Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
Upregulated in class | transDMproB |
GeneSet | PROTEIN_KINASE_CASCADE |
Enrichment Score (ES) | 0.5641524 |
Normalized Enrichment Score (NES) | 1.5747374 |
Nominal p-value | 0.0 |
FDR q-value | 0.4405868 |
FWER p-Value | 0.939 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | STAT4 | 14251 9907 | 25 | 9.695 | 0.0282 | Yes | ||
2 | SOCS2 | 5694 | 65 | 8.301 | 0.0514 | Yes | ||
3 | MAPKAPK2 | 13838 | 85 | 7.980 | 0.0747 | Yes | ||
4 | TNFAIP3 | 19810 | 138 | 7.145 | 0.0937 | Yes | ||
5 | MAP3K3 | 20626 | 173 | 6.715 | 0.1123 | Yes | ||
6 | STAT1 | 3936 5524 | 190 | 6.574 | 0.1315 | Yes | ||
7 | LGALS9 | 1441 20332 1200 | 212 | 6.396 | 0.1499 | Yes | ||
8 | CD81 | 8719 | 218 | 6.338 | 0.1689 | Yes | ||
9 | EDG5 | 19216 | 275 | 5.817 | 0.1836 | Yes | ||
10 | SQSTM1 | 9517 | 338 | 5.381 | 0.1967 | Yes | ||
11 | MAP3K11 | 11163 | 339 | 5.379 | 0.2131 | Yes | ||
12 | LITAF | 7149 | 371 | 5.153 | 0.2271 | Yes | ||
13 | MAP3K7IP2 | 19827 | 402 | 4.966 | 0.2406 | Yes | ||
14 | MAPK14 | 23313 | 429 | 4.797 | 0.2539 | Yes | ||
15 | STAT3 | 5525 9906 | 569 | 4.247 | 0.2592 | Yes | ||
16 | DUSP2 | 14865 | 607 | 4.040 | 0.2696 | Yes | ||
17 | MAP4K3 | 22887 | 676 | 3.780 | 0.2774 | Yes | ||
18 | DUSP6 | 19891 3399 | 703 | 3.694 | 0.2872 | Yes | ||
19 | PKN1 | 11567 6799 | 704 | 3.692 | 0.2985 | Yes | ||
20 | RIPK1 | 5381 | 705 | 3.685 | 0.3097 | Yes | ||
21 | CD27 | 16994 | 715 | 3.654 | 0.3204 | Yes | ||
22 | PTEN | 5305 | 722 | 3.641 | 0.3312 | Yes | ||
23 | STAT5A | 20664 | 727 | 3.634 | 0.3420 | Yes | ||
24 | CASP1 | 19577 | 733 | 3.619 | 0.3528 | Yes | ||
25 | CASP8 | 8694 | 770 | 3.525 | 0.3616 | Yes | ||
26 | HCLS1 | 22770 | 781 | 3.509 | 0.3718 | Yes | ||
27 | STK17B | 13957 | 797 | 3.435 | 0.3814 | Yes | ||
28 | LGALS1 | 22429 | 812 | 3.390 | 0.3910 | Yes | ||
29 | IL12A | 4913 | 820 | 3.377 | 0.4009 | Yes | ||
30 | TBK1 | 12137 | 823 | 3.369 | 0.4111 | Yes | ||
31 | TNFSF10 | 15626 | 928 | 3.107 | 0.4149 | Yes | ||
32 | MKNK2 | 3299 9392 | 940 | 3.070 | 0.4237 | Yes | ||
33 | RPS6KA4 | 23804 | 985 | 2.977 | 0.4304 | Yes | ||
34 | TICAM2 | 23440 | 997 | 2.955 | 0.4388 | Yes | ||
35 | MAP4K2 | 6457 | 1046 | 2.839 | 0.4448 | Yes | ||
36 | MARK2 | 8899 | 1127 | 2.668 | 0.4486 | Yes | ||
37 | TRAF6 | 5797 14940 | 1138 | 2.646 | 0.4561 | Yes | ||
38 | NOD1 | 17141 | 1150 | 2.614 | 0.4635 | Yes | ||
39 | STK4 | 14743 | 1158 | 2.598 | 0.4711 | Yes | ||
40 | STAT2 | 19840 | 1162 | 2.593 | 0.4788 | Yes | ||
41 | PIAS1 | 7126 | 1179 | 2.563 | 0.4858 | Yes | ||
42 | TEC | 16514 | 1209 | 2.517 | 0.4919 | Yes | ||
43 | CXCR4 | 13844 | 1216 | 2.505 | 0.4992 | Yes | ||
44 | MAPK9 | 1233 20903 1383 | 1236 | 2.449 | 0.5056 | Yes | ||
45 | MAP4K4 | 11241 | 1329 | 2.268 | 0.5075 | Yes | ||
46 | SCOTIN | 3136 19299 3102 | 1337 | 2.252 | 0.5140 | Yes | ||
47 | ICK | 7135 12146 | 1436 | 2.087 | 0.5150 | Yes | ||
48 | TSPAN6 | 2616 24068 | 1497 | 1.999 | 0.5179 | Yes | ||
49 | CRKL | 4560 | 1532 | 1.945 | 0.5220 | Yes | ||
50 | STAMBP | 17097 | 1579 | 1.887 | 0.5252 | Yes | ||
51 | BST2 | 18845 | 1597 | 1.868 | 0.5300 | Yes | ||
52 | RELA | 23783 | 1612 | 1.845 | 0.5348 | Yes | ||
53 | GPS2 | 12096 | 1644 | 1.794 | 0.5386 | Yes | ||
54 | PPM1A | 5279 9607 | 1673 | 1.756 | 0.5425 | Yes | ||
55 | CCM2 | 20950 | 1675 | 1.754 | 0.5478 | Yes | ||
56 | MAP3K5 | 20079 11166 | 1721 | 1.701 | 0.5505 | Yes | ||
57 | SOCS3 | 20131 | 1779 | 1.638 | 0.5524 | Yes | ||
58 | SOD1 | 9846 | 1815 | 1.620 | 0.5554 | Yes | ||
59 | SLC20A1 | 14855 | 1856 | 1.563 | 0.5580 | Yes | ||
60 | EGF | 15169 | 2044 | 1.359 | 0.5520 | Yes | ||
61 | BIRC2 | 4397 4398 | 2142 | 1.276 | 0.5506 | Yes | ||
62 | MAP3K4 | 23126 | 2216 | 1.200 | 0.5503 | Yes | ||
63 | IKBKE | 67 | 2279 | 1.135 | 0.5504 | Yes | ||
64 | TRAF2 | 14657 | 2284 | 1.132 | 0.5536 | Yes | ||
65 | OTUD7B | 10483 | 2295 | 1.122 | 0.5565 | Yes | ||
66 | NDFIP2 | 21941 | 2354 | 1.078 | 0.5566 | Yes | ||
67 | WNK1 | 1109 17020 6106 | 2404 | 1.026 | 0.5571 | Yes | ||
68 | MAP3K7IP1 | 2193 2171 22419 | 2426 | 1.011 | 0.5590 | Yes | ||
69 | FGF13 | 4720 8963 2627 | 2430 | 1.006 | 0.5619 | Yes | ||
70 | SH2D3C | 2864 | 2446 | 1.000 | 0.5642 | Yes | ||
71 | FKBP1A | 2801 | 2522 | 0.945 | 0.5630 | No | ||
72 | HIPK2 | 17180 | 2574 | 0.899 | 0.5629 | No | ||
73 | CAMKK2 | 9870 | 2712 | 0.776 | 0.5578 | No | ||
74 | ATP2C1 | 10660 6178 | 2730 | 0.759 | 0.5592 | No | ||
75 | PAK1 | 9527 | 2767 | 0.720 | 0.5595 | No | ||
76 | UBE2N | 8216 19898 | 2919 | 0.603 | 0.5531 | No | ||
77 | MAP3K7 | 16255 | 2925 | 0.600 | 0.5546 | No | ||
78 | MAST1 | 12143 | 2942 | 0.590 | 0.5556 | No | ||
79 | MAPK13 | 23314 | 3119 | 0.491 | 0.5475 | No | ||
80 | NF1 | 5165 | 3151 | 0.469 | 0.5472 | No | ||
81 | GJA1 | 20023 | 3216 | 0.444 | 0.5451 | No | ||
82 | SNF1LK2 | 6168 10649 | 3260 | 0.419 | 0.5440 | No | ||
83 | IFNAR2 | 22705 1699 | 3380 | 0.366 | 0.5387 | No | ||
84 | MAPK8IP3 | 11402 23080 | 3412 | 0.354 | 0.5381 | No | ||
85 | NOD2 | 6384 | 3419 | 0.353 | 0.5388 | No | ||
86 | MAP4K5 | 11853 21048 2101 2142 | 3458 | 0.336 | 0.5378 | No | ||
87 | ECM1 | 15246 1892 | 3534 | 0.307 | 0.5346 | No | ||
88 | F2 | 14524 | 3610 | 0.281 | 0.5314 | No | ||
89 | FYB | 10717 | 3715 | 0.252 | 0.5265 | No | ||
90 | EEF1D | 12393 2309 | 3802 | 0.229 | 0.5225 | No | ||
91 | TLR6 | 215 16528 | 3864 | 0.215 | 0.5199 | No | ||
92 | MADD | 2926 14526 | 3877 | 0.213 | 0.5199 | No | ||
93 | EDG2 | 9033 | 3879 | 0.213 | 0.5205 | No | ||
94 | GHRL | 1183 17040 | 3899 | 0.204 | 0.5200 | No | ||
95 | MAP3K10 | 3831 17916 | 3901 | 0.204 | 0.5206 | No | ||
96 | FPR1 | 23115 | 4067 | 0.169 | 0.5121 | No | ||
97 | DUSP4 | 18632 3820 | 4129 | 0.160 | 0.5093 | No | ||
98 | STK3 | 7084 | 4281 | 0.137 | 0.5015 | No | ||
99 | TPD52L1 | 3420 19793 | 4343 | 0.128 | 0.4986 | No | ||
100 | CLCF1 | 12160 3742 | 4347 | 0.127 | 0.4988 | No | ||
101 | NMI | 14590 | 4369 | 0.123 | 0.4980 | No | ||
102 | PRDX4 | 24026 | 4392 | 0.120 | 0.4972 | No | ||
103 | DAXX | 23290 | 4398 | 0.119 | 0.4973 | No | ||
104 | IFNAR1 | 22703 | 4428 | 0.116 | 0.4961 | No | ||
105 | HGS | 20568 | 4594 | 0.096 | 0.4874 | No | ||
106 | PROK2 | 17057 | 4611 | 0.095 | 0.4868 | No | ||
107 | MAP3K6 | 16054 | 4631 | 0.093 | 0.4860 | No | ||
108 | TNFSF14 | 1584 22914 | 4636 | 0.092 | 0.4861 | No | ||
109 | BCL10 | 15397 | 4641 | 0.092 | 0.4862 | No | ||
110 | CCL2 | 9788 | 4849 | 0.076 | 0.4751 | No | ||
111 | PINK1 | 12752 15703 | 4870 | 0.075 | 0.4743 | No | ||
112 | TNFRSF10B | 21971 10205 5781 10204 | 4956 | 0.070 | 0.4699 | No | ||
113 | ECT2 | 15367 | 4978 | 0.069 | 0.4689 | No | ||
114 | LTBR | 16993 | 5004 | 0.068 | 0.4678 | No | ||
115 | RGS3 | 2434 2474 6937 11935 2374 2332 2445 2390 | 5251 | 0.056 | 0.4546 | No | ||
116 | NDFIP1 | 23573 | 5258 | 0.056 | 0.4544 | No | ||
117 | TRIP6 | 16331 | 5413 | 0.049 | 0.4462 | No | ||
118 | ADRA1A | 2850 8560 | 5439 | 0.048 | 0.4450 | No | ||
119 | IL20 | 13840 | 5637 | 0.042 | 0.4344 | No | ||
120 | ADORA2B | 20850 | 5762 | 0.039 | 0.4277 | No | ||
121 | ITGB1BP1 | 9189 | 5789 | 0.038 | 0.4264 | No | ||
122 | MAP3K2 | 11165 | 6025 | 0.032 | 0.4137 | No | ||
123 | NF2 | 1222 5166 | 6028 | 0.032 | 0.4137 | No | ||
124 | EPGN | 16798 | 6036 | 0.032 | 0.4134 | No | ||
125 | RHOC | 15467 | 6117 | 0.030 | 0.4092 | No | ||
126 | ADRB3 | 18901 | 6142 | 0.030 | 0.4080 | No | ||
127 | DUSP9 | 24307 | 6160 | 0.029 | 0.4071 | No | ||
128 | ERC1 | 1013 17021 995 1136 | 6369 | 0.025 | 0.3959 | No | ||
129 | C5AR1 | 17957 | 6374 | 0.025 | 0.3957 | No | ||
130 | DUSP16 | 1004 7699 | 6387 | 0.025 | 0.3952 | No | ||
131 | RIPK2 | 2528 15935 | 6494 | 0.023 | 0.3895 | No | ||
132 | STK38 | 23045 | 6636 | 0.020 | 0.3818 | No | ||
133 | MAP3K9 | 6872 | 6656 | 0.019 | 0.3809 | No | ||
134 | SPRED2 | 8539 4332 | 6750 | 0.018 | 0.3759 | No | ||
135 | SOCS6 | 12042 7044 | 6788 | 0.017 | 0.3739 | No | ||
136 | MINK1 | 20802 | 6976 | 0.014 | 0.3638 | No | ||
137 | LYN | 16281 | 7117 | 0.012 | 0.3562 | No | ||
138 | TNFSF15 | 15863 | 7290 | 0.009 | 0.3468 | No | ||
139 | DAPK1 | 7632 | 7345 | 0.009 | 0.3439 | No | ||
140 | EDA2R | 6364 | 7369 | 0.008 | 0.3427 | No | ||
141 | DUSP22 | 466 21680 | 7585 | 0.005 | 0.3310 | No | ||
142 | GNG3 | 23752 | 7624 | 0.005 | 0.3290 | No | ||
143 | FASLG | 13789 | 7673 | 0.004 | 0.3264 | No | ||
144 | CARD10 | 22214 8376 | 7890 | 0.001 | 0.3146 | No | ||
145 | TRIM13 | 7313 | 8108 | -0.001 | 0.3028 | No | ||
146 | FGFR1 | 3789 8968 | 8129 | -0.002 | 0.3017 | No | ||
147 | RPS6KA2 | 9759 9758 | 8473 | -0.006 | 0.2831 | No | ||
148 | IRAK1BP1 | 19367 | 8536 | -0.007 | 0.2797 | No | ||
149 | RPS6KA5 | 2076 21005 | 8560 | -0.007 | 0.2785 | No | ||
150 | STAT5B | 20222 | 8729 | -0.010 | 0.2694 | No | ||
151 | MBIP | 21063 2072 | 8942 | -0.013 | 0.2579 | No | ||
152 | CFLAR | 8738 4517 | 9126 | -0.016 | 0.2479 | No | ||
153 | SHC1 | 9813 9812 5430 | 9137 | -0.016 | 0.2474 | No | ||
154 | CANT1 | 13304 | 9398 | -0.019 | 0.2334 | No | ||
155 | FYN | 3375 3395 20052 | 9588 | -0.022 | 0.2231 | No | ||
156 | CCR2 | 19250 | 9759 | -0.024 | 0.2139 | No | ||
157 | SCG2 | 5410 14425 | 9813 | -0.026 | 0.2111 | No | ||
158 | TDGF1 | 5704 10108 | 9873 | -0.026 | 0.2080 | No | ||
159 | PLCE1 | 13156 | 9884 | -0.027 | 0.2075 | No | ||
160 | WNK3 | 24227 | 9894 | -0.027 | 0.2071 | No | ||
161 | TAOK2 | 10610 3794 | 9987 | -0.028 | 0.2022 | No | ||
162 | RPL17 | 11429 6653 | 10174 | -0.031 | 0.1922 | No | ||
163 | TGFA | 17381 | 10239 | -0.033 | 0.1888 | No | ||
164 | IL31RA | 21347 | 10276 | -0.033 | 0.1869 | No | ||
165 | IKBKG | 2570 2562 4908 | 10350 | -0.035 | 0.1831 | No | ||
166 | SGK2 | 14750 | 10523 | -0.037 | 0.1738 | No | ||
167 | NEK6 | 15018 | 10592 | -0.039 | 0.1702 | No | ||
168 | SRC | 5507 | 11343 | -0.054 | 0.1296 | No | ||
169 | MDFI | 22950 | 11478 | -0.057 | 0.1225 | No | ||
170 | HTR2B | 13900 | 11490 | -0.057 | 0.1220 | No | ||
171 | MAP2K7 | 6453 | 11507 | -0.057 | 0.1213 | No | ||
172 | WNK4 | 7644 | 11521 | -0.058 | 0.1208 | No | ||
173 | ADRA1B | 4354 | 11547 | -0.058 | 0.1196 | No | ||
174 | CXXC5 | 12523 | 11557 | -0.059 | 0.1193 | No | ||
175 | RHOH | 13226 | 11703 | -0.063 | 0.1116 | No | ||
176 | ADRA2A | 4355 | 11707 | -0.063 | 0.1116 | No | ||
177 | LATS2 | 11923 6928 | 11843 | -0.067 | 0.1045 | No | ||
178 | MAP3K13 | 22814 | 11925 | -0.070 | 0.1003 | No | ||
179 | CHRNA7 | 17808 | 11973 | -0.071 | 0.0980 | No | ||
180 | STK38L | 17240 | 12059 | -0.074 | 0.0936 | No | ||
181 | FGFR3 | 8969 3566 | 12064 | -0.074 | 0.0936 | No | ||
182 | CD40 | 10207 2961 2968 5783 | 12161 | -0.078 | 0.0886 | No | ||
183 | RGS4 | 9724 | 12379 | -0.088 | 0.0770 | No | ||
184 | NEK11 | 3099 19016 | 12418 | -0.090 | 0.0752 | No | ||
185 | DUSP10 | 4003 14016 | 12469 | -0.092 | 0.0728 | No | ||
186 | NLK | 5179 5178 | 12596 | -0.097 | 0.0662 | No | ||
187 | PRKAG3 | 6295 | 12725 | -0.103 | 0.0596 | No | ||
188 | MAPK8IP2 | 77 | 12884 | -0.112 | 0.0513 | No | ||
189 | FGF2 | 15608 | 13012 | -0.120 | 0.0448 | No | ||
190 | ATP6AP2 | 2567 24380 2579 2656 | 13029 | -0.121 | 0.0443 | No | ||
191 | IL22RA2 | 20082 | 13229 | -0.134 | 0.0339 | No | ||
192 | RHOA | 8624 4409 4410 | 13287 | -0.138 | 0.0312 | No | ||
193 | CARTPT | 21374 | 13342 | -0.142 | 0.0287 | No | ||
194 | NRTN | 22923 | 13352 | -0.142 | 0.0286 | No | ||
195 | GPS1 | 1392 9943 5550 9944 | 13481 | -0.154 | 0.0221 | No | ||
196 | MARK1 | 5955 | 13503 | -0.156 | 0.0214 | No | ||
197 | MAPK10 | 11169 | 13518 | -0.157 | 0.0212 | No | ||
198 | EDARADD | 5056 3282 3278 | 13701 | -0.174 | 0.0118 | No | ||
199 | MAPK11 | 2264 9618 22163 | 14126 | -0.222 | -0.0106 | No | ||
200 | TNFRSF1A | 1181 10206 | 14170 | -0.228 | -0.0123 | No | ||
201 | SRPK2 | 5513 | 14351 | -0.255 | -0.0213 | No | ||
202 | IRAK2 | 17324 | 14387 | -0.261 | -0.0224 | No | ||
203 | SECTM1 | 20104 | 14562 | -0.295 | -0.0310 | No | ||
204 | GRM4 | 332 | 14578 | -0.301 | -0.0309 | No | ||
205 | REL | 9716 | 14615 | -0.310 | -0.0319 | No | ||
206 | AKAP11 | 2695 | 14944 | -0.400 | -0.0485 | No | ||
207 | DUSP8 | 9493 | 15094 | -0.452 | -0.0552 | No | ||
208 | MAP3K12 | 6454 11164 | 15238 | -0.509 | -0.0615 | No | ||
209 | TRAF7 | 10325 | 15315 | -0.542 | -0.0640 | No | ||
210 | SPRED1 | 4331 | 15415 | -0.601 | -0.0675 | No | ||
211 | MKNK1 | 2504 | 15608 | -0.715 | -0.0758 | No | ||
212 | PLK2 | 21566 | 15617 | -0.721 | -0.0740 | No | ||
213 | MAP2K4 | 20405 | 15684 | -0.770 | -0.0753 | No | ||
214 | MYD88 | 18970 | 15820 | -0.874 | -0.0800 | No | ||
215 | SNF1LK | 23033 | 15841 | -0.887 | -0.0783 | No | ||
216 | GADD45G | 21637 | 15858 | -0.901 | -0.0765 | No | ||
217 | FAF1 | 2508 16137 8951 | 16001 | -1.000 | -0.0811 | No | ||
218 | HMOX1 | 18565 | 16022 | -1.007 | -0.0791 | No | ||
219 | NUP62 | 9497 | 16051 | -1.023 | -0.0776 | No | ||
220 | GSG2 | 20356 | 16111 | -1.065 | -0.0775 | No | ||
221 | ADRB2 | 23422 | 16221 | -1.155 | -0.0799 | No | ||
222 | F2R | 21386 | 16286 | -1.215 | -0.0797 | No | ||
223 | PPP5C | 17952 | 16344 | -1.271 | -0.0789 | No | ||
224 | FLNA | 24129 | 16418 | -1.351 | -0.0788 | No | ||
225 | MAPK8 | 6459 | 16452 | -1.403 | -0.0763 | No | ||
226 | IRAK1 | 4916 | 16503 | -1.465 | -0.0746 | No | ||
227 | DAPK2 | 19395 | 16630 | -1.575 | -0.0766 | No | ||
228 | MALT1 | 6274 | 16663 | -1.599 | -0.0735 | No | ||
229 | ZDHHC13 | 18233 1936 | 16676 | -1.613 | -0.0692 | No | ||
230 | BLK | 3205 21791 | 16677 | -1.613 | -0.0643 | No | ||
231 | GADD45B | 19935 | 16692 | -1.625 | -0.0601 | No | ||
232 | ADAM9 | 18910 | 16723 | -1.658 | -0.0567 | No | ||
233 | BCL3 | 8654 | 16826 | -1.782 | -0.0568 | No | ||
234 | UBE2V1 | 12381 | 16869 | -1.839 | -0.0535 | No | ||
235 | DAPK3 | 19932 | 16909 | -1.903 | -0.0498 | No | ||
236 | SOCS1 | 4522 | 17035 | -2.077 | -0.0502 | No | ||
237 | VAPA | 22908 | 17060 | -2.112 | -0.0451 | No | ||
238 | DBNL | 20954 | 17176 | -2.255 | -0.0445 | No | ||
239 | CHUK | 23665 | 17633 | -3.139 | -0.0597 | No | ||
240 | FADD | 17536 8950 4711 | 17838 | -3.671 | -0.0596 | No | ||
241 | TRAF5 | 13718 | 17884 | -3.811 | -0.0505 | No | ||
242 | CD24 | 8711 | 17973 | -4.116 | -0.0427 | No | ||
243 | SRPK1 | 23049 | 18064 | -4.455 | -0.0340 | No | ||
244 | PIK3CB | 19030 | 18080 | -4.515 | -0.0211 | No | ||
245 | ADRA2C | 16869 | 18177 | -4.885 | -0.0114 | No | ||
246 | GPR89A | 7459 12548 | 18370 | -5.760 | -0.0043 | No | ||
247 | MAP4K1 | 18313 | 18371 | -5.767 | 0.0133 | No |