Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
| Upregulated in class | transDMproB |
| GeneSet | ST_T_CELL_SIGNAL_TRANSDUCTION |
| Enrichment Score (ES) | 0.6912186 |
| Normalized Enrichment Score (NES) | 1.5612713 |
| Nominal p-value | 0.0066079297 |
| FDR q-value | 0.157749 |
| FWER p-Value | 0.795 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LAT | 17643 | 116 | 7.434 | 0.1148 | Yes | ||
| 2 | VAV1 | 23173 | 347 | 5.300 | 0.1886 | Yes | ||
| 3 | RASGRP2 | 9693 | 358 | 5.214 | 0.2730 | Yes | ||
| 4 | NFKB2 | 23810 | 491 | 4.513 | 0.3393 | Yes | ||
| 5 | NFKBIL1 | 23002 | 606 | 4.048 | 0.3991 | Yes | ||
| 6 | PAK4 | 17909 | 660 | 3.824 | 0.4585 | Yes | ||
| 7 | MAPK1 | 1642 11167 | 721 | 3.643 | 0.5145 | Yes | ||
| 8 | LCK | 15746 | 786 | 3.491 | 0.5679 | Yes | ||
| 9 | DAG1 | 18996 8837 | 1293 | 2.333 | 0.5787 | Yes | ||
| 10 | NFKBIE | 23225 1556 | 1402 | 2.139 | 0.6077 | Yes | ||
| 11 | SOS2 | 21049 | 1479 | 2.025 | 0.6365 | Yes | ||
| 12 | GRB2 | 20149 | 1534 | 1.943 | 0.6653 | Yes | ||
| 13 | NFKB1 | 15160 | 1611 | 1.847 | 0.6912 | Yes | ||
| 14 | CSK | 8805 | 2115 | 1.299 | 0.6853 | No | ||
| 15 | PAK1 | 9527 | 2767 | 0.720 | 0.6620 | No | ||
| 16 | RAF1 | 17035 | 2978 | 0.564 | 0.6598 | No | ||
| 17 | EPHB2 | 4675 2440 8910 | 3029 | 0.541 | 0.6660 | No | ||
| 18 | CD3D | 19473 | 3103 | 0.500 | 0.6702 | No | ||
| 19 | RASGRP4 | 6119 | 3284 | 0.411 | 0.6672 | No | ||
| 20 | RASGRP1 | 5360 14476 9694 | 3731 | 0.247 | 0.6472 | No | ||
| 21 | NFKBIB | 17906 | 4009 | 0.178 | 0.6352 | No | ||
| 22 | NFAT5 | 3921 7037 12036 | 4055 | 0.171 | 0.6355 | No | ||
| 23 | CTLA4 | 14238 | 4056 | 0.171 | 0.6383 | No | ||
| 24 | CD28 | 14239 4092 | 4275 | 0.138 | 0.6288 | No | ||
| 25 | ITPKB | 3963 14028 | 4520 | 0.105 | 0.6174 | No | ||
| 26 | ZAP70 | 14271 4042 | 4655 | 0.091 | 0.6116 | No | ||
| 27 | SOS1 | 5476 | 4708 | 0.086 | 0.6102 | No | ||
| 28 | GRAP2 | 5113 9398 | 5961 | 0.034 | 0.5434 | No | ||
| 29 | PTPRC | 5327 9662 | 6953 | 0.015 | 0.4903 | No | ||
| 30 | PLCG1 | 14753 | 7414 | 0.008 | 0.4656 | No | ||
| 31 | PAK3 | 9528 | 8538 | -0.007 | 0.4053 | No | ||
| 32 | ITK | 4934 | 8570 | -0.008 | 0.4038 | No | ||
| 33 | NCK1 | 9447 5152 | 8993 | -0.014 | 0.3813 | No | ||
| 34 | PAK7 | 14417 | 9324 | -0.018 | 0.3638 | No | ||
| 35 | FBXW7 | 1805 11928 | 11871 | -0.068 | 0.2278 | No | ||
| 36 | CBL | 19154 | 13840 | -0.189 | 0.1250 | No | ||
| 37 | LCP2 | 4988 9268 | 14367 | -0.258 | 0.1008 | No | ||
| 38 | RASGRP3 | 10767 | 15426 | -0.608 | 0.0538 | No | ||
| 39 | ITPKA | 14898 | 15875 | -0.916 | 0.0445 | No | ||
| 40 | PAK2 | 10310 5875 | 16358 | -1.281 | 0.0395 | No | ||
| 41 | NFKBIA | 21065 | 16384 | -1.316 | 0.0595 | No | ||
| 42 | DTYMK | 5776 | 17856 | -3.721 | 0.0409 | No |
