Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos
Phenotype	phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos
Upregulated in class	DMpreB
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	-0.5997655
Normalized Enrichment Score (NES)	-1.551558
Nominal p-value	0.0017574693
FDR q-value	0.103563614
FWER p-Value	0.782

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IMPDH1	17197 1131	3	10.857	0.0413	No
2	GMPR	21651	10	10.380	0.0806	No
3	DCK	16808	192	6.569	0.0959	No
4	RRM2	5401 5400	571	4.235	0.0916	No
5	PDE2A	18170	873	3.262	0.0877	No
6	ZNRD1	1491 22987	983	2.983	0.0932	No
7	ADA	2703 14361	1193	2.543	0.0916	No
8	AK2	8563 2479 16073	1221	2.493	0.0997	No
9	PAPSS1	15419	1245	2.431	0.1077	No
10	DGUOK	17099 1041	1361	2.209	0.1099	No
11	POLD1	17847	1481	2.020	0.1112	No
12	PKM2	3642 9573	1619	1.831	0.1108	No
13	POLD3	17742	1682	1.745	0.1141	No
14	PDE4B	9543	1822	1.611	0.1127	No
15	POLD4	12822	1902	1.515	0.1142	No
16	XDH	22897	2061	1.345	0.1108	No
17	ADCY9	22680	2147	1.272	0.1111	No
18	RRM1	18163	2252	1.164	0.1099	No
19	NT5C2	3768 8052	2316	1.102	0.1107	No
20	PDE3B	5236	2321	1.097	0.1147	No
21	HPRT1	2655 24339 408	2601	0.873	0.1029	No
22	NP	22027 9597 5273 5274	2722	0.766	0.0993	No
23	PDE5A	15431	3034	0.537	0.0846	No
24	POLR1A	9749 5393	3076	0.513	0.0843	No
25	GUCY1B3	15311	3192	0.453	0.0798	No
26	ADCY6	22139 2283 8551	3656	0.270	0.0558	No
27	PDE4C	8481	3857	0.217	0.0458	No
28	PDE4D	10722 6235	4135	0.158	0.0314	No
29	PDE6H	17257	4209	0.146	0.0280	No
30	AK1	4363	4308	0.133	0.0233	No
31	NPR2	16230	4395	0.119	0.0191	No
32	GDA	4764	4568	0.098	0.0101	No
33	GUCY1A3	7216 12245 15310	4572	0.098	0.0103	No
34	ITPA	9193	5267	0.056	-0.0270	No
35	POLR2C	9750	5936	0.034	-0.0630	No
36	AMPD1	5051	6145	0.030	-0.0741	No
37	ADCY5	10312	6281	0.027	-0.0813	No
38	PDE11A	10805	6288	0.027	-0.0815	No
39	PKLR	1850 15545	6419	0.024	-0.0885	No
40	PDE6G	20119	6539	0.022	-0.0948	No
41	POLA1	24112	6819	0.017	-0.1099	No
42	PAPSS2	6258	6978	0.014	-0.1184	No
43	ENPP3	19803	7572	0.005	-0.1504	No
44	GMPR2	2711	7601	0.005	-0.1519	No
45	POLE2	21053	7971	0.000	-0.1719	No
46	GUCY2F	24045	8251	-0.003	-0.1869	No
47	POLR3K	12447 7372	8411	-0.006	-0.1955	No
48	ENTPD3	19266	8468	-0.006	-0.1985	No
49	PDE1C	5235	8764	-0.010	-0.2144	No
50	AK5	6042	8951	-0.013	-0.2245	No
51	GUCY2C	1140 16954	9096	-0.015	-0.2322	No
52	ALLC	21093 2130	9250	-0.017	-0.2404	No
53	NME7	926 4101 14070 3986 3946 931	9369	-0.019	-0.2467	No
54	CANT1	13304	9398	-0.019	-0.2481	No
55	ADK	3302 3454 8555	9441	-0.020	-0.2503	No
56	ENTPD2	8713	9449	-0.020	-0.2506	No
57	PDE1A	9541 5234	9653	-0.023	-0.2615	No
58	ADCY8	22281	9741	-0.024	-0.2661	No
59	NPR1	9480	9834	-0.026	-0.2710	No
60	ENTPD1	4495	9917	-0.027	-0.2754	No
61	POLR2B	16817	10054	-0.030	-0.2826	No
62	AMPD3	4383 2110	10111	-0.030	-0.2855	No
63	AMPD2	1931 15197	10189	-0.032	-0.2896	No
64	PDE9A	23301	10515	-0.037	-0.3070	No
65	PDE7B	19807	11236	-0.051	-0.3457	No
66	GUCY1A2	19580	11338	-0.054	-0.3510	No
67	ADCY4	2980 21818	11398	-0.055	-0.3540	No
68	ENTPD8	12996	11840	-0.067	-0.3776	No
69	PDE8A	18202	12014	-0.073	-0.3867	No
70	PDE8B	5756	12107	-0.076	-0.3913	No
71	RRM2B	6902 6903 11801	12691	-0.101	-0.4225	No
72	NT5C1B	21315	12830	-0.109	-0.4295	No
73	ADCY2	21412	13035	-0.121	-0.4401	No
74	ENTPD6	4496 2678	13526	-0.158	-0.4660	No
75	ENTPD5	4497	14246	-0.240	-0.5040	No
76	AK3L1	8564	14390	-0.262	-0.5107	No
77	PDE4A	3037 19542 3083 3023	14605	-0.307	-0.5211	No
78	ADCY3	21329 894	14643	-0.316	-0.5219	No
79	NT5E	19360 18702	14728	-0.340	-0.5252	No
80	PDE10A	23387	14749	-0.346	-0.5249	No
81	NUDT2	16239	15441	-0.622	-0.5599	No
82	PNPT1	20936	15655	-0.746	-0.5686	No
83	POLR2A	5394	15814	-0.870	-0.5738	No
84	ENPP1	19804	15834	-0.885	-0.5715	No
85	ECGF1	22160	16080	-1.039	-0.5808	No
86	POLR2I	12839	16178	-1.117	-0.5817	No
87	POLE4	12441	16204	-1.143	-0.5787	No
88	ADSSL1	21136 2087	16246	-1.178	-0.5765	No
89	PAICS	16820	16678	-1.613	-0.5936	Yes
90	POLR3H	13460 8135	16747	-1.684	-0.5909	Yes
91	PDE7A	9544 1788	16836	-1.794	-0.5888	Yes
92	ADCY7	8552 448	16937	-1.943	-0.5868	Yes
93	PRPS2	24003	17118	-2.200	-0.5881	Yes
94	NME4	23065 1577	17127	-2.204	-0.5801	Yes
95	PRIM1	19847	17128	-2.204	-0.5717	Yes
96	POLR3A	21900	17155	-2.229	-0.5646	Yes
97	PRPS1	24233	17165	-2.238	-0.5565	Yes
98	POLR2E	3325 19699	17221	-2.334	-0.5506	Yes
99	NT5C3	17136	17316	-2.573	-0.5459	Yes
100	POLR1D	3593 3658 16623	17578	-3.037	-0.5484	Yes
101	POLE	16755	17631	-3.130	-0.5393	Yes
102	FHIT	21920	17694	-3.306	-0.5300	Yes
103	POLA2	23988	17757	-3.452	-0.5202	Yes
104	POLR2G	23753	17842	-3.679	-0.5107	Yes
105	ENTPD4	7449	17875	-3.773	-0.4980	Yes
106	POLR2J	16672	17905	-3.892	-0.4847	Yes
107	RFC5	13005 7791	17920	-3.951	-0.4704	Yes
108	POLE3	7200	17972	-4.110	-0.4575	Yes
109	POLR2K	9413	17988	-4.160	-0.4424	Yes
110	NT5M	8345 4175	18037	-4.318	-0.4285	Yes
111	POLR2H	10888	18043	-4.355	-0.4122	Yes
112	NUDT9	7897	18103	-4.597	-0.3978	Yes
113	NME6	3139 19297	18170	-4.853	-0.3829	Yes
114	GMPS	15578	18194	-4.945	-0.3652	Yes
115	NT5C	20151	18198	-4.950	-0.3465	Yes
116	APRT	8620	18310	-5.406	-0.3319	Yes
117	ADSL	4358	18353	-5.627	-0.3127	Yes
118	IMPDH2	10730	18355	-5.639	-0.2912	Yes
119	NUDT5	15121	18421	-6.118	-0.2714	Yes
120	GUK1	20432	18423	-6.134	-0.2480	Yes
121	GART	22543 1754	18431	-6.196	-0.2247	Yes
122	POLD2	20537	18484	-6.826	-0.2015	Yes
123	NME1	9467	18515	-7.106	-0.1760	Yes
124	PPAT	6081	18522	-7.211	-0.1488	Yes
125	ATIC	14231 3968	18524	-7.214	-0.1213	Yes
126	NME2	9468	18538	-7.449	-0.0936	Yes
127	PDE6D	13897 3945	18552	-7.756	-0.0647	Yes
128	POLR3B	12875	18557	-7.903	-0.0347	Yes
129	POLR1B	14857	18608	-9.919	0.0004	Yes