Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
| Upregulated in class | DMpreB |
| GeneSet | PYRIMIDINE_METABOLISM |
| Enrichment Score (ES) | -0.69956833 |
| Normalized Enrichment Score (NES) | -1.6007115 |
| Nominal p-value | 0.003717472 |
| FDR q-value | 0.06179024 |
| FWER p-Value | 0.477 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | DCK | 16808 | 192 | 6.569 | 0.0406 | No | ||
| 2 | RRM2 | 5401 5400 | 571 | 4.235 | 0.0531 | No | ||
| 3 | UCK1 | 10254 5831 10253 | 1283 | 2.344 | 0.0330 | No | ||
| 4 | POLD1 | 17847 | 1481 | 2.020 | 0.0380 | No | ||
| 5 | POLS | 9963 | 1634 | 1.812 | 0.0439 | No | ||
| 6 | TK2 | 18779 | 1824 | 1.608 | 0.0462 | No | ||
| 7 | RRM1 | 18163 | 2252 | 1.164 | 0.0322 | No | ||
| 8 | NP | 22027 9597 5273 5274 | 2722 | 0.766 | 0.0129 | No | ||
| 9 | TXNRD1 | 19923 | 3048 | 0.530 | -0.0005 | No | ||
| 10 | UPP1 | 20947 1385 | 4044 | 0.173 | -0.0528 | No | ||
| 11 | TK1 | 1457 10182 5762 | 4377 | 0.122 | -0.0697 | No | ||
| 12 | CTPS2 | 12060 2571 | 4426 | 0.116 | -0.0714 | No | ||
| 13 | ITPA | 9193 | 5267 | 0.056 | -0.1162 | No | ||
| 14 | POLR2C | 9750 | 5936 | 0.034 | -0.1519 | No | ||
| 15 | TYMS | 5810 5809 3606 3598 | 7118 | 0.012 | -0.2155 | No | ||
| 16 | DPYS | 22305 | 8327 | -0.005 | -0.2805 | No | ||
| 17 | CANT1 | 13304 | 9398 | -0.019 | -0.3380 | No | ||
| 18 | ENTPD1 | 4495 | 9917 | -0.027 | -0.3657 | No | ||
| 19 | POLR2B | 16817 | 10054 | -0.030 | -0.3728 | No | ||
| 20 | POLQ | 13407 22768 | 10704 | -0.040 | -0.4074 | No | ||
| 21 | DPYD | 15437 | 11226 | -0.051 | -0.4351 | No | ||
| 22 | UPB1 | 19988 3389 | 11908 | -0.069 | -0.4712 | No | ||
| 23 | CDA | 15702 | 12600 | -0.097 | -0.5077 | No | ||
| 24 | AK3L1 | 8564 | 14390 | -0.262 | -0.6020 | No | ||
| 25 | NT5E | 19360 18702 | 14728 | -0.340 | -0.6175 | No | ||
| 26 | POLRMT | 19705 | 14966 | -0.404 | -0.6272 | No | ||
| 27 | POLB | 9599 | 15405 | -0.596 | -0.6461 | No | ||
| 28 | NUDT2 | 16239 | 15441 | -0.622 | -0.6432 | No | ||
| 29 | POLR2A | 5394 | 15814 | -0.870 | -0.6565 | No | ||
| 30 | POLL | 23658 3688 | 15940 | -0.971 | -0.6557 | No | ||
| 31 | ECGF1 | 22160 | 16080 | -1.039 | -0.6551 | No | ||
| 32 | POLR2I | 12839 | 16178 | -1.117 | -0.6517 | No | ||
| 33 | UMPS | 22606 1760 | 16613 | -1.563 | -0.6629 | No | ||
| 34 | POLR2E | 3325 19699 | 17221 | -2.334 | -0.6775 | Yes | ||
| 35 | POLE | 16755 | 17631 | -3.130 | -0.6753 | Yes | ||
| 36 | POLG | 17789 | 17827 | -3.636 | -0.6576 | Yes | ||
| 37 | POLR2G | 23753 | 17842 | -3.679 | -0.6298 | Yes | ||
| 38 | DTYMK | 5776 | 17856 | -3.721 | -0.6017 | Yes | ||
| 39 | POLR2J | 16672 | 17905 | -3.892 | -0.5741 | Yes | ||
| 40 | POLR2K | 9413 | 17988 | -4.160 | -0.5462 | Yes | ||
| 41 | CTPS | 2514 15772 | 18007 | -4.223 | -0.5145 | Yes | ||
| 42 | NT5M | 8345 4175 | 18037 | -4.318 | -0.4825 | Yes | ||
| 43 | POLR2H | 10888 | 18043 | -4.355 | -0.4490 | Yes | ||
| 44 | UNG | 10257 16744 | 18161 | -4.819 | -0.4180 | Yes | ||
| 45 | NT5C | 20151 | 18198 | -4.950 | -0.3815 | Yes | ||
| 46 | DHODH | 7152 | 18357 | -5.661 | -0.3461 | Yes | ||
| 47 | CAD | 16886 | 18408 | -6.035 | -0.3020 | Yes | ||
| 48 | POLD2 | 20537 | 18484 | -6.826 | -0.2532 | Yes | ||
| 49 | NME1 | 9467 | 18515 | -7.106 | -0.1997 | Yes | ||
| 50 | NME2 | 9468 | 18538 | -7.449 | -0.1431 | Yes | ||
| 51 | DCTD | 18620 | 18594 | -9.062 | -0.0758 | Yes | ||
| 52 | POLR1B | 14857 | 18608 | -9.919 | 0.0004 | Yes |
