30%
46	INOH_SIGNALING WITH WNT (XENOPUS)		16	-0.64	-1.24	0.198	1.000	1.000	1845	tags=19%, list=10%, signal=21%
47	BIOCARTA_CELL CYCLE: G1/S CHECK POINT		25	-0.58	-1.23	0.174	1.000	1.000	2208	tags=28%, list=12%, signal=32%
48	REACTOME_NUCLEOTIDE_EXCISION_REPAIR		37	-0.54	-1.22	0.133	1.000	1.000	987	tags=30%, list=5%, signal=31%
49	BIOCARTA_ATM SIGNALING PATHWAY		16	-0.63	-1.21	0.223	1.000	1.000	1964	tags=31%, list=11%, signal=35%
50	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (XENOPUS)		16	-0.64	-1.21	0.233	1.000	1.000	1845	tags=19%, list=10%, signal=21%
51	REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND		12	-0.67	-1.21	0.239	1.000	1.000	2091	tags=67%, list=11%, signal=75%
52	BIOCARTA_GROWTH HORMONE SIGNALING PATHWAY		17	-0.61	-1.20	0.250	1.000	1.000	9	tags=6%, list=0%, signal=6%
53	REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX		22	-0.59	-1.20	0.212	1.000	1.000	1335	tags=32%, list=7%, signal=34%
54	BIOCARTA_REGULATION OF CELL CYCLE PROGRESSION BY PLK3		17	-0.62	-1.20	0.194	1.000	1.000	167	tags=12%, list=1%, signal=12%
55	BIOCARTA_INTERNAL RIBOSOME ENTRY PATHWAY		15	-0.62	-1.19	0.238	1.000	1.000	1734	tags=33%, list=9%, signal=37%
56	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (MAMMAL)		28	-0.55	-1.18	0.177	1.000	1.000	3116	tags=36%, list=17%, signal=43%
57	NETPATH_THROMBOPOIETIN		40	-0.51	-1.18	0.200	1.000	1.000	1332	tags=13%, list=7%, signal=13%
58	BIOCARTA_NITRIC OXIDE SIGNALING PATHWAY		16	-0.61	-1.17	0.237	1.000	1.000	2383	tags=19%, list=13%, signal=21%
59	BIOCARTA_TRKA RECEPTOR SIGNALING PATHWAY		11	-0.66	-1.17	0.284	1.000	1.000	2547	tags=27%, list=14%, signal=32%
60	BIOCARTA_P53 SIGNALING PATHWAY		13	-0.64	-1.17	0.288	1.000	1.000	1711	tags=31%, list=9%, signal=34%
61	BIOCARTA_TUMOR SUPPRESSOR ARF INHIBITS RIBOSOMAL BIOGENESIS		20	-0.59	-1.17	0.251	1.000	1.000	1068	tags=15%, list=6%, signal=16%
62	NCI_EPHA2 FORWARD SIGNALING		17	-0.59	-1.17	0.258	1.000	1.000	2775	tags=29%, list=15%, signal=35%
63	REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER		17	-0.61	-1.17	0.255	1.000	1.000	938	tags=35%, list=5%, signal=37%
64	BIOCARTA_APOPTOTIC SIGNALING IN RESPONSE TO DNA DAMAGE		14	-0.62	-1.16	0.295	1.000	1.000	167	tags=14%, list=1%, signal=14%
65	REACTOME_TOLL_LIKE_RECEPTOR_3__TLR3__CASCADE		14	-0.62	-1.16	0.279	1.000	1.000	2680	tags=57%, list=14%, signal=67%
66	REACTOME_TRANSCRIPTION_COUPLED_NER__TC_NER_		33	-0.52	-1.16	0.203	1.000	1.000	987	tags=27%, list=5%, signal=29%
67	REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE		11	-0.67	-1.16	0.305	1.000	1.000	2091	tags=64%, list=11%, signal=72%
68	REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS		26	-0.54	-1.16	0.231	1.000	1.000	1335	tags=27%, list=7%, signal=29%
69	REACTOME_DUAL_INCISION_REACTION_IN_GG_NER		17	-0.61	-1.16	0.260	1.000	1.000	938	tags=35%, list=5%, signal=37%
70	BIOCARTA_PHOSPHOINOSITIDES AND THEIR DOWNSTREAM TARGETS		21	-0.56	-1.15	0.252	1.000	1.000	543	tags=14%, list=3%, signal=15%
71	BIOCARTA_MTOR SIGNALING PATHWAY		22	-0.56	-1.15	0.262	1.000	1.000	543	tags=18%, list=3%, signal=19%
72	BIOCARTA_ROLE OF EGF RECEPTOR TRANSACTIVATION BY GPCRS IN CARDIAC HYPERTROPHY		32	-0.52	-1.15	0.232	1.000	1.000	2547	tags=31%, list=14%, signal=36%
73	BIOCARTA_HYPOXIA AND P53 IN THE CARDIOVASCULAR SYSTEM		16	-0.60	-1.15	0.277	1.000	1.000	938	tags=19%, list=5%, signal=20%
74	NCI_FC-EPSILON RECEPTOR I SIGNALING IN MAST CELLS		56	-0.47	-1.15	0.199	1.000	1.000	2775	tags=32%, list=15%, signal=38%
75	REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE		22	-0.55	-1.15	0.246	1.000	1.000	3098	tags=45%, list=17%, signal=54%
76	BIOCARTA_REGULATION OF P27 PHOSPHORYLATION DURING CELL CYCLE PROGRESSION		11	-0.65	-1.15	0.310	1.000	1.000	1727	tags=45%, list=9%, signal=50%
77	BIOCARTA_ER ASSOCIATED DEGRADATION (ERAD) PATHWAY		15	-0.61	-1.14	0.277	1.000	1.000	2156	tags=40%, list=12%, signal=45%
78	REACTOME_LOSS_OF_PROTEINS_REQUIRED_FOR_INTERPHASE_MICROTUBULE_ORGANIZATION_FROM_THE_CENTROSOME		31	-0.51	-1.14	0.259	1.000	1.000	2283	tags=39%, list=12%, signal=44%
79	HUMANCYC_GLYCOLYSIS I		20	-0.56	-1.14	0.289	1.000	1.000	2045	tags=25%, list=11%, signal=28%
80	BIOCARTA_ACTIONS OF NITRIC OXIDE IN THE HEART		39	-0.50	-1.14	0.265	1.000	1.000	2383	tags=13%, list=13%, signal=15%
81	BIOCARTA_NERVE GROWTH FACTOR PATHWAY (NGF)		15	-0.60	-1.13	0.297	1.000	1.000	3098	tags=33%, list=17%, signal=40%
82	BIOCARTA_PRION PATHWAY		16	-0.58	-1.13	0.304	1.000	1.000	964	tags=13%, list=5%, signal=13%
83	REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION		90	-0.43	-1.13	0.204	1.000	1.000	2668	tags=44%, list=14%, signal=52%
84	REACTOME_IRS_RELATED_EVENTS		21	-0.56	-1.13	0.286	1.000	1.000	3098	tags=48%, list=17%, signal=57%
85	REACTOME_SIGNALING_BY_INSULIN_RECEPTOR		22	-0.55	-1.12	0.283	1.000	1.000	3098	tags=45%, list=17%, signal=54%
86	REACTOME_INFLUENZA_INFECTION		115	-0.41	-1.12	0.175	1.000	1.000	2668	tags=42%, list=14%, signal=48%
87	REACTOME_PI3K_CASCADE		12	-0.63	-1.12	0.309	1.000	1.000	2857	tags=42%, list=15%, signal=49%
88	REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS		18	-0.57	-1.12	0.283	1.000	1.000	2383	tags=28%, list=13%, signal=32%
89	REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA_RECEPTOR		10	-0.64	-1.12	0.348	1.000	1.000	4256	tags=70%, list=23%, signal=91%
90	BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS		19	-0.56	-1.12	0.294	1.000	1.000	3098	tags=32%, list=17%, signal=38%
91	BIOCARTA_ADP-RIBOSYLATION FACTOR		18	-0.56	-1.11	0.313	1.000	1.000	2652	tags=44%, list=14%, signal=52%
92	INOH_RAF ACTIVATION SIGNALING (THROUGH GRB2 AND SOS)		11	-0.62	-1.11	0.335	1.000	1.000	3098	tags=45%, list=17%, signal=54%
93	HUMANCYC_GLYCOLYSIS III		21	-0.56	-1.11	0.349	1.000	1.000	2045	tags=24%, list=11%, signal=27%
94	REACTOME_CENTROSOME_MATURATION		33	-0.50	-1.11	0.298	1.000	1.000	2283	tags=39%, list=12%, signal=45%
95	HUMANCYC_GLYCOLYSIS V		18	-0.57	-1.11	0.306	1.000	1.000	1648	tags=22%, list=9%, signal=24%
96	NCI_IL12 SIGNALING MEDIATED BY STAT4		28	-0.53	-1.11	0.302	1.000	1.000	3113	tags=39%, list=17%, signal=47%
97	BIOCARTA_ERK1/ERK2 MAPK SIGNALING PATHWAY		20	-0.56	-1.11	0.316	0.998	1.000	2547	tags=25%, list=14%, signal=29%
98	REACTOME_CREB_PHOPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS		15	-0.58	-1.10	0.336	1.000	1.000	2383	tags=33%, list=13%, signal=38%
99	REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS		18	-0.57	-1.10	0.339	0.994	1.000	2383	tags=28%, list=13%, signal=32%
100	REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES		33	-0.50	-1.10	0.287	0.994	1.000	2283	tags=39%, list=12%, signal=45%
101	REACTOME_IRS_MEDIATED_SIGNALLING		20	-0.55	-1.10	0.343	0.996	1.000	3098	tags=45%, list=17%, signal=54%
102	REACTOME_NEURORANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE__POSTSYNAPTIC_CELL		21	-0.54	-1.10	0.305	0.989	1.000	2383	tags=24%, list=13%, signal=27%
103	NETPATH_IL3		64	-0.44	-1.09	0.252	1.000	1.000	813	tags=8%, list=4%, signal=8%
104	BIOCARTA_AGRIN IN POSTSYNAPTIC DIFFERENTIATION		44	-0.47	-1.09	0.293	0.995	1.000	2360	tags=20%, list=13%, signal=23%
105	BIOCARTA_CHAPERONES MODULATE INTERFERON SIGNALING PATHWAY		16	-0.57	-1.09	0.330	0.986	1.000	1320	tags=19%, list=7%, signal=20%
106	REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT		53	-0.46	-1.09	0.294	0.978	1.000	2530	tags=43%, list=14%, signal=50%
107	REACTOME_CAP_DEPENDENT_TRANSLATION_INITIATION		58	-0.44	-1.09	0.281	0.983	1.000	2530	tags=40%, list=14%, signal=46%
108	NCI_MTOR SIGNALING PATHWAY		24	-0.50	-1.08	0.321	0.989	1.000	727	tags=21%, list=4%, signal=22%
109	NCI_FOXA1 TRANSCRIPTION FACTOR NETWORK		33	-0.49	-1.08	0.344	0.981	1.000	2907	tags=27%, list=16%, signal=32%
110	REACTOME_G2_M_TRANSITION		44	-0.46	-1.08	0.320	0.979	1.000	2283	tags=34%, list=12%, signal=39%
111	REACTOME_G2_M_CHECKPOINTS		30	-0.49	-1.08	0.332	0.972	1.000	1335	tags=23%, list=7%, signal=25%
112	REACTOME_RIBOSOMAL_SCANNING_AND_START_CODON_RECOGNITION		30	-0.49	-1.08	0.313	0.966	1.000	2469	tags=47%, list=13%, signal=54%
113	INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY		132	-0.39	-1.08	0.241	0.959	1.000	2165	tags=24%, list=12%, signal=27%
114	BIOCARTA_TRANSCRIPTION REGULATION BY METHYLTRANSFERASE OF CARM1		12	-0.61	-1.08	0.376	0.961	1.000	1102	tags=17%, list=6%, signal=18%
115	CELLMAP_WNT		65	-0.43	-1.07	0.288	0.960	1.000	2427	tags=22%, list=13%, signal=25%
116	REACTOME_EUKARYOTIC_TRANSLATION_INITIATION		58	-0.44	-1.07	0.306	0.954	1.000	2530	tags=40%, list=14%, signal=46%
117	NCI_HYPOXIC AND OXYGEN HOMEOSTASIS REGULATION OF HIF-1-ALPHA		67	-0.43	-1.07	0.343	0.948	1.000	1648	tags=16%, list=9%, signal=18%
118	INOH_BETA CATENIN DEGRADATION SIGNALING (MAMMAL)		19	-0.55	-1.07	0.374	0.957	1.000	3116	tags=42%, list=17%, signal=51%
119	NCI_NONGENOTROPIC ANDROGEN SIGNALING		24	-0.51	-1.06	0.361	0.964	1.000	3098	tags=33%, list=17%, signal=40%
120	NCI_FAS SIGNALING PATHWAY (CD95)		31	-0.48	-1.06	0.362	0.957	1.000	1762	tags=26%, list=9%, signal=28%
121	BIOCARTA_RAS SIGNALING PATHWAY		19	-0.53	-1.06	0.355	0.957	1.000	1320	tags=21%, list=7%, signal=23%
122	BIOCARTA_IGF-1 SIGNALING PATHWAY		19	-0.52	-1.06	0.350	0.958	1.000	2547	tags=21%, list=14%, signal=24%
123	NCI_FOXA2 AND FOXA3 TRANSCRIPTION FACTOR NETWORKS		37	-0.46	-1.06	0.314	0.958	1.000	1270	tags=14%, list=7%, signal=14%
124	NETPATH_EPO		39	-0.46	-1.05	0.348	0.966	1.000	518	tags=8%, list=3%, signal=8%
125	NCI_FOXM1 TRANSCRIPTION FACTOR NETWORK		34	-0.46	-1.05	0.353	0.964	1.000	2133	tags=32%, list=11%, signal=36%
126	BIOCARTA_OXIDATIVE STRESS INDUCED GENE EXPRESSION VIA NRF2		16	-0.55	-1.05	0.391	0.960	1.000	770	tags=19%, list=4%, signal=20%
127	BIOCARTA_ASPIRIN BLOCKS SIGNALING PATHWAY INVOLVED IN PLATELET ACTIVATION		16	-0.54	-1.05	0.388	0.955	1.000	2360	tags=25%, list=13%, signal=29%
128	REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS		43	-0.45	-1.05	0.348	0.960	1.000	1839	tags=35%, list=10%, signal=39%
129	REACTOME_GENE_EXPRESSION		145	-0.38	-1.05	0.291	0.953	1.000	2227	tags=29%, list=12%, signal=33%
130	REACTOME_L13A_MEDIATED_TRANSLATIONAL_SILENCING_OF_CERULOPLASMIN_EXPRESSION		52	-0.43	-1.04	0.350	0.953	1.000	2530	tags=42%, list=14%, signal=49%
131	NCI_INTEGRINS IN ANGIOGENESIS		63	-0.42	-1.04	0.337	0.952	1.000	2775	tags=27%, list=15%, signal=32%
132	REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS		12	-0.57	-1.04	0.405	0.950	1.000	1964	tags=58%, list=11%, signal=65%
133	NCI_SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA		46	-0.44	-1.04	0.365	0.945	1.000	586	tags=13%, list=3%, signal=13%
134	BIOCARTA_ESTROGEN RESPONSIVE PROTEIN EFP CONTROLS CELL CYCLE AND BREAST TUMORS GROWTH		13	-0.56	-1.04	0.440	0.939	1.000	2165	tags=31%, list=12%, signal=35%
135	BIOCARTA_REPRESSION OF PAIN SENSATION BY THE TRANSCRIPTIONAL REGULATOR DREAM		14	-0.55	-1.04	0.423	0.942	1.000	770	tags=14%, list=4%, signal=15%
136	REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS		13	-0.57	-1.04	0.410	0.938	1.000	1628	tags=23%, list=9%, signal=25%
137	REACTOME_INFLUENZA_LIFE_CYCLE		111	-0.38	-1.04	0.360	0.932	1.000	2668	tags=40%, list=14%, signal=46%
138	NCI_ANDROGEN-MEDIATED SIGNALING		101	-0.39	-1.03	0.328	0.934	1.000	3116	tags=32%, list=17%, signal=38%
139	HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS AND ENTNER-DOUDOROFF		22	-0.50	-1.03	0.399	0.942	1.000	2045	tags=27%, list=11%, signal=31%
140	REACTOME_TRAF6_MEDIATED_INDUCTION_OF_THE_ANTIVIRAL_CYTOKINE_IFN_ALPHA_BETA_CASCADE		12	-0.58	-1.03	0.472	0.937	1.000	2680	tags=50%, list=14%, signal=58%
141	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR__IGF__ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS__IGFBPS_		12	-0.56	-1.03	0.430	0.931	1.000	504	tags=8%, list=3%, signal=9%
142	REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_TERMINATION		16	-0.53	-1.03	0.421	0.925	1.000	2447	tags=38%, list=13%, signal=43%
143	REACTOME__3___UTR_MEDIATED_TRANSLATIONAL_REGULATION		52	-0.43	-1.03	0.377	0.922	1.000	2530	tags=42%, list=14%, signal=49%
144	BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY		27	-0.48	-1.03	0.401	0.918	1.000	927	tags=11%, list=5%, signal=12%
145	REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION		15	-0.53	-1.03	0.433	0.916	1.000	2447	tags=40%, list=13%, signal=46%
146	NCI_EPHRINA-EPHA PATHWAY		40	-0.45	-1.02	0.371	0.915	1.000	3122	tags=28%, list=17%, signal=33%
147	REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR		12	-0.57	-1.02	0.460	0.910	1.000	1964	tags=58%, list=11%, signal=65%
148	REACTOME_RNA_POLYMERASE_I_CHAIN_ELONGATION		15	-0.54	-1.02	0.440	0.916	1.000	758	tags=20%, list=4%, signal=21%
149	REACTOME_MRNA_SPLICING		67	-0.40	-1.02	0.398	0.910	1.000	1885	tags=33%, list=10%, signal=36%
150	NCI_REGULATION OF RETINOBLASTOMA PROTEIN		58	-0.41	-1.01	0.412	0.924	1.000	1711	tags=17%, list=9%, signal=19%
151	HUMANCYC_PHOSPHOLIPASES		22	-0.49	-1.01	0.410	0.920	1.000	1381	tags=18%, list=7%, signal=20%
152	REACTOME_VIRAL_MRNA_TRANSLATION		46	-0.43	-1.01	0.416	0.921	1.000	2530	tags=46%, list=14%, signal=53%
153	BIOCARTA_INTEGRIN SIGNALING PATHWAY		30	-0.46	-1.01	0.435	0.919	1.000	2775	tags=27%, list=15%, signal=31%
154	REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION		30	-0.46	-1.01	0.402	0.917	1.000	2469	tags=43%, list=13%, signal=50%
155	BIOCARTA_CASPASE CASCADE IN APOPTOSIS		21	-0.50	-1.01	0.461	0.914	1.000	2423	tags=38%, list=13%, signal=44%
156	REACTOME_MRNA_SPLICING___MAJOR_PATHWAY		67	-0.40	-1.01	0.410	0.909	1.000	1885	tags=33%, list=10%, signal=36%
157	REACTOME_PHASE_II_CONJUGATION		17	-0.52	-1.00	0.472	0.920	1.000	1772	tags=12%, list=10%, signal=13%
158	BIOCARTA_TNF/STRESS RELATED SIGNALING		22	-0.49	-1.00	0.439	0.916	1.000	1893	tags=36%, list=10%, signal=40%
159	REACTOME_TRANSLATION		63	-0.41	-1.00	0.440	0.914	1.000	2530	tags=37%, list=14%, signal=42%
160	NCI_AURORA B SIGNALING		33	-0.45	-0.99	0.466	0.938	1.000	1671	tags=21%, list=9%, signal=23%
161	REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS__AND_SUBSEQUENT_BINDING_TO_43S		31	-0.46	-0.99	0.455	0.938	1.000	2469	tags=42%, list=13%, signal=48%
162	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA		85	-0.38	-0.99	0.458	0.936	1.000	1951	tags=29%, list=10%, signal=33%
163	BIOCARTA_IL12 AND STAT4 DEPENDENT SIGNALING PATHWAY IN TH1 DEVELOPMENT		15	-0.52	-0.99	0.472	0.933	1.000	2988	tags=53%, list=16%, signal=63%
164	BIOCARTA_REGULATION OF EIF2		10	-0.56	-0.99	0.492	0.928	1.000	1878	tags=30%, list=10%, signal=33%
165	BIOCARTA_INFLUENCE OF RAS AND RHO PROTEINS ON G1 TO S TRANSITION		28	-0.46	-0.99	0.475	0.930	1.000	1711	tags=25%, list=9%, signal=27%
166	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS III		30	-0.46	-0.98	0.469	0.932	1.000	1102	tags=17%, list=6%, signal=18%
167	REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS		86	-0.37	-0.98	0.487	0.930	1.000	1885	tags=30%, list=10%, signal=33%
168	BIOCARTA_CHROMATIN REMODELING BY HSWI/SNF ATP-DEPENDENT COMPLEXES		15	-0.52	-0.98	0.493	0.925	1.000	1801	tags=47%, list=10%, signal=52%
169	INOH_GENE EXPRESSION OF SOCS BY STAT DIMER		13	-0.53	-0.98	0.491	0.925	1.000	4	tags=8%, list=0%, signal=8%
170	BIOCARTA_INACTIVATION OF GSK3 BY AKT CAUSES ACCUMULATION OF B-CATENIN IN ALVEOLAR MACROPHAGES		38	-0.43	-0.98	0.464	0.927	1.000	1974	tags=24%, list=11%, signal=26%
171	BIOCARTA_MECHANISMS OF TRANSCRIPTIONAL REPRESSION BY DNA METHYLATION		14	-0.53	-0.98	0.490	0.922	1.000	2223	tags=36%, list=12%, signal=41%
172	REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS		44	-0.41	-0.98	0.491	0.919	1.000	2530	tags=45%, list=14%, signal=52%
173	REACTOME_SYNAPTIC_TRANSMISSION		42	-0.42	-0.98	0.486	0.916	1.000	575	tags=10%, list=3%, signal=10%
174	REACTOME_ELONGATION_OF_INTRON_CONTAINING_TRANSCRIPTS_AND_CO_TRANSCRIPTIONAL_MRNA_SPLICING		86	-0.37	-0.97	0.485	0.919	1.000	1885	tags=30%, list=10%, signal=33%
175	NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING		40	-0.42	-0.97	0.507	0.924	1.000	2360	tags=20%, list=13%, signal=23%
176	REACTOME_DNA_REPLICATION		69	-0.38	-0.97	0.516	0.919	1.000	987	tags=20%, list=5%, signal=21%
177	BIOCARTA_REGULATION OF EIF-4E AND P70S6 KINASE		22	-0.47	-0.97	0.504	0.914	1.000	543	tags=14%, list=3%, signal=14%
178	NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY		32	-0.43	-0.97	0.481	0.914	1.000	3395	tags=44%, list=18%, signal=53%
179	INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY		196	-0.34	-0.97	0.518	0.911	1.000	2383	tags=21%, list=13%, signal=24%
180	BIOCARTA_REGULATION OF TRANSCRIPTIONAL ACTIVITY BY PML		10	-0.56	-0.97	0.523	0.910	1.000	1102	tags=20%, list=6%, signal=21%
181	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING		12	-0.52	-0.97	0.507	0.906	1.000	1291	tags=25%, list=7%, signal=27%
182	BIOCARTA_CARM1 AND REGULATION OF THE ESTROGEN RECEPTOR		11	-0.54	-0.96	0.521	0.910	1.000	1102	tags=36%, list=6%, signal=39%
183	REACTOME_GLUCONEOGENESIS		11	-0.55	-0.96	0.509	0.906	1.000	529	tags=18%, list=3%, signal=19%
184	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES		41	-0.42	-0.96	0.526	0.901	1.000	575	tags=10%, list=3%, signal=10%
185	INOH_JNK CASCADE		16	-0.50	-0.96	0.520	0.901	1.000	1893	tags=31%, list=10%, signal=35%
186	BIOCARTA_THE INFORMATION PROCESSING PATHWAY AT THE IFN BETA ENHANCER		26	-0.45	-0.96	0.483	0.913	1.000	1801	tags=38%, list=10%, signal=43%
187	REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY		22	-0.46	-0.96	0.523	0.910	1.000	1676	tags=18%, list=9%, signal=20%
188	BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY		24	-0.45	-0.95	0.506	0.910	1.000	1790	tags=29%, list=10%, signal=32%
189	REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING		15	-0.50	-0.95	0.519	0.907	1.000	1632	tags=27%, list=9%, signal=29%
190	BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF		17	-0.49	-0.95	0.501	0.903	1.000	2360	tags=29%, list=13%, signal=34%
191	CELLMAP_NOTCH		45	-0.41	-0.95	0.525	0.901	1.000	2358	tags=22%, list=13%, signal=25%
192	NCI_REGULATION OF ANDROGEN RECEPTOR ACTIVITY		80	-0.37	-0.95	0.560	0.896	1.000	2208	tags=21%, list=12%, signal=24%
193	REACTOME_DOUBLE_STRAND_BREAK_REPAIR		17	-0.49	-0.95	0.531	0.895	1.000	1964	tags=47%, list=11%, signal=53%
194	REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS		11	-0.53	-0.95	0.527	0.893	1.000	3678	tags=64%, list=20%, signal=79%
195	HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION		22	-0.47	-0.95	0.531	0.889	1.000	1648	tags=23%, list=9%, signal=25%
196	CELLMAP_ANDROGENRECEPTOR		70	-0.38	-0.95	0.536	0.885	1.000	2208	tags=26%, list=12%, signal=29%
197	BIOCARTA_BCR SIGNALING PATHWAY		29	-0.44	-0.95	0.556	0.892	1.000	2694	tags=41%, list=14%, signal=48%
198	REACTOME_EUKARYOTIC_TRANSLATION_TERMINATION		46	-0.40	-0.95	0.551	0.890	1.000	2530	tags=43%, list=14%, signal=50%
199	REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS		22	-0.47	-0.95	0.539	0.887	1.000	1704	tags=27%, list=9%, signal=30%
200	REACTOME_SYNTHESIS_OF_DNA		65	-0.37	-0.94	0.555	0.886	1.000	987	tags=20%, list=5%, signal=21%
201	BIOCARTA_EXTRINSIC PROTHROMBIN ACTIVATION PATHWAY		12	-0.52	-0.94	0.542	0.885	1.000	2211	tags=25%, list=12%, signal=28%
202	BIOCARTA_ATTENUATION OF GPCR SIGNALING		11	-0.53	-0.94	0.546	0.884	1.000	1881	tags=18%, list=10%, signal=20%
203	INOH_PHOSPHOLIPASE C GAMMA SIGNALING		48	-0.39	-0.94	0.580	0.895	1.000	2775	tags=35%, list=15%, signal=42%
204	REACTOME_DEATH_RECEPTOR__SIGNALLING		11	-0.53	-0.94	0.562	0.891	1.000	3678	tags=64%, list=20%, signal=79%
205	REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING		15	-0.50	-0.94	0.550	0.889	1.000	1632	tags=27%, list=9%, signal=29%
206	REACTOME_CELL_CYCLE__MITOTIC		143	-0.34	-0.93	0.628	0.887	1.000	2168	tags=27%, list=12%, signal=31%
207	REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION		19	-0.47	-0.93	0.562	0.884	1.000	2447	tags=32%, list=13%, signal=36%
208	REACTOME_METABOLISM_OF_PROTEINS		98	-0.35	-0.93	0.614	0.883	1.000	2530	tags=32%, list=14%, signal=36%
209	BIOCARTA_SKELETAL MUSCLE HYPERTROPHY IS REGULATED VIA AKT-MTOR PATHWAY		24	-0.45	-0.93	0.548	0.884	1.000	543	tags=13%, list=3%, signal=13%
210	BIOCARTA_B CELL SURVIVAL PATHWAY		12	-0.51	-0.93	0.557	0.880	1.000	2133	tags=25%, list=11%, signal=28%
211	BIOCARTA_VEGF HYPOXIA AND ANGIOGENESIS		28	-0.43	-0.93	0.585	0.879	1.000	2775	tags=21%, list=15%, signal=25%
212	BIOCARTA_FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS		27	-0.44	-0.93	0.559	0.881	1.000	2547	tags=33%, list=14%, signal=39%
213	REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS		19	-0.47	-0.92	0.586	0.886	1.000	1984	tags=32%, list=11%, signal=35%
214	REACTOME_PEPTIDE_CHAIN_ELONGATION		45	-0.40	-0.92	0.571	0.888	1.000	2530	tags=44%, list=14%, signal=51%
215	BIOCARTA_UCALPAIN AND FRIENDS IN CELL SPREAD		13	-0.50	-0.92	0.574	0.887	1.000	747	tags=15%, list=4%, signal=16%
216	NCI_WNT SIGNALING		49	-0.38	-0.92	0.586	0.891	1.000	2208	tags=16%, list=12%, signal=18%
217	NCI_SIGNALING EVENTS MEDIATED BY THE HEDGEHOG FAMILY		59	-0.37	-0.92	0.639	0.893	1.000	2523	tags=24%, list=14%, signal=27%
218	HUMANCYC_TRIACYLGLYCEROL DEGRADATION		12	-0.50	-0.91	0.571	0.893	1.000	4003	tags=33%, list=22%, signal=42%
219	REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS		19	-0.47	-0.91	0.597	0.893	1.000	1984	tags=32%, list=11%, signal=35%
220	BIOCARTA_CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES		15	-0.48	-0.91	0.600	0.900	1.000	2360	tags=33%, list=13%, signal=38%
221	REACTOME_S_PHASE		74	-0.36	-0.91	0.670	0.901	1.000	999	tags=19%, list=5%, signal=20%
222	NETPATH_IFN-GAMMA		67	-0.36	-0.91	0.693	0.897	1.000	2383	tags=27%, list=13%, signal=31%
223	NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS		44	-0.39	-0.91	0.644	0.894	1.000	2523	tags=30%, list=14%, signal=34%
224	INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (CANONICAL)		31	-0.41	-0.90	0.586	0.904	1.000	3116	tags=35%, list=17%, signal=43%
225	REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS		18	-0.46	-0.90	0.607	0.906	1.000	2795	tags=28%, list=15%, signal=33%
226	NCI_CANONICAL WNT SIGNALING PATHWAY		49	-0.38	-0.90	0.671	0.904	1.000	2208	tags=16%, list=12%, signal=18%
227	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION		47	-0.38	-0.90	0.677	0.904	1.000	2530	tags=43%, list=14%, signal=49%
228	NCI_SYNDECAN-4-MEDIATED SIGNALING EVENTS		47	-0.38	-0.90	0.646	0.901	1.000	1881	tags=15%, list=10%, signal=17%
229	BIOCARTA_CERAMIDE SIGNALING PATHWAY		48	-0.37	-0.90	0.640	0.899	1.000	1762	tags=27%, list=9%, signal=30%
230	BIOCARTA_CYCLINS AND CELL CYCLE REGULATION		22	-0.43	-0.89	0.619	0.904	1.000	1711	tags=27%, list=9%, signal=30%
231	INOH_CD4 T CELL RECEPTOR SIGNALING (THROUGH VAV, RAC AND JNK CASCADE		36	-0.39	-0.89	0.626	0.910	1.000	1939	tags=25%, list=10%, signal=28%
232	INOH_DROSOPHILA TOLL-LIKE RECEPTOR SIGNALING		193	-0.31	-0.89	0.865	0.908	1.000	2168	tags=19%, list=12%, signal=21%
233	NCI_VEGFR1 SPECIFIC SIGNALS		27	-0.41	-0.89	0.634	0.906	1.000	2360	tags=22%, list=13%, signal=25%
234	NCI_EPHA FORWARD SIGNALING		30	-0.41	-0.88	0.644	0.910	1.000	3122	tags=23%, list=17%, signal=28%
235	NCI_PDGFR-ALPHA SIGNALING PATHWAY		20	-0.43	-0.87	0.639	0.938	1.000	770	tags=10%, list=4%, signal=10%
236	BIOCARTA_METS AFFECT ON MACROPHAGE DIFFERENTIATION		17	-0.45	-0.87	0.642	0.935	1.000	1068	tags=24%, list=6%, signal=25%
237	BIOCARTA_CELL CYCLE: G2/M CHECKPOINT		19	-0.43	-0.87	0.630	0.943	1.000	8	tags=5%, list=0%, signal=5%
238	REACTOME_METABOLISM_OF_MRNA		15	-0.45	-0.86	0.681	0.948	1.000	679	tags=20%, list=4%, signal=21%
239	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH		20	-0.42	-0.86	0.646	0.944	1.000	1084	tags=15%, list=6%, signal=16%
240	INOH_TGF BETA SIGNALING PATHWAY(THROUGH TAK1)		13	-0.47	-0.86	0.660	0.944	1.000	3180	tags=31%, list=17%, signal=37%
241	BIOCARTA_HOW PROGESTERONE INITIATES THE OOCYTE MATURATION		19	-0.43	-0.86	0.654	0.944	1.000	2360	tags=21%, list=13%, signal=24%
242	REACTOME_PYRIMIDINE_METABOLISM		17	-0.45	-0.86	0.686	0.944	1.000	2141	tags=41%, list=12%, signal=46%
243	REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY		15	-0.45	-0.86	0.688	0.944	1.000	679	tags=20%, list=4%, signal=21%
244	NCI_CIRCADIAN RHYTHM PATHWAY		11	-0.48	-0.85	0.682	0.947	1.000	2007	tags=36%, list=11%, signal=41%
245	BIOCARTA_WNT SIGNALING PATHWAY		28	-0.39	-0.85	0.696	0.949	1.000	2208	tags=18%, list=12%, signal=20%
246	NCI_GLYPICAN 3 NETWORK		57	-0.35	-0.85	0.820	0.961	1.000	2208	tags=16%, list=12%, signal=18%
247	HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS II		22	-0.41	-0.84	0.701	0.963	1.000	1605	tags=27%, list=9%, signal=30%
248	BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY		45	-0.36	-0.84	0.748	0.961	1.000	2652	tags=29%, list=14%, signal=34%
249	REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION		21	-0.41	-0.84	0.706	0.961	1.000	2091	tags=24%, list=11%, signal=27%
250	REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT		19	-0.41	-0.84	0.704	0.962	1.000	1951	tags=26%, list=10%, signal=29%
251	NCI_ALPHA-SYNUCLEIN SIGNALING		32	-0.37	-0.84	0.748	0.961	1.000	2360	tags=22%, list=13%, signal=25%
252	BIOCARTA_SIGNALING PATHWAY FROM G-PROTEIN FAMILIES		23	-0.40	-0.84	0.755	0.959	1.000	2383	tags=17%, list=13%, signal=20%
253	INOH_BETA CATENIN DEGRADATION SIGNALING (CANONICAL)		22	-0.41	-0.83	0.713	0.962	1.000	2427	tags=32%, list=13%, signal=37%
254	REACTOME_E2F_TRANSCRIPTIONAL_TARGETS_AT_G1_S		14	-0.43	-0.83	0.709	0.977	1.000	1711	tags=21%, list=9%, signal=24%
255	NCI_SIGNALING EVENTS MEDIATED BY VEGFR1 AND VEGFR2		62	-0.33	-0.82	0.853	0.981	1.000	2775	tags=19%, list=15%, signal=23%
256	REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PEROXISOME_PROLIFERATOR_ACTIVATED_RECEPTOR_ALPHA__PPARALPHA_		11	-0.46	-0.82	0.708	0.980	1.000	906	tags=9%, list=5%, signal=10%
257	INOH_SIGNALING WITHOUT WNT (MAMMAL)		24	-0.40	-0.82	0.711	0.977	1.000	1887	tags=21%, list=10%, signal=23%
258	BIOCARTA_CDK REGULATION OF DNA REPLICATION		18	-0.42	-0.82	0.737	0.977	1.000	1711	tags=22%, list=9%, signal=24%
259	INOH_T CELL RECEPTOR SIGNALING PATHWAY		51	-0.34	-0.81	0.840	0.982	1.000	2775	tags=31%, list=15%, signal=37%
260	REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE		13	-0.44	-0.81	0.732	0.978	1.000	2195	tags=38%, list=12%, signal=44%
261	REACTOME_AXON_GUIDANCE		56	-0.33	-0.81	0.866	0.982	1.000	1291	tags=13%, list=7%, signal=13%
262	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS		20	-0.41	-0.81	0.758	0.980	1.000	1951	tags=25%, list=10%, signal=28%
263	REACTOME_TIE2_SIGNALING		12	-0.46	-0.81	0.738	0.983	1.000	2588	tags=25%, list=14%, signal=29%
264	BIOCARTA_NUCLEAR RECEPTORS COORDINATE THE ACTIVITIES OF CHROMATIN REMODELING COMPLEXES AND COACTIVATORS TO FACILITATE INITIATION OF TRANSCRIPTION IN CARCINOMA CELLS		14	-0.43	-0.81	0.743	0.981	1.000	269	tags=14%, list=1%, signal=14%
265	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES		13	-0.44	-0.80	0.767	0.980	1.000	83	tags=8%, list=0%, signal=8%
266	BIOCARTA_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF		50	-0.33	-0.80	0.885	0.986	1.000	1762	tags=24%, list=9%, signal=26%
267	BIOCARTA_KERATINOCYTE DIFFERENTIATION		51	-0.33	-0.79	0.915	0.991	1.000	1893	tags=25%, list=10%, signal=28%
268	BIOCARTA_CORTICOSTEROIDS AND CARDIOPROTECTION		25	-0.37	-0.79	0.819	0.988	1.000	1212	tags=8%, list=7%, signal=9%
269	NCI_NONCANONICAL WNT SIGNALING PATHWAY		18	-0.39	-0.78	0.807	1.000	1.000	1845	tags=17%, list=10%, signal=18%
270	REACTOME_BIOLOGICAL_OXIDATIONS		46	-0.33	-0.78	0.880	1.000	1.000	1772	tags=7%, list=10%, signal=7%
271	BIOCARTA_TPO SIGNALING PATHWAY		22	-0.37	-0.78	0.824	1.000	1.000	2547	tags=18%, list=14%, signal=21%
272	NCI_OSTEOPONTIN-MEDIATED EVENTS		29	-0.36	-0.77	0.830	1.000	1.000	1704	tags=24%, list=9%, signal=27%
273	BIOCARTA_ENDOCYTOTIC ROLE OF NDK PHOSPHINS AND DYNAMIN		14	-0.42	-0.77	0.792	1.000	1.000	1333	tags=29%, list=7%, signal=31%
274	NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY		22	-0.37	-0.77	0.835	1.000	1.000	3395	tags=36%, list=18%, signal=44%
275	NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS		68	-0.30	-0.77	0.953	1.000	1.000	1787	tags=12%, list=10%, signal=13%
276	HUMANCYC_SUPERPATHWAY OF HISTIDINE, PURINE, AND PYRIMIDINE BIOSYNTHESIS		33	-0.34	-0.77	0.880	1.000	1.000	2452	tags=33%, list=13%, signal=38%
277	REACTOME_TOLL_RECEPTOR_CASCADES		26	-0.36	-0.77	0.843	0.999	1.000	1762	tags=31%, list=9%, signal=34%
278	BIOCARTA_TNFR1 SIGNALING PATHWAY		16	-0.40	-0.77	0.784	0.997	1.000	1762	tags=31%, list=9%, signal=34%
279	INOH_G ALPHA S GDP-GTP EXCHANGE SIGNALING		105	-0.29	-0.77	0.990	0.994	1.000	2644	tags=17%, list=14%, signal=20%
280	BIOCARTA_ROLE OF NICOTINIC ACETYLCHOLINE RECEPTORS IN THE REGULATION OF APOPTOSIS		17	-0.39	-0.77	0.821	0.992	1.000	3136	tags=35%, list=17%, signal=42%
281	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS		24	-0.36	-0.77	0.846	0.991	1.000	3049	tags=33%, list=16%, signal=40%
282	BIOCARTA_MECHANISM OF GENE REGULATION BY PEROXISOME PROLIFERATORS VIA PPARA		33	-0.33	-0.76	0.915	0.996	1.000	1102	tags=12%, list=6%, signal=13%
283	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS		53	-0.31	-0.76	0.950	0.999	1.000	1001	tags=4%, list=5%, signal=4%
284	REACTOME_SHC_RELATED_EVENTS		10	-0.44	-0.76	0.805	0.996	1.000	3098	tags=50%, list=17%, signal=60%
285	BIOCARTA_THROMBIN SIGNALING AND PROTEASE-ACTIVATED RECEPTORS		19	-0.38	-0.75	0.842	0.993	1.000	2628	tags=32%, list=14%, signal=37%
286	REACTOME_GRB2_EVENTS_IN_EGFR_SIGNALING		10	-0.43	-0.75	0.800	0.997	1.000	3098	tags=50%, list=17%, signal=60%
287	REACTOME_SHC_EVENTS_IN_EGFR_SIGNALING		11	-0.42	-0.75	0.818	0.999	1.000	3098	tags=45%, list=17%, signal=54%
288	BIOCARTA_RAS-INDEPENDENT PATHWAY IN NK CELL-MEDIATED CYTOTOXICITY		19	-0.38	-0.74	0.857	1.000	1.000	1565	tags=16%, list=8%, signal=17%
289	REACTOME_MUSCLE_CONTRACTION		25	-0.35	-0.74	0.877	0.999	1.000	533	tags=8%, list=3%, signal=8%
290	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE)		32	-0.33	-0.74	0.929	0.996	1.000	2775	tags=34%, list=15%, signal=40%
291	REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS		11	-0.42	-0.74	0.839	0.993	1.000	1704	tags=27%, list=9%, signal=30%
292	HUMANCYC_DE NOVO BIOSYNTHESIS OF PYRIMIDINE RIBONUCLEOTIDES		11	-0.43	-0.74	0.846	0.991	1.000	1673	tags=45%, list=9%, signal=50%
293	REACTOME_STRIATED_MUSCLE_CONTRACTION		14	-0.40	-0.74	0.857	0.992	1.000	1912	tags=14%, list=10%, signal=16%
294	HUMANCYC_SALVAGE PATHWAYS OF PYRIMIDINE RIBONUCLEOTIDES		12	-0.41	-0.73	0.847	0.996	1.000	1673	tags=25%, list=9%, signal=27%
295	BIOCARTA_CCR3 SIGNALING IN EOSINOPHILS		21	-0.35	-0.72	0.884	1.000	1.000	3098	tags=29%, list=17%, signal=34%
296	REACTOME_PI3K_AKT_SIGNALLING		12	-0.39	-0.71	0.857	1.000	1.000	1320	tags=17%, list=7%, signal=18%
297	BIOCARTA_ERK AND PI-3 KINASE ARE NECESSARY FOR COLLAGEN BINDING IN CORNEAL EPITHELIA		28	-0.33	-0.70	0.949	1.000	1.000	862	tags=11%, list=5%, signal=11%
298	BIOCARTA_HYPOXIA-INDUCIBLE FACTOR IN THE CARDIVASCULAR SYSTEM		14	-0.38	-0.70	0.905	1.000	1.000	1626	tags=21%, list=9%, signal=23%
299	REACTOME_MEMBRANE_TRAFFICKING		26	-0.32	-0.70	0.952	1.000	1.000	1632	tags=19%, list=9%, signal=21%
300	HUMANCYC_ENTNER-DOUDOROFF PATHWAY II (NON-PHOSPHORYLATIVE)		12	-0.37	-0.69	0.900	1.000	1.000	1692	tags=25%, list=9%, signal=27%
301	BIOCARTA_FMLP INDUCED CHEMOKINE GENE EXPRESSION IN HMC-1 CELLS		28	-0.33	-0.69	0.962	1.000	1.000	2383	tags=29%, list=13%, signal=33%
302	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION		16	-0.36	-0.69	0.893	1.000	1.000	2153	tags=31%, list=12%, signal=35%
303	HUMANCYC_PURINE NUCLEOTIDES DE NOVO BIOSYNTHESIS II		10	-0.40	-0.69	0.890	1.000	1.000	2452	tags=40%, list=13%, signal=46%
304	NETPATH_TIE1_TEK		24	-0.33	-0.69	0.942	1.000	1.000	2775	tags=21%, list=15%, signal=24%
305	BIOCARTA_IL 3 SIGNALING PATHWAY		11	-0.38	-0.68	0.898	1.000	1.000	2547	tags=27%, list=14%, signal=32%
306	REACTOME_GAMMA_CARBOXYLATION__TRANSPORT__AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS		10	-0.39	-0.68	0.882	1.000	1.000	1505	tags=20%, list=8%, signal=22%
307	REACTOME_PLATELET_AGGREGATION__PLUG_FORMATION_		18	-0.34	-0.67	0.944	1.000	1.000	2843	tags=28%, list=15%, signal=33%
308	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER		10	-0.38	-0.67	0.900	1.000	1.000	2153	tags=40%, list=12%, signal=45%
309	REACTOME_INTEGRIN_ALPHAIIBBETA3_SIGNALING		17	-0.34	-0.67	0.930	1.000	1.000	2843	tags=29%, list=15%, signal=35%
310	BIOCARTA_SUMOYLATION BY RANBP2 REGULATES TRANSCRIPTIONAL REPRESSION		12	-0.35	-0.65	0.910	1.000	1.000	2645	tags=33%, list=14%, signal=39%
311	BIOCARTA_PDGF SIGNALING PATHWAY		24	-0.31	-0.64	0.973	1.000	1.000	1881	tags=17%, list=10%, signal=19%
312	REACTOME_DOWN_STREAM_SIGNAL_TRANSDUCTION		17	-0.32	-0.64	0.961	1.000	1.000	2360	tags=24%, list=13%, signal=27%
313	REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING		10	-0.36	-0.62	0.925	1.000	1.000	2205	tags=40%, list=12%, signal=45%
314	REACTOME_SIGNALING_BY_PDGF		21	-0.31	-0.62	0.976	1.000	1.000	2360	tags=19%, list=13%, signal=22%
315	BIOCARTA_G-PROTEIN SIGNALING THROUGH TUBBY PROTEINS		10	-0.36	-0.62	0.938	1.000	1.000	1212	tags=10%, list=7%, signal=11%
316	REACTOME_COOPERATION_OF_PREFOLDIN_AND_TRIC_CCT__IN_ACTIN_AND_TUBULIN_FOLDING		10	-0.36	-0.62	0.928	1.000	1.000	2205	tags=40%, list=12%, signal=45%
317	BIOCARTA_INTRINSIC PROTHROMBIN ACTIVATION PATHWAY		22	-0.29	-0.60	0.984	1.000	1.000	1505	tags=9%, list=8%, signal=10%
318	REACTOME_EGFR_DOWNREGULATION		10	-0.34	-0.59	0.964	1.000	1.000	3337	tags=30%, list=18%, signal=37%
319	REACTOME_SIGNALLING_TO_ERKS		13	-0.31	-0.59	0.963	1.000	1.000	2360	tags=23%, list=13%, signal=26%
320	BIOCARTA_ROLE OF FL-ARRESTINS IN THE ACTIVATION AND TARGETING OF MAP KINASES		28	-0.27	-0.58	0.995	0.998	1.000	3098	tags=18%, list=17%, signal=21%
321	REACTOME_SIGNALLING_TO_RAS		12	-0.32	-0.57	0.974	0.996	1.000	2360	tags=25%, list=13%, signal=29%
322	REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS		10	-0.33	-0.57	0.961	0.994	1.000	5755	tags=70%, list=31%, signal=101%
323	NCI_LPA4-MEDIATED SIGNALING EVENTS		12	-0.28	-0.51	0.993	0.997	1.000	1412	tags=8%, list=8%, signal=9%
324	INOH_ADENYLATE CYCLASE ACTIVATION SIGNALING		11	-0.28	-0.50	0.976	0.995	1.000	1412	tags=9%, list=8%, signal=10%