Details for gene set REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_LMproB.phenotype_transDMproB_versus_LMproB.cls #transDMproB_versus_LMproB
Phenotype	phenotype_transDMproB_versus_LMproB.cls#transDMproB_versus_LMproB
Upregulated in class	LMproB
GeneSet	REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1
Enrichment Score (ES)	-0.7926444
Normalized Enrichment Score (NES)	-1.3950834
Nominal p-value	0.07305936
FDR q-value	1.0
FWER p-Value	1.0

Fig 1: Enrichment plot: REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IQGAP1	6619	4509	0.111	-0.1950	No
2	PRKACB	15140	6459	0.044	-0.2810	No
3	SYT5	17986	6531	0.043	-0.2665	No
4	GNAS	9025 2963 2752	6786	0.038	-0.2639	No
5	RAP1A	8467	6798	0.038	-0.2483	No
6	GCG	14578	6985	0.035	-0.2435	No
7	ABCC8	9941 11649	7711	0.024	-0.2723	No
8	GLP1R	23304	8259	0.017	-0.2946	No
9	PRKAR2B	5288 2107	12603	-0.034	-0.5136	No
10	KCNJ11	17822	13734	-0.057	-0.5499	Yes
11	VAMP2	20826	18251	-1.897	0.0196	Yes

Fig 2: REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1: Random ES distribution
Gene set null distribution of ES for REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1