Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
Upregulated in class | DMpreB |
GeneSet | V$E2F1_Q6_01 |
Enrichment Score (ES) | -0.4663413 |
Normalized Enrichment Score (NES) | -1.2342453 |
Nominal p-value | 0.04563492 |
FDR q-value | 0.6713987 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | GPRC5B | 17662 | 148 | 7.065 | 0.0279 | No | ||
2 | MXD3 | 21455 | 274 | 5.817 | 0.0507 | No | ||
3 | RAB11B | 9676 | 558 | 4.276 | 0.0571 | No | ||
4 | HIST1H2BK | 11423 | 563 | 4.269 | 0.0786 | No | ||
5 | CTCF | 18490 | 838 | 3.339 | 0.0808 | No | ||
6 | CASP2 | 8692 | 1012 | 2.909 | 0.0862 | No | ||
7 | FHOD1 | 18772 | 1084 | 2.741 | 0.0963 | No | ||
8 | SLC25A1 | 22645 | 1200 | 2.530 | 0.1029 | No | ||
9 | AK2 | 8563 2479 16073 | 1221 | 2.493 | 0.1145 | No | ||
10 | PPM1D | 20721 | 1407 | 2.132 | 0.1153 | No | ||
11 | NUMA1 | 18167 | 1463 | 2.043 | 0.1227 | No | ||
12 | USP52 | 3397 19841 | 1516 | 1.974 | 0.1299 | No | ||
13 | PIK3CD | 9563 | 1550 | 1.916 | 0.1379 | No | ||
14 | TRIM39 | 22994 | 1585 | 1.878 | 0.1456 | No | ||
15 | RBL1 | 14373 | 1624 | 1.826 | 0.1528 | No | ||
16 | KLF5 | 4456 | 1663 | 1.774 | 0.1598 | No | ||
17 | POLD3 | 17742 | 1682 | 1.745 | 0.1677 | No | ||
18 | MCM4 | 22655 1708 | 1971 | 1.440 | 0.1594 | No | ||
19 | DNMT1 | 19217 | 2021 | 1.379 | 0.1638 | No | ||
20 | PTMA | 9657 | 2030 | 1.375 | 0.1703 | No | ||
21 | ILF3 | 3110 3030 9176 | 2324 | 1.096 | 0.1600 | No | ||
22 | ATE1 | 388 17602 | 2342 | 1.083 | 0.1646 | No | ||
23 | CCNT1 | 22140 11607 | 2349 | 1.081 | 0.1698 | No | ||
24 | RANBP1 | 9692 5357 | 2445 | 1.000 | 0.1697 | No | ||
25 | HMGN2 | 9095 | 2587 | 0.887 | 0.1666 | No | ||
26 | BRMS1L | 21268 | 2596 | 0.877 | 0.1706 | No | ||
27 | USP2 | 19480 3052 3043 | 2862 | 0.641 | 0.1595 | No | ||
28 | FLI1 | 4729 | 2909 | 0.609 | 0.1601 | No | ||
29 | HIST1H2AH | 11414 | 3027 | 0.541 | 0.1565 | No | ||
30 | MYC | 22465 9435 | 3045 | 0.531 | 0.1583 | No | ||
31 | TBX6 | 1993 18075 | 3155 | 0.467 | 0.1548 | No | ||
32 | SP1 | 9852 | 3303 | 0.399 | 0.1489 | No | ||
33 | SYNCRIP | 3078 3035 3107 | 3530 | 0.309 | 0.1382 | No | ||
34 | ERF | 4680 8914 | 3707 | 0.255 | 0.1299 | No | ||
35 | POU2F1 | 5275 3989 4065 4010 | 3742 | 0.245 | 0.1293 | No | ||
36 | MYH10 | 8077 | 3920 | 0.200 | 0.1208 | No | ||
37 | TMPO | 5778 | 3964 | 0.188 | 0.1194 | No | ||
38 | PHF15 | 20467 8050 | 3986 | 0.184 | 0.1192 | No | ||
39 | FKBP5 | 23051 | 4174 | 0.151 | 0.1098 | No | ||
40 | TNF | 23004 | 4390 | 0.120 | 0.0988 | No | ||
41 | PRKDC | 9617 22847 | 4504 | 0.107 | 0.0932 | No | ||
42 | ARHGAP6 | 24207 | 4626 | 0.093 | 0.0871 | No | ||
43 | ERBB2IP | 3232 12234 | 4690 | 0.088 | 0.0842 | No | ||
44 | HNRPUL1 | 6118 17923 1608 10577 1345 | 4730 | 0.084 | 0.0825 | No | ||
45 | SPHK2 | 1217 1806 12155 | 4850 | 0.076 | 0.0764 | No | ||
46 | STAG1 | 5520 9905 2987 | 4970 | 0.069 | 0.0703 | No | ||
47 | ADAMTS2 | 5706 20899 1356 | 5307 | 0.054 | 0.0524 | No | ||
48 | GNG4 | 21706 | 5348 | 0.052 | 0.0505 | No | ||
49 | DNAJC9 | 21912 | 5400 | 0.050 | 0.0480 | No | ||
50 | DHH | 4629 | 6114 | 0.030 | 0.0095 | No | ||
51 | MGAT2 | 21256 | 6153 | 0.029 | 0.0076 | No | ||
52 | CBX5 | 22108 4485 | 6228 | 0.028 | 0.0037 | No | ||
53 | ORC1L | 327 16144 | 6252 | 0.027 | 0.0026 | No | ||
54 | STK35 | 14851 | 6327 | 0.026 | -0.0012 | No | ||
55 | DDB2 | 2721 2878 14525 2661 | 6512 | 0.022 | -0.0111 | No | ||
56 | HNRPR | 13196 7909 2500 | 6617 | 0.020 | -0.0166 | No | ||
57 | FZD1 | 16923 | 6622 | 0.020 | -0.0168 | No | ||
58 | ATM | 2976 19115 | 6719 | 0.018 | -0.0219 | No | ||
59 | MCM6 | 4000 13845 4119 | 7085 | 0.013 | -0.0416 | No | ||
60 | FBXO5 | 19830 | 7147 | 0.012 | -0.0448 | No | ||
61 | HNRPD | 8645 | 7181 | 0.011 | -0.0465 | No | ||
62 | BMP2 | 14833 | 7661 | 0.004 | -0.0725 | No | ||
63 | ATAD2 | 2268 2256 | 7798 | 0.003 | -0.0798 | No | ||
64 | MTSS1 | 5585 22285 | 7799 | 0.003 | -0.0798 | No | ||
65 | CASP8AP2 | 16253 | 7858 | 0.002 | -0.0830 | No | ||
66 | POLE2 | 21053 | 7971 | 0.000 | -0.0890 | No | ||
67 | NPAT | 19452 6356 | 8038 | -0.000 | -0.0926 | No | ||
68 | KCNS2 | 4949 2232 | 8148 | -0.002 | -0.0985 | No | ||
69 | EZH2 | 1092 17163 | 8583 | -0.008 | -0.1220 | No | ||
70 | FANCG | 15904 | 9016 | -0.014 | -0.1453 | No | ||
71 | HNRPA1 | 9103 4860 | 9192 | -0.016 | -0.1547 | No | ||
72 | CDC45L | 22642 1752 | 9842 | -0.026 | -0.1897 | No | ||
73 | SYT6 | 13437 7042 12040 | 9929 | -0.027 | -0.1942 | No | ||
74 | TNFRSF19L | 11498 6727 6726 | 10037 | -0.029 | -0.1999 | No | ||
75 | PAX6 | 5223 | 10064 | -0.030 | -0.2011 | No | ||
76 | REPS2 | 24018 | 10743 | -0.041 | -0.2377 | No | ||
77 | HR | 3622 9119 | 11074 | -0.048 | -0.2553 | No | ||
78 | PCSK1 | 21600 | 11208 | -0.051 | -0.2622 | No | ||
79 | IPO7 | 6130 | 11240 | -0.051 | -0.2637 | No | ||
80 | PODN | 15811 | 11347 | -0.054 | -0.2691 | No | ||
81 | HCN3 | 4843 1763 | 11574 | -0.059 | -0.2811 | No | ||
82 | RB1CC1 | 4486 14299 | 11599 | -0.060 | -0.2821 | No | ||
83 | RPL18 | 450 5390 | 11693 | -0.062 | -0.2868 | No | ||
84 | MAZ | 1327 17623 | 11744 | -0.064 | -0.2892 | No | ||
85 | TOPBP1 | 10659 | 11806 | -0.066 | -0.2922 | No | ||
86 | TYRO3 | 5811 | 12031 | -0.073 | -0.3039 | No | ||
87 | IRX3 | 18793 | 12081 | -0.075 | -0.3062 | No | ||
88 | SMARCA1 | 24165 | 12455 | -0.091 | -0.3259 | No | ||
89 | ASXL2 | 7957 | 13430 | -0.149 | -0.3779 | No | ||
90 | CNOT3 | 6112 10565 6113 | 13761 | -0.182 | -0.3949 | No | ||
91 | WEE1 | 18127 | 13796 | -0.184 | -0.3958 | No | ||
92 | SFRS1 | 8492 | 13847 | -0.190 | -0.3975 | No | ||
93 | HMGA2 | 4857 9098 3341 3444 | 13863 | -0.191 | -0.3974 | No | ||
94 | EFNA5 | 4655 8884 | 13865 | -0.191 | -0.3965 | No | ||
95 | ACTN3 | 23967 8540 | 14038 | -0.211 | -0.4047 | No | ||
96 | SYNGR4 | 17825 | 14083 | -0.217 | -0.4060 | No | ||
97 | MCM8 | 14834 | 14090 | -0.218 | -0.4052 | No | ||
98 | PCDH10 | 5227 9534 1893 | 14142 | -0.225 | -0.4068 | No | ||
99 | HOXC10 | 22342 | 14164 | -0.228 | -0.4068 | No | ||
100 | RAD51 | 2897 14903 | 14202 | -0.234 | -0.4076 | No | ||
101 | NCOA6 | 2876 14382 | 14241 | -0.239 | -0.4085 | No | ||
102 | PCNA | 9535 | 14386 | -0.261 | -0.4149 | No | ||
103 | GATA1 | 24196 | 14447 | -0.272 | -0.4168 | No | ||
104 | STAG2 | 5521 | 14608 | -0.308 | -0.4239 | No | ||
105 | YBX2 | 20818 | 14693 | -0.330 | -0.4268 | No | ||
106 | SIN3A | 5442 | 14813 | -0.359 | -0.4314 | No | ||
107 | SFRS2 | 9807 20136 | 14825 | -0.363 | -0.4302 | No | ||
108 | NCL | 5153 13899 | 14974 | -0.407 | -0.4361 | No | ||
109 | LRP1 | 9284 | 15017 | -0.419 | -0.4362 | No | ||
110 | PAQR4 | 23105 | 15316 | -0.542 | -0.4496 | No | ||
111 | AP4M1 | 3499 16656 | 15528 | -0.668 | -0.4577 | No | ||
112 | PHF13 | 15659 | 15689 | -0.776 | -0.4624 | Yes | ||
113 | CHD4 | 8418 17281 4225 | 15754 | -0.826 | -0.4617 | Yes | ||
114 | JPH1 | 13994 | 15826 | -0.877 | -0.4611 | Yes | ||
115 | ENPP1 | 19804 | 15834 | -0.885 | -0.4569 | Yes | ||
116 | STMN1 | 9261 | 15852 | -0.895 | -0.4533 | Yes | ||
117 | CLSPN | 16079 11256 6530 | 15978 | -0.994 | -0.4550 | Yes | ||
118 | UXT | 5837 10267 | 15988 | -0.997 | -0.4504 | Yes | ||
119 | FAF1 | 2508 16137 8951 | 16001 | -1.000 | -0.4460 | Yes | ||
120 | E2F3 | 21500 8874 | 16104 | -1.060 | -0.4461 | Yes | ||
121 | ACBD6 | 14089 | 16174 | -1.113 | -0.4442 | Yes | ||
122 | AMD1 | 8583 | 16377 | -1.303 | -0.4485 | Yes | ||
123 | FANCC | 4712 | 16538 | -1.502 | -0.4496 | Yes | ||
124 | UFD1L | 22825 | 16559 | -1.518 | -0.4429 | Yes | ||
125 | ATP5G2 | 12610 | 16579 | -1.540 | -0.4361 | Yes | ||
126 | DNAJC11 | 2486 6068 | 16583 | -1.541 | -0.4285 | Yes | ||
127 | CDC5L | 7746 7745 7744 | 16589 | -1.544 | -0.4209 | Yes | ||
128 | USP37 | 13923 | 16661 | -1.597 | -0.4166 | Yes | ||
129 | GADD45B | 19935 | 16692 | -1.625 | -0.4100 | Yes | ||
130 | CDCA7 | 12437 | 16925 | -1.927 | -0.4127 | Yes | ||
131 | INSM1 | 14815 | 16954 | -1.964 | -0.4043 | Yes | ||
132 | AP1S1 | 3500 3453 16335 | 16979 | -1.997 | -0.3954 | Yes | ||
133 | ACO2 | 8527 | 17017 | -2.055 | -0.3870 | Yes | ||
134 | MCM2 | 17074 | 17133 | -2.214 | -0.3819 | Yes | ||
135 | PRPS1 | 24233 | 17165 | -2.238 | -0.3722 | Yes | ||
136 | EED | 17759 | 17174 | -2.248 | -0.3612 | Yes | ||
137 | SUMO1 | 5826 3943 10247 | 17274 | -2.466 | -0.3541 | Yes | ||
138 | CDC25A | 8721 | 17285 | -2.488 | -0.3419 | Yes | ||
139 | SLC9A7 | 24177 | 17326 | -2.578 | -0.3310 | Yes | ||
140 | E2F1 | 14384 | 17346 | -2.611 | -0.3188 | Yes | ||
141 | RQCD1 | 12205 | 17366 | -2.645 | -0.3063 | Yes | ||
142 | MSH2 | 23138 | 17476 | -2.856 | -0.2977 | Yes | ||
143 | HTF9C | 4886 1678 | 17479 | -2.864 | -0.2833 | Yes | ||
144 | RPS19 | 5398 | 17490 | -2.882 | -0.2691 | Yes | ||
145 | PHF5A | 22194 | 17601 | -3.077 | -0.2595 | Yes | ||
146 | GMNN | 21513 | 17632 | -3.131 | -0.2452 | Yes | ||
147 | MCM3 | 13991 | 17716 | -3.357 | -0.2326 | Yes | ||
148 | NASP | 2383 2387 6955 | 17728 | -3.387 | -0.2160 | Yes | ||
149 | SUV39H1 | 24194 | 17743 | -3.415 | -0.1993 | Yes | ||
150 | POLA2 | 23988 | 17757 | -3.452 | -0.1825 | Yes | ||
151 | GSPT1 | 9046 | 17814 | -3.603 | -0.1672 | Yes | ||
152 | HIRA | 4852 9090 | 18002 | -4.201 | -0.1560 | Yes | ||
153 | MRPL40 | 22641 | 18062 | -4.439 | -0.1366 | Yes | ||
154 | UNG | 10257 16744 | 18161 | -4.819 | -0.1174 | Yes | ||
155 | PPP1R8 | 15730 | 18190 | -4.937 | -0.0938 | Yes | ||
156 | MCM7 | 9372 3568 | 18211 | -4.973 | -0.0696 | Yes | ||
157 | MAP4K1 | 18313 | 18371 | -5.767 | -0.0489 | Yes | ||
158 | NOLC1 | 7704 | 18389 | -5.942 | -0.0196 | Yes | ||
159 | PPRC1 | 23808 | 18439 | -6.263 | 0.0096 | Yes |