Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
| Upregulated in class | transDMproB |
| GeneSet | TCRPATHWAY |
| Enrichment Score (ES) | 0.71467155 |
| Normalized Enrichment Score (NES) | 1.6202532 |
| Nominal p-value | 0.004338395 |
| FDR q-value | 0.13074559 |
| FWER p-Value | 0.433 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LAT | 17643 | 116 | 7.434 | 0.1223 | Yes | ||
| 2 | VAV1 | 23173 | 347 | 5.300 | 0.2016 | Yes | ||
| 3 | PTPN7 | 11500 | 659 | 3.836 | 0.2512 | Yes | ||
| 4 | LCK | 15746 | 786 | 3.491 | 0.3048 | Yes | ||
| 5 | RASA1 | 10174 | 860 | 3.276 | 0.3576 | Yes | ||
| 6 | CALM3 | 8682 | 1025 | 2.875 | 0.3985 | Yes | ||
| 7 | PPP3CC | 21763 | 1270 | 2.374 | 0.4264 | Yes | ||
| 8 | MAP3K1 | 21348 | 1355 | 2.218 | 0.4603 | Yes | ||
| 9 | PPP3CB | 5285 | 1370 | 2.196 | 0.4975 | Yes | ||
| 10 | NFATC3 | 5169 | 1511 | 1.983 | 0.5243 | Yes | ||
| 11 | GRB2 | 20149 | 1534 | 1.943 | 0.5567 | Yes | ||
| 12 | NFKB1 | 15160 | 1611 | 1.847 | 0.5845 | Yes | ||
| 13 | RELA | 23783 | 1612 | 1.845 | 0.6164 | Yes | ||
| 14 | JUN | 15832 | 1670 | 1.759 | 0.6438 | Yes | ||
| 15 | PRKCB1 | 1693 9574 | 1709 | 1.712 | 0.6714 | Yes | ||
| 16 | CALM2 | 8681 | 1832 | 1.596 | 0.6924 | Yes | ||
| 17 | NFATC1 | 23398 1999 5167 9455 1985 1957 | 2476 | 0.992 | 0.6749 | Yes | ||
| 18 | RAC1 | 16302 | 2500 | 0.969 | 0.6905 | Yes | ||
| 19 | MAPK3 | 6458 11170 | 2529 | 0.941 | 0.7053 | Yes | ||
| 20 | FOS | 21202 | 2723 | 0.766 | 0.7081 | Yes | ||
| 21 | RAF1 | 17035 | 2978 | 0.564 | 0.7042 | Yes | ||
| 22 | CD3D | 19473 | 3103 | 0.500 | 0.7062 | Yes | ||
| 23 | MAP2K1 | 19082 | 3106 | 0.498 | 0.7147 | Yes | ||
| 24 | ZAP70 | 14271 4042 | 4655 | 0.091 | 0.6329 | No | ||
| 25 | SOS1 | 5476 | 4708 | 0.086 | 0.6316 | No | ||
| 26 | CD3G | 19139 | 4851 | 0.076 | 0.6253 | No | ||
| 27 | PIK3R1 | 3170 | 4927 | 0.072 | 0.6225 | No | ||
| 28 | PLCG1 | 14753 | 7414 | 0.008 | 0.4887 | No | ||
| 29 | PIK3CA | 9562 | 7760 | 0.003 | 0.4702 | No | ||
| 30 | SYT1 | 5565 | 7856 | 0.002 | 0.4651 | No | ||
| 31 | CD3E | 8714 | 8819 | -0.011 | 0.4135 | No | ||
| 32 | SHC1 | 9813 9812 5430 | 9137 | -0.016 | 0.3967 | No | ||
| 33 | NFATC2 | 5168 2866 | 9389 | -0.019 | 0.3836 | No | ||
| 34 | FYN | 3375 3395 20052 | 9588 | -0.022 | 0.3733 | No | ||
| 35 | NFATC4 | 22002 | 11337 | -0.054 | 0.2801 | No | ||
| 36 | CALM1 | 21184 | 11604 | -0.060 | 0.2668 | No | ||
| 37 | PRKCA | 20174 | 11681 | -0.062 | 0.2638 | No | ||
| 38 | TRB@ | 1157 | 12184 | -0.079 | 0.2381 | No | ||
| 39 | MAP2K4 | 20405 | 15684 | -0.770 | 0.0631 | No | ||
| 40 | PPP3CA | 1863 5284 | 15979 | -0.995 | 0.0645 | No | ||
| 41 | NFKBIA | 21065 | 16384 | -1.316 | 0.0655 | No | ||
| 42 | MAPK8 | 6459 | 16452 | -1.403 | 0.0861 | No | ||
| 43 | HRAS | 4868 | 16802 | -1.753 | 0.0977 | No |
