Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
| Upregulated in class | DMpreB |
| GeneSet | REACTOME_DNA_REPLICATION |
| Enrichment Score (ES) | -0.6885366 |
| Normalized Enrichment Score (NES) | -1.6359522 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.022482606 |
| FWER p-Value | 0.401 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PSMB9 | 23021 | 323 | 5.459 | 0.0205 | No | ||
| 2 | PSMB2 | 2324 16078 | 711 | 3.670 | 0.0251 | No | ||
| 3 | POLD1 | 17847 | 1481 | 2.020 | -0.0024 | No | ||
| 4 | POLD3 | 17742 | 1682 | 1.745 | -0.0011 | No | ||
| 5 | MCM4 | 22655 1708 | 1971 | 1.440 | -0.0066 | No | ||
| 6 | CDK2 | 3438 3373 19592 3322 | 2032 | 1.374 | -0.0003 | No | ||
| 7 | PSMA3 | 9632 5298 | 2673 | 0.808 | -0.0292 | No | ||
| 8 | ORC2L | 385 13949 | 2822 | 0.677 | -0.0325 | No | ||
| 9 | PSME1 | 5300 9637 | 3070 | 0.516 | -0.0422 | No | ||
| 10 | PSMD10 | 2578 2597 24046 | 3127 | 0.485 | -0.0419 | No | ||
| 11 | PSMB10 | 5299 18761 | 3162 | 0.463 | -0.0405 | No | ||
| 12 | LIG1 | 18388 1749 1493 | 3446 | 0.342 | -0.0534 | No | ||
| 13 | RB1 | 21754 | 3542 | 0.305 | -0.0564 | No | ||
| 14 | RFC1 | 16527 | 5202 | 0.058 | -0.1454 | No | ||
| 15 | ORC1L | 327 16144 | 6252 | 0.027 | -0.2018 | No | ||
| 16 | PSMA6 | 21270 | 6335 | 0.025 | -0.2060 | No | ||
| 17 | POLA1 | 24112 | 6819 | 0.017 | -0.2320 | No | ||
| 18 | MCM6 | 4000 13845 4119 | 7085 | 0.013 | -0.2462 | No | ||
| 19 | PSMA1 | 1627 17669 | 7334 | 0.009 | -0.2595 | No | ||
| 20 | POLE2 | 21053 | 7971 | 0.000 | -0.2937 | No | ||
| 21 | CDC45L | 22642 1752 | 9842 | -0.026 | -0.3944 | No | ||
| 22 | PSMD5 | 2774 14612 | 10407 | -0.035 | -0.4245 | No | ||
| 23 | CDC7 | 16765 3477 | 11672 | -0.062 | -0.4923 | No | ||
| 24 | PSMD11 | 12772 7600 | 13078 | -0.123 | -0.5672 | No | ||
| 25 | ORC4L | 11172 6460 | 14118 | -0.221 | -0.6216 | No | ||
| 26 | PSMC3 | 9636 | 14271 | -0.243 | -0.6281 | No | ||
| 27 | PCNA | 9535 | 14386 | -0.261 | -0.6325 | No | ||
| 28 | PSMA2 | 9631 | 14554 | -0.293 | -0.6395 | No | ||
| 29 | E2F2 | 6327 10824 6839 | 14926 | -0.393 | -0.6567 | No | ||
| 30 | RPA1 | 20349 | 15517 | -0.662 | -0.6839 | Yes | ||
| 31 | PSMB6 | 9634 | 15579 | -0.698 | -0.6824 | Yes | ||
| 32 | PSMB4 | 15252 | 15677 | -0.765 | -0.6823 | Yes | ||
| 33 | PSMD4 | 15251 | 15753 | -0.824 | -0.6806 | Yes | ||
| 34 | FEN1 | 8961 | 15855 | -0.898 | -0.6798 | Yes | ||
| 35 | RPA2 | 2330 16057 | 16016 | -1.005 | -0.6815 | Yes | ||
| 36 | MCM5 | 18564 | 16079 | -1.039 | -0.6776 | Yes | ||
| 37 | PSMA5 | 6464 | 16241 | -1.174 | -0.6782 | Yes | ||
| 38 | PSMC6 | 7379 | 16310 | -1.237 | -0.6733 | Yes | ||
| 39 | PSMD3 | 5803 | 16523 | -1.485 | -0.6744 | Yes | ||
| 40 | PSMD8 | 7166 | 16675 | -1.611 | -0.6713 | Yes | ||
| 41 | PSMA4 | 11179 | 16871 | -1.842 | -0.6691 | Yes | ||
| 42 | PSMC4 | 2141 17915 | 16976 | -1.996 | -0.6608 | Yes | ||
| 43 | PSMC1 | 9635 | 17026 | -2.067 | -0.6491 | Yes | ||
| 44 | PSMB1 | 23118 | 17038 | -2.079 | -0.6353 | Yes | ||
| 45 | PRIM1 | 19847 | 17128 | -2.204 | -0.6248 | Yes | ||
| 46 | MCM2 | 17074 | 17133 | -2.214 | -0.6097 | Yes | ||
| 47 | PSMB3 | 11180 | 17536 | -2.970 | -0.6107 | Yes | ||
| 48 | MCM10 | 14694 | 17609 | -3.085 | -0.5932 | Yes | ||
| 49 | PSMD12 | 20621 | 17621 | -3.111 | -0.5722 | Yes | ||
| 50 | POLE | 16755 | 17631 | -3.130 | -0.5510 | Yes | ||
| 51 | GMNN | 21513 | 17632 | -3.131 | -0.5293 | Yes | ||
| 52 | PSMD9 | 3461 7393 | 17635 | -3.147 | -0.5075 | Yes | ||
| 53 | PSMC2 | 16909 | 17677 | -3.270 | -0.4871 | Yes | ||
| 54 | MCM3 | 13991 | 17716 | -3.357 | -0.4658 | Yes | ||
| 55 | PSMB5 | 9633 | 17739 | -3.411 | -0.4433 | Yes | ||
| 56 | RPA3 | 12667 | 17754 | -3.445 | -0.4202 | Yes | ||
| 57 | POLA2 | 23988 | 17757 | -3.452 | -0.3964 | Yes | ||
| 58 | PSMA7 | 14318 | 17880 | -3.794 | -0.3766 | Yes | ||
| 59 | RFC5 | 13005 7791 | 17920 | -3.951 | -0.3513 | Yes | ||
| 60 | PSMC5 | 1348 20624 | 17937 | -3.998 | -0.3244 | Yes | ||
| 61 | PSMD14 | 15005 | 17987 | -4.160 | -0.2982 | Yes | ||
| 62 | RFC3 | 12786 | 18116 | -4.657 | -0.2728 | Yes | ||
| 63 | PSME3 | 20657 | 18155 | -4.800 | -0.2415 | Yes | ||
| 64 | MCM7 | 9372 3568 | 18211 | -4.973 | -0.2100 | Yes | ||
| 65 | PSMD2 | 10137 5724 | 18238 | -5.062 | -0.1763 | Yes | ||
| 66 | RFC4 | 1735 22627 | 18260 | -5.128 | -0.1418 | Yes | ||
| 67 | ORC5L | 11173 3595 | 18464 | -6.552 | -0.1073 | Yes | ||
| 68 | POLD2 | 20537 | 18484 | -6.826 | -0.0610 | Yes | ||
| 69 | PSMD7 | 18752 3825 | 18607 | -9.809 | 0.0005 | Yes |
