Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
| Upregulated in class | DMpreB |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | -0.74227494 |
| Normalized Enrichment Score (NES) | -1.6426892 |
| Nominal p-value | 0.003944773 |
| FDR q-value | 0.044719663 |
| FWER p-Value | 0.23 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | POLD1 | 17847 | 1481 | 2.020 | -0.0547 | No | ||
| 2 | POLD3 | 17742 | 1682 | 1.745 | -0.0439 | No | ||
| 3 | POLD4 | 12822 | 1902 | 1.515 | -0.0370 | No | ||
| 4 | MCM4 | 22655 1708 | 1971 | 1.440 | -0.0228 | No | ||
| 5 | CDK2 | 3438 3373 19592 3322 | 2032 | 1.374 | -0.0090 | No | ||
| 6 | ORC2L | 385 13949 | 2822 | 0.677 | -0.0431 | No | ||
| 7 | RPS27A | 13433 | 4066 | 0.169 | -0.1080 | No | ||
| 8 | RFC1 | 16527 | 5202 | 0.058 | -0.1683 | No | ||
| 9 | ORC1L | 327 16144 | 6252 | 0.027 | -0.2245 | No | ||
| 10 | MCM6 | 4000 13845 4119 | 7085 | 0.013 | -0.2691 | No | ||
| 11 | POLE2 | 21053 | 7971 | 0.000 | -0.3167 | No | ||
| 12 | CDC45L | 22642 1752 | 9842 | -0.026 | -0.4171 | No | ||
| 13 | UBA52 | 10239 | 11370 | -0.054 | -0.4986 | No | ||
| 14 | CDC6 | 6221 6220 | 11383 | -0.055 | -0.4986 | No | ||
| 15 | CDC7 | 16765 3477 | 11672 | -0.062 | -0.5133 | No | ||
| 16 | UBC | 14 14 10241 15 16 | 11786 | -0.065 | -0.5186 | No | ||
| 17 | PRIM2A | 13986 | 12760 | -0.105 | -0.5697 | No | ||
| 18 | ORC4L | 11172 6460 | 14118 | -0.221 | -0.6400 | No | ||
| 19 | PCNA | 9535 | 14386 | -0.261 | -0.6511 | No | ||
| 20 | UBB | 10240 | 15516 | -0.662 | -0.7037 | No | ||
| 21 | RPA1 | 20349 | 15517 | -0.662 | -0.6955 | No | ||
| 22 | RPA2 | 2330 16057 | 16016 | -1.005 | -0.7099 | No | ||
| 23 | MCM5 | 18564 | 16079 | -1.039 | -0.7004 | No | ||
| 24 | ORC3L | 6941 | 16858 | -1.822 | -0.7197 | Yes | ||
| 25 | NACA | 9444 5147 | 16929 | -1.928 | -0.6996 | Yes | ||
| 26 | PRIM1 | 19847 | 17128 | -2.204 | -0.6830 | Yes | ||
| 27 | MCM2 | 17074 | 17133 | -2.214 | -0.6559 | Yes | ||
| 28 | MCM10 | 14694 | 17609 | -3.085 | -0.6433 | Yes | ||
| 29 | CDT1 | 18437 | 17628 | -3.127 | -0.6056 | Yes | ||
| 30 | POLE | 16755 | 17631 | -3.130 | -0.5669 | Yes | ||
| 31 | GMNN | 21513 | 17632 | -3.131 | -0.5282 | Yes | ||
| 32 | MCM3 | 13991 | 17716 | -3.357 | -0.4912 | Yes | ||
| 33 | RPA3 | 12667 | 17754 | -3.445 | -0.4505 | Yes | ||
| 34 | POLA2 | 23988 | 17757 | -3.452 | -0.4079 | Yes | ||
| 35 | RFC5 | 13005 7791 | 17920 | -3.951 | -0.3678 | Yes | ||
| 36 | ORC6L | 18539 | 18101 | -4.596 | -0.3206 | Yes | ||
| 37 | RFC3 | 12786 | 18116 | -4.657 | -0.2637 | Yes | ||
| 38 | MCM7 | 9372 3568 | 18211 | -4.973 | -0.2073 | Yes | ||
| 39 | RFC4 | 1735 22627 | 18260 | -5.128 | -0.1464 | Yes | ||
| 40 | ORC5L | 11173 3595 | 18464 | -6.552 | -0.0763 | Yes | ||
| 41 | POLD2 | 20537 | 18484 | -6.826 | 0.0071 | Yes |
